INHIBITORY ACTIVITY OF BIOACTIVE COMPOUNDS IN BLACK SEA CUCUMBER (HOLOTHURIA ATRA) AGAINST FALCIPAIN-2 PROTEIN IN PLASMODIUM FALCIPARUM AS ANTIMALARIA BASED ON IN SILICO STUDY by Alifiah Wahyu Nur Fadilah, Prawesty Diah Utami, Nita Pranitasari

“…Objective: to determine the inhibitory effects of active compounds in Holothuria atra on the development of Plasmodium falciparum based on in silico studies. Method: The research design used was a one-shot experimental study, contained several stages, including protein and ligand preparation; prediction of bioactive compound potential and target protein; molecular docking and visualization of docking results; and prediction of drug-likeness and absorption, distribution, metabolism, excretion, toxicity (ADMET) Results: Based on the test results, the active compounds are chlorogenic acid, catechin, rutin, coumaric acid, pyrogallol, and ascorbic acid, show inhibition of Falcipain-2, which is used to degrade hemoglobin and erythrocytes in the acidic digestive vacuole. …”
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Enhancing the Green Construction Performance Resilience in Infrastructure Projects: A Complexity Perspective by Yikun Su, Junhao Liu, Zhizhe Zheng

“…A series of indicators for quantifying GCPR are constructed and applied, enabling the quantification of green construction performance resilience in infrastructure projects. An optimization method for GCPR based on genetic algorithms is proposed. …”
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Experimental Investigation on Two-phase Flow Pattern of Hydrocarbon Refrigerants in Shell Side of Helically Baffled Shell and Tube Heat Exchanger by 杨果成, 丁国良, 陈杰

“…In this study, the two-phase flow patterns of propane and ethane/propane mixtures in the shell side of a helically baffled heat exchanger were tested using a visualization experimental method. The test results show that with the increase of vapor quality, the experimental observations sequentially included stratified flow, stratified-spray flow, and spray flow; as the mass flux of propane increases from 20 kg/(m2·s) to 40 kg/(m2·s), the transition vapor quality from stratified flow to stratified-spray flow decreases from 0.7 to 0.3, while the transition vapor quality from stratified-spray flow to spray flow decreases from close to 1 to 0.7; when the proportion of ethane increases from 0% to 50%, the transition vapor quality from stratified flow to stratified-spray flow increases from 0.3~0.45 to 0.43~0.55, while the transition vapor quality from stratified-spray flow to spray flow increases from 0.69~0.85 to 0.83~close to 1. …”
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Fast Green FCF Improves Depiction of Extracellular Matrix in Ex Vivo Fluorescence Confocal Microscopy by Maja Carina Nackenhorst, Adrian Hummel, Maximilian Christian Koeller, Bernd Gollackner, Heinz Regele

“…However, frozen sections are prone to a variety of artefacts and require skilled staff and specialized lab equipment. A potential method for rapid intraoperative tissue evaluation that does not require fixation, freezing, or sectioning of the tissue is ex vivo fluorescence confocal microscopy (FCM). …”
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Deep learning-assisted arrhythmia classification using 2-D ECG spectrograms by Pinjala N Malleswari, Venkata krishna Odugu, T. J. V. Subrahmanyeswara Rao, T. V. N. L. Aswini

“…The proposed pre-trained network combines an Imagenet with huge labeled image datasets and a separate network composed of fully connected layers. This method uses the CWT (Continuous Wavelet Transform) to construct a time-frequency visualization of ECG signals, which are subsequently transformed into RGB images. …”
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Digital platforms for state support of the Olympiad process by Anna V. Diachkova, Dmitry E. Kornev

“…Methodology: systematization and analysis, a comparison method to identify the strengths and weaknesses of digital platforms. …”
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TRENDS IN THE SCIENTIFIC LITERATURE ON THE LEAGILE SUPPLY CHAIN: BIBLIOMETRIC AND CITATION CONTEXT ANALYSES by Nguyen Trong Hien Ton

“…To do so, we use a bibliometric method, combined with citation context analysis, to evaluate data extracted from Scopus peer-reviewed articles published between 1999 and March 2023. …”
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Bright middle cerebellar peduncle sign in multiple system atrophy with predominant cerebellar ataxia is more apparent in double-inversion recovery imaging than in conventional imag... by Wataru Shiraishi, Ayano Matsuyoshi, Yusuke Nakazawa, Yukiko Inamori, Akira Yogi, Tetsuya Hashimoto

“…The DIR procedure can be a more sensitive method for detecting the involvement of MCP lesions in MSA-C.…”
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Nondestructive Identification of Salmon Adulteration with Water Based on Hyperspectral Data by Tao Zhang, Biyao Wang, Pengtao Yan, Kunlun Wang, Xu Zhang, Huihui Wang, Yan Lv

“…For the identification of salmon adulteration with water injection, a nondestructive identification method based on hyperspectral images was proposed. …”
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Indocyanine Green Assisted Removal of Orbital Lacrimal Duct Cysts in Children by Shay Keren, Gad Dotan, Leah Leibovitch, Dinesh Selva, Igal Leibovitch

“…To report on the use of indocyanine green (ICG) during surgical removal of pediatric orbital lacrimal duct cysts. Method. We conducted a retrospective review of our cases of surgical excision of orbital lacrimal duct cysts using intraoperative injection of indocyanine green (ICG), which was used following inadvertent cyst rupture and volume loss. …”
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The Role of Digitalization in Data-Driven Decision Making in Supply Chain Management by I. G. Kamenev, D. A. Porohovnik

“…Using structural-functional analysis and the case study method, the study examines management practices synthesizes a comprehensive approach to exploring the interrelation between technological and managerial innovations during the implementation of digital platforms. …”
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MULTILEVEL MODAL VALUE ANALYSIS FOR INTERPRETING CATEGORICAL K-MEDOIDS CLUSTERS DATA by Rachmad Fitriyanto, Ummi Syafiqoh

“…This study aims to modify the use of K-Medoid and propose a method for interpreting clusters with categorical data. …”
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CONTRAST-ENHANCED COMPUTED TOMOGRAPHY IS THE REQUIRED MINIMUM IN THE DIAGNOSIS OF ABDOMINAL AND RETROPERITONEAL SPACE-OCCUPYING LESIONS by M. V. Stuk, Ya. A. Osokin, E. V. Kondrat’ev, A. V. Varlamov, G. G. Karmazanovskiy

“…Objective: to determine the advantages of contrast-enhanced computed tomography (CT) over contrast-free studies in the differential diagnosis of hepatic, renal, and pancreatic space-occupying lesions. Material and methods. A team of experienced radiologists retrospectively used CT data of patients with different spaceoccupying lesions of the abdomen and retroperitoneal space (liver, kidney, and pancreas). …”
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Mapping peat thickness and groundwater level using a portable electromagnetic instrument in Indragiri Hilir, Riau, Indonesia by Sigit Sutikno, Muhamad Yusa, Andy Hendri, Muhammad Kusairi, Ahmad Muhammad, Nurul Qomar

“…These findings suggest that GWL mapping and peat stratigraphy characterization can be accurately achieved using this method.…”
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Fluorescent EGTA-derived carbon dots for turn on–off–on detection of Fe3+ and ascorbic acid via hydrothermal synthesis and cellular imaging by Kanwal Iqbal, Anam Iqbal, Wenwu Qin, Muhammad Imran, Zeeshan Ajmal, Imran Khan, Guolong Xing

“…Furthermore, the CDs-based Fe3+/AA sensing system proves highly effective for bioimaging applications, allowing for clear visualization of Fe3+ and AA in living cells. Compared to conventional commercial assays, this method is cost-effective, simple, and scalable, offering a powerful tool for next-generation biosensing and bioimaging. …”
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Application of modern computer-aided technologies in the production of individual bone graft: A case report by Mirković Siniša, Budak Igor, Puškar Tatjana, Tadić Ana, Šokac Mario, Santoši Željko, Đurđević-Mirković Tatjana

“…Application of 3D CBCT images, computer-aided systems and software in manufacturing custom bone grafts represents the most recent method of guided bone regeneration. This method substantially reduces time of recovery and carries minimum risk of postoperative complications, yet the results fully satisfy the requirements of both the patient and the therapist.…”
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Effect of Systematic Errors on Building Component Sound Insulation Measurements Using Near-Field Acoustic Holography by Wei Xiong, Wuying Chen, Zhixin Li, Heyu Zhu, Xueqiang Wang

“…After applying the proposed correction method, the NAH measurement results of the domestic microphone array are highly consistent with the weighted sound insulation measured by the standard method, and the measurement difference in the key frequency band is less than 1.0 dB, which significantly improves the reliability and applicability of low-cost equipment in engineering applications. …”
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Hyperspectral Imaging for Enhanced Skin Cancer Classification Using Machine Learning by Teng-Li Lin, Arvind Mukundan, Riya Karmakar, Praveen Avala, Wen-Yen Chang, Hsiang-Chen Wang

“…These conditions are generally not easily detectable due to their comparable clinical presentations. <b>Method:</b> This paper presents a new approach to hyperspectral imaging for enhancing the visualization of skin lesions called the Spectrum-Aided Vision Enhancer (SAVE), which has the ability to convert any RGB image into a narrow-band image (NBI) by combining hyperspectral imaging (HSI) to increase the contrast of the area of the cancerous lesions when compared with the normal tissue, thereby increasing the accuracy of classification. …”
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Intravascular ultrasound-guided reentry wiring with tip-detection technique for chronic total occlusion of lower extremity artery disease by Naoki Hayakawa, Hiromi Miwa, Yasuyuki Tsuchida, Shinya Ichihara, Shunsuke Maruta, Shunichi Kushida

“…The tip-detection (TD) method has been reported as a useful technique in coronary artery CTO interventions, allowing real-time visualization of the GW tip direction. …”
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Laparoscopic Access in Radical Surgical Treatment of Complicated Gastric Cancer: a Single-Center Experience by S. A. Tarasov, P. A. Yartsev, I. I. Kirsanov, M. M. Rogal, S. O. Aksenova

“…These data are an important indicator of the effectiveness of the minimally invasive surgical method of treatment, which indicates greater safety of the laparoscopic method compared to intervention from laparotomy access.…”
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