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23661
Comparative analysis of a survey of outand inpatient physicians on secondary prevention of noncommunicable diseases
Published 2025-07-01“…Patients aged 60-64 years, regardless of sex, equally often seek outpatient and inpatient care. …”
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23662
Association between sleep disorders and subsequent heart failure
Published 2025-04-01“…Results: The study analyzed data from 123,516 patients with HF and an equal number of matched controls. The mean age of participants was 73.3–73.4 (SD 12.4) years, with 53.2% being women. …”
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23663
Lactiplantibacillus plantarum P101 Ameliorates TiO2 NP-Induced Bone Injury in Young Rats by Remodeling the Gut Microbiota and Inhibiting the Production of Pro-Inflammatory Cytokine...
Published 2024-11-01“…Lixin Xie,1,* Lihua Feng,1,* Xiaomin Tang,1 Yunping Xu,1 Hengyi Xu,2 Yang Liu1 1Department of Pediatrics, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, People’s Republic of China; 2State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hengyi Xu, State Key Laboratory of Food Science and Resources, Nanchang University, 235 Nanjing East Road, Nanchang, 330047, People’s Republic of China, Tel +0086-791-8830-4447-ext-9520, Fax +0086-791-8830-4400, Email kidyxu@163.com; HengyiXu@ncu.edu.cn Yang Liu, Department of Pediatrics, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1 minde Road, Nanchang, 330006, People’s Republic of China, Tel +86-791-8631-1209, Email ocean3166@yeah.netPurpose: To evaluate the therapeutic effect of oral administration of Lactiplantibacillus plantarum P101 (P101) on skeletal injury in young rats exposed to titanium dioxide nanoparticles (TiO2 NPs), and explore the potential mechanism.Methods: Four-week-old male rats were orally administration to TiO2 NPs and supplemented with P101 2 hours later for 4 weeks. …”
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23664
Current Advances and Challenges in CAR-T Therapy for Hematological and Solid Tumors
Published 2025-06-01“…This review aims to provide a comprehensive overview of the current landscape and future perspectives of CAR-T therapy in both hematological malignancies and solid tumors.Methods: A thorough literature search was conducted to identify relevant preclinical and clinical studies, as well as review articles, focusing on CAR-T therapy in various hematological malignancies and solid tumors. …”
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23665
Coilin Affects the Prognosis of Hepatocellular Carcinoma Through Cell Cycle and Apoptosis
Published 2025-02-01“…We investigated the diagnostic and prognostic value of COIL expression in HCC.Patients and Methods: This study evaluated the expression and prognostic significance of COIL using data from the TCGA and local hospital samples, with 374 and 118 liver cancer patients in the TCGA database and local hospital, respectively. …”
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23666
Effectiveness and Safety of Neoadjuvant Immunochemotherapy with and without Surgery in Patients with Resectable Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study
Published 2025-06-01“…Xuqiang Liao,1,* Xianshan Chen,1,* Wenyuan Hong,1,2,* Fengxia Chen,1 Gao Li,1 Liang Li1 1Department of Thoracic Surgery, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, People’s Republic of China; 2Hainan Medical University, Haikou, Hainan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gao Li, Email drligaokeyan@163.com Liang Li, Email nigoli@126.comBackground: This study aimed to retrospectively compare the effectiveness and safety of neoadjuvant immunochemotherapy with and without surgery for locally advanced esophageal squamous cell carcinoma (ESCC).Methods: This study included patients with ESCC who received neoadjuvant immunochemotherapy from May 2021 to July 2023. …”
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23667
Health-promoting behavior and its determinants towards non-communicable diseases among adult residents of the Gedeo zone, South Ethiopia: the application of the health belief model
Published 2024-09-01“…Statistically significant factors were declared at p-value of less than or equal to 0.05.ResultsThe overall means score for health-promoting behavior was 73.88 ± 16.79. …”
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23668
Enhanced hemodynamic stability and patient satisfaction with ciprofol-remifentanil versus propofol-remifentanil for sedation in shorter-duration fiberoptic bronchoscopy: a prospect...
Published 2025-05-01“…ObjectiveThis study aimed to compare the efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil in patients undergoing fiberoptic bronchoscopy (FOB).MethodsIn this prospective, randomized, double-blind, non-inferiority trial, 209 patients undergoing FOB were enrolled and equally divided into two groups (n = 106 each). …”
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23669
Cardiovascular risk factors in a treatment-naïve, human immunodeficiency virus-infected rural population in Dikgale, South Africa
Published 2014-12-01“…Biochemical parameters were tested using standard biochemical methods. HIV testing and CD4 counts were performed using the Alere Determine™ HIV 1/2 Ag/Ab kit and The Alere Pima™ Analyser. …”
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23670
Patient Interaction Phenotypes With an Automated SMS Text Message–Based Program and Use of Acute Health Care Resources After Hospital Discharge: Observational Study
Published 2025-07-01“…ObjectiveOur primary aim was to identify and characterize distinct patient interaction phenotypes with a postdischarge automated SMS text messaging program. MethodsThis was a secondary analysis of data from a randomized controlled trial that tested a 30-day postdischarge automated SMS text messaging intervention. …”
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23671
Impact of Subchorionic Hematoma on Pregnancy Outcomes in Obstetric Antiphospholipid Syndrome
Published 2025-03-01“…Rong Cang,1,* Xuelei Ding,1,* Zan Tian,2 Zijie Fu,3 Meijuan He,1 Ying Liang4 1Department of Gynecological Endocrinology, The Fourth Hospital of Shijiazhuang (Obstetrics and Gynecology Hospital Affiliated to Hebei Medical University), Shijiazhuang, Hebei, People’s Republic of China; 2Department of Dermatology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of China; 3Department of Gynecology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 4Department of Reproductive Medicine, The Fourth Hospital of Shijiazhuang (Obstetrics and Gynecology Hospital Affiliated to Hebei Medical University), Shijiazhuang, Hebei, 050011, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Liang, Email liangyly@126.comObjective: This study aimed to investigate the effects of subchorionic hematoma (SCH) in patients with obstetric antiphospholipid syndrome (OAPS) on pregnancy outcomes, as well as the clinical value of anticoagulant therapy.Methods: This retrospective study included 109 OAPS patients treated at the Fourth Hospital of Shijiazhuang from December 2019 to December 2021. …”
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23672
The effect of tactile versus auditory stimulation on reducing pain associated with invasive procedures among preterm neonates at NICUs
Published 2025-08-01“…The study hypothesized that preterm neonates who receive tactile stimulation will exhibit lower pain scores than those who receive auditory stimulation. Methods A comparative (three-group) quasi-experimental design included 90 preterm neonates divided equally into three groups (tactile stimulation group = 30, auditory stimulation group = 30, and control group = 30) at NICU affiliated with Beni-Suef University Hospital. …”
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23673
Focal Staphylococcus Aureus Septic Arthritis Elicits Age and TLR2-Dependent Periarticular Bone Loss
Published 2024-12-01“…While intra-articular injections of S. aureus LPPs induces local bone resorption in mice, the influence of aging and TLR2 expression on bone mineral density (BMD) after S. aureus bacteremia remains unclear.Methods: We analyzed distal femoral BMD in young and old TLR2 knock-out and wild-type mice following intravenous S. aureus infection. …”
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23674
Interleukin-6 as a Pan-Cancer Prognostic Inflammatory Biomarker: A Population-Based Study and Comprehensive Bioinformatics Analysis
Published 2025-01-01“…This study aimed to provide a comprehensive assessment of the prognostic value of IL-6 and its immunotherapeutic features using a population-based pan-cancer analysis and comprehensive bioinformatic analysis.Patients and Methods: In the cohort study, 540 patients were included to explore the prognostic value of serum IL-6 levels in cancer. …”
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23675
TyG-WC Index as a Superior Predictor of Hyperuricemia Risk in the Hypertensive Population: A Prospective Cohort Study
Published 2025-03-01“…Qin Zhang,1,* Jian Liu,2,* Ruize Zhang,3 Changfen Wang,4 Yanyan Song,5 Xi Wang,2 Fanling Zeng6 1Department of Cardiology, Xi Chang People’s Hospital, Xi Chang, Sichuan Province, 615000, People’s Republic of China; 2Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 3Dougherty Valley High School, San Ramon, CA, 94582, USA; 4Department of Cardiology, People’s Hospital of Qianxinan Prefecture, Guizhou Province, People’s Republic of China; 5Department of Endocrinology, Chongqing Jianshe Hospital, Chongqing, People’s Republic of China; 6Health Management Ctr, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xi Wang; Fanling Zeng, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, People’s Republic of China, Email 201884@cqmu.edu.cn; zengfanling@hospital.cqmu.edu.cnObjective: To evaluate the predictive value of the triglyceride-glucose waist circumference index (TyG-WC) for hyperuricemia (HUA) risk in the hypertensive population.Methods: This prospective cohort study involved 831 hypertensive patients with normal uric acid levels, who underwent continuous health examinations for five years. …”
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23676
Surgical outcomes of women undergoing radical resection of deep endometriosis of the sacral plexus: A prospective cohort study
Published 2025-01-01“…This study aims to report on the surgical outcomes in terms of pain and neurological symptom reduction in women undergoing surgical resection of SPE. Material and Methods Thirty premenopausal patients with histologically confirmed SPE who underwent surgical resection of the disease between 2018 and 2024 were included in this multicenter prospective analysis. …”
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23677
The impact of retail-sector delivery of artemether-lumefantrine on malaria treatment of children under five in Kenya: a cluster randomized controlled trial.
Published 2011-05-01“…This study in western Kenya aimed to evaluate the impact of providing subsidized artemether-lumefantrine (AL) through retail providers on the coverage of prompt, effective antimalarial treatment for febrile children aged 3-59 months.<h4>Methods and findings</h4>We used a cluster-randomized, controlled design with nine control and nine intervention sublocations, equally distributed across three districts in western Kenya. …”
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23678
Enhanced Antitumor Immunity Through T Cell Activation with Optimized Tandem Double-OX40L mRNAs
Published 2025-03-01“…This study investigates the use of mRNA-based cancer agents as promising tools to combat and reverse refractory TIME conditions.Methods: We optimized and engineered an mRNA cancer agent encoding double tandemly repeated sequences of the T cell costimulator Oxford 40 ligand (diOX40L). …”
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23679
Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells
Published 2016-04-01“…Jingya Li,1,* Ruizhen Zhao,1,* Xiaoli Li,1 Wenjun Sun,1 Miao Qu,1 Qisheng Tang,1 Xinke Yang,1 Shujing Zhang2 1Third Affiliated Hospital, 2School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing, People&rsquo;s Republic of China *These authors contributed equally to&nbsp;this work Background: Shen-Qi-Jie-Yu-Fang (SJF) is composed of eight Chinese medicinal herbs. …”
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23680
Type II diabetes mellitus risk assessment using FINDRISC questionnaire in systemic lupus erythematosus patients
Published 2020-11-01“…Abdominal obesity and intake of antihypertensive drugs were more often documented in SLE patients, while all other risk factors were equally represented in SLE and control groups. On average 3 [2; 5] risk factors were found in each SLE patient. …”
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