Comparison of myopia-related behaviors among Chinese school-aged children and associations with parental awareness of myopia control: a population-based, cross-sectional study by Chaoying Ye, Chaoying Ye, Chaoying Ye, Yujie Wang, Yujia Liu, Yujia Liu, Yujia Liu, Xingxue Zhu, Xingxue Zhu, Xingxue Zhu, Jianmin Shang, Jianmin Shang, Jianmin Shang, Xiaomei Qu, Xiaomei Qu, Xiaomei Qu

“…Samples were equally allocated to each subgroup of city tiers, children’s age groups, and children’s refractive statuses. …”
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Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort by Valériane Leroy, Anandi Sheth, Julie Jesson, Jean Jacques Koffi, Antoine Jaquet, François Dabis, Didier Koumavi Ekouevi, Karen Malateste, Olivia Keiser, Lehila Bagnan, Simon Boni, Madeleine Amorissani Folquet, Mariam Sylla, Olivier Marcy, Raoul Moh, Gildas Boris Hedible, Sophie Desmonde, Joycelyn Dame, Agatha David, Madeleine Amorissani-Folquet, Sylvie N'Gbeche, Elom Takassi, François Tanoh Eboua, Kouadio Kouakou, Lehila Bagnan Tossa, Caroline Yonaba, Jocelyn Dame, Sylvie Marie N’Gbeche, Fatoumata Dicko Traore, Oliver Ezchechi, Rosemary Audu, Charlotte Bernard, Caroline Couturier, Marie Kerbie Plaisy, Elodie Rabourdin, Thierry Tiendrebeogo, Désiré Dahourou, Emile Sodinyessi, Jean-Claude Azani, Kadidja Diarra, Maika Bengali, Abdoulaye Cissé, Guy Gnepa, Eric Komena, Séverin Lenaud, Eulalie Kangah, Igho Ofotokun, Cecile Delille Lahiri, Noëlle Benzekri, Geoffrey Gottlieb

“…Introduction We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa.Methods We included all patients aged 0–24 years on ART from nine clinics in Côte d’Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. …”
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Hand Grip Strength Cut‐Off Points as a Discriminator of Sarcopenia and Sarcopenic Obesity: Results from the ELSA‐Brasil Cohort by Clarice Alves Santos, Helena Fraga Maia, Francisco José Gondim Pitanga, Maria da Conceição Chagas deAlmeida, Maria de Jesus Mendes daFonseca, Estela Mota Leão deAquino, Letícia de Oliveira Cardoso, Rosane Harter Griep, Sandhi Maria Barreto, Claudia Kimie Suemoto, Paulo Lotufo, Isabela Bensenor, Sheila Maria Alvim deMatos

“…Conclusions The results suggest that HGS is a good discriminator of sarcopenia and sarcopenic obesity, capable of achieving superior or equal performance to muscle mass biomarkers, especially in middle‐aged adults.…”
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[18F]FMISO PET in metastatic neuroendocrine tumours: a pilot study by David Chan, Alice Conner, Nick Pavlakis, Elizabeth Bailey, Alireza Aslani, Kathy Willowson, Connie Diakos, Elizabeth Bernard, Stephen Clarke, Alexander Engel, Paul Roach, Dale Bailey

“…The presence of hypoxia may have prognostic and therapeutic implications, and was evaluated in these lesions using the PET hypoxia imaging biomarker [18F]FMISO. Methods: Prospective pilot study in patients with metastatic NENs with at least one DONUT lesion (central [68Ga]DOTATATE non-avidity). [18F]FDG and [18F]FMISO scans were acquired within 60 days of the [68Ga]DOTATATE PET/CT. [18F]FMISO scans were acquired as a dynamic scan over 20 mins from injection with a delayed image at 2 hours. …”
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Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population by Ashok Kumar Yadav, Jaskiran Kaur, Prabhjot Kaur, Kajal Kamboj, Yoshinari Yasuda, Masaru Horio, Arnab Pal, Nusrat Shafiq, Nancy Sahni, Harbir Singh Kohli, Seiichi Matsuo, Vivek Kumar, Vivekanand Jha

“…Results: A total of 412 subjects (55% with CKD), average age 47 ± 11 years with an equal distribution of males and females were enrolled. …”
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Combination of Essential Oils and Extracts Enriched with Tocopherols in Diet of Holstein Steers and Its Effect on Ruminal Fermentation, Antioxidant and Anti-Inflammatory Response,... by João Gustavo Weschenfelder Wandscheer, Natalia Turcatto, Guilherme Luiz Deolindo, Mateus Henrique Signor, Alexandro Fritzen, Marcelo Vedovatto, Camila Ten Kathen Jung, Gilberto Vilmar Kozloski, Ana Carolina Hadlich Xavier, Roger Wagner, Bianca Fagan Bissacotti, Priscila Marquezan Copetti, Aleksandro Schafer da Silva

“…Background: This experiment evaluated whether the combination of essential oils (thyme, rosemary, orange) with extracts of <i>Cinnamomum</i> and <i>Quillaja saponaria</i> (enriched with tocopherols) in steers’ diet has positive effects on the health, digestibility, growth, oxidative stress, and fatty acid profile of meat. Methods: The experiment included 24 Holstein steers, divided into two groups, randomly divided (treated = phytogenic mixture (n = 12); control = monensin (n = 12)), undergoing a growth phase of 120 days and 90 days of finishing in individual pens, with a monthly collection of blood, rumen fluid, feces, and feed. …”
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Normal tissue complication probability modeling for late rectal bleeding after conventional or hypofractionated radiotherapy for prostate cancer by Christian A.M. Jongen, Ben J.M. Heijmen, Wilco Schillemans, Andras Zolnay, Marnix G. Witte, Floris J. Pos, Ben Vanneste, Ludwig J. Dubois, David van Klaveren, Luca Incrocci, Wilma D. Heemsbergen

“…Purpose: To develop a single NTCP model for grade ≥ 2 late rectal bleeding (G2 LRB) after conventional or hypofractionated radiotherapy for prostate cancer. Methods and Materials: The development dataset consisted of prostate cancer patients (n = 656) previously randomized to conventional (39 x 2 Gy) or hypofractionated (19 x 3.4 Gy) external beam radiotherapy with N = 89 G2 LRB cases. …”
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Machine learning based assessment of hoarseness severity: a multi-sensor approach centered on high-speed videoendoscopy by Tobias Schraut, Anne Schützenberger, Tomás Arias-Vergara, Melda Kunduk, Matthias Echternach, Stephan Dürr, Julia Werz, Michael Döllinger

“…IntroductionFunctional voice disorders are characterized by impaired voice production without primary organic changes, posing challenges for standardized assessment. Current diagnostic methods rely heavily on subjective evaluation, suffering from inter-rater variability. …”
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Identifying key components of a global conceptual framework for adolescent nutrition: Review, nominal group technique and youth co-design by Marion L Roche, Deepika Sharma, Sarah Kehoe, Sara Estecha-Querol, Catharine A K Fleming, Amir A Samnani, Milca J Cameseria, Dipty Chowdhury, Webster Isheanopa Makombe, Amanda Murungi Eunice, Muhammad Sarim Raza, Miriam Shindler, Kesso G van Zutphen-Küffer, Stephanie V Wrottesley

“…This paper presents the methods used to identify the need for and to prioritise the key components of a new framework.Methods A literature review was conducted to identify and summarise available frameworks for adolescent nutrition (10–19 years). …”
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Explainable clinical diagnosis through unexploited yet optimized fine-tuned ConvNeXt Models for accurate monkeypox disease classification by Muhammad Waqar, Zeshan Aslam Khan, Shanzey Tariq Khawaja, Naveed Ishtiaq Chaudhary, Saadia Khan, Khalid Mehmood Cheema, Muhammad Farhan Khan, Syed Sohail Ahmed, Muhammad Asif Zahoor Raja

“…A number of pre-processing and data augmentation methods have also been assessed and adjusted with regard to computing time and performance. …”
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Critical role of Oas1g and STAT1 pathways in neuroinflammation: insights for Alzheimer’s disease therapeutics by Zhixin Xie, Linxi Li, Weizhong Hou, Zhongxi Fan, Lifan Zeng, Limin He, Yunxiang Ji, Jingbai Zhang, Fangran Wang, Zhou Xing, Yezhong Wang, Yongyi Ye

“…Machine learning algorithms were applied to DEGs, and genes selected by both methods were identified as hub genes, with ROC curves used to evaluate their diagnostic accuracy. …”
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A comparative study on the clinical efficacy of laser hemorrhoidoplasty and rubber band ligation for grade Ⅱ to Ⅲ internal hemorrhoids by Jin Lei, Wu Jiong, Wang Zhenyi, Qin Kaijian, Wu Renjie

“…[Conclusion] In conclusion, both LHP and RBL are viable surgical methods for effectively treating gradeⅡ to Ⅲ internal hemorrhoids. …”
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Preemptive Analgesia with Nonsteroidal Anti-Inflammatory Drugs in the Perioperative Period by M. S. Danilov, I. S. Simutis, D. S. Salygina, E. G. Polovtsev, A. A. Syrovatsky, V. A. Ratnikov, A. A. Bogatikov, A. E. Karelov

“…Efficacy and safety were assessed using a visual analog scale (VAS), patient’s need in opioid analgesics, laboratory parameters (serum levels of cortisol, cystatin C, CBC, coagulogram, TEG) and instrumental methods (algesimetry — qNOX).Results. …”
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Abnormal Brain Functional Connectivity in Patients with Chronic Obstructive Pulmonary Disease and Correlations with Clinical and Cognitive Parameters by Han KI, Yeo Y, Jo HJ, Jo MJ, Park Y, Park TS, Jung SJ, Bae JH, Jang SH, Choi J, Park DW, Kim TH

“…In this study, we used resting-state functional magnetic resonance imaging to investigate brain functional connectivity (FC) abnormalities in patients with COPD and explored the correlation between abnormal FC and COPD-related clinical parameters.Methods: Forty-one patients with COPD, without a definite diagnosis of cognitive impairment or depression, and 30 age- and sex-matched controls were recruited. …”
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Human Mesenchymal Stem Cell-Derived Exosomes as Engineering Vehicles of Daunorubicin for Targeted c-Mpl+ AML Therapy by Li C, Wen Y, Wang J, Li L, He Y, Cheng Y, Chen J, Huang J, Ouyang C, Liu Y, Zhou R, Chen H, Li F, Guo Q, Chen Y, Chen C, Zhang Q

“…This study aimed to develop a type of targeted exosomes (Exos) capable of delivering anticancer drugs directly to c-Mpl+ AML cells.Methods: Human umbilical cord mesenchymal stem cells (hUCMSCs) were isolated as the source of Exos. …”
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MRI Features and Neutrophil-to-Lymphocyte Ratio (NLR)-Based Nomogram to Predict Prognosis of Microvascular Invasion-Negative Hepatocellular Carcinoma by Wei Y, Huang X, Pei W, Zhao Y, Liao H

“…Yunyun Wei,1,2,&ast; Xuegang Huang,3,&ast; Wei Pei,1,2,&ast; Yang Zhao,1,2 Hai Liao1,2 1Department of Medical Imaging Center, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People’s Republic of China; 2Guangxi Key Clinical Specialty (Medical Imaging Department), Nanning, Guangxi, 530021, People’s Republic of China; 3Department of Infectious Diseases, The First People’s Hospital of Fangchenggang City, Fangchenggang, Guangxi, 538021, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hai Liao, Department of Medical Imaging Center, Guangxi Medical University Cancer Hospital, No. 71 hedi Road, Nanning, Guangxi, 530021, People’s Republic of China, Tel +86-771-5334951, Email 42442427@qq.comPurpose: This study aimed to develop a novel nomogram to predict recurrence-free survival (RFS) for microvascular invasion (MVI)-negative hepatocellular carcinoma (HCC) patients after curative resection.Patients and Methods: A total of 143 pathologically confirmed MVI-negative HCC patients were analyzed retrospectively. …”
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Proposal and Verification of New Revised Criteria for ABPA/ABPM Diagnosis by Cai R, Ge H, Liu B, Tang Y, Wang J, Chen X, Liu B, Hu X, Deng S, Li H, Dai L, Tang J, Wu C, Gong X, Wang G, Li X, Feng J

“…In 2021, Asano et al introduced new diagnostic criteria for allergic bronchopulmonary mycosis (ABPM), which were found to improve diagnostic sensitivity compared to existing criteria, but the specificity was lower.Methods: To develop revised scoring criteria for ABPA/ABPM diagnosis, delphi surveys were conducted with two rounds in 14 experts. …”
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Outcome Following Chest Tube Removal with Respect to Phase of Respiration in Chest Trauma Patients: A Randomised Controlled Trial by Ritesh Kumar, Sandeep Chauhan, Mahavir Singh, Mohammed Faiz, Deepak, Gaurav Sharma, Manish Kumar Yadav, Sanjay Marwah

“…After evacuation of pleural contents, removal of chest tube is equally important since its careless removal can cause serious complications like Recurrent Pneumothorax (RP) and even lung collapse. …”
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Berberine Intervention Mitigates Myocardial Ischemia-Reperfusion Injury in a Rat Model: Mechanistic Insights via miR-184 Signaling by Yang H, Cao G, Li X, Zhao Z, Wang Y, Xu F

“…Additionally, the study explored the role of the miR-184/NOTCH1 signaling pathway in mediating these effects.Methods: Male Wistar rats were randomly assigned to five groups: sham-operated control, I/R injury, I/R treated with berberine, I/R treated with inhibitor NC and I/R treated with a miR-184 inhibitor. …”
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The role of the control of “life’s essential 8” for prevention on heart failure and all-cause mortality in patients with hypertension: the Kailuan cohort study by Jing Wang, Shuilin Wu, Liuxin Li, Jing Wu, Shiqiu Meng, Xueying Qin, Xin Chen, Shoulin Wu, Jie Shi, Yanping Bao, Feng Wang

“…However, evidence on the beneficial effects and necessity of LE8 control is still lacking, especially for hypertension. Methods The study population was drawn from the Kailuan cohort, hypertensive population at baseline with the non-hypertensive population matched 1:1 according to age and sex were involved in this analysis. …”
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