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21421
Identification and Validation of Ferroptosis Related Genes in Ischemic Stroke and Its Effect on the Peripheral Immune Landscape
Published 2024-12-01“…Yan Chen,1,* Yanmei Zhu,1,* Cong Huang,2 Youyang Qu,1 Yulan Zhu1 1Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150080, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150080, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yulan Zhu, Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, No. 246, Xuefu Road, Nangang District, Harbin, Heilongjiang, 150081, People’s Republic of China, Email ylz1111@outlook.comBackground: This research utilized a combination of gene databases associated with ferroptosis and online gene expression data from ischemic stroke samples to pinpoint ferroptosis-related genes (FRGs) in ischemic stroke cases.Methods: By employing Random Forest (RF) and Support Vector Machine (SVM) models based on these genes, an overlap of genes from both models was identified as “Hub” genes. …”
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21422
Frameworks describing the transition to open labour employment for persons with mild and moderate intellectual disability: a scoping review protocol
Published 2024-07-01“…Introduction Persons with mild and moderate intellectual disability (MMID) have the right to participate in all aspects of society and be afforded equal opportunities to realise their full potential. …”
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21423
Circulating miR-147b as a diagnostic marker for patients with bacterial sepsis and septic shock.
Published 2021-01-01“…<h4>Conclusions</h4>The plasma miR-147b may be an useful biomarker independently or in combination with PCT to support clinical diagnosis of sepsis and equally prognosis of patients with septic shock.…”
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21424
Outcomes following use of a standard antibiotic protocol in the management of maxillofacial trauma patients
Published 2020-10-01“…Purpose: To evaluate the effectiveness of a standard antibiotic regimen protocol in the management of maxillofacial trauma patients. Materials and methods: The study sample included patients with at least one facial fracture and managed by either closed (CR/MMF) or open reduction (ORIF) by the Oral and Maxillofacial Surgery service. …”
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21425
Perpetual Peace: An Analysis of Kant’s Theory of Peace in Terms of The Islamic Worldview
Published 2022-12-01“…This research was library research, and the methods used were descriptive, analytical, and comparative. …”
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21426
Child sexual abuse awareness among parents visiting pediatric outpatient hospital services in Southern India
Published 2025-01-01“…Out of the 273 participants, we had equal representation from both genders. Sixty-three percent were from rural residential backgrounds. …”
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21427
Effect of Fenugreek Seeds in Maternal Diet on Some Features of Newborn Pups in Albino Mice
Published 2021-12-01“…The present study aimed to investigate the effects of 5% raw fenugreek seed and its boiled aqueous extract containing diet on adult female mice, for 2 weeks before mating, to evaluate fertility, and some features of newborn pups. Materials and Methods: A total of 90 adult female mice randomly and equally were divided into three groups. …”
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21428
Unraveling Demographic Patterns in Hepatitis B Clinical and Laboratory Profiles: Insights From a Ghanaian Cohort: A Retrospective Study
Published 2025-04-01“…This study assessed the impact of age and gender on HB disease manifestations in a Ghanaian population. Methods This retrospective study evaluated 569 patients at Tamale Teaching Hospital. …”
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21429
Assessment of peri-implant tissues in posterior implants placed using flapless approach: A clinicoradiographic study
Published 2024-08-01“…Therefore, the purpose of this study was to evaluate and compare the hard- and soft-tissue changes in immediate and delayed posterior implants with a flapless approach. Materials and Methods: With an equal allocation ratio, the study included 46 patients requiring implant treatment in the posterior segment, including the premolars and molars. …”
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21430
Mortality inequalities at retirement age between migrants and non-migrants in Denmark and Sweden
Published 2024-03-01“…RESULTS: Non-European-born migrants had the survival advantage in both countries, but equal or higher lifespan inequality at retirement. …”
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21431
CXCR2 Activated JAK3/STAT3 Signaling Pathway Exacerbating Hepatotoxicity Associated with Tacrolimus
Published 2024-12-01“…The aim of this study was to investigate the mechanism of tacrolimus-induced hepatotoxicity and provide reference for drug development target.Methods: In this study, biochemical analysis, pathological staining, immunofluorescent staining, immunohistochemical staining, transcriptomic analysis, Western blotting was used to investigate the mechanism of tacrolimus-induced hepatotoxicity in gene knockout mice and Wistar rats.Results: In gene knockout mice, compared to wild-type mice, CXCR2-deficiency alleviated tacrolimus-induced hepatotoxicity (P…”
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21432
Thriving in golden years: Promoting psychological well-being for healthy ageing in India
Published 2025-03-01“…Because, with increasing age, as the health status among individual's decline, promoting a positive self-perception of ageing is equally important in facilitating healthy ageing as that of promoting healthier lifestyle.…”
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21433
Follicular mycosis fungoides - A report of four Indian cases
Published 2009-01-01“…<b> Aims:</b> To describe the clinical and pathological features of FMF. <b> Materials and Methods:</b> All cases of FMF between January and December 2007 were retrieved. …”
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21434
Protective Effect of Fenugreek Supplementation against Mercury Toxicity on Sperm Parameters, Serum Testosterone and Testicular Tissue in the Rat
Published 2023-09-01“…Background and objectives:The purpose of the current study was to investigate the effects of fenugreek supplementation against toxic effect of mercuric chloride (HgCl2)on Body weight (B.W), testis and epididymis weight, some sperm parameters, serum testosterone, serum MDA, and testis histology in the rat.Methods: Twenty eight male albino rats weights ranging from 254 to 302 gm and were divided randomly and equally into 4 groups. …”
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21435
Effects of macrolide antibiotics on blood inflammatory mediators and organ damage markers in lipopolysaccharide-induced pulmonary damage rats
“…<p> <b>Materials and Methods:</b> Total 198 Sprague-Dawley rats were used. …”
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21436
Fear of negative evaluation biases social evaluation inference: evidence from a probabilistic learning task.
Published 2015-01-01“…High FNE individuals are equally sensitive to learning positive or negative evaluation, which although objectively more accurate, may have detrimental effects on mental health.…”
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21437
503 A novel approach to developing and validating a predictive model of functional recovery for adults with stroke in post-acute rehabilitation
Published 2025-04-01“…Objectives/Goals: To use patient-level Center for Medicare and Medicaid Services (CMS) mandated quality metrics for inpatient rehabilitation facilities (IRFs) to develop and validate predictive models of functional recovery and interactions of baseline characteristics with therapy time. Methods/Study Population: Retrospective cohort study of a national US sample of ~40,000 adults with a primary diagnosis of stroke admitted to IRFs in 2023. …”
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21438
Microscopic evaluation of the effect of low-level laser therapy on platelet-rich fibrin: An in vitro study
Published 2024-09-01“…The PRF samples were vertically cut into two equal parts and divided into two groups: Group I (without laser treatment) and Group II (treated with LLLT). …”
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21439
Descriptive transcriptome analysis of tendon derived fibroblasts following in-vitro exposure to advanced glycation end products.
Published 2022-01-01“…We propose to complete a descriptive approach to pathway profiling to broaden our mechanistic understanding of cell signaling events that may contribute to the development of tendon pathology.<h4>Methods</h4>Rat Achilles tendon fibroblasts were treated with glycolaldehyde-derived AGEs (200μg/ml) for 48 hours in normal glucose (5.5mM) conditions. …”
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21440
The effect of angle between the graft and coronary artery on volumetric flow rate through the anastomosis
Published 2019-03-01“…The aim – to determine the optimal value of the angle between the graft and the coronary artery, which can ensure maximum volumetric blood flow through the created coronary anastomosis. Materials and methods. The study was carried out with porcine vessels. …”
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