The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…Patients are randomised equally to receive two capsules of lansoprazole or two placebo capsules, two times per day for 12 months. …”
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Assessment of sub-maximal aerobic capacity in North African patients with chronic hepatitis B: a pilot case-control study [version 2; peer review: 2 approved] by Houda Chaouch, Imed Latiri, Jihene Bergaoui, Sawssen MRAD, Helmi Ben Saad, Samia Ernez Hajri, Jihene Ben Abdallah, Salma Amous

“…This study aimed to evaluate sub-maximal aerobic capacity in CHB patients compared to apparently healthy participants (control-group (CG)). Methods A 6-min walk test (6MWT) was performed. The 6-min walk distance (6MWD) was recorded, along with heart-rate (HR), oxy-hemoglobin saturation (SpO2), blood-pressure, and dyspnea ( ie ; visual analogue scale) at rest (Rest) and at the end (End) of the 6MWT. …”
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Scope of practice of primary care nurses: a protocol for an umbrella review of international literature by Kris Aubrey-Bassler, Marie-Ève Poitras, Shabnam Asghari, Michelle Swab, Lindsay Hedden, Maria Mathews, Ruth Martin-Misener, Elizabeth J Halcomb, Julia Lukewich, Leslie Meredith, Dana Ryan, Suzanne Braithwaite, Danielle Macdonald, Kathleen Leslie, Anaelle Morin, Monica McGraw, Patrick Chiu, Émilie Dufour, Sophia Myles, Annie Rioux-Dubois, Deanne Curnew, Jen Calver, Jill Bruneau

“…We will synthesise data from included studies in a detailed literature review table and develop visual aids to communicate the shared and unique roles and activities of PCN scope of practice. …”
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N-Glycoside of Indolo[2,3-<i>a</i>]pyrrolo[3,4-<i>c</i>]carbazole LCS1269 Exerts Anti-Glioblastoma Effects by G2 Cell Cycle Arrest and CDK1 Activity Modulation: Molecular Docking S... by Nikolay Kalitin, Natalia Koroleva, Anna Lushnikova, Maria Babaeva, Nadezhda Samoylenkova, Ekaterina Savchenko, Galina Smirnova, Yulia Borisova, Alexander Kostarev, Aida Karamysheva, Galina Pavlova

“…Mitotic figures were visualized by fluorescence microscopy. Quantitative RT-PCR was used to evaluate the gene expression. …”
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Gut microbiota-derived indoleacetic acid attenuates neuroinflammation and neurodegeneration in glaucoma through ahr/rage pathway by Ning Wang, Chengyang Sun, Yijie Yang, Dandan Zhang, Lulu Huang, Chenrui Xu, Minghan Wang, Mengmeng Xu, Tongtong Yan, Yue Wu, Li Xu, Yahan Ju, Hao Sun, Wenyi Guo

“…This study elucidates the neuroprotective role of gut microbiota derived tryptophan metabolites in glaucoma through gut-eye communication and inhibition of microglia-mediated neuroinflammation. Methods Gut microbiota profiling (16 S rRNA sequencing) and serum indoleacetic acid (IAA) quantification were performed in glaucoma patients versus controls. …”
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Meta-analysis of clinical trials of osteoarthritis treatment effectiveness with Chondroguard by I. Yu. Torshin, A. M. Lila, A. V. Naumov, A. Yu. Kochish, L. I. Alekseeva, E. A. Taskina, I. V. Sarvilina, A. N. Galustyan, A. N. Gromov, A. K. Khadzhidis, L. V. Vasilieva, E. F. Yevstratova, M. I. Udovika, O. A. Gromova

“…., EOD, course 20-30 injections) in the complex therapy of osteoarthritis (OA).Materials and Methods. Tie meta-analysis according to tie fixed-effects model included all published clinical studies on tie efficacy and safety of the CG drug in OA). …”
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Tailoring Chronic Disease Interventions to Meet Specific Needs of Women: A Case Example of a Hypertension Program by Caroline A. Dancu, Julie Schexnayder, Hayden B. Bosworth, Allison Lewinski, Abigail Shapiro, Tiera Lanford, Courtney White Clark, Bevanne Bean-Mayberry, Leah L. Zullig, Jennifer M. Gierisch, Karen M. Goldstein

“…This study describes a process for tailoring existing evidence-based interventions to the biological and sociocultural determinants of health for women. Methods: This study adapted the Team-supported, Electronic Health Record (EHR)-leveraged, Active Management (TEAM) CVD preventative care intervention designed for telehealth-based remote hypertension (HTN) care in rural Veterans. …”
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Performance on the Rey-Osterrieth complex figure test and the correlation with the magnetic resonance imaging brain lesion volume in multi-infract versus small vessel disease demen... by Semnić Marija D., Semnić Robert, Nikolašević Željka, Bugarski-Ignjatović Vojislava V., Vujanić-Stankov Tijana Ž., Kostić Smiljana, Ocić Gordana, Kozić Duško

“…The importance of visuospatial, visuoconstructional deficit and impairment of visual memory is disregarded in VaD subtypes. These impairments are more severe in MID than SSVD and the deficit of ROCF copying in MID patients correlates with posterior and total MRI lesion volume.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi, Dalia Ali, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez

“…Alkaline phosphatase (ALP) activity and formation of mineralized matrix visualized by Alizarin red staining were employed as markers for osteoblastic differentiation. …”
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A bibliometric analysis of exosomes in aging from 2007 to 2023 by Zenghui Niu, Meiyu Cui, Yingkun Fu, Lingfeng Zhou, Jiali Wang, Jiali Wang, Yan Lei, Xinrong Fan, Qiang Wang, Jing Yang

“…Thery C proposed the method of differential centrifugation and density gradient centrifugation to extract exosomes. …”
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Feeding challenges in early infancy: the role of reflexes, muscle tone, and developmental milestones by Wiktoria Kowalska, Maria Tuczyńska, Jacek Kwiatkowski, Oskar Komisarek, Ewa Mojs, Mirosław Andrusiewicz, Tomasz Szczapa, Włodzimierz Samborski, Dorota Sikorska, Ewa Baum, Roksana Malak

“…The infants’ reflexes were checked, the muscle tone was palpated, the presence of general movements was visually assessed using Prechtl’s method, then the Sensitivity Assessment of the Stomatognathic Complex (SOWKUT) questionnaire and Albert Infant Motor Scale (AIMS) scale were evaluated. …”
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Artificial intelligence-produced radiographic enhancements in dental clinical care: provider and patient perspectives by Lyubov D. Slashcheva, Lyubov D. Slashcheva, Kelly Schroeder, Lisa J. Heaton, Hannah J. Cheung, Brenda Prosa, Nicole Ferrian, Jesse Grantz, Jesse Grantz, Deborah Jacobi, John J. O’Malley, Michael Helgeson, Eric P. Tranby

“…The goal of this study was to survey dental providers and patients about the use of AI-enhanced radiographs in the diagnostic and patient education processes.MethodsWithin their Community Collaborative Practice model, Apple Tree Dental in Minnesota implemented the use of an AI software platform that annotates carious lesions and periodontal measurements on dental radiographs. …”
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The critical role of diet, exercise, and sleep in shaping the gut microbiota of children with idiopathic short stature: a Retrospective study by Qin Zeng, Qin Zeng, Jun Zhu, Jun Zhu, Yanling Hu, Yanling Hu, Shaoyu Su, Shaoyu Su, Jing Chen, Jing Chen

“…ObjectivesTo investigate the gut microbiota in children with varying degrees of idiopathic short stature (ISS) and to examine the relationship between their intestinal microbiota and lifestyle factors, including diet, exercise, medication, sleep, and psychological state.MethodsA retrospective study involving 58 ISS children was conducted from May to October 2022. …”
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Enhancing safety with an AI-empowered assessment and monitoring system for BSL-3 facilities by Yi-Ling Fan, Ching-Han Hsu, Ju-Yu Wu, Ying-Ying Tsai, Wei J. Chen, Min-Shi Lee, Fang-Rong Hsu, Lun-De Liao

“…The identification results were presented in real time via a visual interface and simultaneously stored on the administrator's dashboard for future reference. …”
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Dilatation of the main pulmonary artery in patients with isolated pulmonary stenosis: Arteriopathy or hemodynamic consequence? by Pietro Paolo Tamborrino, Michela Miglianti, Dario Freitas, Camelia Demetrescu, Christopher Rush, Claudia Montanaro, Alessandra Frigiola

“…The aim of our study was to detect the incidence of mPA dilatation and aneurysm in patients with isolated PV stenosis and the association with PV function. Methods: In this single-center retrospective observational study, all patients with a diagnosis of isolated PV stenosis referred to our center were enrolled. …”
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Change in choroid thickness and vascularity index associated with accommodation and aberration after small-incision lenticule extraction by Dan Cheng, Yi-Lin Qiao, Xue-Ying Zhu, Kai-Ming Ruan, Heng-Li Lian, Mei-Xiao Shen, Shu-Lin Wang, Li-Jun Shen, Yu-Feng Ye

“…Choroid parameters on SS-OCT varies in eyes with different refractive errors after SMILE and has an association with accommodation and visual quality.…”
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Acetyl-L-Carnitine as an Add-On Treatment in Fibromyalgia Syndrome: A Retrospective Analysis on 183 Patients, According to the Generalized Linear Mixed Model for Longitudinal Data by Vittorio Schweiger, Libera Villagrossi, Francesco Taus, Leonardo Gottin, Eleonora Bonora, Marco Anderloni, Giustino Varrassi, Luca Polati, Marta Nizzero, Alvise Martini, Enrico Polati

“…Regarding efficacy, in the 137 analyzed patients, the change from baseline to the end of observation in Visual Analogue Scale score (VAS) was statistically significant, ranging from 75.9 ± 1.56 to 51.9 ± 1.99 (<i>p</i> < 0.001). …”
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Lack of pre-movement facilitation as neurophysiological hallmark of fatigue in patients with Parkinson's disease: A single pulse TMS study by Antimo Buonocore, Celeste Cafaro, Ciro De Luca, Giovanna Vermiglio, Giovanna Sepe, Giuseppe Rocco, Marco Aiello, Andrea Soricelli, Michele Papa, Carlo Cavaliere, Giovanni Cirillo

“…Participants performed a reaction time (RT) task involving thumb abduction following a visual go signal, while transcranial magnetic stimulation (TMS) was applied over the primary motor cortex (M1) at intervals of 50, 100, and 150 ms before movement onset. …”
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Utilization of magnification devices in Vietnam’s dental practice and education: an online survey by Minh-Hieu Nguyen Tran, Anh Huynh Bui, Lan-Anh Hoang Le, Thuy-Trang Thi Huynh, Phuong-Doan Phan, Thuan-Loc Tran, Nguyen-Tra-Mi Le, Thu-Tra Nguyen, Hoang-Vinh Le, Dai-Phong Lam, Quoc-Viet Lam, Tran-Lan-Khue Pham, An-Tran Pham, Van-Khoa Pham

“…Dental loupes, conventional dental operating microscopes (DOMs), and three-dimensional digital operating microscopes (3D-DOMs) help overcome visual limitations in intricate procedures. Although widely used globally, adoption in Vietnam remains underreported. …”
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Levels of physical activity in a large international cohort of patients with systemic lupus erythematosus by Laurent Arnaud, Matteo Piga, Manuel Francisco Ugarte-Gil, Christelle Sordet, Philippe Mertz, Luc Pijnenburg, Marina Rinagel, Lou Kawka, Sophie Geneton, Julien Blaess, Timothée Mischler, Juan C Sarmiento-Monroy

“…The aim of this study was to assess PA level and characteristics in a large international cohort of patients with SLE.Methods PA was assessed in metabolic equivalent of tasks (METs) using the International Physical Activity Questionnaire (IPAQ) and classified into three levels: low, moderate and high PA. …”
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