Comparison of clinical efficacy between external anal sphincter bareness and the Hanley procedure for high horseshoe anal fistula by Zhang Jun, Chen Bo, Zheng Kaizhong, Zheng Xia, Liu Yicheng, Mao Chang, Zheng De, Xu Jin, Wang Qingming

“…[Conclusion] The external anal sphincter bareness proves to be an effective surgical method for the treatment of high horseshoe anal fistula. …”
Get full text

Detection of moderate to high antiphospholipid antibodies by chemiluminescence meets 2023 APS classification criteria by Haiyue Jiang, Yaqing Yang, Zihan Tang, Haoyu Pan, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Qiongyi Hu, Jianfen Meng, Huihui Chi, Zhuochao Zhou, Jinchao Jia, Hui Shi, Chengde Yang, Jialin Teng, Tingting Liu

“…However, enzyme-linked immunosorbent assay (ELISA) remains the sole specified method for antiphospholipid antibody detection. This study aims to establish moderate and high levels of anticardiolipin(aCL) and anti-β2-glycoprotein I antibodies (anti-β2GPI) using chemiluminescence assay (CIA) and to investigate the diagnostic efficiency and risk stratification capabilities of CIA in comparison to ELISA. …”
Get full text

Land instability Compounds the risk of sea level rise in Alexandria, Egypt by Rejoice Thomas, Sara Zouriq, Shahryar Fazli, Amr Fawzy, Nikolay Grisel Todorov, Surendra Maharjan, Wenzhao Li, Erik Linstead, Daniele Struppa, Hesham El-Askary

“…Moreover, in the absence of a recent, openly accessible Digital Elevation Model (DEM) with satisfactory resolution, we developed a novel approach to update DEM using the Small Baseline Subset method. This approach enabled us to generate a projected DEM for the year 2040, facilitating the creation of a stream network based on this “future DEM”. …”
Get full text

Quality of life assessment in patients treated due to chronic pancreatitis by Dragović Saša, Vulović Maja, Stamenković Dušica, Rančić Nemanja, Mitrović Miroslav, Bezmarević Mihailo, Jovanović Milan, Pantić Ivan, Rujanovski Zoran, Lepić Sanja, Milev Boško

“…According to the method of treatment, patients completed the questionnaire. …”
Get full text

High‐Throughput Proteoform Imaging for Revealing Spatial‐Resolved Changes in Brain Tissues Associated with Alzheimer's Disease by Yue Sun, Dan Liu, Yu Liang, Xue Yang, Xinxin Liu, Baofeng Zhao, Zhen Liang, Yukui Zhang, Lihua Zhang

“…However, challenges remain regarding throughput and coverage. A robust method is developed for high‐throughput proteoform imaging (HTPi) by combining matrix‐assisted laser desorption ionization mass spectrometry imaging (MALDI MSI) and region‐specific top‐down proteomic analysis. …”
Get full text

An interpretable machine learning model based on computed tomography radiomics for predicting programmed death ligand 1 expression status in gastric cancer by Lihuan Dai, Jinxue Yin, Xin Xin, Chun Yao, Yongfang Tang, Xiaohong Xia, Yuanlin Chen, Shuying Lai, Guoliang Lu, Jie Huang, Purong Zhang, Jiansheng Li, Xiangguang Chen, Xi Zhong

“…The SHAP waterfall plots were used to visualize the decision-making process for a single individual. …”
Get full text

Population pharmacokinetics of high-dose methotrexate in patients with primary central nervous system lymphoma by Shifeng Wei, Shifeng Wei, Sitian Zhang, Dan Wang, Dan Wang, Dongjie Zhang, Qian Lu, Jiayi Mo, Jiayi Mo, Zhilin Yang, Zhilin Yang, Leyi Guan, Yingjun He, Zhigang Zhao, Zhigang Zhao, Shenghui Mei, Shenghui Mei

“…This study aims to employ population pharmacokinetic (PPK) models to investigate the pharmacokinetics of MTX in Chinese patients with PCNSL, thereby facilitating personalized therapeutic strategies for these patients.MethodA retrospective dataset comprising 6074 MTX plasma concentrations from 752 adult patients with PCNSL receiving high-dose methotrexate (HD-MTX) therapy was employed to construct the PPK model, utilizing the nonlinear mixed-effects modeling approach. …”
Get full text

Pt@ZnCo₂O₄ Microspheres as Peroxidase Mimics: Enhanced Catalytic Activity and Application for L-Cysteine Detection by Shuqi Liao, Weisen Deng, Feng Yang, Jutao Zhou, Ling Wu, Donghong Yu, Zhong Cao

“…Herein, we employed ZnCo₂O₄ microspheres as carriers to synthesize Pt-doped composites with different amounts using a one-pot method. The morphology and structure of the synthesized materials were characterized using XRD, SEM, BET, FT-IR, XPS, and Zeta potential techniques. …”
Get full text

Modified Laparoscopic Inverted Triangle Model for Extended Lesion Resection in the Treatment of Symptomatic Localized Adenomyosis in Women Who Have Completed Childbirth by Libing Liu, Weiwei Wei, Huimin Tang, Yao Chen, Hong Zheng, Bin Tang, Ruxia Shi, Jiming Chen, Bairong Xia, Bingying Lu

“…Conclusions: Modified laparoscopic inverted triangle model for extended lesion resection is a safe and effective conservative surgical method for treating dysmenorrhea focal adenomyosis.…”
Get full text

In-vivo sclera thickness measurements in experimental myopia of guinea pigs by Ruiheng Zhang, Chuyao Yu, Li Dong, Yitong Li, Xuhan Shi, Haotian Wu, Wenda Zhou, Heyan Li, Wenbin Wei

“…Abstract The sclera is the target organ of axial elongation during myopia onset and progression. Visualizing the sclera in-vivo is important for monitoring the dynamic changes of the sclera remodeling in experimental myopia. …”
Get full text

Evolving Cultural Experience of Historical Places: From Livability to Visibility (A Case Study of Naqsh-e Jahan Square in Isfahan) by Seyed Mahdi Etemadifard, Amirmohammad Niroumand

“…Materials and MethodsGiven the nature of the research topic and the requirements of the field, this study employed an ethnographic approach. …”
Get full text

Reactivating the phototransduction cascade with a mutation agnostic gene therapy preserves vision in rod-cone dystrophies by Cardillia-Joe Simon, Hanen Khabou, Antoine Chaffiol, Marco Rucli, Marion Finzi, Nat Norberg, Anaïs Grimaud, Brix Mücher, Mélissa Desrosiers, Serge Sancho, Vera Lucia Bonilha, Kate Grieve, Jens Duebel, Michel Paques, Serge Picaud, José Alain Sahel, Isabelle Audo, Stefan Herlitze, Deniz Dalkara

“…This GIRK-channel-based strategy offers a promising method to preserve high-quality vision in RCD patients, regardless of their specific genetic mutation.…”
Get full text

Identification of Agricultural Events, Businesses and Landscapes in Chaharmahal and Bakhtiari Province by Golrokh Amiri Dowrhooni, Neda Torabi Farsani, Majid Farhadi Uonaki, Mehdi Karami Dehkordi

“…In order to achieve the goals, the qualitative method (thematic analysis) was used. The results of the analysis of the interviews illustrated that the province includes tangible and intangible agricultural heritage and diverse agricultural landscapes for the development of agritourism. …”
Get full text

Dataset and multivariate statistical tools for mathematical modeling of water desorption isotherms and infrared spectral properties of cupuassu (Theobroma grandiflorum L.) pulpMend... by Andrés F. Bahamón-Monje, Paola A. García-Rincón, Gentil A. Collazos-Escobar, Claudia M. Amorocho-Cruz, Nelson Gutiérrez-Guzmán

“…The dataset includes experimentally determined desorption isotherms within a water activity range of 0.1–1 at 25 °C, obtained using the Dynamic Dewpoint Isotherm (DDI) method. Infrared spectra were acquired via Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy, covering the wavenumber range of 4000–650 cm–1 with a resolution of 8 cm–1. …”
Get full text

Modified transforaminal epidural steroid injection combined with pulsed radiofrequency: an effective treatment measure for lumbar radiculopathy by Qi Yan, Xianggu Zhong, Jiarong Li, Leyu Zhao, Junjie Niu, Dawei Song, Jinning Wang, Yun Teng, Tianyi Wu, Xiao Sun, Rui Chen, Shuangfei Wang, Jun Zou

“…Our findings indicated that this method can efficiently and swiftly relieve patients’ radicular discomfort and produce enduring therapeutic effects.…”
Get full text

Prevalence and determinants of periodontitis among a population with knee osteoarthritis, a cross-sectional study at the Douala General Hospital (Littoral, Cameroon) by Herna Stella Chimy Tchounchui, Fernando Kemta Lekpa, Sylvain Raoul Simeni Njonnou, Clarisse Mapa-Tassou, Christian Deube Ngako, Faustin Atemkeng Tsatedem, Félicité Soh Maleu Mbah, Lawrence Essama Eno Belinga, Francine Same Bebey, Jérôme Ateudjieu, Simeon Pierre Choukem

“…We included 253 participants (201 women) with a median age of 63 years [54–70]. The mean visual analog scale was 52.7 ± 27.9 mm. The mean Lequesne index was 12.25 ± 5.03. …”
Get full text

Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? by Benoit Mesnard, MD, Christophe Masset, MD, PhD, Etohan Ogbemudia, MD, PhD, Sarah Bruneau, PhD, Mohamed Elzawahry, MD, Stéphanie Le Bas-Bernardet, PhD, David Minault, Jeremy Hervouet, Diego Cantarovich, MD, PhD, Jérôme Rigaud, MD, PhD, Lionel Badet, MD, PhD, Peter Friend, MD, PhD, Rutger Ploeg, MD, PhD, Gilles Blancho, MD, PhD, James Hunter, MD, PhD, Thomas Prudhomme, MD, Julien Branchereau, MD, PhD

“…Static cold storage (SCS) remains the standard method for organ preservation. The development of parenchymal edema during prolonged hypothermic machine perfusion (HMP) was a major barrier to the introduction of this technique for the preservation of pancreases. …”
Get full text

Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults by Michael G. Nanna, Daniel Wojdyla, Eric D. Peterson, Ann Marie Navar, Jeff D. Williamson, Lisandro D. Colantonio, Stephen Y. Wang, Yasser Jamil, Alain G. Bertoni, Musarrat Nahid, Abdulla A. Damluji, Parag Goyal, Sarwat I. Chaudhry, Thomas M. Gill, Karen P. Alexander

“…Variable selection, including functional status, was based on the least absolute shrinkage and selection operator method. The cognitive impairment (N=3466) and ASCVD (N=4403) model populations were split into derivation and validation cohorts with external validation, then performed in MESA (Multi‐Ethnic Study of Atherosclerosis). …”
Get full text

Optimized Type-2 Fuzzy Logic Control for Low-Speed Vehicle Pedal Pressing Automation Using Hybrid Spiral Sine Cosine Algorithm by Azrul Azim Abdullah Hashim, Nor Maniha Abdul Ghani, Salmiah Ahmad, Mohd Ruzaini Hashim, Noor Zirwatul Ahlam Naharuddin, Addie Irawan

“…Physical modeling and simulation were done in Simscape MATLAB, which provides an opportunity for modeling and visual description of the actuator system's relationship with the dynamics of the car. …”
Get full text

Modified costotransverse approach combined with autologous iliac bone graft fusion and internal fixation in thoracic tuberculosis by Mengcheng Wei, Shishuang Zhang, Qingbo Li, Lei Cai, Junlong Zhou, Weijun Liu

“…Currently, it is believed that the posterior approach alone is superior to both the anterior and the combined anterior-posterior surgical methods in correcting spinal kyphosis and maintaining spinal stability. …”
Get full text