Maternal age-related declines in live birth rate following single euploid embryo transfer: a retrospective cohort study by Wei Jiang, Zichen Zheng, Nan Yan, Shuang Yao, Qijun Xie, Danyu Ni, Shanren Cao, Chun Zhao, Xiufeng Ling

“…Abstract Purpose To assess whether maternal age influences the pregnancy outcomes after single frozen euploid embryo transfer. Methods This retrospective analysis was conducted on 1037 cycles of single euploid embryo transfer performed at Nanjing Women and Children’s Healthcare Hospital between January 2016 and April 2023. …”
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Identification of tryptophan metabolism-related biomarkers for nonalcoholic fatty liver disease through network analysis by Cuihua Jiang, Jianqi Liang, Kaibo Hu, Yanqing Ye, Jiajia Yang, Xiaozhi Zhang, Guilin Ye, Jing Zhang, Deju Zhang, Bin Zhong, Peng Yu, Liefeng Wang, Bin Zeng

“…The R package limma and WGCNA were used to identify TMRGs–DEGs, and GO, KEGG and Cytoscape were used to analyze and visualize the data. Immune cell infiltration analysis was used to explore the immune mechanism of NAFLD and the biomarkers. …”
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The Efficacy of Hyaluronic Acid in Reducing Pelvic Adhesions in Patients Undergoing Gynecologic Laparoscopic Surgery: A Meta‐Analysis of Randomized Clinical Trials by Maryam Mazloomi, Arash Mohazzab, Kobra Tahermanesh, Maliheh Fakehi, Maryam Saeedzarandi, Zahra Kooshari, Paria Dehesh, Seyede Razieh Ghaffari

“…Potential publication bias was assessed through Egger's regression test and visual inspection of funnel plots. Results Hyaluronic acid gel significantly reduced moderate adhesions (RR: 0.32; 95% CI: 0.20–0.45) and overall adhesion severity (SMD: −1.31; 95% CI: −1.99 to −0.62). …”
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Modified transforaminal epidural steroid injection combined with pulsed radiofrequency: an effective treatment measure for lumbar radiculopathy by Qi Yan, Xianggu Zhong, Jiarong Li, Leyu Zhao, Junjie Niu, Dawei Song, Jinning Wang, Yun Teng, Tianyi Wu, Xiao Sun, Rui Chen, Shuangfei Wang, Jun Zou

“…Our findings indicated that this method can efficiently and swiftly relieve patients’ radicular discomfort and produce enduring therapeutic effects.…”
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Prediction of tumor deposits in stage I-III gastric cancer: a clinically applicable nomogram integrating clinicopathology outcomes by Kunjie Wang, Yue Huo, Yuanfang Zhang, Song Guo, Weiguang Yu, Na Xiao, Shenyong Su, Lin An

“…ObjectiveThis study seeks to identify clinicopathological risk factors associated with tumor deposits (TD) development in stage I-III gastric cancer patients and to construct a visualized predictive model for clinical application.MethodsA retrospective cohort of 1,284 gastric cancer patients treated at the Affiliated Hospital of Hebei University (September 2010–September 2022) was analyzed. …”
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Clinicopathological features of cranial-nasal-orbital communicating lesions and diagnostic indicators for differentiating benign and malignant neoplasms by Meng Xie, Jin Chen, Ya-Yan You, Zi-Xuan Su, Xi-Yin Zhu, Xing-Hua Wang, Peng-Cheng Li, Fa-Gang Jiang

“…CONCLUSION: Malignant cranial-nasal-orbital communicating lesions exhibit distinct clinicopathological signatures characterized by rapid progression, aggressive anterior fossa and nasal region, and severe visual morbidity.…”
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Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis by Shumeng Ren, Yuhang Chen, Yu Liu, Qiuyi Lv, Jing Peng, Lei Song, Yihuai Zou, Hua Zhang, Xing Chen

“…ObjectiveThis meta-analysis aimed to evaluate the randomized controlled trials (RCTs) of acupuncture for somatosensory deficits after stroke to provide the current best evidence for clinical practice.MethodsA systematic search was performed for eligible articles on the acupuncture for somatosensory deficits after stroke based on 14 databases. …”
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Autologous leukocyte-poor platelet-rich plasma injection in the treatment of knee osteoarthritis: short-term clinical effect analysis by YANG Lei, JING Doudou, LIU Mingxi, GUO Zhenye, YANG Binai, LIN Shuzhong, ZHANG Demei, GUO Fengyan, LIU Jin

“…The degree and function of knee pain were assessed by visual analog scale(VAS) and knee arthritis index scale(WOMAC) at 1, 3 and 6 months after injection. …”
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Patient-Reported Outcomes Differentially Worsen in Patients With Greater Obesity Classes After Hip Arthroscopy by Gregory Perraut, M.D., Madison Thompson, B.A., Emily Krisanda, M.D., Seleem Elkadi, M.D., Shankar Thiru, B.A., Danny Chamaa, B.A., Evan Michaelson, M.D., William Postma, M.D.

“…Purpose: To explore the association between obesity classification and patient-reported outcomes (PROs) in hip arthroscopy. Methods: This retrospective cohort study included patients who underwent hip arthroscopy and completed at least 1 preoperative and corresponding postoperative PRO—the modified Harris Hip Score (mHHS), visual analog pain scale (VAS), or Veterans RAND 12 (VR-12)—between December 2018 and August 2023. …”
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Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural E... by Iza Ciglenecki, Nombuso Ntshalintshali, Esther Mukooza, Skinner Lekelem, Mpumelelo Mavimbela, Sindisiwe Dlamini, Lenhle Dube, Nomvuyo Mabuza, Melat Haile, Tom Ellman, Antonio Flores, Olivia Keiser, Sindy Matse, Roberto de laTour, Alexandra Calmy, Bernhard Kerschberger

“…We nested a diagnostic accuracy study within a larger study of the burden of sexually transmitted infections in rural Eswatini. Methods Adults were enrolled at six routine HIV testing sites (HTS) in the Shiselweni region between June 2022 and April 2023. …”
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A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy by Young-Hee Cho, Young-Hee Cho, Chi-Ah Chun, Chi-Ah Chun, Hector Ramos, Paul Buonora, Paul Buonora, Paul Buonora, Vasanthy Narayanaswami, Vasanthy Narayanaswami, Kim-Phuong L. Vu, Kim-Phuong L. Vu

“…Its second aim was to investigate whether applicants who were accepted to the programs using a holistic selection process differed in academic discipline, demographics, and psychosocial characteristics from applicants who were not accepted.MethodsInformation on students’ majors, race/ethnicity, and gender was obtained from the university records or applications submitted by students. …”
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Whole-body and site specific [18F]FDG uptake patterns on PET/CT have limited value in differentiating between polymyalgia rheumatica and other inflammatory diseases: two cohorts of... by Andreas Wiggers Nielsen, Gijs D. van Praagh, Kornelis S. M. van der Geest, Ib Tønder Hansen, Berit Dalsgaard Nielsen, Søren Geill Kjær, Jesper Blegvad-Nissen, Kate Rewers, Christian Møller Sørensen, Elisabeth Brouwer, Ellen-Margrethe Hauge, Lars Christian Gormsen, Riemer H. J. A. Slart, Kresten Krarup Keller

“…Results Patients with PMR were more likely than non-PMR patients to have bilateral [18F]FDG-uptake equal to or above liver compared at the ischial tuberosities (91%/41%), shoulder joints (86%/45%), hip joints (83%/52%), and along the lumbar spinal processes (70%/30%). …”
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Domestic violence and its determinants among reproductive-age women in Sub-saharan Africa: a multilevel analysis of 2019–2024 demographic and health survey data by Girum Nakie, Gebresilassie Tadesse, Setegn Fentahun, Gidey Rtbey, Fantahun Andualem, Getasew Kibralew, Mulualem Kelebie, Mamaru Melkam, Techilo Tinsae, Mulat Awoke Kassa, Tekletsadik Tekleslassie Alemayehu, Muluken Yigezu, Tigist Kifle Tsegaw, Tesfaye Segon, Yilkal Abebaw Wassie

“…It violates human rights, hinders gender equality, and requires a multifaceted approach. Studies in sub-Saharan Africa (SSA) reveal significant disparities across nations. …”
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Modifying exercise and physical therapy in medical rehabilitation to promote a physically active lifestyle: Protocol for a multicenter controlled hybrid type 2 effectiveness-implem... by Eva Grüne, Johannes Carl, Wolfgang Geidl, Johanna Popp, David Victor Fiedler, Natalie Boss, Regina Brinkmann, Juliane von dem Bussche, Gabi Eichner, Kathrin Kleinert, Christoph Löhr, Florian Mex, Paul Schwanitz von Keitz, Till Richter, Joachim Schmidt, Rainer Tischendorf, Gorden Sudeck, Klaus Pfeifer

“…The objectives of the STABEKO study are A) to evaluate the implementation of modified exercise and physical therapy and to identify influencing factors for development and implementation, and B) to determine the short- and long-term effectiveness of the modified therapy on PAHCO and physical activity of the persons undergoing rehabilitation. Methods As part of the STABEKO study, we will use cooperative planning as a co-creation approach for planning, developing, and implementing actions to modify exercise and physical therapy by engaging relevant actors from practice, policy, and research in an equal decision-making process. …”
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The Manitoba Personalized Lifestyle Research (TMPLR) study protocol: a multicentre bidirectional observational cohort study with administrative health record linkage investigating... by Navdeep Tangri, Dylan Mackay, Rebecca C Mollard, Matthew Granger, Sharon Bruce, Heather Blewett, Jared Carlberg, Todd Duhamel, Peter Eck, Patrick Faucher, Naomi C Hamm, Ehsan Khafipour, Diana McMillan, Semone Myrie, Amir Ravandi, Meghan Azad, Peter JH Jones

“…The objective of The Manitoba Personalized Lifestyle Research study is to understand how these lifestyle factors interact with each other and with other factors, such as an individual’s genetics and gut microbiome, to influence health.Methods An observational study of adults, with extensive phenotyping by objective health and lifestyle assessments, and retrospective assessment of early life experiences, with retrospective and prospective utilisation of secondary data from administrative health records.Study population A planned non-random convenience sample of 840 Manitobans aged 30–46 recruited from the general population, stratified by sex (equal men and women), body mass index (BMI; 60% of participants with a BMI>25 kg/m2) and geography (25% from rural areas). …”
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Phase II study of concomitant radiotherapy with atezolizumab in oligometastatic soft tissue sarcomas: STEREOSARC trial protocol by Nicolas Penel, Dominique Vaur, Juliette Thariat, Alexandre Escande, Jennifer le Guevelou, Colin Debaigt, Esma Saada-Bouzid, Julien Viotti, Nazim Khalladi, David Thibouw, Marie Pierre Sunyach, Laurence Moureau-Zabotto, Mohamed Benchalal, Ovidiu Veresezan, Anne Ducassou, Cecile le Pechoux, Maria Jolnerovski, Celine Bazille, Raphael Serre, Christine Lovera

“…In oligometastatic stage, stereotactic body radiation therapy (SBRT) allows reaching high control rates at treated sites (≥80%) and is potentially equally effective to surgery in term of overall survival. …”
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Obstacles for self-management practices among diabetes patients: A facility-based study from Coastal South India. [version 3; peer review: 2 approved] by Murali Mohan R, Rekha T, Balanarayana Suma, Nithin Kumar, Kausthubh Hegde, Bhaskaran Unnikrishnan, Prasanna Mithra, Ramesh Holla, Aysha Roushida Sahama M, Aadithya M Rao, Patil Nikitha

“…Background The management of diabetes mellitus (DM) extends beyond clinical care, with self-care being equally important to achieve optimal treatment outcomes and prevent complications. …”
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REMAP Periop: a randomised, embedded, multifactorial adaptive platform trial protocol for perioperative medicine to determine the optimal enhanced recovery pathway components in co... by Brian Williams, Jennifer Holder-Murray, Kathirvel Subramaniam, Kert Viele, Oscar C Marroquin, Scott Berry, Aman Mahajan, Luca La Colla, Charles Luke, Alison R Althans, Stephen A Esper, Joshua Knight, Joseph Derenzo, Ryan Ball, Shawn Beaman, Nicholas Schott, Elizabeth Lorenzi, Lindsay R Berry, Miranda Masters, Katie A Meister, Todd Wilkinson, William Garrard

“…Patients enrolled in the trial will be randomised to arms within both domains, with the possibility of adding additional domains in the future.Methods and analysis In the PONV domain, patients are randomised to optimal versus supraoptimal prophylactic regimens. …”
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The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss by Jessica Murphy, Jessica Murphy, Jessica Murphy, José A. Morais, José A. Morais, Michael A. Tsoukas, Alexandra B. Cooke, Stella S. Daskalopoulou, Stella S. Daskalopoulou, Stella S. Daskalopoulou, Sylvia Santosa, Sylvia Santosa, Sylvia Santosa

“…Weight loss can modify adipose tissue immune cell composition, but whether these changes differ by obesity onset remains unknown.MethodsWe compared abdominal and femoral subcutaneous adipose tissue (SAT) immune cell percentages between people with CO and AO before and after moderate (~10%) weight loss. …”
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Low-concentration atropine (0.01%) on quantitative contrast sensitivity function in Chinese children with myopia by Yu-Hao Ye, Yi-Yong Xian, Fang Liu, Zhong-Lin Lyu, Xing-Tao Zhou, Jing Zhao

“…AIM: To investigate the effect of 0.01% low-concentration atropine (LA) on quantitative contrast sensitivity function (qCSF) in children with myopia. METHODS: This paired case-control study included 90 eyes of 58 children who were sex-, age-, and refraction-matched and equally divided into two groups: the 0.01% LA group had undergone 6mo use of daily 0.01% atropine and control group was naïve to LA. …”
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