Fluorine-18-Labeled Positron Emission Tomography Probe Targeting Activated p38α: Design, Synthesis, and In Vivo Evaluation in Rodents by Mikiya Futatsugi, Anna Miyazaki, Yasukazu Kanai, Naoya Kondo, Takashi Temma

“…PET/CT imaging successfully visualized BAT with high contrast. <b>Conclusions:</b> These results suggest that [¹⁸F]R1487 is a promising PET probe for imaging activated p38α in vivo, which has potential applications for pathophysiological conditions such as inflammation, cancer, and metabolic disorders.…”
Get full text

Unilateral biportal endoscopy versus percutaneous endoscopic lumbar discectomy for lumbar disc herniation: a comparative study of clinical efficacy and radiological outcomes by Dongyue Li, Luming Tao, Xinuo Zhang, Qingjun Su, Bo Yin

“…The aim of this study is to compare the clinical efficacy and radiological outcomes between UBE and PELD in the treatment of LDH. Methods A retrospective analysis was conducted on 108 patients with LDH treated with spinal endoscopy in our hospital from January 2021 to July 2023. …”
Get full text

Association of Serum Uric Acid With Relative Muscle Loss: A US Population–Based Cross‐Sectional Study by Fuquan Wang, Lin Wen, Xiaopeng Guo, Weiwei Wang, Yanyan Cao, Guofeng Zhou, Jun Wang, Chuansheng Zheng

“…We sought to investigate the association of SUA levels with relative muscle loss in the National Health and Nutrition Examination Survey (NHANES) 2011–2018. Methods Relative muscle loss was defined by the Foundation for the National Institutes of Health (FNIH) as characterized by appendicular lean mass (ALM) adjusted by BMI (ALM/BMI) < 0.512 for women and < 0.789 for men. …”
Get full text

Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer... by Saurabh Mehta, Ajit R. Mahale, Dias Tina Thomas, Prajwal Prabhudev Mane, Atmananda S Hegde, Charu Eapen

“…Pre- and post-intervention assessments included pain (Visual Analog Scale, VAS), patient-reported outcomes (Knee Injury and Osteoarthritis Outcome Score, KOOS), physical function tests (30-second sit-to-stand, 40-meter fast-paced walk, stair climb, timed up-and-go), and knee muscle strength and core endurance. …”
Get full text

Midterm Outcomes of Transfibular Total Ankle Arthroplasty: Clinical and Radiographic Analysis of 130 Cases with Minimum 5-Year Follow-Up by Jonathan Day MD, Amanda N. Fletcher MD, MSc, Morgan Motsay BS, Maggie K. Manchester BS, Mark Arthur MD, Zijun Zhang PhD, MD, Lew C. Schon MD

“…PROMs included: 12-item Short Form Health Survey (SF-12) physical (PCS) and mental (MCS) component scores, Ankle Osteoarthritis Scale (OAS), and Visual Analog Scale (VAS). Functional outcomes included range of motion (ROM) measured on weightbearing ROM radiographs. …”
Get full text

Clinical efficacy of one-hole split endoscopy vs. unilateral biportal endoscopy for the treatment of single-segment lumbar spinal stenosis: a retrospective study with 2-year follow... by Peidong Qing, Wenlong Guo, Shiming Xie, Shengxin Zhao, Liqiang Cui, Mingfan Li, Shuangquan Gong, Youpeng Hu

“…This study aimed to compare the long-term efficacy of OSE and unilateral biportal endoscopy (UBE) in LSS treatment.MethodsThe clinical data of 77 patients diagnosed with LSS at our hospital between January 2020 and March 2022 were retrospectively analyzed. …”
Get full text

Validity and Feasibility of the Seated Medicine Ball Throw and Unilateral Shot-Put Tests in Assessing Upper Extremity Function in Rotator-Cuff-Related Shoulder Pain by Michal Linkovski, Jeremy Lewis, Hilla Sarig Bahat

“…Pain was assessed using a 10 cm visual analog scale (VAS) at multiple time points. …”
Get full text

Comparative Efficacy of Different Exercise Therapies for Cardiorespiratory Fitness in Breast Cancer Survivors: A Systematic Review and Bayesian Network Meta-analysis by Xue Zhou, Yao Yang, Liwen Zhai, Jianing Gan, Conghui Li, Yi Zhu

“…A network graph was constructed to visualize the relative relationship for each exercise therapy in relation to the others. …”
Get full text

Partial femoral head replacement: a new innovative surgical technique for precise minimally invasive treatment of association research circulation osseous stage III femoral head ne... by Tianyu Wang, Zhongzheng Wang, Yuchuan Wang, Changhui Li, Yining Lu, Yanbin Zhu, Wei Chen, Xuebin Zhang, Yingze Zhang

“…Clinical scores, including the visual analogue scale (VAS) score, Harris Hip Score (HHS), and 12-Item Short-Form Health Survey (SF-12) scores, were determined. …”
Get full text

Quantitative analysis of retinal vascular parameters changes in school-age children with refractive error using artificial intelligence by Linlin Liu, Lijie Zhong, Linggeng Zeng, Fang Liu, Xinghui Yu, Lianfeng Xie, Shuxiang Tan, Shuang Zhang, Yi-Ping Jiang

“…All participants underwent a series of examinations, including naked-eye and best-corrected visual acuity, cycloplegic spherical equivalent refraction, intraocular pressure measurement, ocular axial measurement (AL), and color fundus photography. …”
Get full text

Migraine and its childhood equivalents by P. V. Zhmyleva, G. R. Tabeeva

“…A structured diagnostic interview was conducted with all study participants (or their parents) and pain and anxiety were assessed using special scales and tests adapted for children (visual analog scale (VAS); Digital Pain Rating Scale (DPS); Verbal Rating Pain Scale (VRPS), Faces Pain Scale (FPS), MIDAS scales, Hands scale, depression scales adapted by T.I. …”
Get full text

Performance of OncoE6TM Cervical Test in detecting cervical precancer lesions in HIV-positive women attending an HIV clinic in Bujumbura, Burundi: a cross-sectional study by Zacharie Ndizeye, Sonia Menon, Jean-Pierre Van Geertruyden, Catherine Sauvaget, Y Jacquemyn, John-Paul Bogers, Ina Benoy, Davy Vanden Broeck

“…To this end, we evaluated the clinical performance of the OncoE6 Cervical Test in detecting cervical intraepithelial neoplasia (CIN) among HIV-infected women in Bujumbura, Burundi.Methods From June to December 2017, a cross-sectional study was conducted in 680 HIV-positive women at the University Hospital. …”
Get full text

Clinical efficacy and radiological changes of proximal fibular osteotomy for medial compartment knee osteoarthritis: a systematic review and meta-analysis by Yu Jiang, Jingyuan Li, Liang Zhang, Xiaodong Jia, Tianrui Wang, Xia Zhao, Jinli Chen, Kuishuai Xu

“…The outcomes of interest were visual analog scale (VAS), knee function scores, radiological results, and complication rates. …”
Get full text

Clinical Study on Lumbar Disc Herniation Treated by Sling and Tuina Exercise Technique by Yi DING, Chenchen GUO, LI Li

“…Japanese Orthopaedic Association Scores(JOA)and VisualAnalogue Score(VAS)were used to evaluate the clinical efficacy before treatment and four weeks after treatment. …”
Get full text

Results from AD-HEARING (ADherence to and adjustment of HEARING aids in clinical routine care as preventive dementia strategy): a prospective 6-month follow-up study on cognition a... by Michael Belz, Sebastian Gmeinwieser, Mona Abdel-Hamid, Mona Abdel-Hamid, Robert Kühler, Jenny Blum, Philipp Hessmann, Nicola Strenzke, Claudia Bartels

“…Hearing aid use might reduce this risk by preserving cognitive and psychological functions.ObjectiveThis study aims to investigate the influence of ARHL and hearing aid use on cognition and different aspects of psychological well-being.MethodsDuring 05/2021 and 05/2023, 31 subjects with audiometrically confirmed ARHL were included and 28 underwent follow-up 6 months later (final analysis sample). …”
Get full text

Arthroscopic Margin Convergence Repair Without Suture Anchors Improves Clinical Outcomes for Full- and Partial-Thickness Rotator Cuff Tears by S. Ali Ghasemi, M.D., Benjamin Murray, D.O., Adam Lencer, D.O., Emily Schueppert, D.O., James Raphael, M.D., Craig Morgan, M.D., Arthur Bartolozzi, M.D.

“…Outcomes were assessed using the American Shoulder and Elbow Surgeons (ASES) shoulder score; University of California, Los Angeles (UCLA) shoulder score; and visual analog scale (VAS) score. A 2-tailed distribution paired t test was used to determine statistical significance (P < .05) between preoperative scores and scores at final follow-up. …”
Get full text

A COMPARISON OF THE EFFECTS OF BALANCE– PROPRIOCEPTION AND AEROBIC EXERCISES ON FUNCTIONAL STATUS, PAIN, AND BALANCE IN PATIENTS WITH FIBROMYALGIA SYNDROME - A RANDOMIZED CONTROLLE... by Hadi Yavuz, Türker Şahinkaya, Musa Doruk, Mert Zure, Şensu Dinçer, Ayşegül Ketenci, Gökhan Metin

“…This study aimed to compare the effects of aerobic and balance-proprioception exercises on pain, functional status, and balance in female patients with fibromyalgia.Material and Method: Female patients with fibromyalgia syndrome who applied to the university physical medicine and rehabilitation department clinic were evaluated for eligibility. …”
Get full text

The effectiveness of the REAL™, a school-based, virtual reality-integrated social emotional learning intervention to promote mental health for early Malaysian adolescents by Aimi Nur Athira Putri Baharuddin, Nik Ruzyanei Nik Jaafar, Normala Ibrahim, Abdul Rahman Ahmad Badayai, Hajar Mohd Salleh Sahimi, Nurul Ain Mohamad Kamal, Nur Husna Ismail, Ely Salwana, Mohd Pilus Abdullah, Mohd ‘Ammar Ihsan Ahmad Zamzuri

Get full text

Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Objective: To prospectively evaluate the long-term effects of orthognathic surgery on masticatory function in individuals with repaired complete cleft lip and palate and to compare the results with a control group. Material and methods: A total of 40 individuals were prospectively analyzed before (PRE-ORTHOG) and approximately 12 months after orthognathic surgery (POST-ORTHOG). …”
Get full text

The assessment of dupilumab in children with moderate-to-severe asthma and comorbid type 2 inflammatory diseases by Tingting Shi, Shuning Wu, Rongshan Chen, Yaping Xie, Genquan Yin, Chunhui He, Cuiping Liang, Gen Lu

“…The Patient-Oriented Eczema Measure(POEM) and Peak Pruritus Numerical Rating Scale(NRS), Rhinitis Four-point, and Rhinitis Visual Analogue Scale(VAS) scores were significantly lower than those at baseline (all P < 0.05). …”
Get full text