Study of the Chemical Composition and Anti-Inflammatory Mechanism of Shiyiwei Golden Pill Based on UPLC-Q-TOF/MS and Network Pharmacology by Han C, Chen J, Shen C, Liang Q, An Y, Zhou C, Liu K, Xia Q, He Q, Zhang H

“…This study aimed to investigate the chemical composition and anti-inflammatory effects of SYW, as well as its potential mechanisms.Methods: The components of SYW were identified using ultrahigh-performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS). …”
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Behavioral Changes During COVID-19 Omicron Variant Infection on Children with Autism Spectrum Disorder in China by Ye F, Hou X, Chen J, Qin H, Xu X, Liu D, Liu J, Sun Q, Liu H, Hu F, Zhou Y, Xu P, Zhang Q

“…Fang Ye,1,* Xiaonan Hou,1,* Jie Chen,1 Hui Qin,1 Xiaojing Xu,1 Die Liu,1 Jing Liu,2 Qi Sun,1 Haiyan Liu,3 Fang Hu,4 Yuwan Zhou,5 Pengfei Xu,1,* Qi Zhang1,* 1Department of Pediatrics, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 3Department of Pediatrics, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi an, People’s Republic of China; 4Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510623, People’s Republic of China; 5Department of Prevention Care, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Pengfei Xu; Qi Zhang, Department of Pediatrics, China-Japan Friendship Hospital, No. 2 East Yinghua Road, Chaoyang District, Beijing, 100029, People’s Republic of China, Email xpf@263.net; zhangqi0355@sina.comPurpose: The objective of this study was to investigate the behavioral changes in the core features and challenging behaviors of children with Autism Spectrum Disorder (ASD) during the COVID-19 Omicron wave (from December 2022 to January 2023) in China.Patients and Methods: A total of 515 caregivers of children with ASD completed an online survey. …”
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Prevalence and Molecular Characteristics of 16S rRNA Methylase Genes in Clinical Isolates of Carbapenem-Resistant Enterobacterales by Li C, Zhang F, Li G, Wang W

“…Caiyun Li,1,* Fa Zhang,1,* Gang Li,2,3 Wen Wang2,3 1Department of Clinical Laboratory, Nanjing Pukou People’s Hospital, Nanjing, 211800, People’s Republic of China; 2Center of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wen Wang, Email 42170662@qq.comObjective: To analyze the prevalence and molecular characteristics of 16S rRNA methylase genes in clinical isolates of carbapenem-resistant Enterobacterales, for clinical doctors provide a reference basis for the rational use of drugs.Methods: The Enterobacterales isolated from our hospital from 2020 to 2022 were selected and identified by VITEK 2 Compact automatic bacterial identification instrument. …”
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Assessing Racial and Gender Disparities in Asthma Education, Knowledge, and Healthcare Access Among Adolescents by Abballe A, Forman A, Jamet KE, Pant J

“…The goal is to identify gaps in asthma education and knowledge, as well as other barriers that may contribute to the underdiagnosis of asthma within these groups.Patients and Methods: This cross-sectional survey included adolescents aged 10– 18 years, with responses collected through Qualtrics. …”
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Level of physical activity of students from the police force academy in Bratislava by Gabriel Bujdos, Štefan Adamčák, Michal Marko, Anna Kozaňáková

“…The results of the questionnaire were later compared based on the participants gender and analysed using homogeneity test of two independent samples, two-sample t-test with equality and inequality of variances and the chi-square test at the level of significance p < 0.01 or p < 0.05. …”
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Compound Probiotics Improve Neuropathic Pain Prognosis in a Murine Model of Chronic Constriction Injury by Wang X, Chen Y, Qian S, Kong J, Su Z, Wang Q, Liao L

“…This study aimed to investigate the efficacy of compound probiotic treatment on neuropathic pain.Methods: Thirty mice were randomly divided into three groups: 1) sham group, 2) mouse with chronic constrictive injury (CCI), and 3) probiotic gavage with CCI (CCI+Prob). …”
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Effect of Outdoor Cycling, Virtual and Enhanced Reality Indoor Cycling on Heart Rate, Motivation, Enjoyment and Intention to Perform Green Exercise in Healthy Adults by Luca Poli, Gianpiero Greco, Michele Gabriele, Ilaria Pepe, Claudio Centrone, Stefania Cataldi, Francesco Fischetti

“…No significant differences were found between VRC and ERC in promoting intentions for outdoor activities, suggesting both technologies could be equally effective.…”
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Investigation of the Influence of Deletional and Non-Deletional Hemoglobin H Disease on Pregnancy Outcomes by Zhao KS, Pan QA, Yang HY, Su JY, Deng L

“…Kai Sun Zhao,1,&ast; Qiao Ai Pan,2,&ast; Hong Yan Yang,2 Jun You Su,2 Li Deng2 1Department of Obstetrics, The Second Nanning People’s Hospital (The Third Affiliated Hospital of Guangxi Medical University), Nanning, Guangxi, 530031, People’s Republic of China; 2Department of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Li Deng; Junyou Su, Department of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, No. 166, Daxuedong Road, Xixiangtang District, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +86 13877105871 ; +86 15277199813, Email dengli@gxmu.edu.cn; sujunyou@sr.gxmu.edu.cnObjective: The study aimed to provide clinical evidence regarding the perinatal management of HbH disease by comparing and analyzing blood routine, anemia characteristics, and their influence on pregnancy outcomes in patients with common deletional and non-deletional HbH disease at various pregnancy stages.Patients and Methods: From May 2017 to October 2023, a comparative analysis was conducted on pregnant women undergoing treatment at the Second Affiliated Hospital of Guangxi Medical University and the Second Nanning People’s Hospital. …”
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Stress, Cortisol, and Lipid Profiles Among Rwandan Undergraduate Students: A Cross-Sectional Study by Mushumba P, Uwineza DN, Nsanzimana V, Mapira HT, Gori E, Musarurwa C

“…This study aimed to investigate the relationship between serum cortisol levels, lipid profiles, and stress among undergraduate students at the University of Rwanda’s Huye Campus.Methods: A cross-sectional study recruited 247 undergraduate students using stratified sampling. …”
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Massa Medicata Fermentata treated spleen deficiency constipation by mediating intestinal microbiota and serum peptide by Kangxiao Guo, Kangxiao Guo, Yuan Tang, Tao Yang, Yongwang Yan

“…After the model was finished, CG was infused with 0.15 g/mL Massa Medicata Fermentata water infusion at a dose of 4 g/(kg·day), twice a day, at 0.4 mL. An equal amount of distilled water was infused in CC and CM for 7 days. …”
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Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow‐up in patients suffering from Ahlbäck III knee... by Shintaro Onishi, Christophe Jacquet, Hiroshi Nakayama, Jean Noël Argenson, Matthieu Ollivier

“…Conclusions OWHTO can provide outcomes equal to or better than UKA at 24 months post‐operatively in patients with advanced knee OA. …”
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The Pendulum of Adherence: An Interpretative Phenomenological Analysis of Psoriasis Treatment Discontinuation by Xiao Z, Jiang Y, Samah NA, Zhou H, Wang J

“…Frequent treatment discontinuation often results in disease recurrence and poorer health outcomes, highlighting the need for a comprehensive understanding of psoriasis patients&amp;rsquo; lived experiences concerning treatment adherence.Methods: A phenomenological research approach was employed to explore psoriasis patients&amp;rsquo; lived experiences concerning treatment adherence. …”
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Exploring Factors Influencing Dietary Management in Chinese Chronic Kidney Disease Patients Based on the COM-B Model: A Qualitative Study by Zhang N, Fan S, Wang S, Zhao Y, Liu H, Wei Y, Li Z, Wang W, Liu F

“…Given this knowledge gap, we aimed to explore the factors influencing dietary management in patients with chronic kidney disease based on the capability, opportunity, motivation, and behavior (COM-B) model and provide culturally suitable insights for the creation of focused interventions.Methods: Semi-structured interviews were conducted between September and November 2024 at the Department of Nephrology, Affiliated Central Hospital of Jiangnan University, with 45 participants, including 19 patients with chronic kidney disease, 10 caregivers, and 16 healthcare professionals. …”
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Synaptic Structure and Transcriptomic Profiling of Reward and Sensory Brain Areas in Male Mice of Fentanyl Addiction by Feng J, Xu N, Wang L, Wang H, Zhou Y, Shen Q

“…The side effects of fentanyl abuse have been well recognized, yet the underlying molecular adaptations across brain regions upon fentanyl exposure remain elusive.Methods: The transmission electron microscopy (TEM) and next-generation RNA-sequencing (RNA-seq) were used to investigate the ultrastructure synaptic alterations and transcriptional profiling changes of reward and sensory brain regions in mice after fentanyl exposure.Results: The naloxone-precipitated acute withdrawal symptoms were observed in mice exposed to fentanyl. …”
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Causal Associations Between Sleep Traits and Delirium: A Bidirectional Two-Sample Mendelian Randomization Study by Liu H, Zhang Z, He Y, Ding L, Wu T, Wang Y, Ma W

“…This bidirectional two-sample Mendelian randomization (MR) study was conducted to examine the possible causal relationships between sleep traits and delirium.Patients and Methods: Utilizing genome-wide association studies (GWAS), we identified ten sleep traits: chronotype, sleep duration, short sleep duration, long sleep duration, daytime napping, daytime sleepiness, insomnia, number of sleep episodes (NSE), sleep efficiency, and rapid eye movement sleep behavior disorder (RBD). …”
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In Vitro Fertilization and Dichorionic-Diamniotic Twin Pregnancies in Nulliparous Women: A Retrospective Cohort Study Comparing Pregnancy Outcomes Between Advanced and Younger Mate... by He MP, Jian WQ, Yuan CL, He SM, He MR, Yan J, Huang JC, Zhao KS

“…Mei Ping He,&amp;ast; Wen Qian Jian,&amp;ast; Chun Lan Yuan, Shi Mei He, Mei Rong He, Jian Yan, Jian Chun Huang, Kai Sun Zhao Department of Obstetrics, The Third Affiliated Hospital of Guangxi Medical University, The Second Nanning People’s Hospital, Nanning, Guangxi, 530031, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Kai Sun Zhao, Department of Obstetrics, The Third Affiliated Hospital of Guangxi Medical University, The Second Nanning People’s Hospital, No. 13, Dancun Road, Jiangnan District, Nanning City, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +86 13737085418, Email 339609234@qq.com Jian Chun Huang, Department of Obstetrics, The Third Affiliated Hospital of Guangxi Medical University, The Second Nanning People’s Hospital, No. 13, Dancun Road, Jiangnan District, Nanning City, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +86 13207801809, Email huangjc3081@163.comObjective: To compare pregnancy outcomes between advanced maternal age (AMA, ≥ 35 years) and younger maternal age (YMA, 20– 34 years) nulliparous women with IVF-conceived dichorionic-diamniotic (DCDA) twin pregnancies.Methods: We conducted a retrospective analysis on 141 nulliparous women undergoing cesarean delivery at The Second Nanning People’s Hospital (2020– 2024). …”
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Co-Assembled Nanoparticles Comprising Sorafenib and Hederagenin Derivative for Enhanced Anti-Hepatic Fibrosis Activity by Lu M, Dai Z, Lin Y, Sun C, Li S, Guo Z, Liu Y, Liu X, Li S, Liu R, Xu B, Lei H

“…Recent findings suggest that targeting the STING signaling pathway may provide an alternative strategy for slowing the progression of fibrosis.Methods: We synthesized liver-targeted co-assembled SHG nanoparticles (SHG NPs) that incorporate sorafenib and a hederagenin derivative (Hed), which acted as a STING pathway inhibitor. …”
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The Evaluation of Reference Values of Plasma and Effect-Site Concentrations of Propofol and Remifentanil During Extubation in Patients Who Had Hysteroscopy Procedures by Wei Y, Wang J, Xu Z, Ma R

“…Yu Wei,1– 3,&ast; Jianwei Wang,1– 3,&ast; Zifeng Xu,1– 3 Rui Ma1– 3 1Department of Anesthesiology, the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, Peoples Republic of China; 3Shanghai Municipal Key Clinical Specialty, Shanghai, Peoples Republic of China&ast;These authors contributed equally to this workCorrespondence: Rui Ma; Zifeng Xu, Department of Anesthesiology, the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai Municipal Key Clinical Specialty, Huashan Road 1961, Shanghai, 200030, People’s Republic of China, Tel +86-021-64070434, Email marui_merrygood@163.com; xuzf@shsmu.edu.cnAim: This study aimed to assess the correlation of plasma concentration (Cp) and effect-site concentration (Ce) of propofol and remifentanil with level of consciousness and evaluate their reference values during extubation in patients scheduled day-case operative hysteroscopy under propofol-remifentanil anesthesia.Methods: Propofol (Marsh model) and remifentanil (Minto model) were simultaneously administered using a target-controlled infusion (TCI) pump for the induction and maintenance of anesthesia. …”
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Association Between High-Sensitivity C-Reactive Protein Trajectories and the Incidence of Metabolic Syndrome:A Retrospective Cohort Study by Pan J, Cai X, Chen J, Xu M, Hu J, Mao Y, Chen T, Li L, Jin M, Chen L

“…JianJiang Pan,1,&ast; XiXuan Cai,1,&ast; JieRu Chen,1 MingYing Xu,1 JingYu Hu,1 YueChun Mao,1 Tao Chen,2 LuSha Li,1 MengQi Jin,1 LiYing Chen1 1Department of General Practice, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310020, People’s Republic of China; 2Department of General Practice, Jianqiao Community Health Service Center, Hangzhou, Zhejiang, 310021, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: LiYing Chen, Department of General Practice, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China, Email 3197020@zju.edu.cnPurpose: Understanding the role of systemic inflammation in the development of Metabolic Syndrome (MetS) is crucial for identifying individuals at a higher risk of this cluster of conditions that increase the risk of heart disease, stroke, and diabetes.Patients and Methods: A retrospective cohort study was conducted with 4,312 participants who were free from MetS at the study’s onset and had high-sensitivity C-reactive protein (hsCRP) levels measured. …”
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Clinical and Microbiological Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Associated Recurrent Urinary Tract Infections by Cao H, Cheng H, Zhou J, Zhao J, Xu M, Fei Y

“…Investigating its features in rUTIs may provide insights into effective prevention strategies.Methods: We analyzed a cohort of patients with rUTIs caused by Klebsiella pneumoniae from April 2020 to April 2024. …”
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