Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles by O. A. Puchenkova, O. V. Shheblykina, D. A. Kostina, A. A. Bolgov, P. R. Lebedev, V. V. Molchanov, T. G. Pokrovskaya, M. V. Korokin, E. A. Nikiforov, N. F. Vaskina, T. A. Idrisov, T. D. Moseev, V. V. Melekhin, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin

“…To study the acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles.Materials and methods. The study was performed on white laboratory female BALB/c mice (n=57) and male C57Bl/6 mice (n=66). …”
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Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis by Elizabeth Gorman, Hongzheng Dai, Hongzheng Dai, Yanming Feng, William James Craigen, William James Craigen, David C. Y. Chen, Fan Xia, Fan Xia, Linyan Meng, Linyan Meng, Pengfei Liu, Pengfei Liu, Robert Rigobello, Arpita Neogi, Christine M. Eng, Christine M. Eng, Yue Wang, Yue Wang

“…To assess the clinical utility of this approach, we describe the results from a retrospective review of patients having dual genome panel testing for mitochondrial disease.MethodsDual genome panel testing by NGS was performed on a cohort of 1,509 unrelated affected individuals with suspected mitochondrial disorders. …”
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Fluticasone propionate in chronic rhinosinusitis with nasal polyps (CRSwNP): an artificial intelligence-driven consensus by Emilio Avallone, Raffaella Iannella, Antonella Di Lullo, Michele Grasso, Salvatore Musto, Enzo Piermichele Troncone, Giuseppe Tortoriello, Bernardino Cassiano, Simona Nappi, Gianluca Bava, Giovanna Piazzetta, Giovanni Tomacelli, Aurelio D’Ecclesia, Giacomo Spinato, Giacomo Matrone, Doriano Politi, Carlo De Luca, Claudio Caporale, Livio Presutti, Livio Presutti, Gabriele Molteni, Gabriele Molteni, Ernesto Pasquini, Francesco Panu, Simonetta Masieri, Stefano Di Girolamo, Giulio Cesare Passali, Luca de Campora, Giandomenico Maggiore, Domenico Di Maria

“…Treatment with FP was associated with a reduction in the recurrence of nasal polyps and an improvement in the patient's quality of life.ConclusionsFP, as other equal corticosteroids, represents a first-line local therapy for patients with CRSwNP without complicating comorbidities due to its high efficacy and low systemic bioavailability. …”
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Combined arthroscopic rotator cuff repair with mesenchymal stem cell augmentation shows similar functional outcomes but a higher structural integrity rate compared with isolated re... by Erminia Cofano, MD, PhD, Roberto Minici, MD, Giovanna Spina, MD, Domenico Laganà, MD, Olimpio Galasso, MD, Giorgio Gasparini, MD, Michele Mercurio, MD

“…The data extracted for quantitative analysis included the visual analog scale, University of California at Los Angeles score, flexion, external rotation, and retear. …”
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Translingual neural stimulation induced changes in intra- and inter-network functional connectivity in mild-moderate traumatic brain injury patients by Daniel Y. Chu, Jiancheng Hou, Thomas Hosseini, Veena A. Nair, Nagesh Adluru, Yuri Danilov, Kurt A. Kaczmarek, Mary E. Meyerand, Mitchell Tyler, Mitchell Tyler, Vivek Prabhakaran

“…Moreover, significant increases in intra- and inter-network RSFC were observed, particularly within the visual, default mode, dorsal attention, frontoparietal (FPN), and somatosensory (SMN) networks. …”
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Treatment success rate and time to culture conversion under a prospective BPaL cohort study by E. Burhan, J. Sugiharto, M. Soemarno, A. Juan, Y. Runtu, A. Yuvensia, R. Ramadhani, J. Sabono, A. Lailiyah, F. Fenni, M. Farikha, T. Pakasi, I. Pambudi, M. Mbenga, I. Koppelaar, V. Mirtskhulava, F. Wares, D. Jerene, J.K. Jung, J.S. Lee, S. Foraida, S. Juneja, M. Diachenko, A. Gebhard

“…The lack of observed statistical differences in the TSCC across variables shows that the BPaL treatment will be equally effective in all patient groups.…”
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The talent project and the validation of standards for the identification of student-athlete talent by Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Antonino Bianco, Martina Albanese, Laura Capranica, Laura Capranica, Mojca Doupona, Mojca Doupona, Epameinondas Koutavelis, Georgia Alexandrou, Olia Tsivitanidou, Tea Gutović, Ivica Zelić, Dražen Čular, Dino Mujkic, Siniša Kovač, Damira Vranesic- Hadzimehmedovic, Zoran Milanović, Zoran Milanović, Zoran Milanović, Nenad Stojiljković, Nemanja Stanković, Ana Kezić

“…IntroductionThe aim of the TALENT project is to promote equality in education, prevent exclusion, support dual careers (sport and school), create new role models for the benefit of young talents and prepare them for lifelong learning and professional sport from an early age. …”
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A bibliometric analysis of the current state of research on family interventions for ASD by Xuhui Meng, Xuhui Meng, Xuhui Meng, Xuhui Meng, Xue Zhou, Xue Zhou, Xue Zhou, Xue Zhou, Jiahui Luo, Jiahui Luo, Jiahui Luo, Jiahui Luo, Jiaxia Li, Jiaxia Li, Jiaxia Li, Jiaxia Li, Li Zhou, Li Zhou, Li Zhou, Li Zhou, Yuhan Zhang, Yuhan Zhang, Yuhan Zhang, Yuhan Zhang

“…The results were visualized and analyzed.ResultsA total of 1,891 documents were retrieved. …”
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LEVELS OF ANGIOGENESIS-REGULATORY CHEMOKINES IN THE SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS by D. A. Zhebrun, A. L. Maslyansky, A. G. Titov, A. P. Patrukhin, A. A. Kostareva, I. S. Goltseva, N. A. Arsentyeva, N. E. Lyubimova, A. A. Totolyan

“…There was a direct correlation between SF levels of CCL5/RANTES and DAS28, as well as patient global disease activity assessment on visual analogue scale, and that between the level of CCL2/MCP-1 in the SF and that of anticyclic citrullinated peptide (anti-CCP) antibodies in the serum. …”
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Thalamic functional dysconnectivity in patients with left-hemisphere chronic capsular and pontine stroke by Jun Guo, Jun Guo, Hongchuan Zhang, Hongchuan Zhang, Jingchun Liu, Caihong Wang, Chen Cao, Jingliang Cheng, Chunshui Yu, Wen Qin

“…However, the differential involvements of thalamic functional connectivity in chronic capsular and pontine stroke are still unknown.MethodsThe research recruited 66 left-lesion chronic stroke patients, including 46 capsular strokes (CS) and 20 pontine stroke (PS) patients, and 67 normal controls (NC). …”
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From digitized whole‐slide histology images to biomarker discovery: A protocol for handcrafted feature analysis in brain cancer pathology by Xuanjun Lu, Yawen Ying, Jing Chen, Zhiyang Chen, Yuxin Wu, Prateek Prasanna, Xin Chen, Mingli Jing, Zaiyi Liu, Cheng Lu

“…In this study, we present a protocol for handcrafted feature analysis in brain cancer pathology (PHBCP) to systematically extract, analyze, model, and visualize handcrafted features from WSIs. The protocol enabled the discovery of biomarkers from WSIs through a series of well‐defined steps. …”
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Impact of the Timing of Rocuronium Injection after Propofol Administration on Temporal Summation of Pain in Gynecologic Laparoscopic Surgery: A Prospective and Controlled Study by Jaehak Jung, Byoungryun Kim, Seong Nam Park, Jiheui Lee, Insung Choi, Myeong Jong Lee, Hyeonbin Yim, Cheol Lee, JuHwan Lee

“…This study aimed at determining the impact of the timing of rocuronium after induction with propofol on the temporal summation of pain. Methods. One hundred patients aged 19–60 years underwent gynecologic laparoscopic surgery. …”
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Combining radiomics and deep learning to predict liver metastasis of gastric cancer on CT image by Yimin Guo, Yimin Guo, Haixiang Yin, Haixiang Yin, Hanyue Zhang, Hanyue Zhang, Pan Liang, Pan Liang, Jianbo Gao, Jianbo Gao, Ming Cheng, Ming Cheng

“…This score, along with statistically significant clinical factors, was used to build a fused model which visualized as a nomogram. The model’s predictive performance, calibration, and clinical utility were assessed and compared against a clinical model. …”
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Comparison of Transforaminal Percutaneous Endoscopic Lumbar Discectomy with and without Foraminoplasty for Lumbar Disc Herniation: A 2-Year Follow-Up by Binbin Wu, Gonghao Zhan, Xinyi Tian, Linyu Fan, Chenchen Jiang, Beekoo Deepti, Hong Cao, Jun Li, Qingquan Lian, Xixi Huang, Feng Xu

“…However, the safety and effectiveness between the TF PELF and TF PELD have not been investigated. Methods. Of the included 140 LDH patients, 62 patients received TF PELF (PELF group) and 78 patients received TF PELD (PELD group). …”
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Anoikis classification of lung squamous cell carcinoma reveals correlation with clinical prognosis and immune characteristics by Yixin Zhai, Cheng Li, Xiang He, Wenqi Wu, Donghui Xing, Kaiping Luo, Zhigang Zhao

“…We constructed a risk score and provided a visual representation of the prophetic implications of the ARGs-based signature through a nomogram. …”
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Analysis of the changes in corneal optical density following small incision lenticule extraction for myopia and related influencing factors by Yifan Du, Yu Di, Shan Yang, Ying Li

“…Purpose: To examine changes in corneal optical density (COD) following small incision lenticule extraction (SMILE) for myopia and the associated factors affecting COD. Methods: One hundred and ten eyes of 110 subjects who underwent SMILE were included in this study. …”
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Reducing Postoperative Neurological Complications in Uniportal Full-Endoscopic Lumbar Interbody Fusion: Efficacy of the GUARD Technique Combined With Delayed Ligamentum Flavectomy by Hao-Chun Chuang, Yu-Chia Hsu, Yuan-Fu Liu, Chao-Jui Chang, Yu-Meng Hsiao, Yi-Hung Huang, Keng-Chang Liu, Chien-Min Chen, Hyeun Sung Kim, Cheng-Li Lin

“…Patient-reported outcomes included the visual analogue scale (VAS) for leg and back pain, and Oswestry Disability Index. …”
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Arthroscopic Latarjet combined with remplissage and capsulolabral repair in the treatment of anterior shoulder instability—the quadruple effect. A prospective study of functional o... by Ayyappan V. Nair, DOrtho, DNB, MNAMS, Bharath Bharadwaj M S, MS Ortho, DNB(Ortho), Maythilisharan Rambhojan, MS Ortho, Sreejith Thampy J, MS Ortho, Aravind Rajan, MS Ortho, DNB ORTHO, Kiran V, MS Ortho, MRCS (Edinburgh), Prince Shanavas Khan, DOrtho, MS Ortho

“…To this effect, remplissage has had a proven track record in combination with Bankart repair. Methods: The functional and clinical outcomes of patients having undergone arthroscopic Latarjet with remplissage with a minimum of 2 years and secondarily, the external rotation was assessed postoperatively. …”
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An explainable radiomics-based machine learning model for preoperative differentiation of parathyroid carcinoma and atypical tumors on ultrasound: a retrospective diagnostic study by Chunrui Liu, Wenxian Li, Baojie Wen, Haiyan Xue, Yidan Zhang, Shuping Wei, Jinxia Gong, Li Huang, Jian He, Jing Yao, Zhengyang Zhou

“…The explainable bar chart, heatmap and Shapley Additive exPlanations (SHAP) values were used to explain and visualize the main predictors of the optimal model.ConclusionThis radiomics framework provides a promising tool to support doctors in the clinical management of parathyroid lesions.…”
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Beyond the tray: analyzing hospital plate waste for economic and environmental sustainability by Mohamad G. Abiad, Maha Hoteit, Maha Hoteit, Maha Hoteit, Maroun Khattar, Ferial Fattouh, Dana Malli, Esraa Antar, Jana El Cheikh Mohammad, Nour Badereddine, Sami El Khatib, Sami El Khatib, Hussein F. Hassan

“…Plate waste % was calculated by collecting the waste at each meal after collecting the trays from the patients’ rooms to the kitchen, either through weighing or by visual estimation. To calculate the economic implication, the amount of each ingredient of the wasted food in grams was multiplied by its corresponding price, expressed as USD per hospital bed per day. …”
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