The Sensitive Genes for Cervical Cancer: Two-Sample Mendelian Randomization with Experimental Validation by Zhang R, Chai S, Chen Q, Lai J, Cai C

“…This study seeks to identify novel therapeutic targets to address this urgent clinical need.Methods: Our team identified differentially expressed genes (DEGs) in cervical cancer using gene expression omnibus (GEO) datasets. …”
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Cytokine Signatures as Biomarkers of Clinical Remission in Rheumatoid Arthritis by Su W, Xiao Y, Chen X, Wu Y, Wu B, Yang Q, Peng B, Tang J, Yang Y

“…This study aimed to investigate the potential of intricate cytokine networks for predicting the clinical remission of RA.Methods: In total, 164 patients with RA and 69 healthy individuals were included in this study. …”
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La Medicina Tradicional y Natural en el tratamiento de la estomatitis subprótesis by Ivonne Guerrero Ricardo, Yosvany Ramón Armas Pupo, Digna Norma Arévalo Rodríguez, Madelín Machado Coayo

“…Objective: to describe the application of the traditional natural medicine in the treatment of the subprosthesis stomatitis. Methods: a deep review about last year from January 2012 to September 2012 was done. …”
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Effect of Entecavir, Tenofovir Disoproxil Fumarate, and Tenofovir Alafenamideantiviral Therapy on Renal Function in Chronic Hepatitis B Patients: A Real-World Retrospective Study by Li Y, Li YW, Gao Y

“…This study aimed to assess the renal safety profile in NUC-experienced CHB patients who received ETV, TDF or TAF therapy.Methods: This retrospective observational cohort study investigated factors related to renal function in 154 patients with NUC-experienced CHB who received ETV, TDF, and TAF therapy for 48 weeks. …”
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Gui-Pi-Tang Defers Skeletal Muscle and Cardiac Muscle Aging by Promoting Mitochondrial Remodeling by Cai C, Wang M, Yang D, Jing C, Li Y, Xu H, Liu F, Zhao D

“…Changjiu Cai,1,* Manying Wang,2,* Dan Yang,2 Chenxu Jing,2 Yingna Li,3 Hanying Xu,4 Fangbing Liu,5 Daqing Zhao5 1Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 2Research Center of Traditional Chinese Medicine, Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 3College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 4Department of Encephalopathy, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 5Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fangbing Liu, Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China, Email liufb@ccucm.edu.cn Daqing Zhao, Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China, Email zhaodaqing1963@163.comPurpose: To determine whether Gui-Pi-Tang (GPT) has protective effects on skeletal muscle and cardiac muscle in aged mice.Methods: This study used C57BL6/J mice to establish an in vivo natural aging model, while D-galactose (D-gal)-injured C2C12 and H9c2 cells were employed to create in vitro aging cell models. …”
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Screening and Verification COPD-OSA Overlap Syndrome Core Genes Using Bioinformatics by Qiang S, Wan R, Wu J, Wang C, Cui X, Zhang Y

“…To address this, we explored potential OS mechanisms using bioinformatics.Methods: OSA and COPD gene expression datasets were obtained from the Gene Expression Omnibus (GEO) database. …”
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One‐stage spatial mark–resight analysis reveals an increasing grizzly bear population with declining density near roads by Jesse Whittington, Mark Hebblewhite, Connor Meyer, Barb Johnston, Anne Forshner, Bryan J. Macbeth, Anthony L. Einfeldt, Seth G. Cherry

“…Both methods had >95% credible interval coverage and minimal bias. …”
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Effect of Lamotrigine on Refractory Epilepsy: Clinical Outcomes and EEG Changes by Li Z, Wu P, Chen Q, Tong X, Yang Q

“…., Internal Medicine, Shijiazhuang, 050000, People’s Republic of China; 2Department of Neurology, Baoding First Central Hospital, Baoding, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Li, Email lizheng741789@163.comBackground: Refractory epilepsy poses significant challenges in clinical management due to its resistance to standard antiepileptic therapies, necessitating the exploration of more effective treatment regimens. …”
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Knowledge, Attitudes, and Practices Among Patients Undergoing Gastrointestinal Endoscopy in the Endoscopy Unit of a Tertiary-Care Hospital by Wei L, Niu Q, Ma L, Liu G, Zhang H, Zheng X, Lin Y, Du N, Li L

“…Our objective was to assess the KAP regarding gastrointestinal endoscopy in the Endoscopy Unit among those referred for diagnostic procedures.Patients and Methods: Patients scheduled for gastrointestinal endoscopy completed self-administered questionnaires to gather demographic information and evaluate their KAP scores. …”
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Contribution of Interleukin-1 Receptor-Associated Kinase 1 Gene Polymorphism to Systemic Lupus Erythematosus in Chinese Patients by Zhao L, Xu W, Du S, Xi F, Shi X, Liu R

“…The aim of the current study was to analyze the association between the IRAK1 polymorphisms (rs3027898 and rs1059702) and SLE in a Chinese cohort.Patients and Methods: A total of 150 SLE patients and 168 healthy controls of Chinese ethnicity were included in this study. …”
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Effects of Preoperative Magnesium Sulphate Infusion on Emergence Agitation and Postoperative Quality of Recovery in Patients Undergoing Thoracoscopic Lobectomy by Pu Y, Geng X, Wang M, Lv G, Hu Z, Fang C, Zhang X, Li W, Fan X, Chen X

“…This study aimed to examine the effects of preoperative magnesium sulphate infusion on emergence agitation and postoperative quality of recovery in patients undergoing thoracoscopic lobectomy.Patients and Methods: 84 patients undergoing thoracoscopic lobectomy were randomly assigned to either the magnesium sulphate group (group M) or the control group (group C). …”
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A Machine Learning Model for Predicting Prognosis in HCC Patients With Diabetes After TACE by Wu L, Chen L, Zhang L, Liu Y, Ouyang D, Wu W, Lei Y, Han P, Zhao H, Zheng C

“…Lastly, the SHapley Additive exPlanations (SHAP) method was used to interpret the final ML model.Results: A total of 636 patients were included. …”
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IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery by Cheng H, Ma J, Zhao F, Liu Y, Wu J, Wu T, Li H, Zhang B, Liu H, Fu J, He H, Zhu C, Ren H, Yang C, Qin S

“…Hao Cheng,1,* Jiao Ma,1,* Fengyu Zhao,2 Yiwei Liu,3 Jie Wu,4 Tao Wu,1 Hui Li,1 Boxiang Zhang,3 Hui Liu,5 Junke Fu,3 Haiqi He,3 Cailin Zhu,3 Hong Ren,3 Chengcheng Yang,2 Sida Qin3 1Department of Rehabilitation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 3Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 4Department of Radiation Oncology, Shaanxi Provincial People’s Hospital, Xi’an, Shaanxi, People’s Republic of China; 5Biobank, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Sida Qin, Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, 277 West Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China, Tel +86 15388666585, Email qinsida@xjtu.edu.cn Chengcheng Yang, Department of Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, 277 West Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China, Tel +86 17629260656, Email ccyang@xjtufh.edu.cnObjective: This research sought to assess the predictive potential of the inflammation-immunity-nutrition score (IINS) and the high-sensitivity C-reactive protein-albumin-lymphocyte (CALLY) index in individuals with NSCLC post-surgery.Methods: The study enrolled 506 patients with NSCLC undergoing R0 resection at the First Affiliated Hospital of Xi’an Jiaotong University. …”
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EC50 and EC95 of Remifentanil for Inhibiting Bronchoscopy Responses in Elderly Patients During Fiberoptic Bronchoscopy Under Ciprofol Sedation: An Up-and-Down Sequential Allocation... by Lan H, Liu S, Liao Y, Xu B, Lin Y, Wu X, Chen Q, Chen H, Guan X

“…The EC50 and EC95 values of remifentanil required to alleviate the responses to FOB were calculated using Dixon’s up-and-down method for both male and female groups. Probit analysis was used to generate a dose-response curve.Results: Thirty-nine patients (19 males and 20 females) were enrolled. …”
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Effects of Short Naps on EEG Microstates: Improving Sleep Deprivation-Induced Cognitive Impairment by Ma C, Peng J, Li Y, Ouyang A, Huang Y, He W, Zhu Y, Fang P

“…This study aims to explore the effects of napping on cognitive impairments cause by SD and the potential mechanisms of cognitive recovery.Patients and Methods: We recruited forty-two healthy volunteers and recorded their EEG signals and psychomotor vigilance task (PVT) data at three time points: rested wakefulness, post-SD, and post-nap. …”
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Genetic Insights Into Lipid Traits and Lipid-Modifying Drug Targets in Pregnancy Complications: A Two-Sample Mendelian Randomization Study by Shao H, Xu C, Zhang C, Li L, Wu P, Chen Z, Guan R

“…This two-sample Mendelian Randomization (MR) study investigated the causal relationship between lipid traits and pregnancy complications and evaluated the impact of lipid-modifying drug targets.Methods: Genetic instruments for lipid traits and targets for lipid-modifying drugs were obtained from the Global Lipids Genetics Consortium. …”
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Exploring the Role of Allergenic Components in Children with House Dust Mite-Induced Allergic Diseases by Xu Q, Shang Y, Li X, Ran S, Lu M, Cheng L

“…Qiuyan Xu,1,* Yunxia Shang,1,* Xiang Li,1 Shuangqin Ran,1 Min Lu,1 Lei Cheng2,3 1Department of Pediatrics, Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou, People’s Republic of China; 2Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 3International Centre for Allergy Research, Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Cheng, Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People’s Republic of China, Email chenglei@jsph.org.cn Min Lu, Department of Pediatrics, Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, 1 Lijiang Road, Suzhou, 215153, People’s Republic of China, Email samy_lm@163.comPurpose: To investigate the main characteristics of HDM-induced allergic diseases in children and to explore allergen component-specific sensitization patterns, features, and correlations with clinical symptoms.Methods: Serum samples were collected from children with HDM-induced allergic diseases. …”
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Dynamic Changes in ALFF and DC in Subthreshold Depression Before and After ICBT Intervention by Wang Y, Ying Y, Zhu Z, Wang L, Yang Y, Zhang L, Yu W, Liang Y, Zhang H, Ji Y, Pan Y

“…This study aimed to examine changes in intrinsic brain activity in SD and their further alterations after ICBT intervention.Patients and Methods: Twenty-five individuals with SD and 25 matched healthy controls (HC) were enrolled. …”
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Automatic Real-Time Detection and Diagnosis of Liver Tumor with Ultrasound by Wu CH, Sheu JC, Chou PL, Lee J, Nien HC

“…We aimed to develop deep learning (DL) models to automatically diagnose and detect hepatic lesions in a larger dataset, with HCC as the dominant malignancy.Methods: We enrolled patients diagnosed with hepatic tumors using abdominal ultrasound between January 2002 and December 2020 in a retrospective cohort with a diagnosis of malignant and benign lesions. …”
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IL-6/IL-6R Signaling Blockade Alleviates Chronic Allograft Rejection by Modulating Germinal Center B Cells and Allograft Inflammation in Murine Cardiac Transplantation by Xia R, Shi X, Zhang H, Zeng W, Yang Z, Xu J, Wang J, Miao Y, Liao T

“…In this study, we investigate the preventive efficacy and underlying mechanism of IL-6/IL-6R signaling blockade.Methods: The CR model in mice was constructed using allogeneic cardiac transplantation with CTLA4-Ig injection. …”
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