Combining Immersive Simulation with a Collaborative Procedural Training on Local Anesthetic Systemic Toxicity and Fascia Iliaca Compartment Block: A Pilot Study by Katherine B. Griesmer, Maxwell Thompson, Briana Miller, Guihua Zhai, Jaron Raper, Andrew Bloom

“…There was a positive trend in perceived confidence and knowledge with visualizing relevant anatomy (4.0 [2.0–6.0] vs 9.0 [7.5–10.0], P = 0.10), performing FICB (4.0 [1.0–5.0] vs 9.0 [7.0–10.0, P = 0.08]), and perceived ability to teach their peers (3.0 [1.0–5.0] vs 8.5 [7.0–10.0], P = 0.20). …”
Get full text

Prediction of metastatic risk of renal clear cell carcinoma based on CT radiomics analysis by Xueyi Wang, Youchang Yang, Jiaojiao Wu, Xiaoqiang Tang, Yao Wang

“…ObjectiveTo investigate the value of using imaging histological models to non-invasively assess the risk of metastasis in patients with clear cell renal cell carcinoma (ccRCC).MethodsThis study retrospectively enrolled 273 clear cell renal cell carcinoma (ccRCC) patients from three hospitals, with 57 cases allocated as an independent test cohort. …”
Get full text

A single-blind randomized controlled trial of celiac plexus block for analgesia after whipple surgery by Minpu Li, Lili Fang, Taotao Xing, Chenyang Wang, Shuyi Chen, Shui Yu, Jiali Zhu

“…Pain scores assessed using the Visual Analog Scale were consistently lower in group NB at all postoperative time points (all P < 0.05). …”
Get full text

Investigating the Trajectories of Poor Vision in Children and Adolescents in Wuhan, China From 2016 to 2019: Prospective Cohort Study by Lijuan Xu, Hanjia Li, Fang Li, Tinghui Zhang, Jingyan Yan, Hong Yan, Lu He, Bin Yu

“…Vision condition was measured using the standard logarithmic visual acuity charts. A group-based trajectory model was used to identify trajectories of poor vision overall and by gender and region. …”
Get full text

Efficacy and safety of leflunomide in patients with rheumatoid arthritis in real-life clinical practice (results of the Russian multicenter surveillance study) by R.M. Balabanova, T.B. Dubinina, D.V. Goryachev, E.L. Shakhramanova, O.N. Anoshenkova, N.R. Degula

“…The number of painful swollen joints and pain intensity according to the Visual Analog Scale (VAS) were assessed. The patients were subjected to laboratory exam- ination (blood test; ESR test; C-reactive protein (CRP) test). …”
Get full text

Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients by B. Anguelov, A. Toshev

“…Purpose: То assess the values of the top five topographic parameters of optic nerve head (ONH) obtained by Heidelberg retina tomograph (HRT) II in volunteers and primary open angle glaucoma (POAG) patients with different stage of perimetric changes.Methods: 73 eyes (38 volunteers at the age of 56 years ±13, 11 men and 27 women) and 170 eyes (90 patients at the age of 66 years ±12, 33 men and 57 women) were examined. …”
Get full text

Cerebral hemodynamics evaluation of FLAIR vascular hyperintensity in TIA patients with large artery severe stenosis or occlusion by Lichuan Zeng, Lichuan Zeng, Jiamei Wang, Qu Wang, Yaodan Zhang, Huaqiang Liao, Wenbin Wu

“…All individuals underwent pseudo-continuous ASL perfusion imaging, utilizing distinct PLD durations (1,525 and 2,525 ms) alongside qualitative visual assessments of ASL perfusion irregularities. …”
Get full text

Multicenter Longitudinal Observational Study Pharmaceuticals Alflutop in Russia (message 2) by A. M. Lila, E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova

“…Prevention, management of risk factors, and early treatment of OA are critical.Objective of the ISKRA study was to evaluate the efficacy of Alflutop in patients with OA of different locations and/or low back pain (LBP) with or without concomitant diseases.Material and methods. We selected 11,136 patients with OA of specific localizations aged 50 to 72 years. …”
Get full text

Percutaneous Endoscopic Backhand Holding (EBH) Technique for Extraforaminal Lumbar Disc Herniations: A Modified Operative Technique by Kong M, Gao C, Hao M, Ma X, Zhao J, Luan J, Lin Y, Jin C, Li Q

“…Significant improvement in back and leg pain was observed in visual analogue scale (VAS) score, and the mean ODI was decreased from preoperative 78% (range = 60– 98%) to postoperative 30% (20– 40%) (P < 0.001) at 1-month follow-up and obtained further improvement at 1 year (mean ODI = 11%; range = 2– 20%). …”
Get full text

Kruppel-like factor 9 may regulate the inflammatory injury of chondrocytes by affecting NF-κB signaling by Haoye Gu, Xingming Han, Yong Ding, Jianhua Deng

“…This study aimed to investigate the relationship between KLF9 and the pathogenesis of OA. Methods KLF9 expression in the Gene Expression Omnibus database was analyzed, and the most significantly upregulated and downregulated genes were visualized using a volcano map. …”
Get full text

Predicting hypoglycemia in elderly inpatients with type 2 diabetes: the ADOCHBIU model by Rui-Ting Zhang, Yu Liu, Chao Sun, Quan-Ying Wu, Hong Guo, Gong-Ming Wang, Ke-Ke Lin, Jing Wang, Xiao-Yan Bai

“…The purpose of the study is to construct a nomogram prediction model for the risk of hypoglycemia in elderly inpatients with T2DM and to evaluate the predictive performance of the model.MethodsFrom August 2022 to April 2023, 546 elderly inpatients with T2DM were recruited in seven tertiary-level general hospitals in Beijing and Inner Mongolia province, China. …”
Get full text

Strength-agility and fine motor are differently associated with non-verbal intelligence in dependency to sex and age in school children: Structural equation modelling multigroup ap... by Martin Musálek, Chipo Malambo, Jan Chrudimský, Jakub Kokštejn, Radka Bačáková, Šárka Vokounová

“…Background: In today's digital age, demanding to interpret vast quantities of visual information with speed and accuracy, nonverbal Intelligence has become increasingly crucial for children, as it plays a key role in cognitive development and learning. …”
Get full text

Treatment of patients with acute and subacute lumbodynia and lumbar ischialgia by V. A. Parfenov, A. I. Isaikin, T. I. Kuzminova, O. A. Chernenko, O. V. Milovanova, A. V. Romanova, N. D. Samkhaeva, Yu. M. Shor

“…Pain intensity was assessed using a visual analogue scale (VAS); functional limitation was rated according to the Roland–Morris scale (RMS). …”
Get full text

PO26 | Non-canonical coagulation platelets function: monocyte-platelet interaction a bridge between inflammation and coagulation

“…Results: Whole blood CytoFLEX SRT cytometry proved to be an effective method for distinguishing MPAs of varying sizes from free circulating platelets. …”
Get full text

The impact of local symptoms on health‐related quality of life in vulvar cancer survivors—A nationwide prospective study by Diana Zach, Pernille T. Jensen, Henrik Falconer, Zuzana Kolkova, Katja Stenström Bohlin, Preben Kjølhede, Ivette Raices Cruz, Elisabeth Åvall‐Lundqvist, Angelique Flöter Rådestad

“…Heatmaps were used to visualize proportional changes in the prevalence of symptoms at baseline and 12 months after treatment. …”
Get full text

Evaluation of the effectiveness of conservative treatment of patients with stage III osteoarthritis of the knee joint using functional unloading orthoses with the possibility of va... by M. A. Makarov, V. A. Nesterenko, V. E. Bialik, E. G. Zotkin, E. I. Bialik, S. A. Makarov, A. E. Karateev, A. A. Bialik

“…To evaluate the results, pain intensity was determined using a visual analog scale (VAS) and knee joint function according to the knee injury and osteoarthritis KOOS (Knee injury and Osteoarthritis Outcome Score) questionnaire before using the orthosis, after 1 and 3 months. …”
Get full text

A Prospective Interventional Study to Assess Functional Outcomes of Suprapatellar vs Infrapatellar Approaches for Intramedullary Interlocking Nailing in Tibial Shaft Fractures by Santhosh Kumar Kesavan, Dilip Kumar Naidu, Sabari Vaasan L, Rajavel Kalirajan, Gowthaman Nambiraj, Kevin J Dhas

“…Clinical outcomes were assessed using the visual analog scale (VAS), Lysholm knee scoring scale (LKSS), and lower extremity functional scale (LEFS). …”
Get full text

Medium- and long-term results of high tibial osteotomy in patients with primary and secondary knee osteoarthritis with varus deformity by V. E. Byalik, S. A. Makarov, L. I. Alekseeva, E. I. Byalik

“…Preoperative planning was performed using the Miniaci method; the X-ray stage of knee OA was evaluated according to the Kellgren–Lawrence classification. …”
Get full text

Ketamine for the treatment of prehospital acute pain: a systematic review of benefit and harm by Leif Rognås, Lasse Raatiniemi, Mårten Sandberg, Per Kristian Hyldmo, Poul Kongstad, Kristian Dahl Friesgaard, Robert Larsen, Vidar Magnusson, Jouni Kurola, Marius Rehn, Gunn Elisabeth Vist

“…We aimed to assess the effect and safety profile of ketamine compared with other analgesic drugs (or no drug) in adult prehospital patients with acute pain.Methods A systematic review of clinical trials assessing prehospital administration of ketamine in analgesic doses compared with other analgesic drugs or no analgesic treatment in adults. …”
Get full text

Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway by Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao

“…Filipin III cholesterol staining was employed to visualize membrane and intracellular cholesterol in the different cell models, and fluorescence intensity was assessed using confocal microscopy. …”
Get full text