Prediction of Ki-67 Expression in HIV-Associated Lung Adenocarcinoma Patients Using Multiple Machine Learning Models Based on CT Imaging Radiomics by Song C, Chen J, Zhao C, Song S, Yang T, Huang A, Liu R, Pan Y, Xu C, Chen C, Zhu Q

“…Therefore, developing a non-invasive and accurate method for Ki-67 prediction holds significant clinical importance. …”
Get full text

The Median Effective Dose of Ciprofol Combined with Sufentanil for Inhibiting Responses to Gastroscope Insertion in Obese Patients: A Prospective, Single-Center Study by Xue Z, Liu X, Qian W, Yang N, Pan Y, Zhou Y, Jiang W, Li F, Qian B

“…All patients received 0.1 μg/kg of sufentanil, and the ciprofol dose was determined by the modified Dixon sequential method with an initial dose of 0.4 mg/kg and a dose gradient of 0.01 mg/kg. …”
Get full text

FACTORS OD DENTURES’ MALADJUSTMENT, ITS PREVENTION AND TREATMENT by E. Diasamidze, M. Diasamidze, K. Zhukov, S. Schneider

“…Modern medicine has a significant, rapidly replenished arsenal of painkillers and methods, most of which are aimed at the suppression of the nociceptive system. …”
Get full text

A Machine Learning Model for Predicting Prognosis in HCC Patients With Diabetes After TACE by Wu L, Chen L, Zhang L, Liu Y, Ouyang D, Wu W, Lei Y, Han P, Zhao H, Zheng C

“…Lastly, the SHapley Additive exPlanations (SHAP) method was used to interpret the final ML model.Results: A total of 636 patients were included. …”
Get full text

EC50 and EC95 of Remifentanil for Inhibiting Bronchoscopy Responses in Elderly Patients During Fiberoptic Bronchoscopy Under Ciprofol Sedation: An Up-and-Down Sequential Allocation... by Lan H, Liu S, Liao Y, Xu B, Lin Y, Wu X, Chen Q, Chen H, Guan X

“…The EC50 and EC95 values of remifentanil required to alleviate the responses to FOB were calculated using Dixon’s up-and-down method for both male and female groups. Probit analysis was used to generate a dose-response curve.Results: Thirty-nine patients (19 males and 20 females) were enrolled. …”
Get full text

Exploring the Role of Allergenic Components in Children with House Dust Mite-Induced Allergic Diseases by Xu Q, Shang Y, Li X, Ran S, Lu M, Cheng L

“…Qiuyan Xu,1,* Yunxia Shang,1,* Xiang Li,1 Shuangqin Ran,1 Min Lu,1 Lei Cheng2,3 1Department of Pediatrics, Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou, People’s Republic of China; 2Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 3International Centre for Allergy Research, Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Cheng, Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People’s Republic of China, Email chenglei@jsph.org.cn Min Lu, Department of Pediatrics, Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, 1 Lijiang Road, Suzhou, 215153, People’s Republic of China, Email samy_lm@163.comPurpose: To investigate the main characteristics of HDM-induced allergic diseases in children and to explore allergen component-specific sensitization patterns, features, and correlations with clinical symptoms.Methods: Serum samples were collected from children with HDM-induced allergic diseases. …”
Get full text

Protective Effects of Gynostemma pentaphyllum Saponins on Liver Injury in Guinea Pigs of Hyperlipemia Based on Oxidative Stress by Tianyi DAI, Donglian LIU, Xingmin QIN, Chengling GAO, Jiayi LI, Hailing KUANG

“…Objective: To observe the protective effects of Gynostemma pentaphyllum saponins (GPs) on liver injury in guinea pigs of hyperlipemia based on oxidative stress. Methods: A total of 32 guinea pigs were randomly divided into a model group, a low dose GPs group (85 mg/kg), a high dose GPs group (170 mg/kg), and a simvastatin group (1.5 mg/kg), with 8 animals in each group. …”
Get full text

Assessment of The Factors Affecting Management of Gender and Sexual Violence Against Women in Rural Communities: A Case Study of Kyanamira Sub County Kabale District. by Tumuheki, Timothy

“…The researcher employed a content analysis method to analyze the data. The emerging themes and opinions were properly analyzed, and compared with the information that was obtained in the literature review. …”
Get full text

Efficacy of Different Acupuncture Techniques for Pain and Dysfunction in Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Jing Sun, Yi Liang, Kai-Tao Luo, Xiao-Mei Shao, Ming-Qi Tu, Xiao-Ting Wu, Fang Liu, Xin-Wei Li, Yi-Dan Chen, Qi-Fei Zhang, Cong-Hua Ji, Rong-Rong Li, Xiao-Yu Li, Fu Xu, Jian-Qiao Fang

“…EA is the most effective method of alleviating pain intensity in treating KOA. …”
Get full text

Utilization of plastic waste in hot mix asphalt using dry mixing processes: Laboratory assessment of airborne microplastics by Thanon Bualuang, Peerapong Jitsangiam, Napat Jakrawatana, Pimpawat Teeratitayangkul, Patipat Vongruang, Chotchanit Thienchai, Pongsakorn Wongchana, Jitinun Prommarin

“…Airborne MCPs in construction environments raise potential health concerns, as prolonged exposure to fine particulate matter has been associated with respiratory inflammation and other adverse health effects. The dry-mixing method, which involves blending plastic waste with heated aggregates before adding the asphalt binder, was analyzed under controlled laboratory conditions across mixing, laying, and in-service phases. …”
Get full text

Insights From a User Experience‐Focused Virtual Study on the Feasibility and Challenges of Decentralized Clinical Trials by Yue Ma, Le Li, Gaili Gao, Huan Zhou, Jianmiao Yang, Jiao Zheng, Li Zheng, Lu Zhang, Min Jiang, Pu Li, Wenjing Zhou, Xia Chen, Ying Wang, Weiyi Zheng, Yan Zhang

“…Pain points, stakeholder requirements, and key challenges were identified; standardized procedures and a user journey map were developed to provide a visual representation of the DCT process, encouraging broader adoption. …”
Get full text

Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors by Shudong Lin, Guanghua Zhu, Juan Xie, Xuanwei Wen, Limin Deng, Sijing Li, Guozhi Liu, Feiyan Wang, Shuangxi Chen, Zijian Xiao

“…Thus, the present study mainly focused on the potential therapeutic effects of BDMC on CAA. Method The 30 male C57BL/6 mice were subjected to chronic treatment with five vascular risk factors (lipopolysaccharide, social stress, streptozotocin, high‐cholesterol diet, and copper‐containing drinking water) for 35 weeks to establish a CAA mouse model. …”
Get full text

Brinzolamide encapsulated β-cyclodextrin-chondroitin sulfate nanocomplexes anchored chitosan/polycaprolactone nanofibers as an ocular insert for glaucoma treatment by Haroon Iqbal, Dengming Zhou, Anam Razzaq, Haiyang Zhang, Run Xiao, Fu Lin, Yuanbo Liang

“…Anti-glaucoma eye drops as a topical dosage form are still considered as a method of choice for glaucoma treatment. However, a short ocular drug residence time of eye drops leads to poor bioavailability of drug which requires repeated dosing. …”
Get full text

Effective Tumor Annotation for Automated Diagnosis of Liver Cancer by Yi-Hsuan Chuang, Ja-Hwung Su, Tzu-Chieh Lin, Hue-Xin Cheng, Pin-Hao Shen, Jin-Ping Ou, Ding-Hong Han, Yi-Wen Liao, Yeong-Chyi Lee, Yu-Fan Cheng, Tzung-Pei Hong, Katherine Shu-Min Li, Yi Lu, Chih-Chi Wang

“…To reveal the effectiveness of individual methods, each method was evaluated on real datasets. …”
Get full text

Modeling the relationship between the moral charter derived from Islamic teachings and performance with the mediating variable of employees' perception by leila jahantigh, Abbas Babaeenezhad, Mohsen Zayandehroudi, saeed sayadi

“…The collection tool in the current research includes the organizational equality perception questionnaire by Astron (2015). …”
Get full text

Comparing the efficacy and safety of three surgical approaches for total hysterectomy (TSATH): protocol for a multicentre, single-blind, parallel-group, randomised controlled trial by Yanzhou Wang, Ying Zheng, Fan Yang, Li Deng, Jianhong Liu, Yonghong Li, Sijing Chen, Wenxi Zhang, Xiaolin You, Jiani Gou, Dan Zi, Xiaoxue Qi

“…This study aims to evaluate postoperative recovery and assess the safety and effectiveness of these three surgical approaches for total laparoscopic hysterectomy.Method and analysis This is a multicentre, randomised, single-blind, three-arm, parallel-group, interventional clinical trial. …”
Get full text

Investigation of truncated replication protein mutant of Canine Circovirus: synergistic interaction with Feline Panleukopenia Virus by Suyao Li, Jialiang Xin, Yi Peng, Haifeng Liu, Ziyao Zhou, Zhijun Zhong, Hualin Fu, Min Yang, Min Yang, Wancheng Li, Ruihu Wu, Guangneng Peng

“…Virus particles were visualized using transmission electron microscopy (TEM), while quantitative polymerase chain reaction (qPCR) assessed viral load. …”
Get full text

A bibliometric analysis of exosomes in aging from 2007 to 2023 by Zenghui Niu, Meiyu Cui, Yingkun Fu, Lingfeng Zhou, Jiali Wang, Jiali Wang, Yan Lei, Xinrong Fan, Qiang Wang, Jing Yang

“…Thery C proposed the method of differential centrifugation and density gradient centrifugation to extract exosomes. …”
Get full text

Feeding challenges in early infancy: the role of reflexes, muscle tone, and developmental milestones by Wiktoria Kowalska, Maria Tuczyńska, Jacek Kwiatkowski, Oskar Komisarek, Ewa Mojs, Mirosław Andrusiewicz, Tomasz Szczapa, Włodzimierz Samborski, Dorota Sikorska, Ewa Baum, Roksana Malak

“…The infants’ reflexes were checked, the muscle tone was palpated, the presence of general movements was visually assessed using Prechtl’s method, then the Sensitivity Assessment of the Stomatognathic Complex (SOWKUT) questionnaire and Albert Infant Motor Scale (AIMS) scale were evaluated. …”
Get full text

Perfil inflamatorio del humor acuoso tras tratamiento asistido por láser de femtosegundo en casos de catarata nuclear by Claudia Palacio-Pastrana, Andric C. Perez-Ortiz, Bani Antonio-Aguirre, Cristina Mendoza-Velásquez, Azyadeh Camacho-Ordóñez, Manuel Ceballos-Reyes, Atzin Robles-Contreras, Virgilio Lima-Gómez

“…The clinical implications of these elevations on visual outcomes warrant future study. …”
Get full text