THE EFFECTIVENESS OF PTPN11 GENE ANALYSIS IN THE PRENATAL DIAGNOSIS OF NOONAN SYNDROME by Güven Toksoy, Fatih Tepgeç, Tuğba Saraç Sivrikoz, İbrahim Halil Kalelioğlu, Selma Demir, Recep Has, Atıl Yüksel, Zehra Oya Uyguner, Seher Başaran

“…PTPN11 association is reported in 2-3% of normal karyotyped fetuses with NT and in >10% when other NS findings are included. Material and Method: PTPN11 analysis with different approaches in 246 normal karyotyped prenatal cases with NS-associated USG findings were retrospectively evaluated. …”
Get full text

Risk factor analysis and predictive nomogram development for in-hospital mortality in patients with ST-segment elevation myocardial infarction by Tahereh Roostami, Maryam Farhadian, Amirhossein Yazdi, Hossein Mahjub

“…Four different feature selection methods were used to select common important variables in the prediction model: Boruta, Recursive Feature Elimination (RFE), Random Forest (RF) and LASSO. …”
Get full text

Short-term outcomes of percutaneous versus subcutaneous fascial flap fixation in cubital tunnel syndrome surgery: A retrospective cohort study by Tianyou Hu, Yujie Bian, Qiankun Wang, Tao Zhou, Hongxiang Zhou

“…Patients were grouped based on the method of fascial flap fixation: subcutaneous (n = 57) or percutaneous (n = 57). …”
Get full text

Effectiveness of Dry Needling versus Trigger Point Compression Release among Patients with Neck Pain - RCT by Saad Tariq, Mamoona Tasleem Afzal, Anam Javed, Iqra Naseem, Nasir Khan, Muhammad Shakir Khan

“…Improvement was assessed through Visual Analog Scale(VAS) and Northwick Park Neck Pain Questionnaire(NPQ). …”
Get full text

Predictors of post caesarean section surgical site infection and referral pattern for caesarean section in a tribal dominant and resource constraint tertiary level health care Cent... by Sona Singh, Neha Jain, Shruti Singh Parihar, Akash Ranjan Singh, Sanjeev Bakshi, Vikrant Kabirpanthi, Nagendra Singh

“…Probability of SSI risk by different factors were estimated using the Kaplan–Meier method, with survival curves compared via log-rank test. …”
Get full text

NEW DIRECTION IN LOCAL THERAPY OF OSTEOARTHRITIS OF THE KNEE JOINT by Ye. S. Tsvetkova, L. N. Denisov

“…Nanoplast forte may be recommended as an efficient and safe method of local therapy of OA of the KJ.…”
Get full text

Abdominal Aorta Screening During Routine Transthoracic Echocardiography in Zanzibar, Tanzania: The Zanzibar Heart Survey by Abukar Mohamed Ali, Khamis Mustafa Khamis, Ghirmay Andemichael, Muhiddin Abdi Mahmoud, Victor Aboyans, Sahrai Saeed

“…AA was measured by the leading-edge-to-leading-edge method from a longitudinal plane, and AAA was defined as an AA diameter of ≥3.0 cm. …”
Get full text

The expository phase of debriefing in clinical simulation: a qualitative study by Giulio Fenzi, Carolina Alemán-Jiménez, Pedro Simón Cayuela-Fuentes, Gabriel Segura-López, Cesar Leal-Costa, José Luis Díaz-Agea

“…However, participants suggested improvements, such as greater dynamism, personalization, and varied presentation methods using videos, skill stations or patient’s-oriented debriefing. …”
Get full text

Apparent diffusion coefficient: a predictor of the efficacy of glucocorticoid therapy in active moderate-severe thyroid eye disease: a retrospective cohort study by Mingqiao Zhang, Xiaohui Zhang, Qian Huang, Liang Liang, Jian Long

“…Abstract Purpose To assess the association between the apparent diffusion coefficient (ADC) of extraocular muscles (EOMs) and the efficacy of glucocorticoid (GC) therapy in patients with active and moderate-severe thyroid eye disease (TED). Method Eighteen active and moderate-to-severe bilateral TED patients (responsive group, n = 8 patients (16 eyes); unresponsive group, n = 10 patients (20 eyes)) who underwent orbital long variable echo‑trains (Resolve)-diffusion tensor imaging (DTI) before GC therapy were retrospectively enrolled. …”
Get full text

Efficient delivery of small RNAs to podocytes in vitro by direct exosome transfection by Tim Lange, Luzia Maron, Claudia Weber, Doreen Biedenweg, Rabea Schlüter, Nicole Endlich

“…This study explores the use of isolated exosomes, directly transfected with fluorescently-labeled small RNAs, for tracking and delivering small RNAs to cultured podocytes. Methods Exosomes were isolated from immortalized murine podocytes and transfected with Cy3-labeled siRNA and miRNA controls using the ExoFect siRNA/miRNA Transfection Kit. …”
Get full text

Observation of the clinical efficacy of disposable fistula snares in the treatment of high anal fistula by Zhong Mingli, Lu Yue

“…[Objectives] To observe the clinical efficacy of disposable fistula snares in the treatment of high anal fistula. [Methods] A total of 60 patients with high anal fistula admitted to the Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from October 2022 to October 2023 were selected as the study subjects, and they were divided into treatment group (n=30, treated with disposable fistula snares) and control group (n=30, treated with low-cut and high-hanging) according to the random number table method. …”
Get full text

How accessible are the websites of health services for people who have had a stroke? by Melita J. Giummarra, Eleanor Brown, Tanya A. Rose, Natasha A. Lannin, Brooke Parsons, Emma Power, On behalf of the Young Stroke Service team

“…Therefore, the present study examined website accessibility of Australian health organisations, and their services, that provide post-stroke healthcare. Method A cross-sectional descriptive study design was used to identify relevant health services in Victoria and South Australia. …”
Get full text

Employing Quantum Entanglement for Real-Time Coordination of Distributed Electric Vehicle Charging Stations: Advancing Grid Efficiency and Stability by Dawei Wang, Hanqi Dai, Yuan Jin, Zhuoqun Li, Shanna Luo, Xuebin Li

“…The model is solved across 96 time intervals using a quantum-classical hybrid method, with benchmark comparisons against MILP and DRL baselines. …”
Get full text

Effect of Co-Administration of Midazolam and Dexmedetomidine on Haemodynamics and Stress Response in Elderly Patients with Non-Small Cell Lung Cancer by Yanjun Zhao, Dongjiao An, Liang Bi

“…Objective This study aimed to evaluate the effect of co-administration of midazolam and dexmedetomidine on hemodynamics and stress response in elderly patients with non-small cell lung cancer (NSCLC).Methods In this prospective, randomized controlled trial, 154 elderly NSCLC patients scheduled for lobectomy in our oncology department from January 2019 to December 2021 were recruited. …”
Get full text

A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-s... by Feng Wang, Minwei Bao, Bo Tao, Fugui Yang, Guangxue Wang, Lei Zhu

“…It could serve as a useful method to assist thoracic surgeons in improving diagnostic accuracy and has the potential to make management decisions.…”
Get full text

Old world camels in Germany: parasitic nematode communities characterized by nemabiome analysis showed reduced anthelmintic efficacy according to the fecal egg count reduction test by Jenny Brachmann, Stefan Fiedler, Hannah Fischer, Jennifer S. Schmidt, Renate Radek, Georg von Samson-Himmelstjerna, Jürgen Krücken

“…This study examined the gastrointestinal parasite fauna of Old World Camels (OWCs) in Germany and evaluated the efficacy of anthelmintic treatment. Methods In total, nine German OWC-keeping farms that dewormed their stock in spring 2023 were examined. …”
Get full text

Improving Explainability and Integrability of Medical AI to Promote Health Care Professional Acceptance and Use: Mixed Systematic Review by Yushu Liu, Chenxi Liu, Jianing Zheng, Chang Xu, Dan Wang

“…Study quality was assessed using the Joanna Briggs Institute critical appraisal checklist and Mixed Methods Appraisal Tool, with only medium- or high-quality studies included. …”
Get full text

Evaluation of the effectiveness of intra-articular administration of highly purified hyaluronic acid in knee osteoarthritis in real clinical practice by V. A. Nesterenko, E. I. Byalik, M. A. Makarov, S. A. Makarov, V. E. Byalik, A. A. Roskidailo, V. N. Amirdzhanova, M. R. Nurmukhametov, A. M. Lila

“…Knee osteoarthritis (kOA) is a common cause of turning for medical advice, associated with chronic pain and disability. One of the methods of OA treatment is the local administration of hyaluronic acid (HA) drugs.Objective: to evaluate the effectiveness of intra-articular (IA) administration of highly purified HA (Armaviskon Plus) in kOA.Patients and methods. …”
Get full text

Using musical pitch interval comparisons to assess cochlear implant frequency-to-place maps by Rebecca M. Lewis, Melanie L. Gilbert, Jordan A. Beim, Andrew J. Oxenham, Charles J. Limb

“…The present study seeks to develop a behavioral assessment metric for how well place-based pitch is represented across the frequency spectrum by evaluating the accuracy with which listeners perceive and compare pitch intervals across different frequency regions.MethodsThe study included two groups: normal-hearing (NH) listeners and CI recipients. …”
Get full text

Core Stabilization Exercise on the Lumbar Lordosis and Pelvic Inclination Among Chronic Nonspecific Low Back Pain Patients by Leo R athinaraj Antony Soundararajan

“…DIERS Formetric 4D spine and posture analyzer were used to assess spinal alignment using the light-optical scanning method on the back of patient in standing position. …”
Get full text