Endoscopic Treatment of Zenker’s Diverticulum: Comparable Treatment Outcomes in Treatment-Naïve and Pretreated Patients by Johannes Manzeneder, Christoph Römmele, Carolin Manzeneder, Alanna Ebigbo, Helmut Messmann, Stefan Karl Goelder

“…Patients with ZD can be treated safely and effectively with the sb knife jr. Retreatment leads to equal symptom relief as compared to a successful first-line treatment and is not associated with a higher rate of adverse events.…”
Get full text

Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report by Weng D, Zhou H, Huang G, Cao Q, Wang H, Cao Z, Xie Q

“…Early diagnosis and precise management are essential for improving outcomes, given the limitations of traditional microbiology detection methods in identifying the causative pathogens.Case Presentation: A 68-year-old immunocompetent male presented with recurrent fever, fatigue, loss of appetite and initial evidence of sepsis and AKI upon admission. …”
Get full text

Influence of trust on the acceptance of the RTS,S malaria vaccine in the Kassena-Nankana districts of Ghana by Eustace Bugase, Paulina Tindana

“…Documented evidence such as the boycott of the oral polio vaccine in northern Nigeria and the failure of the Ebola vaccine trial in Ghana among others highlight the impact of public trust on vaccine acceptance. Methods This is an explorative cross-sectional mixed-method study conducted in the Kassena Nankana districts. …”
Get full text

Correlation Between Bone Metabolism Indices and Osteoporotic Thoracolumbar Vertebrae Fracture in Postmenopausal Women by Jing P, Kong F, Meng B, Yang S

“…Pengrui Jing,* Fanqi Kong,* Bin Meng, Shaofeng Yang Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, 215006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shaofeng Yang; Bin Meng, Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou, Jiangsu, 215006, People’s Republic of China, Email shaofengyang1014@163.com; mengbinspine@163.comBackground: This study aims to explore the correlation between bone metabolism indices and osteoporotic thoracolumbar vertebrae fracture (OTVF) in postmenopausal women.Methods: A total of 447 female patients with postmenopause and underwent OTVF in our hospital were selected as group A. …”
Get full text

Comparison of Canal Transportation, Separation Rate, and Preparation Time between One Shape and Neoniti (Neolix): An In Vitro CBCT Study by Maryam Kuzekanani, Faranak Sadeghi, Nima Hatami, Maryam Rad, Mansoureh Darijani, Laurence James Walsh

“…The teeth were divided into two equal groups (n = 20), and the canals were cleaned and shaped using either Neoniti™ or One Shape™ engine-driven NiTi rotary files. …”
Get full text

Taxus chinensis-Derived Nanovesicles Alleviate Mouse Colitis by Inhibiting Inflammatory Cytokines and Restoring Gut Microbiota by Gong Q, Hu J, Pu C, Zhao Z, Guo Y

“…Among these, plant-derived nanovesicles (NVs) have garnered significant attention for their potential in treating colitis.Methods: In this study, we extracted NVs from the leaves (LNVs) and stems (SNVs) of Taxus, a well-known natural anti-cancer plant. …”
Get full text

Carbon-Encapsulated Iron Nanoparticles Seeking Integrins in Murine Glioma by Stawarska A, Bamburowicz-Klimkowska M, Bystrzejewski M, Kasprzak A, Grudzinski IP

“…Agnieszka Stawarska,1,* Magdalena Bamburowicz-Klimkowska,1,* Michał Bystrzejewski,2 Artur Kasprzak,3 Ireneusz P Grudzinski1 1Department of Toxicology and Food Science, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland; 2Department of Physical Chemistry, Faculty of Chemistry, Warsaw University, Warsaw, Poland; 3Department of Organic Chemistry, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland*These authors contributed equally to this workCorrespondence: Agnieszka Stawarska, Email agnieszka.stawarska@wum.edu.plPurpose: Targeting integrin receptors for MRI represents a novel method in diagnosing glioblastoma. …”
Get full text

Intratumoral and Peritumoral Radiomics Based on DCE-MRI for Prediction of Microvascular Invasion Grading in Solitary Hepatocellular Carcinoma (≤3 cm) by Li Y, Li H, Feng Y, Lu L, Zhang J, Jia N

“…Yinqiao Li,* Helin Li,* Yayuan Feng, Lun Lu, Juan Zhang, Ningyang Jia Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, 200438, People’s Republic of China*These authors contributed equally to this workCorrespondence: Juan Zhang; Ningyang Jia, Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, 200438, People’s Republic of China, Email zhangjuan0801@126.com; ningyangjia@163.comPurpose: To explore the application value of clinical indicators, radiological features, and magnetic resonance imaging (MRI) radiomics to predict the grading of MVI in nodular hepatocellular carcinoma (≤ 3cm).Methods: A total of 131 patients with hepatocellular carcinoma (HCC) and confirmed microvascular invasion (MVI) who underwent surgical resection between January 2016 and December 2022 were retrospectively analyzed. …”
Get full text

HGH1 Promotes Breast Cancer Progression Through the PI3K/AKT/NF-κB Signaling Pathway: Potential Role for Prognosis and Targeted Therapy by Hu W, Si D, Liu C, Tie D, Xu D, Li N

“…Wenyu Hu,1,* Dikun Si,1,* Chenxi Liu,2,* Danchen Tie,1 Dongdong Xu,1 Nanlin Li1 1Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Air Force Medical University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nanlin Li, Email nanlin-74@163.comIntroduction: Previous studies have shown that the HGH1 gene is associated with poor prognosis in a variety of cancers, but its specific function and molecular mechanism in the pathological process of breast cancer remain unclear.Methods: The relationship between expression of HGH1 and overall survival in BC patients was analyzed. …”
Get full text

Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review. by Victor Sabino de Queiros, Nicholas Rolnick, Phelipe Wilde de Alcântara Varela, Breno Guilherme de Araújo Tinôco Cabral, Paulo Moreira Silva Dantas

“…<h4>Objectives</h4>To provide a comprehensive overview of short-term, high-frequency blood flow restriction training, including main adaptations, myocellular stress, limitations in the literature, and future perspectives.<h4>Methods</h4>A systematic search of electronic databases (Scopus, PubMed®, and Web of Science) was performed from the earliest record to April 23, 2022. …”
Get full text

Comparison between Bolus Intracoronary versus Bolus Intravenous Injection Regimens of Eptifibatide during Primary Percutaneous Coronary Intervention in Patients with Anterior ST-Se... by Mohamed Hassan Nab, Shaimaa Mostafa, Khaled Elrabat, Hamza Kabil, Neama Elmelegy

“…The current study aimed to examine the safety and efficacy of I/C vs I/V bolus regimen dose of eptifibatide during primary percutaneous coronary intervention (PPCI).Material and methods. Prospective, controlled, randomized study enrolled 100 patients with acute anterior ST-segment elevation myocardial infarction (STEMI) eligible for PPCI equally divided into 2 groups (group A received bolus I/C eptifibatide and group B received it I/V) followed by 12-hour continuous I/V infusion. …”
Get full text

Quality of life of gastric cancer patients after radical surgery depending on the status of the duodenal passage by O. M. Asipovich, I. B. Uvarov, V. A. Porkhanov

“…To assess the impact of preservation of the duodenal passage on the quality of life (QOL) after total gastrectomy (TGE) in patients with gastric cancer (GC). Patients and methods. The study included 55 patients with GC who underwent TGE: group I (n = 29) included patients with preservation of the duodenal passage (PDP) using the double tract reconstruction method; Group II (n = 26) included those with standard Roux-en-Y reconstruction. …”
Get full text

Cluster Set Resistance Training Reduces Autonomic Perturbations Compared to Traditional Protocols in Trained Healthy Young Individuals: A Clinical Study by Bianca de Souza Soares, Maria Clara Gomes Alves, Carlos Eduardo Cantelmo, Bruna Cristina de Oliveira Barros, Gustavo Vieira de Oliveira

“…Sixteen participants (seven female, 25 ± 2 years old) performed both cluster set and traditional RT protocols with equal relative intensity (85% 10RM), volume load (4 × 10 repetitions), and rest intervals (120 s). …”
Get full text

Study on the Mechanism of Artesunate in Modulating AR Epithelial Injury and Th2-Type Inflammatory Status by Bao Y, Zhang Z, Shi B, Chen Q, Zhang Y, Zhu X

“…Youwei Bao,&ast; Zhiqiang Zhang,&ast; Binbin Shi, Qi Chen, Ying Zhang, Xinhua Zhu Department of Otorhinolaryngology Head and Neck Surgery, The second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xinhua Zhu, Department of Otorhinolaryngology Head and Neck Surgery, The second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China, Email entzxh@126.comObjective: To evaluate the therapeutic efficacy of Artesunate (ART) in a mouse model of allergic rhinitis (AR) induced by house dust mite (HDM) and explore its underlying mechanism.Experimental Methods: Transcriptome sequencing (RNA-seq) analysis identified differentially expressed genes (DEGs) in nasal mucosa between healthy and allergic mice, with Gene Set Enrichment Analysis (GSEA) revealing STING pathway activation. …”
Get full text

Transparent memory tests with even repeating addresses for storage devices by V. N. Yarmolik, I. M. Mrozek, V. A. Levantsevich, D. V. Demenkovets

“…Mathematical models describing the faulty states of storage devices and the methods used for their detection are investigated. …”
Get full text

Association Between Hysterectomy and Accelerated Aging: Protective Effect of Dietary Fiber and Mediating Role of Creatinine by Qian W, Xu B, Fang Y, Wu X

“…Wen Qian,1,&amp;ast; Binkai Xu,2,&amp;ast; Yuan Fang,1 Xian Wu1 1Department of Operation, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center of Nanjing Medical University, Changzhou, Jiangsu Province, People’s Republic of China; 2Department of Surgery, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center of Nanjing Medical University, Changzhou, Jiangsu Province, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Xian Wu, Email wxcz0519@163.comObjective: To investigate the association between hysterectomy and accelerated aging, with a focus on the mediating effect of renal function and protective role of dietary fiber intake.Methods: The cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2010. …”
Get full text

IL-6 and CD4+/CD8+ are Important Indicators for Predicting Prognosis in Elderly AECOPD Patients: A Retrospective Study by Liu Q, Wang Y, Cao X, Zhang S, Xie J

“…Qingqing Liu,1,2,&ast; Yanhui Wang,1,2,&ast; Xueshuai Cao,1,2 Shan Zhang,1,2 Juan Xie1,2 1Department of General Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, People’s Republic of China; 2Center of Community-Based Health Research, Fudan University, Shanghai, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Juan Xie, Email abclux@126.comPurpose: Evaluating the role of IL-6 and CD4+/CD8+ in predicting the prognosis of elderly patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Patients and Methods: This study retrospectively enrolled 413 elderly patients who were hospitalized for AECOPD between January 2019 and December 2021. …”
Get full text

A Nomogram for Predicting Survival in Patients with SARS-CoV-2 Omicron Variant Pneumonia Based on Admission Data by Yang Y, Li D, Nie J, Wang J, Huang H, Hang X

“…This study aimed to develop a nomogram for predicting survival using chest computed tomography (CT) imaging features and laboratory test results based on admission data.Patients and Methods: A total of 436 patients with SARS-CoV-2 pneumonia (323 and 113 in the training and validation groups, respectively) were enrolled. …”
Get full text

Effects of Curcumin on Iron Overload in Rats by Gülüzar Özbolat, Arash Alizadeh Yegani

“…This study investigated the effects of curcumin on iron overload in rats. Methods: Forty male Wistar rats weighing 139.78 ± 11.95 gm (Mean ± SD) were divided into three equal groups: (i) controls; (ii) iron overload group that received six doses of iron dextran 1000 mg/kg–1 by intraperitoneal injections (i.p.); and (iii) iron overload curcumin group that received six doses of curcumin (1000 mg/kg BW by i.p.).  …”
Get full text

Value of Shear Wave Elastography in the Evaluation of Chronic Kidney Disease by Lakshmana SK, Koteshwar P, Kamath T

“…We obtained a YM measurement cut-off value of 4.43 kPa, a value less than or equal to this suggested a no diseased kidney. This yielded sensitivity and specificity of 92.6% and 80.6%, respectively, with an AUROC of 0.92.Conclusion: Our results demonstrated that shear wave elastography may provide a low-cost, non-invasive method for the morphological assessment and progression of the disease status in chronic kidney disease patients with CKD.Keywords: chronic kidney disease, shear wave elastography, renal parenchymal stiffness…”
Get full text