Metformin inhibits pathological retinal neovascularization but promotes retinal fibrosis in experimental neovascular age-related macular degeneration by Xin Wang, Xin Wang, Xu Liang, Shiya Huang, Mingyan Wei, Yuan Xu, Xiaodong Chen, Yanliang Miao, Rongrong Zong, Xiang Lin, Shiying Li, Zuguo Liu, Zuguo Liu, Qian Chen, Qian Chen

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Swept-source optical coherence tomography features of choroidal tumors and tumor mimics: A 5-year retrospective study by Ruiheng Zhang, Yitong Li, Li Dong, Wenda Zhou, Wenbin Wei, Yueming Liu

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Assessing the neurological impact of vitamin B12 deficiency among the population of Riyadh, Saudi Arabia by Khalid A. Bin Abdulrahman, Abdulelah F. Alshehri, Faisal Marzouq Almutairi, Faisal Ali Almahyawi, Rayan Saleh Alzahrani, Osama Thamer Al-Ahmari, Khalid Alshammari, Turki Ahmed Aljuhani, Yazeed Yahya Alkadi, Mohammed Atiah Alisi

“…BackgroundVitamin B12 (cobalamin) deficiency can cause anemia, peripheral neuropathy, visual impairment and irreversible neurological damage. …”
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Regional homogeneity patterns reveal the genetic and neurobiological basis of State-Trait Anxiety by Yuanhao Li, Su Yan, Jia Li, Yuanyuan Qin, Li Li, Nanxi Shen, Yan Xie, Dong Liu, Jicheng Fang, Tian Tian, Wenzhen Zhu

“…However, the genetic and neurobiological basis of anxiety-related functional changes remain largely unknown. Methods Participants aged 18–30 from the community underwent resting-state fMRI and were assessed with the State-Trait Anxiety Inventory. …”
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Bibliometric mapping of diabetes mellitus and sarcopenia research: hotspots and emerging trends by Min Wang, Qiyang Zhou, Xinyu Guo, Xiaolong Cui, Zhongquan Tang, Ting Ou, Xiaomin Zhao, Chen Liang, Peiyu Xu, Xinyu Dai, Jingqing Yao, Guozhong Ji, Yuntao Li

“…This study pioneers a bibliometric analysis to systematically investigate their association, aiming to map the knowledge structure, evolutionary trajectories, current foci, and emerging frontiers within this area.MethodsWe retrieved 2,773 publications from the Web of Science Core Collection from inception until December 26, 2024, and visual analyses were conducted using CiteSpace, VOSviewer, R, and Microsoft Excel. …”
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AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen by Zhen Gao, Qiyuan Bai, Mingyu Wei, Hao Chen, Yan Yan, Jiahao Mao, Xiangzhi Kong, Yang Yu

“…The SHAP algorithm also provided clear explanations and visualizations of the model's predictions. …”
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The relationship between the CYP2C19*17 genetic polymorphism and the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome by V. Yu. Skryabin, M. S. Zastrozhin, E. A. Grishina, K. A. Ryzhikova, V. V. Shipitsyn, I. V. Barna, T. E. Galaktionova, A. S. Sorokin, E. A. Bryun, D. A. Sychev

“…The efficacy and safety assessment was performed using psychometric scales and scales for assessing the severity of adverse drug reactions: the Clinical Institute Withdrawal Assessment for Alcohol scale, the visual-analogue scale of the craving for alcohol, and the side-effect scale.Results. …”
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Development of a Recombinase Polymerase Amplification-Coupled CRISPR/Cas12a Platform for Rapid Detection of Antimicrobial-Resistant Genes in Carbapenem-Resistant <i>Enterobacterale... by Ji Woo Yang, Heesu Kim, Lee-Sang Hyeon, Jung Sik Yoo, Sangrim Kang

“…Traditional diagnostic methods are often too slow and complex for rapid point-of-care testing. …”
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Applying the blended KTA-Sprint framework to a usability assessment of a digital health module for informal caregivers co-managing heart failure by Ting Xiong, Camila Benmessaoud, Kaylen J. Pfisterer, Noor El-Dassouki, Raima Lohani, Karen Young, Quynh Pham

“…Scenario-based testing and multi-method analyses of user feedback allowed for triangulation of feedback. …”
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Thoracic duct drainage patterns in heterotaxy by Daniel A. Castellanos, Emily M. Bucholz, Katherine Bai, Jesse J. Esch, David Hoganson, Stephen P. Sanders, Raja Shaikh, Sunil J. Ghelani, David N. Schidlow

“…Results: Of 115 eligible patients, the terminal TD was visualized in 56 (49 %). The terminal TD was left-sided in 25 patients, right-sided in 29, and bilateral in two. …”
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Geospatial impact evaluation of a low-cost agricultural intervention for enhancing environmental resilience by Pratap Khattri, Rachel Sayers, Kunwar K. Singh, Ryan Slapikas, Chet Bahadur Tamang, Dinee Tamang, Brad Sagara, Ariel BenYishay

“…We assessed the causal impact of a program promoting sugarcane farming on its adoption and environmental outcomes, measured using multi-temporal satellite imagery, crop phenology, and clustering algorithms, along with machine learning and visual interpretation methods. Our results show that sugarcane adoption increased significantly in both treated and spillover communities, highlighting its potential as a sustainable agricultural practice. …”
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<i>Acinetobacter baumannii</i> Co-Resistant to Extended Spectrum Beta-Lactamases and Carbapenemases in Six Peruvian Hospital Centers by Mabel R. Challapa-Mamani, José Yareta, Alexander Fajardo-Loyola, Percy Asmat Marrufo, Carlos Peralta Siesquen, Jimena Pino-Dueñas, Henry Meza-Fernández, Jhony A. De La Cruz-Vargas, Pool Marcos-Carbajal

“…Objectives: The aim of this study was to describe the phenotypic and molecular characteristics of <i>Acinetobacter baumannii</i> isolates carrying resistance genes to beta-lactams and carbapenems in six Peruvian public hospital centers. Materials and methods: The susceptibility of bacterial isolates was determined using the automated MicroScan system, with interpretation according to the M100 S30 CLSI 2020. …”
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Deep learning empowered sensor fusion boosts infant movement classification by Tomas Kulvicius, Dajie Zhang, Luise Poustka, Sven Bölte, Lennart Jahn, Sarah Flügge, Marc Kraft, Markus Zweckstetter, Karin Nielsen-Saines, Florentin Wörgötter, Peter B. Marschik

“…These approaches are hardly comparable as all models are designed, trained and evaluated on proprietary/silo-data sets. Methods With this study we propose a sensor fusion approach for assessing fidgety movements (FMs). …”
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Trio-based whole-exome sequencing reveals mutations in early-onset high myopia by Ding Chen, Xiu-Feng Huang, Juan Huang, Yi-Ming Guo, Junhan Wei, Lu Ye, Yi-Xin Cai, Jiejing Bi, Fen-Fen Li

“…Purpose Myopia, especially high myopia (HM), represents a widespread visual impairment with a globally escalating prevalence. …”
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Robotic sympathetic trunk reconstruction for compensatory sweating after thoracic sympathectomyCentral MessageProspective by Lisa Wen-Yu Chen, MD, Tommy Nai-Jen Chang, MD, Chin-Pang Lee, MD, Cheyenne Wei-Hsuan Sung, MD, Chuan Cheng, MD, Kuo-Hsuan Chang, MD, PhD, Yin-Kai Chao, MD, PhD

“…A visual analog scale ranging from 0 to 10 (with 10 indicating the highest degree) was used to assess the severity of CS at different anatomical locations, thermoregulatory alterations, and gustatory hyperhidrosis. …”
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Identification of variants in SWI/SNF complex genes associated with neurodevelopmental disorders by Chen Liang, Chen Liang, Haihong Shi, Yanjuan Chen, Xia Wang, Jieyuan Jin, Liqun Su, Lijun Tang, Huihong Li, Fei Ling, Haoxian Li, Yanghui Zhang, Yanghui Zhang

“…ARID2, ARID1B, and SMARCC2 are important subunits of the SWI/SNF complex, and their variants can also result in Coffin-Siris syndrome (CSS), a type of NDDs characterized by CNS disorders, global developmental delay, visual/hearing impairment, distinct facial features, and congenital heart disease (CHD).MethodsThree NDDs families were recruited, and whole-exome sequencing and Sanger sequencing were used to detected their causative variant.ResultsWe described their symptoms and identified three variants of SWI/SNF complex genes unreported in disease cohorts, including a deletion variant of ARID2 (NM_152641: c.2901delC, p.Asn967LysfsX2), an insertion variant of ARID1B (NM_001374828: c.6532_6533insT, p.Trp2178LeufsX34), and a missense variant of SMARCC2 (NM_003075: c.2920C&gt;G, p.Pro974Ala). …”
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Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients by Jianming Xu, Kewen Zhou, Changzhen Fu, Chong-Bo Chen, Yaru Sun, Xin Wen, Luxi Yang, Tsz-Kin Ng, Qingping Liu, Mingzhi Zhang

“…Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass spectrometry (LC-MS) analysis to detect the oxylipins. …”
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The Micro-Structure of the Celiac Ganglia—A Two-Photon Microscopy Study on Parkinson’s Disease by Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Radu Hristu, George A. Stanciu, Adrian Tulin, Florin Filipoiu

“…Our research compares imaging results from TPM and SHG microscopy, visualizing neuronal integrity, collagen distribution, and the architectural organization of celiac ganglia. …”
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Multi-Channel Multi-Protocol Quantum Key Distribution System for Secure Image Transmission in Healthcare by Bandana Mallick, Priyadarsan Parida, Chittaranjan Nayak, Tarek Khalifa, Manoj Kumar Panda, Nawaf Ali, Gajanan Uttam Patil, Bibhu Prasad

“…The performance of the developed framework is tested via visual illustration and 11 different quantitative assessments. …”
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Large models in medical imaging: Advances and prospects by Mengjie Fang, Zipei Wang, Sitian Pan, Xin Feng, Yunpeng Zhao, Dongzhi Hou, Ling Wu, Xuebin Xie, Xu-Yao Zhang, Jie Tian, Di Dong, Yuanyuan Ji

“…This review summarizes the concepts, methods, and progress of large models in medical imaging, highlighting their potential in precision medicine. …”
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