A Ferritin-Based Eg95 Nanoparticle Vaccine Adjuvanted with pCpG Eliciting Robust Immune Responses Against Cystic Echinococcosis in Mice Model by Gao X, Zhu X, Liu X, Zhou C, Shang Y, Wu T, Jia H, Zhang Z, Li Y, Xin T

“…The commercial Quil-A-adjuvanted Eg95 vaccine was empirically effective for CE control; however, it is expensive and has side effects and insufficient immunity.Purpose: This study aimed to employ a novel adjuvant consisting of a delivery system and an immune potentiator and assess its adjuvanticity to Eg95 antigen, thereby developing a safe and cost-effective novel vaccine against the disease.Methods: A ferritin-based Eg95 nanoparticle antigen was prepared and then mixed with a plasmid containing the TLR9 agonist CpG to formulate a novel nanovaccine. …”
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CURRENT APPROACH TO DEVELOPMENT OF BIOSIMILAR PRODUCTS CONTAINING MONOCLONAL ANTIBODIES AS AN ACTIVE SUBSTANCE – NON-CLINICAL AND CLINICAL STUDIES OF THE FIRST RUSSIAN RITUXIMAB BI... by S. M. Alekseev, K. D. Kaplanov, R. A. Ivanov, E. V. Chernyaeva

“…Within the whole study period  the frequency of AEs, including severe AEs (grade 3-4), associated with the use of monotherapy, were equal in both arms without any significant differences. …”
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Tofacitinib in early active axial spondyloarthritis: protocol of a randomized double-blind, placebo-controlled, multicenter phase IV study, FASTLANE by Valeria Rios Rodriguez, Lidia Sánchez-Riera, Hildrun Haibel, Caroline Höppner, Murat Torgutalp, Fabian Proft, Judith Rademacher, Elke Binder, Annette Diehl, Ivana Vranic, Yuxi Zhao, Rajiv Mundayat, Arne Yndestad, Denis Poddubnyy

“…Recently, the Assessment in SpondyloArthritis International Society (ASAS) defined early axSpA as a diagnosis of axSpA with a duration of axial symptoms equal to or less than 2 years. Tofacitinib is a Janus kinase (JAK) inhibitor for the treatment of ankylosing spondylitis. …”
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Evaluation of Clinical Symptoms of Unilateral S1 Nerve Injury Caused by Disc Herniation the via High Resolution MRI and DTI by Zhang C, Hao W, Guo X, Zhang Y, Fu H, Zhang J

“…ChaoYang Zhang,1,* Wei Hao,1,* Xiaobo Guo,2 Yuna Zhang,1 Hao Fu,1 Jiashan Zhang1 1Department of Radiology, Jincheng General Hospital, Jincheng, Shanxi, People’s Republic of China; 2Department of Orthopaedics, Jincheng General Hospital, Jincheng, Shanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: ChaoYang Zhang, Email Zhangchaoyang8717@163.comBackground: The status of the herniated disc or nucleus pulposus and the extent of injury and clinical symptoms of the compressed S1 nerve fiber bundle were evaluated by high-resolution Magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) techniques.Methods: Forty-two clinically proven patients with unilateral S1 nerve root compression were selected as the case group (n=42), and 20 healthy volunteers were selected as the control group (n=20). …”
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Autologous bone marrow-derived progenitor cell transplantation for myocardial regeneration after acute infarction by Obradović Slobodan, Rusović Sinisa, Balint Bela, Ristić-Anđelkov Anđelka, Romanović Radoslav, Baskot Branislav, Vojvodić Danilo, Gligić Branko

“…This pilot trial reports investigation of safety and feasibility of autologous bone marrow-derived progenitor cell therapy for faster regeneration of the myocardium after infarction. Methods and results. Four male patients (age range 47-68 years) with the first extensive anterior, ST elevation, acute myocardial infarction (AMI), were treated by primary angioplasty. …”
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Does Academic Burnout Alleviate or Exacerbate Internet Dependence in University Students with Depression and Anxiety? by Jiang S, Jia Q, Peng Z, Zhou Q, Yi Q, An Z

“…Moreover, it intends to construct a moderated mediation model to examine how academic burnout moderates the relationship between depressive and anxious emotions and internet addiction and how social support mediates this relationship to determine the psychological motivations underlying addiction.Methods: A questionnaire survey was conducted using the simple random sampling method, which yielded 757 valid responses (response rate: a 93.11% response rate). …”
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Mobile-based peer-led theoretically-designed intervention on continued breastfeeding among Iranian mothers by Afsoon Tizvir, Sakineh Rakhshanderou, Yadollah Mehrabi, Leili Mazar, Samira Daneshvar, Mohtasham Ghaffari

“…Sampling starts with randomly selecting 12 health centers among all health centers in Karaj, Alborz province, and allocating them randomly into two equal groups of intervention and control. A study-specific questionnaire, designed in alignment with TPB, was the primary data collection tool. …”
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Effect of minimally invasive posterior veneer Preparation designs on failure load and mode after fatigue (in-vitro study) by Islam Mohamed Mady, Ahmed Safwat El Kady, Moustafa Nabil Aboushelib, Mohamed Hussein A. Hussein

“…The purpose of the study is to compare the failure load and mode after fatigue among three types of veneer preparation designs for restoring premolars. Methods 64 human premolars were equally divided into four groups. …”
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Antiviral Properties of Water Extracts of Mycelium <i>Inonotus rheades</i> (Pers.) P. Karst. (1882) against the Virus of Tick-Borne Encephalitis Virus <i>in vitro</i> by M. A. Khasnatinov, T. G. Gornostai, I. S. Solovarov, M. S. Polyakova, G. A. Danchinova, G. V. Borovskii

“…The concentration of infectious tick-borne encephalitis virus was determined using the method of titration of plaque-forming components (PFU). …”
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The Diagnostic Performance of AFP, AFP-L3, DCP, CA199, and Their Combination for Primary Liver Cancer by Liu Y, Jiang W, Li X, Zhao H, Wang S

“…This study aims to identify novel biomarkers to improve the diagnostic ability of PLC.Patients and Methods: This study included 94 patients with PLC, 128 patients with benign liver disease (BLD), and 79 normal controls (NC) were included. …”
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Effect of Selected Kinesiology Taping Applications on Reducing Pain and Accelerating Rehabilitation in Children with Osgood-Schlatter Disease by Krzysztof Kuchmacz, Kinga Żmijewska, Magdalena Mikos, Natalia Kuchmacz, Natalia Madej-Chmiel, Artur Gądek

“…Subjects were divided into 2 equal groups: the study group (n=30) and the control group (n=30). …”
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Low-intensity blood flow restriction (LI-BFR) and moderate-intensity improves quadriceps strength and thigh circumference in older women by Jonathan Wibisono Tumali, Rwahita Satyawati, Nur Sulastri

“…This study aims to evaluate the effects of moderate-intensity and low-intensity blood flow restriction exercises on quadriceps femoris strength and thigh circumference in healthy elderly women. Materials and methods. The sample size was of 88 subjects equally randomized into a moderate-intensity group and a blood-flow restriction group. …”
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Application of technology to empower women in social entrepreneurship: A review by Saikat Gochhait, Renuka Lenka, Aidin Salamzadeh

“…This is not just a matter of promoting women-led businesses. It applies equally to the practice of sustainable development. …”
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Superiority of Combined Endurance-Resistance Exercise for Increasing the Molecular and Pyramidal Layers Thickness of Hippocampal Tissue in Alzheimer\'s Laboratory Large White Rats by Maryam Keshvari, Ali Heidarianpour, Farzaneh Chehelcheraghi

“…This study was conducted to investigate the effect of swimming endurance, resistance, and combined exercises on the molecular and pyramidal layers of the hippocampus tissue thickness of Alzheimer's rats. Methods: In this experimental study, 40 large white Wistar laboratory rats (6 weeks old; Weight 180-200 g) were randomly and equally divided into five groups: healthy control, Alzheimer's control, endurance, resistance, and combined. …”
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Interscalene block alone vs interscalene block with erector spinae plane block for shoulder arthroscopy anesthesia: a randomized-controlled trial by Hussen Gamal Almawardy, Mohammed Said ElSharkawy, Shimaa Mostafa Elrahwan, Mhmoud Abdalsattar Almohasseb, Islam Morsy

“…Patients were equally randomized to Group IE: received ISB using 10-mL bupivacaine 0.5% plus ESPB at T2 using 10-mL bupivacaine 0.5%. …”
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Correlation Between the Koebner Phenomenon and Clinical Features in Vitiligo by Tang X, Hao C, Fan M, Dong P, Qi Y, Gao J, Huang H, Chen M, Wang W

“…Xianfa Tang,1– 3,&ast; Cuilan Hao,1– 3,&ast; Min Fan,1– 3,&ast; Penghao Dong,1– 3 Yinyin Qi,1– 3 Jinping Gao,1– 3 He Huang,1– 3 Mengyun Chen,1– 3 Wenjun Wang1– 3 1Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China; 2Institute of Dermatology, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 3Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, Anhui, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Wenjun Wang, Email wangwj0720@sina.comPurpose: To investigate the correlation between the presence of the Koebner phenomenon (KP) and clinical features of patients with vitiligo.Patients and Methods: The clinical characteristic data, including age, age of onset, disease duration, gender, clinical stage, clinical type, family history, and comorbid immune-related diseases, of 1472 patients with/without KP were analyzed with SPSS 17.0 software.Results: Of the 1472 patients, 290 (19.70%) were positive for KP. …”
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Experimental research of impact on psychological state for adolescents with high-intensity interval training intervention by Yu-Tong Li, Yang Zhou

“…Participants were equally divided into an experimental group (HIIT intervention) and a control group (moderate-intensity continuous training). …”
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Integrative Proteomics and Phosphoproteomics Profiling of Symptomatic Accessory Navicular Bone Based on Tandem Mass Tag Technology by Liu B, Wei R, Wang Y, Cheng Z, Jiang L, Pu X, Zhang Y, Wang Y, Kang Q

“…This study aims to investigate the proteomics and phosphoproteomics profile of foot injury with the ANB after athletic training.Patients and Methods: We collected ANB tissues and normal bone (NB) tissues from 5 foot injury patients with ANB after 3 months of athletic training to perform proteome sequencing by tandem mass tag (TMT) technology. …”
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Carrier-Free Silibinin/Sorafenib Microparticles Alleviate Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Fatty Acid Metabolism by Han F, Wang H, Wang L, Fan L, Peng S, Hou X, Shu X, Sun B, Liu Y

“…Feifei Han,1,&amp;ast; Haiping Wang,1,2,&amp;ast; Li Wang,1 Limei Fan,1 Sibei Peng,1 Xiaoying Hou,1,2 Xiji Shu,1,2 Binlian Sun,1,2 Yuchen Liu1,2 1Cancer Institute, School of Medicine, Jianghan University, Wuhan, Hubei, 430056, People’s Republic of China; 2Hubei Key Laboratory of Cognitive and Affective Disorders, Jianghan University, Wuhan, Hubei, 430056, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Yuchen Liu, Email yuchen.liu@jhun.edu.cnIntroduction: Metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by excessive fat accumulation in the liver, is the most prevalent cause of chronic liver disease globally. …”
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Effects of the 2018 European summer heatwave on the incidence of sporadic bacterial gastroenteritis in a temperate maritime climate region (Republic of Ireland) by Martin Boudou, Patricia Garvey, Coilín ÓhAiseadha, Jean O'Dwyer, Daniel T. Burke, Paul Hynds

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