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25161
Analysis of the distribution and persistence of organophosphorus pesticides malathion and diazinon in herbal plants
Published 2024-09-01“…All of the plants were divided into three equal groups. Young plant shoots were processed twice with "Aliot" products containing 570 g/l of malathion and "Terradox" containing 40 g/kg of diazinon. …”
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25162
Multi-Response Au-Nanohybrid Composite Triggered NIR-Light for Effective Anti-Tumor Therapy in Animal Model
Published 2025-06-01“…While targeted nanomedicines are highly regarded for their potential, they are not spared from issues of colloidal instability and uncontrolled drug release.Methods: The hybrid system (Au@SiO2-HA-DOX) was designed to enhance colloidal stability and facilitate controlled drug delivery by coating gold nanorods with silica shells and hyaluronic acid (HA) for tumor targeting. …”
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25163
Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing and Machine Learning
Published 2024-12-01“…In this study, we elucidated the mechanism whereby macrophages promote AAA development and identified associated biomarkers, with the goal of developing new targeted therapies and improving patient outcomes.Patients and Methods: Differential expression analysis, weighted gene co-expression network analysis, and single-cell analysis were used to identify macrophage-related genes in an AAA dataset. …”
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25164
Effectiveness of an Individualized Diabetes Health Education Program Using Real-Time Continuous Glucose Monitoring in Improving Blood Glucose: A Pilot Interventional Study on Subje...
Published 2025-06-01“…This study evaluated whether an individualized diabetes health education program using RT-CGM could improve glycemic control compared to general dietary guidance in prediabetic individuals.Methods: In this randomized controlled trial conducted at Guangdong Provincial People’s Hospital (initiated September 2022), we enrolled 41 adults (> 18 years) with prediabetes, randomly assigning them to either: (1) RT-CGM group (n=20) receiving meal adjustments based on continuous glucose data and energy balance, or (2) control group (n=21) receiving adjustments based solely on energy balance. …”
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25165
Development and Validation of a Risk Predictive Model for Adverse Postoperative Health Status of Elderly Patients Undergoing Major Abdominal Surgery Using Lasso-Logistic Regression
Published 2025-02-01“…The aim of this study was to identify risk factors that can predict the health status of patients aged 80 and over after major abdominal surgery and to establish a nomogram model.Methods: We conducted a retrospective study of elderly patients (aged 80+) who underwent major abdominal surgery at the First Affiliated Hospital of Soochow University from January 2017 to June 2023. …”
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25166
The Neutrophil Percentage-to-Albumin Ratio as a New Predictor of All-Cause Mortality in Maintenance Hemodialysis Patients
Published 2025-07-01“…This study aimed to investigate the association between NPAR and all-cause mortality in MHD patients.Methods: Patients undergoing maintenance hemodialysis in the blood purification department of The First Affiliated Hospital of Guangxi Medical University from January 2021 to June 2021 were prospectively studied. …”
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25167
Coix Seed Oil Alleviates DSS-Induced Ulcerative Colitis via Intestinal Barrier Repair and Ferroptosis Regulation
Published 2025-02-01“…Here, the effects and mechanisms of CSO on ulcerative colitis (UC) in vivo are systematically investigated.Methods: Firstly, the UC mice was replicated by 3% DSS, and assessed the efficacy of CSO by observing the fecal occult blood, colon length, DAI score and pathological histomorphological changes of colon tissues. …”
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25168
Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer
Published 2025-01-01“…This study aimed to develop a novel diagnostic model based on miRNAs from glycosylated extracellular vesicles and evaluate its effectiveness in diagnosing gastric cancer.Methods: GlyExo-capture technology was used to isolate glycosylated extracellular vesicles from serum samples. …”
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25169
PM2.5 Induces Cell-Specific Transcriptomic Alterations in the Lungs of Juvenile Mice
Published 2025-07-01“…However, its cell-type-specific effects on the lungs and the underlying molecular mechanisms remain poorly defined.Methods: This study established a juvenile mouse model of PM2.5 airway exposure to assess transcriptional alterations in lung cells via single-cell RNA sequencing (scRNA-seq). …”
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25170
Hemiarthroplasties via Posterior Trochanter Osteotomy for Treating Femoral Neck Fractures in Post-Cerebrovascular Disease
Published 2025-06-01“…Ying-Ao Jia,1,* Li-Na Qiao,2,* Zhi-Bin Liu,1 Liang Xue,1 Wei-Ming Bi,1 Meng-Fei Chen,1 Kai Kang,1 Fei Wang1 1Department of Orthopaedics, Affiliated Hospital of Yan’an University, Yan’an, 716000, People’s Republic of China; 2Department of Pathology, Affiliated Hospital of Yan’an University, Yan’an, 716000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Wang, Department of Orthopaedics, Affiliated Hospital of Yan’an University, Yan’an, Shaanxi, 716000, People’s Republic of China, Tel +86 18691133000, Email ww_ff@sina.comObjective: The study investigated to examine the clinical outcomes of hemiarthroplasties using posterior femoral trochanter osteotomy for the treatment of femoral neck fractures in patients at the sequelae stage of cerebrovascular disease.Methods: A retrospective analysis was conducted on the data of 53 patients who had been admitted to the Department of Orthopedics at Yan’an University Affiliated Hospital between May 2020 and May 2023. …”
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25171
A cash transfer plus gender transformative economic empowerment intervention seeking to improve the wellbeing of caregivers of children and adolescents living with HIV in South Afr...
Published 2025-04-01“…Methods Caregivers of CALHIV will be recruited from public sector HIV clinics within the eThekwini Municipality, KwaZulu-Natal, South Africa. …”
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25172
Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics
Published 2025-03-01“…Our study aims at exploring the genetic-level pathogenic mechanism of these two diseases.Methods: We carried out bioinformatics analysis on the GSE55235 and GSE213001 datasets. …”
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25173
Patient and public involvement and engagement with underserved communities in dementia research: Reporting on a partnership to co‐design a website for postdiagnostic dementia suppo...
Published 2024-02-01“…These seven members of the public undertook the role of partners in the study. They all equally contributed to the study design, recruitment of participants, development and revision of topic guides for the interviews and development of the website. …”
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25174
Long-term results of lymphedema treatment with Combined lymph node transfer and collagen scaffolds: An Observational Study
Published 2025-03-01“…Our observational study aimed to examine the hypothesis that nanofibrillar collagen scaffolds (NCS) combined with VLNT can provide guided lymphagiogenesis creating long-lasting lymphatic pathways. Methods: Twenty-four patients (21 female, 3 male) underwent a lymphatic microsurgery for upper (n = 11) or lower (n = 13) limb secondary lymphedema and completed at least 18 months follow-up were selected and equally divided in 2 groups; Group-A underwent VLNT, Group-B underwent combined VLNT and NCS procedure. …”
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25175
Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation
Published 2025-01-01“…This study explores the complex immunometabolic landscape of RA to identify potential therapeutic targets.Patients and Methods: We integrated genome-wide association study (GWAS) data involving 1,400 plasma metabolites, 731 immune cell traits, and RA outcomes from over 58,000 participants. …”
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25176
Effectiveness of Finnish SISU training in enhancing prehospital personnels’ work performance: A randomised controlled pilot study
Published 2025-05-01“…The sample comprised 16 paramedics, divided equally between the intervention and control groups. …”
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25177
Design, Synthesis, and Biological Evaluation of Novel Hydroxytyrosol Derivatives as Protectors for Vascular Endothelium Against Lipid Overload
Published 2025-04-01“…The aim of the study was to design and synthesize novel hybrid molecules to improve HT’s biological efficiency.Materials and Methods: A pharmacophore connection strategy was used to design and synthesize novel hybrid molecules by combining HT or its analogues with adamantane (ADM). …”
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25178
Working time distribution and administrative burden in Austrian community health nursing: A cross-sectional survey
Published 2025-12-01“…Tweetable abstract: Study of Austrian community health nurses reveals: for every hour with clients, nurses spend an equal hour on administration. Administrative burden grows disproportionately with longer working hours, with no efficiency gains.…”
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25179
Bidirectional Relationship Between Hypoalbuminemia and Postoperative Pneumonia in Elderly Hip Fracture Patients: A Retrospective Cohort Study
Published 2025-08-01“…However, their bidirectional relationship in elderly HF patients remains underexplored.Methods: This retrospective cohort study was conducted in China enrolling elderly patients (≥ 65 years) with HFs between Mar 2020 and Feb 2023. …”
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25180
Opaganib Promotes Weight Loss and Suppresses High-Fat Diet-Induced Obesity and Glucose Intolerance
Published 2025-04-01“…Additionally, opaganib and semaglutide were equally effective in promoting body weight loss and improving glucose tolerance in obese mice. …”
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