Network pharmacology-based approach to research the effects and mechanisms of Salvia Miltiorrhiza injection against idiopathic pulmonary fibrosis by Liangyu Chen, Liangyu Chen, Haobo Lin, Haobo Lin, Haobo Lin, Linmang Qin, Linmang Qin, Linmang Qin, Guangfeng Zhang, Guangfeng Zhang, Guangfeng Zhang, Peisheng Chen, Zebo Jiang, Pan Xu, Donghui Huang, Xiao Zhang, Xiao Zhang

“…This study aims to investigate the therapeutic effects and mechanisms of SM injection in treating IPF.MethodsActive components and targets of SM were acquired from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database, while IPF-associated genes were obtained from the DisGeNET database. …”
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The Effect of Rosa Foetida Extract along with Self-Care Education on Primary Dysmenorrhea: A Prospective Randomized Clinical Trial by Fatemeh Shabani, Shabnam Omidvar, Parvin Sajadi Kaboudi, Hajar Pasha, Soraya Khafri, Hossein Najafzadehvarzi, Fatemeh Nasiri-Amiri, Mahbobeh Faramarzi, Zinatossadat Bouzari

“…The purpose of this study was to determine the effect of Rosa Foetida extract along with self-care behaviors on primary dysmenorrhea. Methods: A randomized clinical trial was conducted on 135 students residing in dormitories. …”
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Lack of pre-movement facilitation as neurophysiological hallmark of fatigue in patients with Parkinson's disease: A single pulse TMS study by Antimo Buonocore, Celeste Cafaro, Ciro De Luca, Giovanna Vermiglio, Giovanna Sepe, Giuseppe Rocco, Marco Aiello, Andrea Soricelli, Michele Papa, Carlo Cavaliere, Giovanni Cirillo

“…Recent evidence suggests that deficits in cortical motor preparation processes may contribute to PD-related fatigue. Methods: This study investigated premovement facilitation (PMF), a marker of corticospinal excitability during motor preparation, in 20 healthy subjects (HS) and 28 PD patients, subdivided into those with fatigue (PDwF, n = 14) and without fatigue (PDwoF, n = 14). …”
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Association between atherogenic index of plasma and physical dysfunction: a cross-sectional study of middle-aged and older adults in China by Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Yun Chang, Yun Chang, Yun Chang, Yun Chang, Hechen Shen, Hechen Shen, Hechen Shen, Hechen Shen, Hechen Shen, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Xiaoyu Liang, Xiaoyu Liang, Xiaoyu Liang, Xiaoyu Liang, Wenqing Gao, Wenqing Gao, Wenqing Gao, Wenqing Gao, Wenqing Gao

“…The restricted cubic splines were used to examine possible non-linear associations and visualize the dose–response relationship between AIP and physical dysfunction. …”
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Validation of the traditional Chinese version of the Sinus and Nasal Quality of Life Survey (SN-5) for children by Wan-Yu Lai, David J. Kay, Chang-Ching Wei, Fen-Wei Huang, Kai-Li Liang, Hung-Rong Yen

“…We translated the SN-5 into traditional Chinese and evaluated validity and reliability. Methods: From December 2016 to December 2017, healthy volunteers and children with persistent sinonasal symptoms were enrolled. …”
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Evolving multimorbidity patterns among ageing adults with cardiovascular disease continuum in Southwest China: A longitudinal cohort study by Xiaoya Qi, Ziyue Zhang, Meng Jia, Yangping Zhang, Shuang Feng, Ruixue Bai, Siyao Wang, Jinning Mao, Shu Su

“…The construction of the multimorbidity network was based on Spearman correlation analyses to visualize the evolution of gender differences. Odds ratios (ORs) for developing multimorbidity in CVDC in compared to non-CVDC were calculated. …”
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Comparison of seropositive and seronegative rheumatoid arthritis patients using or about to be initiated with biological DMARDS by Zehra Özsoy, Şerife Asya Germe, Gizem Ayan, Güllü Sandal Uzun, Mustafa Ekici, Erdinç Ünaldı, Levent Kılıç, Ali Akdoğan, Şule Apras Bilgen, Sedat Kiraz, Ali İhsan Ertenli

“…This study aimed to compare the demographic, clinical characteristics, treatment choices, and treatment responses of seronegative (SN) and seropositive (SP) RA patients who were receiving or newly started biological treatment. Methods: The files and records of patients registered with Hacettepe University Biological Database with RA diagnosis who were planned to use biological disease-modifying antirheumatic drugs (b-DMARDs) between 2010-2024 were scanned. …”
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Home-based self-administered transcranial direct current stimulation for women affected by primary dysmenorrhoea in Northeastern Brazil: a protocol study by Thiago Anderson Brito De Araújo, Edson Silva-Filho, Rodrigo Pegado, Tatiana Camila de Lima Alves da Silva, Yvinna Tamiris Rodrigues, Paloma Cristina Alves de Oliveira, Ervinas Bernatavicius, Alexander Anthony Cook, Emilè Radytè, Maria Thereza Micussi

“…Primary outcome will be pain according to visual analogue scale. Quality of life, premenstrual symptoms screening, depression, anxiety, physical performance, electroencephalography and participants’ satisfaction will be the secondary outcomes. …”
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Time-Intensity Curve Analysis of Contrast-Enhanced Ultrasound for Non-Ossified Thyroid Cartilage Invasion in Laryngeal Squamous Cell Carcinoma by Milda Pucėtaitė, Dalia Mitraitė, Rytis Tarasevičius, Davide Farina, Silvija Ryškienė, Saulius Lukoševičius, Evaldas Padervinskis, Valdas Šarauskas, Saulius Vaitkus

“…<b>Objective:</b> This study aimed to assess the diagnostic value of contrast-enhanced ultrasound (CEUS) time–intensity curve (TIC) parameters in detecting non-ossified thyroid cartilage invasion in patients with laryngeal squamous cell carcinoma (SCC). <b>Methods</b>: A CEUS TIC analysis was performed on 32 cases from 27 patients with histologically confirmed laryngeal SCC. …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…., from self-directed to specialized care) for caregivers of youth with chronic illnesses. <b>Methods</b>: The review methodology was co-designed with four caregivers. …”
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Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

“…<b>Introduction</b>: This study aimed to capture the early metabolic changes before osteoporosis occurs and identify metabolomic biomarkers at the osteopenia stage for the early prevention of osteoporosis. <b>Materials and Methods</b>: Metabolomic data were generated from normal, osteopenia, and osteoporosis groups with 320 participants recruited from the Nicheng community in Shanghai. …”
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Maintenance of CPR skills among nursing students trained using Resuscitation Quality Improvement® program by Marilyn H. Oermann, Yolanda M. VanRiel, Robin W. Wagner, Kelli D. Whittington, Manisa Baker, Debra E. Stieve, Patrick C. Crane, Carol A. Vermeesch

“…Objective: The objective of this multisite longitudinal study was to examine the maintenance of adult and infant compressions and ventilation skills by nursing students at 3 and 6 months following practice with real-time feedback using the RQI® program. Methods: The effectiveness of brief practice of CPR skills at the RQI® simulation station on the maintenance of skills was analyzed with 238 nursing students from six universities across the United States. …”
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Predicting diabetic retinopathy stages using a simple nerve conduction measuring device, DPNCheck®: a retrospective observational study by Mayu Sakai, Mayu Sakai, Mayu Sakai, Takehiro Kato, Takehiro Kato, Takuma Ishihara, Ken Takao, Ken Takao, Tokuyuki Hirose, Tokuyuki Hirose, Sodai Kubota, Sodai Kubota, Saki Kubota-Okamoto, Saki Kubota-Okamoto, Toshinori Imaizumi, Toshinori Imaizumi, Yoshihiro Takahashi, Yoshihiro Takahashi, Masami Mizuno, Masami Mizuno, Takuo Hirota, Takuo Hirota, Yukio Horikawa, Yukio Horikawa, Hirokazu Sakaguchi, Hirokazu Sakaguchi, Shin Tsunekawa, Daisuke Yabe, Daisuke Yabe, Daisuke Yabe

“…Aims/introductionDiabetic retinopathy (DR) often remains asymptomatic until it reaches advanced stages, when delayed treatment can lead to irreversible visual impairment. To promote timely ophthalmology visits, this study investigated the utility of a simple nerve conduction device, DPNCheck®, as a predictor of DR severity. …”
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N-Butyl-2-Cyanoacrylate Adhesive Versus Absorbable Tacks in Laparoscopic Groin Hernia Repair: A Multicenter Randomized Clinical Trial by Clayton C. Petro, MD, Benjamin K. Poulose, MD, Michael J. Rosen, MD, Alfredo M. Carbonell, II, DO, Adel G. El-Ghazzawy, MD, Jeremy A. Warren, MD, Emanuele Lo Menzo, MD, Ajita S. Prabhu, MD, David M. Krpata, MD, Samuel Szomstein, MD, Vimal Narula, MD, Crystal F. Totten, MD, Kelly R. Haisley, MD, Andrew C. Bernard, MD, Henrik O. Berdel, MD, Jessica K. Reynolds, MD, Zachary D. Warriner, MD, John S. Roth, MD

“…The primary outcome was improvement in pain (visual analog scale [VAS]) at 6 months. The noninferiority margin was 0.9 (α = 0.025; β = 80%). …”
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Utilization of magnification devices in Vietnam’s dental practice and education: an online survey by Minh-Hieu Nguyen Tran, Anh Huynh Bui, Lan-Anh Hoang Le, Thuy-Trang Thi Huynh, Phuong-Doan Phan, Thuan-Loc Tran, Nguyen-Tra-Mi Le, Thu-Tra Nguyen, Hoang-Vinh Le, Dai-Phong Lam, Quoc-Viet Lam, Tran-Lan-Khue Pham, An-Tran Pham, Van-Khoa Pham

“…This study aimed to assess magnification device utilization in Vietnamese dental practice and education, with a pioneering focus on 3D-DOMs. Methods An online, questionnaire-based observational survey was conducted from October to December 2024. …”
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Clinical and mycological investigations of post‐COVID‐19 acute invasive fungal sinusitis by Samah Mahmoud Eldsouky, Amany K. Shahat, AL‐Shaimaa M. AL‐Tabbakh, Shaymaa M. Abd El Rahman, Yasmin M. Marei, Lina Abdelhady Mohammed, Ola Samir El‐Shimi, Dina Saad Abdelmotaleb, Yomna Mohammed Marei, Mohamed Sabry Abd Elraheam Elsayed

“…Headache and facial pain, ophthalmoplegia, visual loss, and blindness represented 100%, 66.7%, 90%, and 53.3% of the cases, respectively. …”
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Neosols, relict paleosols, and alterites in the Transmexican Volcanic Belt, Morelos state: Characterization and regional spatial distribution by Jorge Enrique Gama-Castro, David Flores-Román, Elizabeth Solleiro-Rebolledo, Carolina Jasso-Castañeda, Ernestina Vallejo-Gómez, Ana María Rocha-Torrallardona, José Luis Villalpando-González

“…In our study, the interpretation of thematic cartography and the application of sophisticated methods like remote sensing and laboratory automated image analyses combined with field transects, provided a unique set of tools for generating and synthesizing data. …”
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Levels of physical activity in a large international cohort of patients with systemic lupus erythematosus by Laurent Arnaud, Matteo Piga, Manuel Francisco Ugarte-Gil, Christelle Sordet, Philippe Mertz, Luc Pijnenburg, Marina Rinagel, Lou Kawka, Sophie Geneton, Julien Blaess, Timothée Mischler, Juan C Sarmiento-Monroy

“…The aim of this study was to assess PA level and characteristics in a large international cohort of patients with SLE.Methods PA was assessed in metabolic equivalent of tasks (METs) using the International Physical Activity Questionnaire (IPAQ) and classified into three levels: low, moderate and high PA. …”
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Investigating the effects of mobile bottom fishing on benthic carbon processing and storage: a systematic review protocol by Stacey L. Felgate, John Aldridge, Stefan G. Bolam, Sarah Breimann, Emil de Borger, Jolien Claes, Jochen Depestele, Graham Epstein, Clement Garcia, Natalie Hicks, Michel Kaiser, Jack H. Laverick, Gennadi Lessin, Finbarr G. O’Neill, Sarah Paradis, Ruth Parker, Ryan Pereira, Alex J. Poulton, Claire Powell, Craig Smeaton, Paul Snelgrove, Justin Tiano, Johan van der Molen, Sebastiaan van de Velde, Marija Sciberras

“…Results will be reported in narrative and quantitative syntheses using a variety of visual tools including forest plots. Meta-analysis will be conducted where sufficient data exists.…”
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Mapping Antarctic Blue Ice Areas With Sentinel-2A/B Images and LightGBM Model by Xiaolong Teng, Jiahui Xu, Xiangbin Cui, Guitao Shi, Zhengyi Hu, Qingyu Gu, Bailang Yu, Jianping Wu, Yan Huang

“…While satellite remote sensing is effective in mapping BIAs, traditional methods rely on limited spectral bands and linear models with inherent limitations. …”
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