Comparative efficacy and safety of nitinol vs. novel fully biodegradable occluders for transcatheter patent foramen ovale closure in migraine treatment: a retrospective cohort stud... by Rui-lin Li, Jing-juan Huang, Jie Ming, Ying Hao, Wei Wen, Yun-li Shen, Li Lin, Lin-xiang Lu

“…Residual right-to-left shunting was minimal in both groups, with RLS grades 0 and 1 observed in 82.35% of patients in the nitinol group and 78.87% in the bioabsorbable group at the 12-month follow-up.ConclusionBoth biodegradable and nitinol PFO occluders were equally effective in alleviating migraine symptoms, with excellent procedural success and safety profiles. …”
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Distribution characteristics, source apportionment, and health risk assessment of metals and metalloids in PM2.5 in a southern city in 2019 by Yaxin QU, Suli HUANG, Chao WANG, Jie JIANG, Jiajia JI, Daokui FANG, Shaohua XIE, Xiaoheng LI, Ning LIU

“…ObjectiveTo assess the distribution characteristics of metals and metalloids in outdoor PM2.5 in a southern city of China, conduct source apportionment, and evaluate the associated health risks, thereby providing theoretical support for further pollution control measures. MethodsPM2.5 samples were collected in districts A, B, and C of a southern China city, and the concentrations of 17 metals and metalloids were detected by inductively coupled plasma-mass spectrometry (ICP-MS). …”
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Association between serum albumin and severe impairment of activities of daily living in patients with stroke: a cross-sectional study by Ranran Bi, Yupeng Shi, Manrong Li, Xiaochen Liu, Zhenchao Ma, Yiqing Huang, Bingyin Liang, Fang Cui

“…This study aims to provide further results.Materials and methodsThis study examined cross-sectional data from patients aged 18 years or older with a diagnosis of stroke confirmed by cranial CT or MRI within 24 h of admission, gathered from January 2020 to August 2022. …”
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Effect of Telemedicine-Supported Structured Exercise Program in Patients with Chronic Low Back Pain: Study Protocol for a Randomized Controlled Trial by Feng Y, Jia C, Liu H, Bao T, Wang C, Wang Z, Huang J, Jiang Y, Wang X, Zhang R, Zhang Y, Zhang S, Zhu S, He C

“…Consequently, further research is warranted to clarify the impact of telemedicine-supported structured exercise programs on patients with CLBP.Patients and Methods: This randomized controlled trial will include patients with CLBP who have not received exercise therapy in the past three months. …”
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Human Neural Stem Cells Reduce Hypoxia-Ischemic Neurological Impairment Through the Regulation of Inflammatory M1/M2 Microglias in Rats by Ding YB, Zhao Y, Chen BY, Wang Q, Wang ZY, Luan Z, Yi B

“…Ya-Bing Ding,1,2,* Yuan Zhao,1– 3,* Bing-Yu Chen,1 Qian Wang,1 Zhao-Yan Wang,1 Zuo Luan,1,2 Bin Yi4 1Department of Pediatrics, The Sixth Medical Center of PLA General Hospital, Beijing, People’s Republic of China; 2Department of Pediatrics, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, People’s Republic of China; 3Department of Neonatology, Children’s Hospital of Shanxi, Women Health Centre of Shanxi, Taiyuan, People’s Republic of China; 4Department of Pediatrics, Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zuo Luan, Department of Peadiatric, The Sixth Medical Center of PLA General Hospital, Beijing, 100048, People’s Republic of China, Tel +86-18600310270, Fax +86-1066958303, Email luanzuodoctor@126.com Bin Yi, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, 730000, People’s Republic of China, Email www.0931@163.comObjective: This study aims to investigate the therapeutic efficacy and migration of human neural stem cell (hNSC) therapy in a rat model of moderate to severe Hypoxic-ischemic encephalopathy (HIE).Methods: hNSCs were transplanted into the brain ventricle of HIE-induced rats. …”
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Protective Effects of Gynostemma pentaphyllum Saponins on Liver Injury in Guinea Pigs of Hyperlipemia Based on Oxidative Stress by Tianyi DAI, Donglian LIU, Xingmin QIN, Chengling GAO, Jiayi LI, Hailing KUANG

“…The normal group and model group were given equal amount of normal saline. The body mass, body length, and Lee's index of each group of guinea pigs were measured weekly. …”
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The Mechanism of Sijunzi Decoction Suppresses Gastric Cancer Metastasis via the m6A Methyltransferase METTL14 Based on Untargeted Metabolomics Studies and Network Pharmacology Anal... by Li X, Zhao L, Wang J, Ma T, Zhou J, Bian Y, Guo J

“…However, additional research is necessary to comprehend the mechanisms beneath the therapeutic potential of SJZ in gastric cancer.Objective: This research endeavored to analyze how SJZ treats gastric cancer using network pharmacology and experimental validation.Methods: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and network pharmacology were applied to systemically clarify the mechanism of SJZ against gastric cancer. …”
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Aggregation of Stress Granules Induced by Hypoxia and Lipopolysaccharide via PKR-p-eIF2α Pathway and 4EBP1 Pathway Inhibits the Inflammatory Response in Peri-Implantitis by Li S, Ma C, Fan C, Liu Y, Li J, Yin B, Zhong L, Bai N, Li Z

“…Shuang Li,1,2,* Chunling Ma,3,* Chun Fan,4 Yanshan Liu,5 Jian Li,2,6 Baoheng Yin,1,2 Lingmei Zhong,7 Na Bai,1,2 Zhiyuan Li3 1Department of Prosthodontics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 2School of Stomatology, Qingdao University, Qingdao, Shandong, People’s Republic of China; 3Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 4Department of Periodontology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 5Department of Maxillofacial Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 6Department of Oral Implantology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 7Department of Pulmonary and Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiyuan Li, Email zyli0120@163.com Na Bai, Email na.bai@qdu.edu.cnObjective: To investigate whether stress granules (SGs) exist in peri-implantitis (PI) and to explore the formation mechanism and role of SGs in the response of human gingival fibroblasts (hGFs) to hypoxia or LPS.Methods: Gingival tissues were collected from patients with PI and from healthy individuals. …”
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Growth Differentiation Factor-15 as a Potential Biomarker for Renal Involvement in POEMS Syndrome by Huang Y, Chen J, Yao Y, Zhang L, Li Y, Li J

“…Growth differentiation factor-15 (GDF-15) is related with renal function, but few studies have focused on it in renal impairment of POEMS syndrome.Objective: To evaluate the potential of circulating GDF-15 concentration as a biomarker for renal function in POEMS syndrome.Methods: 150 Chinese patients, diagnosed with POMES syndrome, were enrolled and divided into three subgroups according to their chemotherapy stage. …”
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Development and Validation of Predictive Models for Inflammatory Bowel Disease Diagnosis: A Machine Learning and Nomogram-Based Approach by Dong R, Wang Y, Yao H, Chen T, Zhou Q, Zhao B, Xu J

“…This study aimed to develop predictive models for diagnosing IBD, Crohn’s disease (CD), and Ulcerative colitis (UC) by combining two approaches: machine learning (ML) and traditional nomogram models.Methods:  Cohorts 1 and 2 comprised data from the UK Biobank (UKB), and the First Hospital of Jilin University, respectively, which represented the initial laboratory tests upon admission for 1135 and 237 CD patients, 2192 and 326 UC patients, and 1798 and 298 non-IBD patients. …”
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Assessment of The Factors Affecting Management of Gender and Sexual Violence Against Women in Rural Communities: A Case Study of Kyanamira Sub County Kabale District. by Tumuheki, Timothy

“…The researcher employed a content analysis method to analyze the data. The emerging themes and opinions were properly analyzed, and compared with the information that was obtained in the literature review. …”
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Optical and electron microscopy imaging of model circulating tumour cells by Марина Оленчук, Григорій Монастирський, Олена Гнатюк, А. Бойзен, Ч. Чжан, Галина Солянік, Денис Колесник, Сергій Карахім, Галина Довбешко

“…Background: Microscopy is a key tool in biophysical research for visualizing living cells' morphology, structure, and dynamic processes. …”
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Intravitreal Dexamethasone Implant for Postoperative Macular Oedema Secondary to Vitrectomy for Epiretinal Membrane and Retinal Detachment: A Systematic Review and Meta-Analysis by Guglielmo Parisi, Matteo Fallico, Teresio Avitabile, Antonio Longo, Elina Ortisi, Andrea Russo, Francesco Petrillo, Andrea Maugeri, Martina Barchitta, Vincenza Bonfiglio, Claudio Furino, Gilda Cennamo, Paolo Caselgrandi, Paola Marolo, Luca Ventre, Michele Reibaldi

“…The primary outcome was best-corrected visual acuity (BCVA) change between baseline and post-DEX treatment, reported as mean difference (MD) with 95% confidence interval (CI). …”
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Development of a predictive model for long-term care and support eligibility certification associated with dementia-related functional impairments: the IRIDE cohort study by Daichi Yamashiro, Hiroyuki Suzuki, Susumu Ogawa, Mari Yamashita, Hiroki Moriya, Hiroyuki Sasai, Shuichi P. Obuchi, Takumi Abe, Hiroshi Murayama, Takumi Hirata, Yoshinori Fujiwara, Shuichi Awata, Masahiro Akishita, Kenji Toba, IRIDE Cohort Study Investigators

“…Model 2, which included six predictors (age, history of stroke, history of heart disease, visual impairment, hearing impairment, and exercise habits), achieved a C-index of 0.73 (95% CI: 0.70–0.75) in the derivation dataset and 0.77 (95% CI: 0.73–0.81) in the validation dataset. …”
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Effects of proprioceptive exercise for knee osteoarthritis: a systematic review and meta-analysis by Yaoyu Lin, Debiao Yu, Debiao Yu, Debiao Yu, Xiaoting Chen, Peng Chen, Nan Chen, Bin Shao, Bin Shao, Bin Shao, Bin Shao, Qiuxiang Lin, Qiuxiang Lin, Fuchun Wu, Fuchun Wu, Fuchun Wu, Fuchun Wu

“…The present study sought to systematically evaluate the effects of proprioceptive exercise on symptoms and functional outcomes in patients with KOA, with a particular focus on balance performance.MethodsFollowing PRISMA guidelines, a comprehensive search was conducted across six electronic databases from the establishment of the database to January 21, 2025. …”
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Short-Term Effects of a Snack Including Fruit Juice Enriched with Vitamin D3, n-3 Fatty Acids, and Probiotics on Energy Intake and Satiety in Normal-Weight and Overweight Individua... by Christina Athanasaki, Nikolaos Zacharodimos, Sofia Tsitsou, Dionysia-Lydia Bothou, Stamatia Vitsou-Anastasiou, Olga S. Papadopoulou, Emilia Papakonstantinou

“…The participants rated their hunger, desire to eat, perceived fullness, thirst, preoccupation with food, and pleasure of eating on visual analogue scales (VAS) at the baseline and at 15–30 min intervals up to 7 h of the intervention. …”
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Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a... by Tingting Jiang, Zailin Yang, Xinyi Tang, Xinyi Tang, Na Fan, Zuhai Hu, Jieping Li, Tingting Liu, Yu Peng, Shuang Chen, Bingling Guo, Xiaomei Zhang, Yong Chen, Jun Li, Dehong Huang, Jun Liu, Yakun Zhang, Yakun Zhang, Xuefen Liu, Xia Wei, Zhanshu Liu, Haike Lei, Yao Liu

“…This study aimed to develop a machine learning-based early warning system (VTE-EWS) tailored to these patients.MethodsData from 1,141 lymphoma patients hospitalized for chemotherapy were retrospectively collected across four academic medical centers between February 2020 and February 2024. …”
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High-Grade Pneumonitis Events in Patients With Unresectable, Locally Advanced NSCLC Treated With Definitive Chemoradiation Followed by Adjuvant Durvalumab by Ciani Ellison, MD, Michael Martens, PhD, Juliana Alvarez Argote, MD, Samantha Benz, MD, Adam Currey, MD, Candice Johnstone, MD, MPH, Slade Klawikowski, PhD, Katie Livingston, MD, John M. Longo, MD, Smitha Menon, MD, Saryleine Ortiz de Choudens, MD, Lindsay Puckett, MD, Janet Retseck, MD, PhD, Monica Shukla, MD, Jonathan Thompson, MS, MD, Elizabeth Gore, MD, FACR

“…Objective: To review the incidence of pneumonitis and contributing factors, and also to review grade 5 pneumonitis (G5) events. Methods: We identified 78 cases with a median age of 70.0 years and a median follow-up of 36 months. …”
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Roxadustat promotes allograft recovery after kidney transplantation: A prospective, multicenter, randomized controlled trial by Mao-Lin Ma, Fei Han, Lei Zhang, Zheng-Yu Huang, Tao Zhang, Heng Li, Jia-Li Fang, Zheng Chen, Ning Na

“…The patients were randomly and equally divided into two groups. One group received oral roxadustat (Roxadustat group), while the other group received subcutaneously injected epoetin alfa (Erythropoietin group). …”
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Physical and Mechanical Properties of Ti-Zr-Nb Alloys for Medical Use by Konstantin V. Sergienko, Sergei V. Konushkin, Mikhail A. Kaplan, Artem D. Gorbenko, Yucheng Guo, Elena O. Nasakina, Maria A. Sudarchikova, Tatiana M. Sevostyanova, Yaroslava A. Morozova, Lyudmila A. Shatova, Sofia A. Mikhlik, Mikhail A. Sevostyanov, Alexey G. Kolmakov

“…Homogenizing annealing in a vacuum furnace at 1000 °C for 4 h was used to equalize the composition. The structure of the alloyed sheets after hot rolling and hot rolling and quenching was investigated. …”
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