Neoadjuvant chemoradiation and surgical excision versus definitive radiotherapy for locally advanced cervix uteri carcinoma: in terms of early and late complications and locoregion... by Hisham Khalifa, Mohamed Ayaty, Reham Oreaba, Reem Emad, Mohamed Salama, khaled Elsebahy, Wael A. Wahab Ghoniem

“…Depending on the major treatment technique, 120 FIGO stage IB3–FIGO stage IVA cervical cancer patients were split into two equal groups of 60 patients each. Sixty patients (50%) received neo-adjuvant EBRT and concurrent platinum-based chemotherapy followed by hysterectomy (group A) and 60 (50%) received definitive radiotherapy only (group B). …”
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Association Between Metabolic Syndrome and Cardiac Autonomic Nervous Function and Cardiorespiratory Fitness in Older Adults: A Retrospective Observational Study with Propensity Sco... by Cui N, Li Q, Cheng J, Xing T, Shi P, Wang Y, Luo M, Dun Y, Liu S

“…The present study aimed to investigate the association between MetS and HRRs at 1, 2, 3 and 6 minutes after exercise and cardiorespiratory fitness (CRF) in Chinese dwelling older adults.Methods: This retrospective, observational study consecutively enrolled participants aged 60 years or older who underwent physical examinations in Shenzhen District Yantian People’s Hospital from September 2019 to July 2021. …”
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Increased Risk of Dermatomyositis in Patients with Psoriasis: A Retrospective Cohort Study by Chen M, Tian N, Cui R, Zhang H, Wang Q, Tong Q, Chen Z, Wang YH, Wei JC, Dai SM

“…Miao Chen,1,* Na Tian,1,* Ran Cui,1 Hua Zhang,1 Qian Wang,1 Qiang Tong,1 Zhiyong Chen,1 Yu-Hsun Wang,2 James Cheng-Chung Wei,3– 6,* Sheng-Ming Dai1,* 1Department of Rheumatology and Immunology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan; 3Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, People’s Republic of China; 4Department of Allergy, Immunology & Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan; 5Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; 6Institute of Medicine/Department of Nursing, Chung Shan Medical University, Taichung, Taiwan*These authors contributed equally to this workCorrespondence: Sheng-Ming Dai, Department of Rheumatology and Immunology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China, Email shengmingdai@163.com James Cheng-Chung Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, Email jccwei@gmail.comPurpose: This study aimed to investigate the risk of dermatomyositis among patients with psoriasis in a large population.Patients and Methods: Individuals aged ≥ 20 years with records in the TriNetX database from January 1, 2002 to December 31, 2022 were included. …”
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Burden of Carbon Monoxide Poisoning in Asian Countries From 1990 to 2021 and Its Projection Until 2030: An Analysis of the Global Burden of Disease Study 2021 by Xie J, Wu C, Zhao Z, Cao Z, Jin X

“…This study seeks to assess the burden of CO poisoning in Asia from 1990 to 2021 utilizing data from the Global Burden of Disease Study (GBD) 2021.Methods: Data on the burden of CO poisoning across 49 Asian countries were extracted from GBD 2021. …”
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Efficacy of a Web-Based Stress Management Intervention for Beginning Teachers on Reducing Stress and Mechanisms of Change: Randomized Controlled Trial by Hanna Heckendorf, Dirk Lehr

“…Findings from the mediation analysis suggest that both problem-focused and emotion-focused coping strategies should be equally considered in stress management interventions. …”
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Determinants of Healthcare Professionals’ Knowledge on Age-Related Macular Degeneration Risk Factors in Ethiopia by Alemu DS, Munaw MB, Bekele MM, Asmare Kindie C, Ayele FA, Limenih MA

“…Destaye Shiferaw Alemu,1,* Minychil Bantihun Munaw,2 Matiyas Mamo Bekele,2 Chalie Asmare Kindie,3 Fisseha Admassu Ayele,3 Miteku Andualem Limenih1,* 1Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia; 2Department of Optometry, School of Medicine, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia; 3Department of Ophthalmology, School of Medicine, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia*These authors contributed equally to this workCorrespondence: Destaye Shiferaw Alemu, Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.O.Box: 196, Gondar, Ethiopia, Tel +251938316951, Email destayest@gmail.comPurpose: The aim of this study was to assess knowledge of healthcare professionals on risk factors of age-related macular degeneration and to identify factors that affect their level of knowledge.Patients and Methods: A cross-sectional study design was employed to collect data from 607 healthcare professionals in Gondar City from August 1 to 30, 2024. …”
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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,* Jimin Wu,1,* Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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TRANSUMBILICAL LAPAROSCOPIC CHOLECYSTECTOMY VERSUS STANDARD 4-PORT LAPAROSCOPIC CHOLECYSTECTOMY – RESULTS FROM PROSPECTIVE RANDOMIZED TRIAL AND 7 YEARS OF FOLLOW-UP by G. Ganchev, A. Saroglu, A. Julianov

“…CONCLUSION: The results of this study demonstrated that both transumbilical cholecystectomy and standard 4-port cholecystectomy are equally safe and effective in the treatment of uncomplicated gallstone disease.…”
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The Interactive Care Coordination and Navigation mHealth Intervention for People Experiencing Homelessness: Cost Analysis, Exploratory Financial Cost-Benefit Analysis, and Budget I... by Hannah P McCullough, Leticia R Moczygemba, Anton L V Avanceña, James O Baffoe

“…When health care costs are reduced by 25% ($9229/$36,917; equal to 56% [$9229/$16,609] of the average cost of an inpatient visit), the benefit-cost ratio is 3.22, which means that iCAN produces US $2.22 in health care savings per US $1 spent. …”
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Association Between Serum Uric Acid Levels and Skin Cancer: Results from NHANES Data and Mendelian Randomization Analysis by Niu Y, Shi S, Chen Y, Yang S, Yan P, Kou J

“…Using Mendelian randomization (IVW as primary method, MR-Egger and weighted median as secondary approaches), GWAS data evaluated causality. …”
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Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac Arrest by Qin Y, Ma G, Xiao X, Liu Y, Zhao Z, Zhao F, Guo F, Wang S, Sun X, Gao C

“…Nevertheless, the neuroprotective effect of electroacupuncture at ST36 (EA-ST36) in CA-induced global cerebral ischemia injury and the underlying mechanisms remains unclear.Methods: Using a rat model of Asphyxial Cardiac Arrest, the neuroprotective effects of EA-ST36 were evaluated. …”
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Comparison of STAR and GOLD in Assessing Disease Severity Among High-Risk and COPD Patients: Evidence from Enjoying Breathing Program in China by Huang K, Tang X, Chu X, Niu H, Li W, Zheng Z, Peng Y, Lei J, Li Y, Li B, Yang T, Wang C

“…However, the effectiveness of STAR and GOLD staging in distinguishing disease severity in high-risk and COPD patients remained unclear.Methods: Based on Enjoying Breathing Program data through June 2023, a total of 7.924 high-risk and COPD patients were included. …”
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Genetic Alterations in HER2-Positive and Equivocal Breast Cancer by Immunohistochemistry by Tsai YF, Hsu CY, Chiu YN, Huang CC, Chou SH, Lin YS, Chao TC, Liu CY, Chiu JH, Tseng LM

“…Yi-Fang Tsai,1– 3 Chih-Yi Hsu,3,4 Yun-Ning Chiu,1,5 Chi-Cheng Huang,1,6 Shih-Hsiang Chou,1 Yen-Shu Lin,1– 3 Ta-Chung Chao,1,3,7 Chun-Yu Liu,1,3,8,* Jen-Hwey Chiu,1,2,9,* Ling-Ming Tseng1– 3 1Comprehensive Breast Health Center, Department of Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 2Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 3Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112201, Taiwan; 4Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 5Division of General Surgery, Department of Surgery, Shaung Ho Hospital, Taipei Medical University, Taipei City, 23561, Taiwan; 6Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, 100233, Taiwan; 7Division of Cancer Prevention, Department of Oncology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 8Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 9Division of General Surgery, Department of Surgery, Cheng-Hsin General Hospital, Taipei, 112401, Taiwan*These authors contributed equally to this workCorrespondence: Jen-Hwey Chiu, Comprehensive Breast Health Center, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Road, Taipei City, 112201, Taiwan, Tel +886-2-55681176, Fax +886-2-55681185, Email chiujh10@nycu.edu.twPurpose: We aimed to identify genetic alterations in groups with different HER2 immunohistochemical (IHC) scores.Patients and Methods: A total of 120 patients with HER2-positive breast cancers, including 89 cases with IHC 3+ tumors and 31 cases with IHC 2+ and positive for in situ hybridization (ISH) were enrolled. …”
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Mitochondria-Targeting Virus-Like Gold Nanoparticles Enhance Chemophototherapeutic Efficacy Against Pancreatic Cancer in a Xenograft Mouse Model by Meng Y, Chen C, Lin R, Zheng L, Fan Y, Zhang M, Zhang Z, Shi H, Zheng X, Chen J, Chen D, Teng T, Chen B

“…Gold nanoparticles (AuNPs) have emerged as promising nanocarriers to overcome the extracellular matrix barrier; however, their limited targeting precision, poor delivery efficiency, and insufficient photothermal conversion present challenges.Methods: We developed triphenyl phosphonium-functionalized high-branch gold nanoparticles, denoted as Dox@TPAu, to enhance drug delivery and targeting capabilities. …”
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Sarcopenia, Depressive Symptoms, and Fall Risk: Insights from a National Cohort Study in the Chinese Population by Zhang X, Ye D, Dou Q, Xie F, Zeng R, Zhu K, Zhu W, Zhu A, Chen L, Wu Y, Fan T, Peng P, Huang Y, Xiao S, Bian J, Shi M, Wang J, Zhang W

“…This study aims to assess the combined influence of sarcopenia and depressive symptoms on the occurrence of falls in the Chinese population.Methods: The analysis included 8,405 participants from the China Health and Retirement Longitudinal Study (CHARLS), conducted from 2011 to 2015. …”
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VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation by Wu W, Cai H, Nan Y, Tang J, Wang Y

“…In this paper, we identified new susceptibility genes in RA and investigated their underlying mechanisms using integrated Mendelian randomization (MR) analysis.Methods: Two-sample MR analyses were used to determine the causative links among eQTLs, metabolites, and RA risk. …”
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Effects of pelvic obliquity and limb position on radiographic leg length discrepancy measurement: a Sawbones model by Mohammed Nazmy Hamad, Isaac Livshetz, Anshum Sood, Michael Patetta, Mark H. Gonzalez, Farid A. Amirouche

“…In the present study, we sought to characterize the effects of varying degrees of lateral pelvic obliquity (PO) and mediolateral limb movement in the coronal plane on LLD measurement error (ME). Methods A 3‐D sawbones model of the pelvis with bilateral femurs of equal‐length was assembled. …”
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Correlation Between Blood Pressure Variability and Serum Vascular Endothelial Growth Factor Concentration in Patients with Type I Cerebral Small Vessel Disease by Yang H, Wang Q, Li M, Yu J, Li H, Zhang S, Qian H

“…Hua Yang,1,2,* Qianyao Wang,3,* Min Li,1,* Jin Yu,1 Hua Li,1 Shufeng Zhang,1 Hairong Qian3 1Department of Neurology, The First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China; 2Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education; Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 3Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hairong Qian, Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China, Email qianhairong_cn@163.comObjective: To investigate the relationship between blood pressure variability (BPV) and serum vascular endothelial growth factor (VEGF) levels in patients with type I cerebral small vessel disease (CSVD).Methods: 144 Patients admitted to the Neurology Department of our Hospital between December 2021 and December 2022 were included and categorized into 5 groups according to CSVD burden, which was evaluated based on MRI findings. …”
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Prognostic Role of SETDB2 in Clear Cell Renal Cell Carcinoma: Linking Immune Infiltration, Cuproptosis, and Tumor Suppression by Lu SH, Lui K, Qian Y, Zhou WY, Mu YY, Zhang W

“…SET domain bifurcated histone lysine methyltransferase 2 (SETDB2) belongs to the Su(var)3– 9 subfamily of methyltransferases and has been linked to various forms of cancer, but the role it plays in ccRCC remains to be fully established.Methods: Data on SETDB2 expression were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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Facemask-wearing behavior to prevent COVID-19 and associated factors among public and private bank workers in Ethiopia. by Seada Hassen, Metadel Adane

“…To address this gap and to consider intervention measures that encourage the wearing of facemasks, this study was conducted to identify behaviors of facemask wearing and associated factors among bank workers in Dessie City, Ethiopia.<h4>Materials and methods</h4>An institution-based cross-sectional study was conducted among 413 bank workers who were selected using a simple random sampling technique from January 1st to 30th, 2021 in Dessie City, Ethiopia. …”
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