Identification of Ferroptosis -Related Genes in MAFLD/MASH and HQHF Validation by Liu S, Zhang L, Xu J, Zhao Q, Shang D, Liu X, Zhang Q, Liu M, Zhao W

“…This study aims to identify differentially expressed genes (DEGs) associated with MAFLD/MASH and explore their potential link to ferroptosis, a form of regulated cell death.Methods: We conducted differential expression analysis using two datasets from the GEO database. …”
Get full text

The Adjunctive Effect of Quercetin on Postoperative Pain Management Following Cesarean Section: A Randomized Controlled Study by Mohamed Elmokadem E, Khaled Abou El Fadl D, Bassiouny AM, Mahmoud MMAE, Samy M, El Said NO

“…The primary outcome was postoperative pain intensity assessed using a 10 cm Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours after surgery. …”
Get full text

The Different Immune Response Between Onset and Remission of AQP4 Antibody-Positive Optic Neuritis Based on RNA Sequencing of Whole Blood by Shi R, Luo Y, Chen Y, Chen X, Li S, Chen Z, Wang K, Zou W

“…Ruohan Shi,1,* Yidan Luo,2,3,* Yusheng Chen,1,2,* Xuelian Chen,4 Shiyi Li,5 Ziqing Chen,1 Ke Wang,6,7 Wenjun Zou1,2 1Department of Ophthalmology, Wuxi No.2 People’s Hospital, Jiangnan University Medical Center(JUMC), Wuxi, Jiangsu, People’s Republic of China; 2Department of Ophthalmology, Affiliated Wuxi Clinical College of Nantong University, Wuxi, Jiangsu, People’s Republic of China; 3Department of Comprehensive Ophthalmology, Wuhan Bright Eye Hospital, Wuhan, Hubei, People’s Republic of China; 4Department of Ophthalmology, PuNan Branch of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 5Department of Ophthalmology, Jingjiang People’s Hospital Affiliated to Yangzhou University, Taizhou, Jiangsu, People’s Republic of China; 6National Health Commission (NHC) Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, People’s Republic of China; 7Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenjun Zou, Department of Ophthalmology, Wuxi No.2 People’s Hospital, Jiangnan University Medical Center (JUMC), Wuxi, Jiangsu, People’s Republic of China, Tel +86-510-6856-3091, Fax +8668562052, Email wenjunzou2022@163.comPurpose: We aimed to investigate differences in the immune response between the onset and remission phases of AQP4 antibody-positive optic neuritis (AQP4-ON).Methods: Whole blood samples were collected from 7 healthy volunteers, 6 patients with AQP4-ON in the acute phase and 6 patients with AQP4-ON in the remission phase. …”
Get full text

Clinical Efficacy of Acupuncture in the Treatment of Uterine Contraction Pain Post-Cesarean Section: Protocol of a Randomized Controlled Trial by Deng Y, Li Z, Zhang T, Tang X, Luo Y, Li Q, Zhang S, Liu Z, Tang D, Ai Z, Guo T, Liang F

“…This study uses acupuncture as an intervention and aimed to provide strong evidence for the clinical efficacy of acupuncture in treating UCPCS.Patients and Methods: This single-blind, randomized controlled trial (RCT) was conducted at the Ludian County Hospital of Traditional Chinese Medicine, China. …”
Get full text

The results of investigating the efficacy and safety of non-medical switching from the original rituximab to its biosimilar in rheumatoid arthritis patients (AMBIRA study) by M. A. Korolev, Yu. B. Ubshaeva, N. Y. Banshchikova, E. A. Letyagina, A. A. Mullagaliev

“…They were switched to equal-dose biosimilar (Acellbia®) by non-medical reasons and were observed throughout the year. …”
Get full text

Integrating Deep Learning and Radiomics in Differentiating Papillary Thyroid Microcarcinoma from Papillary Thyroid Carcinoma with Ultrasound Images by Yu B, He H, Zheng Q, Ai Y, Yu X, Li S, Zhang J, Jin J, Jin X, Yu W

“…Bing Yu,1,2,* Huijuan He,3,* Qiao Zheng,2,* Yao Ai,2 Xianwen Yu,2 Sunjun Li,4 Ji Zhang,2 Juebin Jin,5 Xiance Jin,2,6 Wenliang Yu3 1Purchasing Center Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310020, People’s Republic of China; 2Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 3Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China; 4Alberta College, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 5Medical Engineering Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 6School of Basic Medical Science, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiance Jin, Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China, Email jinxc1979@hotmail.com Wenliang Yu, Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China, Email wlyu1982@aliyun.comPurpose: The feasibility and accuracy of ultrasound-based radiomics, deep learning, and combined deep learning radiomics models were investigated in the differentiation of papillary thyroid carcinoma and papillary thyroid microcarcinoma to decrease the risk of overtreatment of papillary thyroid microcarcinoma.Methods: A total of 549 patients with confirmed 180 papillary thyroid carcinoma and 436 papillary thyroid microcarcinoma nodules from Hospital One were enrolled and randomly divided into training and validation cohorts at a ratio of 8:2 with 56 patients left as independent testing set 1. …”
Get full text

Predicting Short-Term Risk of Cardiovascular Events in the Elderly Population: A Retrospective Study in Shanghai, China by Zhu W, Tan S, Zhou Z, Zhao M, Wang Y, Li Q, Zheng Y, Shi J

“…This study aimed to develop a short-term risk prediction model for CVD events among individuals aged ≥ 60 years in Shanghai, China.Methods: Stratified random sampling recruited elderly individuals. …”
Get full text

GenECG: a synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development by Neil Bodagh, Steven Niederer, Mark O’Neill, Rachel Burns, Darwon Rashid, Steven E Williams, Miguel O Bernabeu, Ali Gharaviri, Vinush Vigneswaran, Magda Klis, Irum Kotadia, Malihe Javidi, Kyaw Soe Tun, Adam Barton

“…Objectives An image-based ECG dataset incorporating visual imperfections common to paper-based ECGs, which are typically scanned or photographed into electronic health records, could facilitate clinically useful artificial intelligence (AI)-ECG algorithm development. …”
Get full text

Profiling Language Skills in Minimally Verbal Autism: Findings From Greek-Speaking Preschoolers by Eleni Peristeri, Maria Andreou

“…Interventions that draw on semantic scaffolding and incorporate visual aids—such as picture-based communication tools—seem to be a promising approach to implement language treatment programs for the specific population. …”
Get full text

Perceptual-Motor Abilities and Reversal Frequency of Letters and Numbers in Children Diagnosed with Poor Reading Skills by Danjela Ibrahimi, Marcos Aviles, Juvenal Rodríguez-Reséndiz

“…Purpose: This paper investigated the visual–perceptual and visual–motor skills and the reversal frequency of letters and numbers that mirror one another in one hundred children aged 6–13 years diagnosed with poor reading skills. …”
Get full text

Elevation of ANXA1 associated with potential protective mechanism against ferroptosis and immune cell infiltration in age-related macular degeneration by Jing Chen, Tu Lu, Chen Chen, Wenbin Zheng, Lin Lu, Naiyang Li

Get full text

Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial by Shoko Kondo, MD, Yoshiko Okano, MD, PhD, Satoshi Iraha, MD, PhD, Shoji Tokunaga, PhD

“…Purpose: Neurotrophic keratopathy is part of the leprosy sequelae and causes progressive deterioration of visual acuity. Although leprosy is bacteriologically curable, there is currently no efficient treatment. …”
Get full text

Effect of Forbrain Cognitive Training Intervention Prescriptions Based on Risk Factors on Patients with Cognitive Impairment After Traumatic Brain Injury by ZHANG Xueru, WANG Hongbin, CUI Huiying, HAO Xijun, CHEN Changxiang

“…ObjectiveTo observe the effect of Forbrain cognitive training intervention prescriptions based on risk factors on cognitive function and activities of daily living in patients with cognitive impairment after traumatic brain injury (TBI).MethodsA total of 120 patients with cognitive impairment after TBI treated in Tangshan Workers' Hospital from October 2021 to May 2022 were randomly divided into control group, observation group 1 and observation group 2 according to Excel random function, with 40 cases in each group. …”
Get full text

Hydrophobic and Hydrophilic IOLs in Patients with Uveitis – A Randomised Clinical Trial by Pålsson S, Schuborg C, Sterner B, Andersson Grönlund M, Zetterberg M

“…Sara Pålsson,1,2 Claes Schuborg,2,3 Bertil Sterner,1,2 Marita Andersson Grönlund,1,4 Madeleine Zetterberg1,2 1Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 2Region Västra Götaland, Sahlgrenska University Hospital, Department of Ophthalmology, Mölndal, Sweden; 3Guldhedskliniken, Gothenburg, Sweden; 4Department of Ophthalmology, Faculty of Medicine and Health, Örebro University, Örebro, SwedenCorrespondence: Madeleine Zetterberg, Sahlgrenska University Hospital, Department of Ophthalmology, Mölndal, SE 431 80, Sweden, Tel +46 31 33 43 31 50, Fax +46 31 41 29 04, Email madeleine.zetterberg@vgregion.sePurpose: To compare inflammatory response, visual acuity, and complications of two intraocular lenses (IOLs) in patients with and without uveitis.Setting: Tertiary referral centre at Sahlgrenska University Hospital/Mölndal, Sweden.Design: Prospective randomised controlled trial.Patients and Methods: Patients with and without uveitis eligible for cataract surgery were randomised to receive a hydrophobic or a hydrophilic square-edged intraocular lens (IOL). …”
Get full text

Appropriate Use of Transesophageal Echocardiogram for Infective Endocarditis: A Single Center Experience by Robby Singh, Moumita Naidu, Yousef Bader, David Freeman, Marcel Zughaib

“…Transesophageal echocardiogram (TEE) is a valuable tool in healthcare today with its ease of use, ability to visualize important structures not seen on transthoracic echocardiogram (TTE), and the relatively lower cost of TEE, high yield, and no significant radiation exposure. …”
Get full text

Functional and Anatomical Outcomes of Faricimab in Previously Treated Wet Age-Related Macular Degeneration: Systematic Review and Pooled Analysis by Ali Khodor, Jonathan T. Caranfa, Tavish Nanda, Raul E. Ruiz-Lozano, Manuel E. Quiroga-Garza, Stephanie Choi, Ali Chehab, Eugenia M. Ramos-Dávila, Jeffrey S. Heier, Chirag P. Shah, Andre J. Witkin

“…Methods The PubMed, Embase, and Google Scholar databases were searched for studies reporting outcomes of treatments for previously treated cases of wAMD. …”
Get full text

Identification of a Novel Subtype of Ocular Hypertensive Eyes with the Lowest Risk of Progression Under Treatment by Asma Poursoroush, Vida Abedi, Xiaoqin Huang, Jiang Li, Alireza Vafaei Sadr, Amy L. de Jongh Curry, Louis R. Pasquale, Michael V. Boland, Chris A. Johnson, Siamak Yousefi

“…We developed principal component analysis (PCA), t-distributed stochastic neighbor embedding (t-SNE), and unsupervised density-based clustering, then applied to the baseline visual fields (VFs) to identify different clusters of eyes. …”
Get full text

Results of rehabilitation of myasthenia gravis patients with subclinical respiratory disturbances by Yu. N. Rushkevich, O. V. Galievskaya, M. P. Mozheyko, S. A. Likhachev

“…To analyze the effectiveness of rehabilitation of MG patients with subclinical respiratory disturbances, to determine the level of fatigue in MG, to assess the effect of physical activity on fatigue.Materials and methods. The fatigue was studied in 53 MG patients using visual analog scale, “Well-being, activity, mood” questionnaire and fatigue assessment scale. …”
Get full text

Five-year Outcome of Aflibercept Administration with “Treat and Extend” for Neovascular Age-Related Macular Degeneration by Wada I, Oshima Y, Fukuda Y, Shiose S, Kano K, Ishikawa K, Nakao S, Kaizu Y, Hasegawa E, Kannan R, Ishibashi T, Sonoda KH

“…Although it subsequently declined, it sustained the initial visual acuity. The average macular thickness (CMT) was significantly reduced and maintained throughout the follow-up period. …”
Get full text

Comparison of Intravitreal Dexamethasone Implant and Ranibizumab in Vitrectomized Eyes with Diabetic Macular Edema by Jia-Kang Wang, Tzu-Lun Huang, Pei-Yao Chang, Wei-Ting Ho, Yung-Ray Hsu, Fang-Ting Chen, Yun-Ju Chen

“…This retrospective study aimed to compare the efficacy of intravitreal ranibizumab (IVR) and intravitreal dexamethasone implant (IDI) for pseudophakic vitrectomized eyes with diabetic macular edema (DME) in a single institution. Methods. Pseudophakic vitrectomized eyes with treatment-naïve center-involved DME were enrolled, with one eye in each patient. …”
Get full text