Blood Eosinophil Count in Asthma Is Associated With Increased Abdominal Aortic Diameter and Increased Vascular Stiffness by Biener L, Budimovska A, Skowasch D, Pizarro C, Frisch BC, Nickenig G, Stumpf MJ, Schaefer CA, Schahab N

“…Blood eosinophil count (BEC) is implicated in both eosinophilic asthma and arterial wall inflammation.Objective: To explore the possible association of BEC in asthma and abdominal aortic artery changes.Methods: 112 outpatients were prospectively enrolled in this exploratory study. …”
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Effects of mini-dose esketamine–dexmedetomidine combination supplemented intravenous analgesia on postoperative sleep quality in elderly patients after total knee arthroplasty: a p... by Xiaoyan Wang, Xiaoli Ji, Jinfeng Liu, Caicai Liu, Yanhua Luo

“…However, the effectiveness of mini-dose esketamine–dexmedetomidine supplemented intravenous analgesia on postoperative sleep quality remains to be elucidated.Methods and analysis 110 elderly patients undergoing total knee arthroplasty will be randomly assigned to different regimens of patient-controlled intravenous analgesia with a total volume of 100 mL in either the experimental group (sufentanil 1.5 µg/kg+esketamine 25 mg+dexmedetomidine 100 µg) or the control group (sufentanil 1.5 µg/kg+equal vol of placebo, ie, saline). …”
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Effective Dosage of Ciprofol for the Induction of General Anesthesia Across Diverse Age Groups in Adults: A Single-Center, Prospective, Non-Randomized Sequential Trial by Deng L, Zhang C, Tan M, Zeng W, Luo G, Li P

“…This study aims to determine the optimal dosage of ciprofol for inducing general anesthesia in adult patients of different ages and its correlation with Narcotrend index (NTI).Patients and Methods: 105 patients were stratified into three age groups: 18– 40 (Group A), 41– 65 (Group B), and 66– 85 (Group C) years. …”
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Nanotherapeutics for Macrophage Network Modulation in Tumor Microenvironments: Targets and Tools by Li R, Huang J, Wei Y, Wang Y, Lu C, Liu J, Ma X

“…In conclusion, nanotherapeutics targeting macrophages remains immense potential for the development of macrophage-mediated tumor treatment methods and will further enhance our understanding, diagnosis, and treatment of various malignants.Keywords: engineered macrophages, nanomedicine, cancer therapy, anti-tumor immunity…”
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The Application and Efficacy of Medication Safety Officer-Based Multidisciplinary Management in Reducing Adverse Drug Reaction and Improving Intravenous Management by Zhang X, Yan M, Qu X, Li Y, Liu L, Liu C

“…This study evaluates the effectiveness of medication safety officer (MSO)-based multidisciplinary management on managing IV fluids in children’s outpatient and emergency departments, aiming to reduce adverse drug reaction (ADR) and standardize IV infusion management.Methods: Implementing MSO-based multidisciplinary management integrates multidisciplinary supervision, information system optimization, and fostering medication safety culture. …”
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Using a Systems Thinking Approach to Increase Coastal Community Resilience against Environmental Shocks: A Case Study of Valiathura Coastal Area, India by Baker Matovu, Meltem Alkoyak-Yildiz, Isaac Lukambagire, Linda A. Etta, Yasin Bbira, Expedito Nuwategeka

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Hippocampal Anti-inflammatory Effect of Electroacupuncture at Baihui and Shenting on Cognitive Dysfunction Induced by Systemic Inflammation by CHEN Xiaomei, PANG Lina, WANG Zhifu

“…ObjectiveTo investigate the hippocampal anti-inflammatory mechanism of electroacupuncture at Baihui and Shenting on cognitive dysfunction induced by Lipopolysaccharide (LPS) intraperitoneal injection.MethodsA total of 45 clean grade adult C57BL/6 male mice (bodyweight 18-22 g) were randomly divided into control group, endotoxic brain injury group (model group) and endotoxic brain injury + electroacupuncture group (EA group). …”
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The sero-prevalence of brucellosis in cattle and their herders in Bahr el Ghazal region, South Sudan. by Nuol Aywel Madut, Adrian Muwonge, George William Nasinyama, John Bwalya Muma, Jacques Godfroid, Ambrose Samuel Jubara, James Muleme, Clovice Kankya

“…The bovine sero-prevalence was approximately equally distributed among the male 30.4% (26.9-34.2) and the females 32.5% (26.8-38.7). …”
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Comparison of Learning Curves and Clinical Outcomes in Unilateral Biportal Endoscopic Spinal Surgery Versus Percutaneous Transforaminal Endoscopic Surgery: A Cumulative Sum Analysi... by Yuan S, Chen R, Mei Y, Fan N, Wang T, Wang A, Du P, Xi Y, Zang L

“…This study aimed to evaluate the learning curves for unilateral biportal endoscopic spinal surgery (UBESS) and percutaneous transforaminal endoscopic surgery (PTES) by performing cumulative sum (CUSUM) analysis and to assess their efficacies in managing degenerative spinal diseases.Patients and Methods: This retrospective cohort study included 100 consecutive patients who underwent PTES and 100 consecutive patients who received UBESS. …”
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Effect of oral health education model on tooth brushing behavior and oral hygiene among children with intellectual disabilities by Muhammad Fiqih Sabilillah, Hari Kusnanto, Lisdrianto Hanindriyo, Sri Kuswandari

“…A total of 52 children were recruited, divided equally into two groups: 26 in the intervention group and 26 in the control group, taken from September 02 to October 11, 2024. …”
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A safety review and meta-analyses of bevacizumab and ranibizumab: off-label versus goldstandard. by Christine Schmucker, Christoph Ehlken, Hansjuergen T Agostini, Gerd Antes, Gerta Ruecker, Monika Lelgemann, Yoon K Loke

“…<h4>Background</h4>We set out a systemic review to evaluate whether off-label bevacizumab is as safe as licensed ranibizumab, and whether bevacizumab can be justifiably offered to patients as a treatment for age-related macular degeneration with robust evidence of no differential risk.<h4>Methods and findings</h4>Medline, Embase and the Cochrane Library were searched with no limitations of language and year of publication. …”
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Comparative study between the roles of intrauterine misoprostol versus the sublingual route for prevention of postpartum blood loss in elective cesarean sections: a randomized cont... by Adel Atef, Hadeer Salah Eldin Abdelrahman Mohamed Shehata, Yasmin Ahmed Bassiouny, Hesham Gaber Al-Inany

“…Objectives To assess the value of adding intrauterine misoprostol together with intravenous oxytocin injection compared with sublingual misoprostol together with intravenous oxytocin injection during elective cesarean section to reduce blood loss intraoperatively and prevent postpartum hemorrhage. Methods A total of 192 pregnant women were counseled and recruited from the labor and delivery unit at Kasr Al Aini Hospital, Cairo University, and equally randomized into two groups. …”
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Real-world results of the Zeiss selective laser trabeculoplasty in adult South African primary open-angle glaucoma patients by Brian Church, Pierre Wassermann

“…At 6 months, 69.3% of patients maintained IOP lower than or equal to pre-procedure IOP on fewer medications compared to baseline. …”
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Associations of Dietary Live Microbes Intake and Prevalence of Prediabetes in US Adults: A Cross-Sectional Analysis by Ge X, Du J, Wang J, Xi L, Gao J, Zhou P, Peng W, Huang S

“…We aimed to elucidate the associations between dietary intake of live microbes and the risk of prediabetes.Methods: Adult participants from the 1999– 2018 US National Health and Nutrition Examination Survey were included and categorized into the low, medium, and high live microbe intake groups based on the Sanders classification system. …”
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Using siRNA-Based Anti-Inflammatory Lipid Nanoparticles for Gene Regulation in Psoriasis by Zeng A, Liu Y, Wang P, Cao Y, Guo W

“…Aizhong Zeng,&ast; Yuanyuan Liu,&ast; Ping Wang, Yufei Cao, Wei Guo School of Life Science and Technology, China Pharmaceutical University, Nanjing, 211112, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Wei Guo, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 211112, People’s Republic of China, Email guowei1205@cpu.edu.cnBackground: Psoriasis is a chronic inflammatory autoimmune disease, yet it affects hundreds of millions of people. …”
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Scenarios of passive particle transport in the velocity field of a vortex pair in shear flow by Govorukhin, Vasily Nikolaevich, Goncharov, Boris Konstantinovich

“…Scenarios of particle transport and mixing are studied depending on the intensity of one vortex (in the region of [-1, 1]∖{0}) and various shear flows with fixed initial positions of the vortices and an intensity of the second equal to unity. In the investigation, we mainly use numerical methods of dynamical systems analysis. …”
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Prevalence of Insomnia and Related Factors Among Cancer Outpatients in China by Zhao K, Yu Z, Wang Y, Feng W

“…This study aims to investigate insomnia in cancer patients and further analyze potentially related factors.Methods: Oncology outpatients treated at Fudan University Shanghai Cancer Center were consecutively recruited. …”
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Comparison of Surface Roughness of Conventional and Epoxy-coated Stainless Steel Arch Wires in Monocrystalline Ceramic Bracket and Stainless-Steel Bracket by Mohammed Ismail Almashhdani, Saeed Al-Samak

“…The two types of arch wires were slid on two types of brackets of premolars of slot size 0.022x0.030″ roth prescription (n=36) divided equally into monocrystalline sapphire clear aesthetic ceramic brackets (CB) and Razor stainless steel bracket (SSB). …”
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Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau by WANG Zhenliang, CHEN Manyu, ZHAO Jianlin, YUAN Ke, YANG Jie, ZHANG Chen

“…[Objective] Empirical rainfall thresholds have geographical limitations, it is of great significance to carry out a rainfall threshold modeling study for landslide hazard on the Chinese Loess Plateau. [Methods] Taking the Yanhe River Basin on the Loess Plateau as the research area, the landslide identification of the Yanhe River Basin based on InSAR was carried out by integrating Sentinel-1A, DEM, GPM rainfall and other multi-source data. …”
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Prediction model for the selection of patients with glioma to proton therapy by Jesper Folsted Kallehauge, Siri Grondahl, Camilla Skinnerup Byskov, Morten Høyer, Slavka Lukacova

“…Interpretation: Logistic regression and SVM using age and CTV performed equally well and achieved a very high positive predictive value. …”
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