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24901
Ultrasmall Antioxidant Copper Nanozyme to Enhance Stem Cell Microenvironment for Promoting Diabetic Wound Healing
Published 2024-12-01“…Strategies to overcome these challenges are essential to enhance the therapeutic potential of stem cell therapy.Methods: Cu5.4O ultrasmall nanoparticles (Cu5.4O-USNPs), known for their excellent reactive oxygen species (ROS) scavenging properties, were utilized to protect adipose-derived stem cells (ADSCs) from oxidative stress injury. …”
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24902
Parametric Population Pharmacokinetics Model Repository of Rifampicin: Model-Informed Individualized Therapy
Published 2025-04-01“…This study aims to construct a comprehensive rifampicin popPK model repository to support model-informed individualized therapy.Methods: A systematic review was conducted using PubMed, Web of Science, and Embase databases up to September 2023 to retrieve popPK model articles on rifampicin. …”
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24903
Beam hardening of K-edge contrast agents: a phantom study comparing clinical energy-integrating detector and photon-counting detector CT systems
Published 2025-03-01“…Photon-counting detectors (PCD) are more susceptible to BH due to equal weighting of photons regardless of their energies. …”
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24904
Real-World Effectiveness of Nirmatrelvir/Ritonavir in Hospitalized Older Adults with Severe Omicron COVID-19: A Retrospective Cohort Study from China
Published 2025-06-01“…We aimed to estimate the effectiveness in older patients aged 80 and above with severe COVID-19.Methods: A retrospective study analyzed 263 COVID-19 patients aged 80 and above, admitted to the Department of Geriatrics at Jinling Hospital, affiliated with Nanjing University, between December 15, 2022, and January 15, 2023. …”
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24905
Safety and Tolerability of Contezolid Versus Linezolid for Short-Term Treatment of Rifampicin-Resistant Pulmonary Tuberculosis: A Randomized Controlled Study
Published 2025-07-01“…Safer alternatives to linezolid are needed to address the safety concerns.Patients and Methods: A total of 27 patients with RR-TB (including MDR-TB) were randomly assigned to receive either contezolid (n=14) or linezolid (n=13) in combination with standardized background anti-TB regimens, that is, linezolid-bedaquiline (pyrazinamide)-levofloxacin (moxifloxacin)-cycloserine-clofazimine or contezolid-bedaquiline (pyrazinamide)-levofloxacin (moxifloxacin)-cycloserine-clofazimine. …”
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24906
Fluctuations of Anterior Chamber Depth and Astigmatism in Pseudophakic Eyes
Published 2024-12-01“…Larysa Tutchenko,1,* Sudi Patel,2,* Mykhailo Skovron,1,* Oleksiy V Voytsekhivskyy,1,* Fanka Gilevska3,* 1Department of Corneal Pathology, Ophthalmic Oncology and Oculoplasty, Kyiv Clinical Ophthalmology Hospital Eye Microsurgery Center, Kyiv, 03680, Ukraine; 2Department of Cataract and Refractive Surgery, University Eye Clinic Svjetlost, Zagreb, 10000, Croatia; 3Department of Refractive Surgery, Eye Clinic Sistina Oftalmologija, Skopje, 1000 Republic of North Macedonia*These authors contributed equally to this workCorrespondence: Sudi Patel, Department of Cataract and Refractive Surgery, University Eye Clinic Svjetlost, Heinzelova 39, Zagreb, 10000, Croatia, Email drsudipatel1@gmail.comPurpose: To explore the significance of changes in anterior chamber depth (ΔACD) and astigmatism between 4 and 8 weeks following uneventful phacoemulsification.Patients and Methods: Anterior chamber depth (ACD, mm), autorefractometry and subjective refraction were monitored in pseudophakic eyes implanted with non-toric IOLs (group 1, SA60AT, n=36; group 2, SN60WF, n=34; group 3, ICBOO, n=16) and phakic control group (n=30, group 4a, for ACD and autorefractometry) over four weeks. …”
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24907
Women’s Autonomy Decision Making Power on Postpartum Modern Contraceptive Use and Associated Factors in North West Ethiopia
Published 2019-01-01“…A P-value less than or equal to 0.05 at 95% confidence interval was set to test statistical significance. …”
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24908
Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression
Published 2025-03-01“…Specifically, we sought to elucidate the underlying mechanisms through which TBMS1 exerts its anticancer effects.Methods: The effects of TBMS1 on the viability, proliferation, and apoptosis of two liver cancer cell lines, MHCC97-H and SNU-449, were comprehensively assessed using Cell Counting Kit-8 (CCK-8), colony formation, 5-ethynyl-2′-deoxyuridine (EDU) assay, and flow cytometry assays. …”
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24909
The Role of Lifestyle Behaviors in Shaping the Relationship Between Chronic Pain and Epigenetic Age Acceleration: Evidence From NHANES 1998 to 2002
Published 2025-08-01“…This study aims to examine the relationship between chronic pain and epigenetic clocks in a nationally representative US sample and discover potential shared systemic mechanisms.Methods: This research comprised 2,532 individuals aged 50 and above from the 1999– 2002 National Health and Nutrition Examination Survey (NHANES) database. …”
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24910
Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidem...
Published 2024-12-01“…This study endeavors to evaluate the relationship between polymorphisms in the coding sequence (CDS) of SLCO1B1 gene and blood lipid levels before and after atorvastatin treatment among the Chinese Han adults with dyslipidemia.Patients and Methods: A total of 165 Chinese Han adults undergoing atorvastatin therapy were enrolled in this study and followed up quarterly. …”
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24911
Ridge splitting using autogenous bone wedge versus the conventional intercortical augmentation technique in horizontally deficient anterior maxilla: a randomized clinical trial
Published 2025-06-01“…Patients were divided equally into two groups. Group I received an autogenous bone wedge harvested from the chin area to be placed intercotically after ridge splitting (intervention group). …”
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24912
Preoperative Prediction of a Rare and Highly Aggressive Subtype of Hepatocellular Carcinoma Based on Multimodal Imaging and Clinical Indicators
Published 2025-06-01“…Keke Chen,1,* Yuli Zhu,1,* Han Liu,2,* Minying Deng,3 Wentao Kong,4 Wenping Wang1 1Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 2Department of Ultrasound, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 3Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 4Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wentao Kong, Email breezewen@163.com Wenping Wang, Email puguang61@126.comPurpose: To develop and validate a reliable preoperative non-invasive diagnostic model for dual-phenotype hepatocellular carcinoma (DPHCC) by integrating multimodal imaging and clinical indicators, thereby facilitating clinical decision-making.Patients and Methods: 222 pathologically confirmed patients (61 with DPHCC, 161 with non-DPHCC) were retrospectively enrolled in this study and randomly assigned to training and validation cohorts in an 8:2 ratio. …”
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24913
S-values for bone marrow dosimetry in preclinical radiopharmaceutical studies with rodents
Published 2025-07-01“…Two phantoms of different resolutions and equal mass were created. 3D dose distributions were simulated and the corresponding organ to organ S-values were calculated. …”
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24914
Evaluating the Knowledge of Computed Tomography and Magnetic Resonance Imaging Parameters Between Undergraduate Students and Radiographers in Jeddah, Saudi Arabia: A Cross-Sectiona...
Published 2025-08-01“…Previous studies have showed a significant knowledge gap regarding CT and MRI parameters; thus, this study aimed to evaluate the effectiveness of university curricula and clinical practice in hospitals among undergraduate students and technologists in Jeddah.Methods: Quantitative data were collected through a validated structured cross-sectional survey administered to a cluster sample of undergraduate students and radiographers in Jeddah. …”
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24915
Predicting OSA Using Radiographs of the Airway Anatomy
Published 2024-11-01“…., Guangzhou, 510000, People’s Republic of China; 4Department of Anesthesiology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 5Department of Otolaryngology Head and Neck Surgery, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiangmin Zhang; Feng Pang, Department of Sleep Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26 Yuanchun Two Road, Guangzhou, Guangdong, 510065, People’s Republic of China, Tel +86 15013071537, Email zhangxm36@mail.sysu.edu.cn; pangf6@mail.sysu.edu.cnObjective: This study aims to analyze the tongue body shape and upper airway anatomical parameters in patients with Obstructive Sleep Apnea (OSA) and to explore the anatomical causes of OSA.Methods: A total of 345 subjects participated in this study. …”
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24916
Comparative Analysis of Clinical Efficacy and Safety of Pyrotinib Plus Capecitabine versus Trastuzumab Emtansine (T-DM1) as Second-Line Treatment for HER2-Positive Advanced Breast...
Published 2025-04-01“…This study aims to compare the clinical efficacy and safety of T-DM1 against pyrotinib plus capecitabine.Methods: Patients are females with HER2-positive, locally advanced, or metastatic breast cancer who at least 18 years old and have received anti-HER2 therapy in the past. …”
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24917
Preoperative Neutrophil-to-Albumin Ratio as a Prognostic Indicator in Advanced Gastric Cancer Undergoing Radical Gastrectomy
Published 2025-07-01“…Huaping Ye,1,* Rong Kang,2,* Mao Chen,3 Si Zhang,3 Jinfeng Yang1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 3Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinfeng Yang, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email yangjinfeng13@163.com Si Zhang, Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email 692653629@qq.comObjective: This study aimed to evaluate the prognostic significance of the preoperative neutrophil-to-albumin ratio (NAR) in patients with advanced gastric cancer undergoing radical gastrectomy.Methods: A retrospective analysis was conducted involving 526 patients diagnosed with locally advanced gastric adenocarcinoma who underwent radical gastrectomy between January 2017 and December 2019. …”
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24918
Reliability of Cephalometric Lines as Indicators for Dentoalveolar Stability in Forensic Identification: A Cross-sectional Study
Published 2025-03-01“…Introduction: Cephalometric superimposition is an accepted method that has long been considered helpful for evaluating the growth and displacement of facial bones during orthodontic treatment. …”
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24919
Association Between Dietary Flavonoid Intake and Cardiovascular Health in Cancer Survivors: A Cross-Sectional Study
Published 2024-10-01“…The purpose of this study was to explore the associations between dietary flavonoid intake and cardiovascular health in cancer survivors.Patients and Methods: We obtained data from the National Health and Nutrition Examination Survey (NHANES) 2007– 2008, 2009– 2010, and 2017– 2018 cycles. …”
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24920
Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses
Published 2025-06-01“…However, little is known about the causal relationship between immune factors and diseases of the reproductive system.Methods: Thorough two-sample Mendelian randomization (MR) analyses were conducted to determine the causal effects of 731 immune traits on reproductive ill-health, including abnormal spermatozoa (AS), polycystic ovary syndrome (PCOS), and spontaneous abortion (SA). …”
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