Reporting of Safety Events during Anti-VEGF Treatment: Pharmacovigilance in a Noninterventional Trial by Focke Ziemssen, Thomas Hammer, Matthias Grueb, Bettina Mueller, Hüsnü Berk, Maria-Andreea Gamulescu, Jessica Voegeler, Joachim Wachtlin, OCEAN Study Group

“…The most frequent AEs by MedDRA preferred term (PT) were visual acuity reduced (3.5% of patients), intraocular pressure increased (2.5%), and drug ineffective (2.1%). …”
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HIGH HEART RATE AS A POTENTIAL RISK FACTOR FOR DEVELOPMENT OF CARDIOVASCULAR DISEASES IN WOMEN WITH RHEUMATOID ARTHRITIS by D. S. Novikova, T. V. Popkova, A. N. Gerasimov, A. V. Volkov, E. L. Nasonov

“…To study relationship between heart rate (HR) and traditional risk factors for cardiovascular diseases (TRF for CVD), subclinical structural and functional changes in the heart and vessels, as well as the activity and severity of rheumatoid inflammation in women with rheumatoid arthritis (RA). Material and methods. A total of 291 female patients less than 60 years of age with a definite diagnosis of RA were examined. …”
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Effect of Co-Administration of Midazolam and Dexmedetomidine on Haemodynamics and Stress Response in Elderly Patients with Non-Small Cell Lung Cancer by Yanjun Zhao, Dongjiao An, Liang Bi

“…Objective This study aimed to evaluate the effect of co-administration of midazolam and dexmedetomidine on hemodynamics and stress response in elderly patients with non-small cell lung cancer (NSCLC).Methods In this prospective, randomized controlled trial, 154 elderly NSCLC patients scheduled for lobectomy in our oncology department from January 2019 to December 2021 were recruited. …”
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Comprehensive geriatric assessment-based screening and integrated intervention for osteosarcopenia risk factors in older adults: an application analysis in patients aged ≥80 years... by Tian ZHANG, Jiangming SHA, Liming JIANG, Quanzhong YIN, Yihang GU

“…Objective To explore the utility of comprehensive geriatric assessment (CGA) in screening risk factors for osteosarcopenia (OS) among older adults (≥80 years old) and to evaluate the therapeutic efficacy of CGA-guided integrated interventions for OS. MethodsA total of 420 patients aged ≥80 years, recruited from the Department of Geriatrics, General Practice of The Affiliated Jiangyin Hospital of Nantong University, and community health centers from January 2022 to October 2024, were enrolled. …”
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Migraine in men – differences in phenotype and treatment patterns: results from the Migraine in Poland cross-sectional national survey by Marta Waliszewska-Prosół, Karol Marschollek, Sławomir Budrewicz, Mieszko Więckiewicz, Magdalena Nowaczewska, Marcin Straburzyński

“…The purpose of this paper is to define migraine phenotype and patterns of care for Polish men. Methods Participants were recruited through various channels, primarily targeting individuals experiencing headaches. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…ObjectivesThis study aimed to characterize the genomes of two rare ST592 Klebsiella pneumoniae isolates and to explore their evolution into carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKp).MethodsThe minimum inhibitory concentrations (MICs) were determined using a VITEK 2 compact system. …”
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A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-s... by Feng Wang, Minwei Bao, Bo Tao, Fugui Yang, Guangxue Wang, Lei Zhu

“…It could serve as a useful method to assist thoracic surgeons in improving diagnostic accuracy and has the potential to make management decisions.…”
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Associations Between Cerebral Perfusion Pressure, Hemodynamic Parameters, and Cognitive Test Values in Normal-Tension Glaucoma Patients, Alzheimer’s Disease Patients, and Healthy C... by Akvile Stoskuviene, Edvinas Chaleckas, Evelina Grusauskiene, Laimonas Bartusis, Guven Celikkaya, Ingrida Januleviciene, Antanas Vaitkus, Arminas Ragauskas, Yasin Hamarat

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Interpretable machine learning analysis of environmental characteristics on bacillary dysentery in Sichuan Province by Yao Zhang, Qiao-Lin Wang, Wei Peng, Meng-Yuan Zhang, Yao Qin, Lun Zhang, Rong-Jie Wei, Dian-Ju Kang

“…To enhance interpretability, the model’s outputs were visualized and explained using SHapley Additive Explanations (SHAP).ResultsA machine learning model was developed to assess the impact of environmental factors on BD incidence across different climate zones. …”
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Age-Related Differences in the Appetite-Regulating Hormone Response to Exercise by Christoph Höchsmann, Hyeon Jung Heselton, Safiya E Beckford, Jeffrey A French, Jeffrey R Stevens, James L Dorling, Julie B Boron, Karsten Koehler

“…Plasma concentrations of PYY 3–36 (PYY3–36), GLP-1, and acylated ghrelin, as well as subjective perceptions of hunger, fullness, thirst, and nausea (via visual analog scales), were measured before a standardized snack (fasted) and before and after a subsequent exercise/rest condition. …”
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Efficacy of virtual reality balance training on rehabilitation outcomes following anterior cruciate ligament reconstruction: A systematic review and meta-analysis. by Chao Du, Nei-Meng Gu, Tian-Ci Guo, Ai-Feng Liu

“…<h4>Objective</h4>The objective of this systematic review and meta-analysis is to clarify the rehabilitation efficacy of virtual reality (VR) balance training after anterior cruciate ligament reconstruction (ACLR).<h4>Methods</h4>This meta-analysis was registered in PROSPERO with the registration number CRD42024520383. …”
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Old world camels in Germany: parasitic nematode communities characterized by nemabiome analysis showed reduced anthelmintic efficacy according to the fecal egg count reduction test by Jenny Brachmann, Stefan Fiedler, Hannah Fischer, Jennifer S. Schmidt, Renate Radek, Georg von Samson-Himmelstjerna, Jürgen Krücken

“…This study examined the gastrointestinal parasite fauna of Old World Camels (OWCs) in Germany and evaluated the efficacy of anthelmintic treatment. Methods In total, nine German OWC-keeping farms that dewormed their stock in spring 2023 were examined. …”
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Did COVID-19 surveillance system sensitivity change after Omicron? a retrospective observational study in England by Julii Brainard, Iain R. Lake, Roger A. Morbey, Alex J. Elliot, Paul R. Hunter

“…There was no apparent visual indication that correlations were especially poor during transition period from Delta to BA.1. …”
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Association of Risk-Taking Behaviors, Vestibular Provocation and Action Boundary Perception Following Sport-Related Concussion in Adolescents by Shawn R. Eagle, Anthony P. Kontos, Shawn D. Flanagan, Christopher Connaboy

“…The Vestibular Ocular Motor Screening (VOMS) tool is a brief screening tool designed to identify ocular or vestibular dysfunction following sport-related concussion, where horizontal/vertical vestibular ocular reflex (VOR) and visual motion sensitivity (VMS) are the primary vestibular outcomes. …”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Aim of the study: to reduce cognitive impairment during laparoscopic cholecystectomy by perioperative administration of drugs with antihypoxic and antioxidant effects under the control of stabilography.   Materials and methods. We studied the effect of general anesthesia and antioxidants on cognitive, static and locomotor functions during laparoscopic cholecystectomy. …”
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Accessibility of Massive Open Online Courses in Computer Sciences and Programming for Persons with Disabilities by E. A. Kosova, A S. Gapon, K. I. Redkokosh

“…At the same time, the specifics of online courses on programming require greater attention to the web content accessibility for persons with disabilities, especially in a program code.Material and methods. The selection of MOOCs was carried out in July 2020 by browsing catalogs of platforms with Russian-language content. …”
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A Prospective Observational Study on the Risk of Contrast-Induced Nephropathy Among Patients Undergoing Fundus Fluorescein Angiography by Niño Carlo M. Naidas, MD, Catherine E. Jordan, MD, Romulo N. Aguilar, MD, Arlene C. Crisostomo, MD

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Persistent cough after segmental resection, an issue that clinicians need to pay more attention to by He Guan, Zhijun Han, Qifei Wan, Qiangwen Huang, Li Wei, Jiwei Li

“…This study aims to explore the risk factors for persistent cough following pulmonary segmentectomy and to establish a predictive model to guide perioperative management.MethodsThis retrospective study included 540 patients who underwent thoracoscopic pulmonary segmentectomy at Zhengzhou University People’s Hospital from February 2024 to January 2025. …”
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Using musical pitch interval comparisons to assess cochlear implant frequency-to-place maps by Rebecca M. Lewis, Melanie L. Gilbert, Jordan A. Beim, Andrew J. Oxenham, Charles J. Limb

“…The present study seeks to develop a behavioral assessment metric for how well place-based pitch is represented across the frequency spectrum by evaluating the accuracy with which listeners perceive and compare pitch intervals across different frequency regions.MethodsThe study included two groups: normal-hearing (NH) listeners and CI recipients. …”
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Supramalleolar osteotomy outcomes for post-traumatic fracture-related ankle arthritis: a retrospective analysis by Yun-Qing Zhao, Xue-Wen Wang, Heng Li, Xiao-Feng Gong, Yong Wu

“…Abstract Background This study aimed to investigate the early-to-mid-term efficacy of supramalleolar osteotomy (SMO) for the management of post-traumatic ankle arthritis resulting from previous fractures. Methods A retrospective analysis was conducted on the clinical data of 19 individuals with post-traumatic ankle arthritis secondary to old fractures treated with SMO between March 2018 and September 2022. …”
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