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20221
Causal Relationship Between Sex Hormone Binding Globulin and Obstetrical Disorders: A Two-Sample Bidirectional Mendelian Randomization Study
Published 2025-07-01“…This Mendelian randomization (MR) study examined SHBG’s causal effects on 12 obstetrical conditions.Methods: Using cis-protein quantitative trait loci (cis-pQTLs) of SHBG as instrumental variables, we conducted MR analyses in FinnGen and UK Biobank (UKBB), followed by meta-analyses. …”
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20222
Quantitative analysis of tumor-infiltrating lymphocytes in meningiomas of the brain
Published 2016-08-01“…The lowest quantity of CD4+ and CD8+ TIL was established in angiomatous subtypes and the median amount of CD4+ and CD8+ TIL in meningothelial subtypes was the highest, it was equal to 9 (1; 26) and 16 (8; 47) cells respectively. …”
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20223
Interpretable Ordinal-Aware With Contrastive-Enhanced Anomaly Severity Detection on UAV Flight Log Messages
Published 2025-01-01“…Therefore, the proposed method accordingly addresses the task objective with a promising performance while being interpretable and trustworthy.…”
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20224
Gender bias in urology: The role of gender in selecting urology as a medical specialty
Published 2025-01-01“…Addressing these issues is crucial to achieving gender equality within the field.…”
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20225
Conversations Between Family Members and Physicians in Intensive Care Unit During Shared Decision-Making: A Qualitative Observational Study
Published 2025-07-01“…Qing Lu,1,* Juan Ji,2,* Xiao-yan Lu,1 Qiong-Hua Yin,1 Yi-Qun Yang3 1Department of Intensive Care Unit, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Department of Outpatient, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 3Department of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yi-Qun Yang, Department of Nursing, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Gu Su Qu, Suzhou, Jiangsu, 215000, People’s Republic of China, Tel +86051213656245355, Email 592436680@qq.comIntroduction: It is necessary to understand the decision-making dynamics between physicians and families so as to help families better participate in shared decision-making.Methods: A qualitative observational research was conducted. …”
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20226
The Mechanism of Traditional Chinese Medicine and Natural Medicine in Treating Chronic Obstructive Pulmonary Disease
Published 2025-04-01“…Lei Li,1,* Xiao-Feng Liu,1,2,* Zhi-Fang Cui,1 Heng Zou,1 Shu-Ling Liu,1,2 Hong-Wu Wang1 1Respiratory Disease Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 101121, People’s Republic of China; 2Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong-Wu Wang, Respiratory Disease Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 116 Cuiping West Road, Tongzhou District, Beijing, 101121, People’s Republic of China, Email wanghongwu2015@126.com Shu-Ling Liu, Respiratory Disease Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 116 Cuiping West Road, Tongzhou District, Beijing, 101121, People’s Republic of China, Email 553638521@qq.comEthnopharmacological Relevance: Chronic obstructive pulmonary disease (COPD) is one of the crucial chronic diseases that seriously endangers the health of residents in China. …”
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20227
Pharmacoeconomic analysis of using cyclin-dependent kinase 4 and 6 inhibitors in the first line treatment of HR-positive HER2-negative advanced breast cancer
Published 2020-02-01“…We used cost minimization method for the clinical and economic study, since palbociclib and ribociclib are equally or comparably effective, according to earlier literature. …”
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20228
Identifying Google search engine optimization techniques and providing a framework to improve the ranking of websites
Published 2024-12-01“…Using the purposeful sampling method, authoritative articles and websites, Delphi panel members, and experts in the field of SEO were identified. …”
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20229
Assessment of Personalized Exercise Prescriptions Issued by ChatGPT 4.0 and Intelligent Health Promotion Systems for Patients with Hypertension Comorbidities Based on the Transtheo...
Published 2024-11-01“…Yang Xu,* Qiankun Liu,* Jiaxue Pang, Chunlu Zeng, Xiaoqing Ma, Pengyao Li, Li Ma, Juju Huang, Hui Xie College of Nursing, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hui Xie, Bengbu Medical University, Donghai Avenue, Longzihu District, Bengbu City, Anhui Province, People’s Republic of China, Email hui2122@sina.comPurpose: Exercise is a vital adjunct therapy for patients with hypertension comorbidities. …”
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20230
Relaxation and physicomechanical characteristics of polyethylenes with different molecular weights
Published 2019-12-01“…We have shown that under isothermal conditions, when the stress equals the yield strength, the removal of the external action results in a two-stage response. …”
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20231
Comparison of cefixime and amoxicillin plus metronidazole in the treatment of chronic periodontitis
Published 2016-01-01“…The aim of this study was to examine patients with chronic periodontitis in order to evaluate the efficacy of non-surgical therapy and combination of amoxicillin and metronidazole compared with cefixime, which has not been so far used for the treatment of this disease. Methods. Adult patients with chronic periodontitis (n = 90) underwent non-surgical periodontal treatment (zero-day) and then randomly divided into three groups. …”
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20232
Effect of Biodegradable and Polypropylene Film Packaging on the Safety Profile of Jelly Marmalade
Published 2020-10-01“…However, the barrier properties of biodegradable films still remain understudied. Study objects and methods. The research featured the safety profile of gelatinous confectionery products during storage in biodegradable and polypropylene films. …”
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20233
Efficacy and Safety of HER2-Targeted Agents for Breast Cancer with HER2-Overexpression: A Network Meta-Analysis.
Published 2015-01-01“…<h4>Impact</h4>This study suggests that both T-DM1 and PEHC therapy are potentially and equally useful treatments for HER2+ breast cancer.…”
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20234
Late results of surgical treatment of critical ischemia of the lower extremities after one-staged direct revascularization
Published 2021-07-01“…Occlusion of anterior tibial artery was revealed most frequently – in 72% of the patients, than in fibular - in 42% of patients (p=0.00), and equally frequently with occlusion of posterior tibial artery – in 68% (p=0.61). …”
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20235
Possible relationship between pre-pregnancy maternal body mass index and offspring hippocampus: An experimental study in albino Wistar rat
Published 2024-11-01“…On postnatal day1, pups were randomly adjusted to 8/dam with equal gender ratio. On 15 day postpartum, all pups were sacrificed. …”
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20236
One-Year Risk Prediction of Elevated Serum Uric Acid Levels in Older Adults: A Longitudinal Cohort Study
Published 2024-11-01“…Dexian Zhang,1,2,* Xinxin Xu,2,3,* Zhibin Ye,1,2 Zhenxing Zhang,1,2 Jing Xiao1,2 1Department of Nephrology, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 3Clinical Research Center for Geriatric Medicine, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhenxing Zhang; Jing Xiao, Department of Nephrology, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China, Email contraindication@163.com; jingxiao13@fudan.edu.cnObjective: To develop and externally validate a nomogram to predict elevated serum uric acid (SUA) levels in older adults.Study Design: This is a longitudinal Chinese cohort study.Methods: A cohort of 2788 older adults was established at Huadong Hospital, followed-up for at least one year, and screened for risk factors for elevated SUA levels. …”
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20237
The Miasma Mentality: Investigating the Association Between Beliefs in Noxious Fumes and Obstructive Pulmonary Disease (COPD), Symptoms, and Quality of Life
Published 2025-02-01“…While established risk factors like smoking and occupational exposures are well-documented, patients’ beliefs—especially those from the miasma theory attributing disease to “bad air” in cultures like China—may also significantly influence health outcomes.Methods: This case-control study was conducted at Hospital of Hebei University of Traditional Chinese, involving 500 individuals diagnosed with COPD and 500 matched control participants. …”
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20238
Сost-effectiveness of the second wave of protease inhibitors in the treatment of chronic hepatitis C (genotype 1) in patients not previously treated with antiviral drugs, and for r...
Published 2016-04-01“…The protease inhibitors (PI) actively using for the treatment of chronic hepatitis C (CHC).The aim of this analysis was to evaluate the cost-effectiveness of narlaprevir and simeprevir in the CHC (genotype 1) therapy in treatment-naïve patients and relapses.Material and methods. Analysis of the cost-effectiveness of simeprevir and narlaprevir was conducted from the perspective of the health care system and base on QUEST-1, QUEST-2, ASPIRE and PIONEER clinical trials. …”
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20239
Prevalence of Hyperuricemia and Rheumatoid Factor Positivity Among Patients Aged 35 and Above in Huye District, Southern Province of Rwanda
Published 2024-11-01“…This study aimed to determine the prevalence of hyperuricemia and RF positivity in patients aged 35 and above in Huye district of Rwanda.Patients and Methods: We conducted a cross-sectional study from October 2023 to January 2024, enrolling 367 patients from Huye and Matyazo Health Centers. …”
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20240
Evaluation of Very-High-Frequency Ultrasound Imaging Characteristics of Dermatofibroma
Published 2024-12-01“…Herein, we analyze the sonographic features and application value of VHF ultrasound in the diagnosis of DF.Methods: Clinical data from 153 patients with pathologically confirmed DF from January 2019 to December 2023 were retrospectively analyzed using high-resolution VHF ultrasound, including size, location, shape, edge, boundary, interior echo, blood supply and so on.Results: The VHF sonographic features of DF showed that the maximum diameter of the lesions was about 7.29 ± 2.85 mm (mean ± standard deviation). …”
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