Construction and Characterization of an lpxM-Deficient Acinetobacter baumannii Strain Using a pyrF/5-FOA Counterselection System by Gao C, Jiang K, Qi J, Zheng C, Liang Y

“…This study aims to investigate the effects of the lpxM gene on the growth and drug susceptibility of MDR-AB.Methods: The standard strain of Acinetobacter baumannii (A. baumannii, AB) AYE was selected as the target. …”
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Investigating ethical tradeoffs in crisis standards of care through simulation of ventilator allocation protocols. by Jonathan Herington, Jessica Shand, Jeanne Holden-Wiltse, Anthony Corbett, Richard Dees, Chin-Lin Ching, Margie Shaw, Xueya Cai, Martin Zand

“…Moreover, concerns about racial discrimination in triage protocols require thinking carefully about the tradeoff between enforcing equality of survival rates and maximizing the lives saved in each sub-population.…”
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Complex Evaluation Oxygen Status and Lipid Metabolism Indexes in Newborns with Perinatal Hypoxia and Hypovolemic Shock by Svetlana A. Perepelitsa

“…To asses of metabolism, lipid metabolism and oxygen status parameters in newborns with perinatal hypoxia.Materials and Methods. 53 newborn babies born with signs of severe hypoxia and low Apgar scoring equal to 2 at the 1st minute of life were enrolled in the study. …”
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Advancing Therapeutic Strategies with Polymeric Drug Conjugates for Nucleic Acid Delivery and Treatment by Ullah A, Khan M, Zhang Y, Shafiq M, Ullah M, Abbas A, Xianxiang X, Chen G, Diao Y

“…The review delves into the conjugation strategies, preparation methods, and various classes of PDCs, as well as strategic design, highlighting their role in nucleic acid delivery. …”
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Community-based type 2 diabetes screening programmes designed for priority populations: a scoping review protocol by Ghazal S Fazli, Muhanad Ahmed Ali, David Gerstle, Fatema Mahad Ali, Aimen Zehra

“…The purpose of this scoping review is to better understand the design and implementation of screening and early detection of type 2 diabetes in community settings for priority populations to reduce missed or delayed diagnoses and future potential adverse outcomes.Methods This scoping review will adopt the methodological framework of Arksey and O’Malley and be enhanced using Levac et al recommendations. …”
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Circumferentially Aligned Electrospun Vascular Grafts Improves Its Vascular Regeneration and Remodeling in vivo by Xiong M, Yang L, Liu X, Luo S, Wang Y

“…Man Xiong,1,* Lei Yang,2,* Xinfang Liu,2 Sidong Luo,2,3 Yeyang Wang2– 4 1School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2Orthopaedic Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, People’s Republic of China; 3The Second School of Clinical Medicine, Southern Medical University, Guangzhou, People’s Republic of China; 4Orthopaedic Center, Zhaoqing Central People’s Hospital, Zhaoqing, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yeyang Wang, Email yeyangwyy@163.comIntroduction: Despite the rapid development of small diameter vascular graft (SDVG), the ability of synthetic grafts to facilitate tissue remodeling and regeneration remains an important challenge within regenerative medicine.Methods: Based on our previous research work, silk fibroin (SF)/fibrin vascular grafts were successfully fabricated using electrospinning technology, and it was demonstrated that the grafts had superior mechanical strength, good cytocompatibility and histocompatibility. …”
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Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Changes in Primary Angiitis of the Central Nervous System by Lu P, Cui L, Zhang L, Wang H, Yin L, Tian D, Zhang X

“…This study aimed to explore changes in the plasma metabolome during the active and remission phases of PACNS and identify potential biomarkers.Methods: We collected plasma samples from 35 patients with PACNS during the active and remission phases and 22 samples from patients with non-inflammatory disease as controls. …”
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Evaluation of the Abbott BinaxNOW rapid antigen test for SARS-CoV-2 infection in children: Implications for screening in a school setting. by Neeraj Sood, Rashmi Shetgiri, Anna Rodriguez, Dianna Jimenez, Sonia Treminino, Amanda Daflos, Paul Simon

“…Positive concordance was negatively associated with Ct values and was 93.8% (95% CI: 69.8% to 99.8%) for children with Ct values less than or equal to 25. 548 children tested negative on RT-PCR; 539 or 98.4% (95% CI: 96.9% to 99.2%) of these also tested negative on the rapid antigen test. …”
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East Ural Radioactive Trace: cancer mortality over a 57-year period (1957-2014) by S. S. Silkin, L. Yu. Krestinina, A. V. Akleyev

“…The analysis of the cancer mortality risk was carried out with the EPICURE statistical package using the Poisson regression method. Confidence intervals were calculated using the maximum likelihood method. …”
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Prescribing Trends of Fixed-Dose Combination Antibiotics Not Recommended by the WHO (FNRs) for ICU Patients in Six Major Areas of China During a Seven-Year Period by Zhou L, Zhao Y, Zhu J, Liu J, Liang G, Yang Y, Han G, Yu Z

“…Liujun Zhou,1,* Yuhua Zhao,1,2,* Jianping Zhu,1 Jieqiong Liu,1 Gang Liang,1 Yi Yang,1 Gang Han,1 Zhenwei Yu1 1Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2Department of Pharmacy, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gang Han; Zhenwei Yu, Email 3199022@zju.edu.cn; yzw_srrsh@zju.edu.cnObjective: To evaluate the prescribing trends of fixed-dose combination antibiotics not recommended by the WHO (FNRs) for intensive care unit (ICU) patients in six major areas of China from 2013 to 2019.Methods: A descriptive analysis was conducted using the pharmacy prescription data. …”
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Mechanisms and Nanomedicine Interventions of Acute Lung Injury Induced by Intestinal Ischemia-Reperfusion: A Mini Review by Li G, Jin B, Zhou J, Sun T, Wang S, Fan Z

“…Current treatments include anti-inflammatory, antioxidant and anti-apoptotic drugs, as well as surgical interventions and traditional Chinese medicine. However, these methods have high drug toxicity and limited efficacy. …”
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Associations Between Physical Activity and Preserved Ratio Impaired Spirometry: A Cross-Sectional NHANES Study by Fu X, Guo J, Gu X, Chen L, Ju J, Huang H

“…We aimed to evaluate the relationship between physical activity and the risk of PRISm.Methods: A cross-sectional study was conducted using data from US adults who participated in the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2012. …”
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Ultraviolet B (UVB) Radiation Induces Skin Alterations, Emperipolesis and Decreases the Erythroid-to-myeloid Ratio in Rats by Verda Farida, Dion Adiriesta Dewananda, Muhammad Novrizal Abdi Sahid, Siti Isrina Oktavia Salasia

“…Therefore, this study was conducted to investigate the alteration of the skins, emperipolesis, and the change in erythroid and myeloid cell population in bone marrow after UVB irradiation. METHODS: Ten Wistar rats were divided equally into control and UVB-irradiated group. …”
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Experience of one single surgeon with the first 500 robot-assisted laparoscopic prostatectomy cases in mainland China by Huan Chen, Bijun Lian, Zhenyang Dong, Yan Wang, Min Qu, Feng Zhu, Yinghao Sun, Xu Gao

“…Objectives: To summarize the experience of the first 500 robot-assisted laparoscopic radical prostatectomy (RALP) cases by one surgeon and analyze the influencing factors of functional and oncological outcomes. Methods: Between April 2012 and October 2017, 500 patients who underwent RALP were included and divided sequentially into five equal groups. …”
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Analysis of Cost and Treatment Effects in the Care Given for Graves' Disease: A Swedish Cost–Utility Analysis by Lars Lindholm, Gabriel Sjölin, Annika Jonsson, Mirna Abraham‐Nordling, Göran Wallin, TT‐12 Study Group, Helena Filipsson Nyström

“…The incremental cost‐effectiveness ratio was equal to 40,488 Euro per QALY gained. In recurrent GD, the QALY weight for surgery after ATD was 0.76 compared with 0.79 when surgery was the initial treatment. …”
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Do fully erupted third molars affect the dental and periodontal health of adjacent second molars? A CBCT-based retrospective study in the Yemeni population by Manal M. Al-Hajri, Abduljabbar M. Al-Sameai

“…Scans were divided equally into Group I (with fully erupted M3s, n = 200) and Group II (without M3s, n = 200). …”
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Effects of Superimposed Blood Flow Restriction on Isokinetic Knee Extension by Darío Rodrigo-Mallorca, Joaquín Mollá-Sanchis, Iván Chulvi-Medrano, Luis M. Franco-Grau

“…<b>Objective:</b> To evaluate changes in the isokinetic concentric moment of the knee extensors and the moment–velocity curve during the application of no BFR compared to superimposed BFR. <b>Methods:</b> A total of 37 physically active adults [33.73 (10.96) years; 11 females] performed three sets of isokinetic concentric knee extensions, each including three angular velocities (300°/s, 210°/s, and 120°/s; BIODEX dynamometer). …”
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Comparison Between End-to-end Anastomosis and Buccal Mucosa Graft in Short Segment Bulbar Urethral Stricture: a Meta-analysis Study by Prahara Yuri, Irfan Wahyudi, Arry Rodjani

“…Aim: to compare long term follow-up between end-to-end urethroplasty and bucal mucosal graft for the management of patients with short bulbar urethral stricture. Methods:we conducted a meta-analysis of cohort studies. …”
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The Association of Matrix Metalloproteinase‐1, ‐2, ‐3, ‐7, and ‐13 Gene Polymorphisms With Peri‐Implantitis in an Iranian Population: A Case–Control Study by Leila Saremi, Soheil Shahbazi, Mohammad Ebrahim Ghaffari, Saharnaz Esmaeili, Shirin Lotfipanah, Reza Amid, Mahdi Kadkhodazadeh

“…According to current knowledge, the aforementioned complication is not equally distributed across different populations, and gene polymorphisms might be one contributing factor. …”
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Socioeconomic position and urban environments as drivers of antimicrobial resistance? An ecological study in Germany, 2010 to 2019 by Niels Michalski

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