Psychiatric drugs dispensing trends in the affected population following Brumadinho dam failure by Marcelo Farah Dell'Aringa, Gabriel Elias Correa-Oliveira, Francesco Della Corte, Luca Ragazzoni, Ives Hubloue, Virginia Murray, Thais Piazza, Claudia Garcia Serpa Osorio-de-Castro, Elaine Miranda, Francesco Barone-Adesi

“…This study aims to investigate the impact of this disaster in the dispensing of psychiatric drugs.MethodsWe evaluated monthly aggregated data from 12 months before to 12 months after the event from two data sources, one accounting for psychiatric drugs dispensed by private pharmacies and the other by public health services. …”
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Global trends and interdisciplinary insights in Tai Chi research: a bibliometric analysis (2004–2024) by Bei Li, Xiwei Zhu, Xiwei Zhu, Xiwei Zhu, Haoli Zhang, Su Zhang, Yanwei Li, Shuxi Wu, Shuxi Wu, Shuxi Wu, Jie Han, Jie Han, Jie Han

“…Therefore, a bibliometric analysis of Tai Chi literature can help us better understand the research status and development trends in this field.MethodsThe article and commentary on Tai Chi from 2004 to 2024 were retrieved from the Web of Science Core Collection. …”
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Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation by Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz

“…To evaluate the clinical performance and safety of a hypotonic ophthalmic solution containing sodium hyaluronate 0.2%, xanthan gum 0.2%, and osmoprotectants (glycine and betaine) for treating DED. Methods This multicenter, prospective, observational clinical investigation included 35 subjects treated with one drop of the ophthalmic solution four times daily. …”
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Performance Comparison of 10 State-of-the-Art Machine Learning Algorithms for Outcome Prediction Modeling of Radiation-Induced Toxicity by Ramon M. Salazar, PhD, Saurabh S. Nair, MS, Alexandra O. Leone, MBS, Ting Xu, PhD, Raymond P. Mumme, BS, Jack D. Duryea, BA, Brian De, MD, Kelsey L. Corrigan, MD, Michael K. Rooney, MD, Matthew S. Ning, MD, Prajnan Das, MD, Emma B. Holliday, MD, Zhongxing Liao, MD, Laurence E. Court, PhD, Joshua S. Niedzielski, PhD

“…Figures were generated to visually compare the performance of the algorithms. …”
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Prediction of EGFR mutations in non-small cell lung cancer: a nomogram based on 18F-FDG PET and thin-section CT radiomics with machine learning by Jianbo Li, Qin Shi, Yi Yang, Jikui Xie, Qiang Xie, Ming Ni, Xuemei Wang, Xuemei Wang

“…BackgroundThis study aimed to develop and validate radiomics-based nomograms for the identification of EGFR mutations in non-small cell lung cancer (NSCLC).MethodsA retrospective analysis was performed on 313 NSCLC patients, who were randomly divided into training (n = 250) and validation (n = 63) groups. …”
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The interdependence of mid-trimester blood pressure and glucose levels in shaping fetal growth and neonatal outcomes: implications for risk–benefit assessment and co-management by Lijuan Lv, Jingbo Yang, Linjie Li, Chuanyi Huang, Huihua Shi, Yiwen Fang, Lushu Zuo, Ting Liu, Hongli Duan, Jiying Wen, Qing Yang, Amanda Henry, Cha Han, Aihua Yin, Xin Zhou

“…How the interdependence of blood pressure (BP) and glucose levels quantitatively influences risk patterns for abnormal fetal growth and neonatal complications remains unexplored. Methods Maternal BP and fasting plasma glucose (FPG) levels were measured between 20 and 28 weeks of gestation in a cohort including 56,881 singleton pregnancies. …”
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Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema: a prospe... by Yao-Yao Sun, Jie Meng, Shan-Shan Li, Qin Xiao, Tian-Zi Zhang, Heng Miao, Ming-Wei Zhao, Hui-Jun Qi

“…AIM: To evaluate the efficacy and safety of concurrent intravitreal ranibizumab (IVR) and extended-release dexamethasone injections (Dex-I) in naïve and refractory patients with retinal vein occlusion macular edema (RVO-ME). METHODS: This was a prospective, interventional, and open-label clinical trial. …”
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Modified double-row suture bridge technique for anterior colliculus fractures combined with deltoid ligament injury: a retrospective study by Jianlong Ni, Zhihao Chen, Wang Wei, Ruiying Li, Dazhi Wang, Dongjian Wang, Zenan Tian, Zhikun Jia, Qichun Song, Meng Feng, Zhibin Shi

“…The purpose of the present study was to describe the application of a modified double-row suture bridge technique and evaluate its early clinical outcomes in the management of anterior colliculus fracture combined with deltoid ligament injury. Methods From 2020 to 2022, 12 patients with anterior colliculus fracture combined with deltoid ligament injury were treated using a modified double-row suture bridge technique. …”
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Prevalence and risk factors for antenatal anxiety in the first trimester among Chinese pregnant women by Li Zhang, Yan Zhang, Jin Liu, Yan Yu, Junzhe Cheng, Yumeng Ju, Mi Wang, Bangshan Liu, Shuyin Xu, Mengqi Xu, Yilin Peng, Jintao Xiong, Xuemei Qin, Zhuo Peng, Weiguo Mao, Meiqun Xiao

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Gene-environment interactions and colorectal cancer risk: A case-control study on xenobiotic metabolizing enzyme polymorphisms in the Jammu& Kashmir, India population by Gowhar Rashid, Gulzar A. Bhat, Tahseen Bilal Rather, Kulsum Akhter, Ishrat Parveiz, Irfan Maqbool, Syed Nisar Ahmad, Malik Tariq Rasool, Farooq Ahmad Jan, Syed Mudassar

“…Blood samples were collected for DNA extraction, followed by genotyping of xenobiotic-metabolizing enzyme (XME) genes, including CYP2A13, CYP2A6, and GSTs using standard PCR-RFLP and multiplex PCR methods. Statistical analyses were performed using STATA software to assess the association between gene polymorphisms and CRC risk. …”
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Disease phenotypic and outcome of very-early onset inflammatory bowel disease in Asian children: an understudied population by Way-Seah Lee, Way-Seah Lee, Kee-Seang Chew, James-Guoxian Huang, James-Guoxian Huang, Pornthep Tanpowpong, Karen S. C. Mercado, Almida Reodica, Veena Logarajah, K. L. W. Hathagoda, Shaman Rajindrajith, Yoko Kin-Yoke Wong, Suporn Treepongkaruna, Marion Margaret Aw, Marion Margaret Aw

“…We studied disease phenotype, clinical characteristics, management and outcome of VEO-IBD in South and Southeast Asian children.Materials and methodsWe extracted data from a multicentre Asian pediatric (onset <18 years) IBD registry. …”
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Comparative Efficacy of Subcutaneous Versus Intravenous Interleukin 12/23 Inhibitors for the Remission of Moderate to Severe Crohn’s Disease: A Systematic Review and Meta-Analysis... by Nouran Alwisi, Rana Ismail, Hissa Al-Kuwari, Khalifa H. Al-Ansari, Mohammed A. Al-Matwi, Noor A. Aweer, Wejdan N. Al-Marri, Yousif Al-Kubaisi, Muneera Al-Mohannadi, Shahd Hamran, Suhail A. R. Doi, Habib H. Farooqui, Tawanda Chivese

“…This research synthesized evidence on the efficacy and safety of subcutaneous compared to intravenous administration of interleukin 12/23 inhibitors for moderate to severe CD. <b>Methods</b>: In this systematic review and meta-analysis, we searched Cochrane, PubMed, SCOPUS, CINHAL, and preprint archives for randomized controlled trials (RCTs) that compared the efficacy and safety of subcutaneous to intravenous interleukin 12/23 inhibitors for the remission of CD. …”
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Oral health literacy and oral health status of a german adult population with migration background – findings from the MuMi Study by Berit Lieske, Christopher Kofahl, Katrin Borof, Kristin Spinler, Anna Poth, Demet Dingoyan, Thomas Beikler, Guido Heydecke, Ghazal Aarabi

“…This article presents results on oral health and oral health literacy from the baseline data of the cluster-randomized controlled MuMi study (Promotion of oral health literacy and oral health of persons with migration background). Methods: Comparative cross-sectional data on oral health and oral health literacy of patients with and without migration background were examined in 40 dental practices in Hamburg, Germany. …”
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Comparison of myopia-related behaviors among Chinese school-aged children and associations with parental awareness of myopia control: a population-based, cross-sectional study by Chaoying Ye, Chaoying Ye, Chaoying Ye, Yujie Wang, Yujia Liu, Yujia Liu, Yujia Liu, Xingxue Zhu, Xingxue Zhu, Xingxue Zhu, Jianmin Shang, Jianmin Shang, Jianmin Shang, Xiaomei Qu, Xiaomei Qu, Xiaomei Qu

“…Therefore, we assessed the myopia-related behaviors and parental awareness of school-aged children in different city tiers of China with different refractive statuses.MethodsA population-based, cross-sectional study was conducted on Chinese children from 110 cities aged 7–15 years. …”
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Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort by Valériane Leroy, Anandi Sheth, Julie Jesson, Jean Jacques Koffi, Antoine Jaquet, François Dabis, Didier Koumavi Ekouevi, Karen Malateste, Olivia Keiser, Lehila Bagnan, Simon Boni, Madeleine Amorissani Folquet, Mariam Sylla, Olivier Marcy, Raoul Moh, Gildas Boris Hedible, Sophie Desmonde, Joycelyn Dame, Agatha David, Madeleine Amorissani-Folquet, Sylvie N'Gbeche, Elom Takassi, François Tanoh Eboua, Kouadio Kouakou, Lehila Bagnan Tossa, Caroline Yonaba, Jocelyn Dame, Sylvie Marie N’Gbeche, Fatoumata Dicko Traore, Oliver Ezchechi, Rosemary Audu, Charlotte Bernard, Caroline Couturier, Marie Kerbie Plaisy, Elodie Rabourdin, Thierry Tiendrebeogo, Désiré Dahourou, Emile Sodinyessi, Jean-Claude Azani, Kadidja Diarra, Maika Bengali, Abdoulaye Cissé, Guy Gnepa, Eric Komena, Séverin Lenaud, Eulalie Kangah, Igho Ofotokun, Cecile Delille Lahiri, Noëlle Benzekri, Geoffrey Gottlieb

“…Introduction We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa.Methods We included all patients aged 0–24 years on ART from nine clinics in Côte d’Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. …”
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Hand Grip Strength Cut‐Off Points as a Discriminator of Sarcopenia and Sarcopenic Obesity: Results from the ELSA‐Brasil Cohort by Clarice Alves Santos, Helena Fraga Maia, Francisco José Gondim Pitanga, Maria da Conceição Chagas deAlmeida, Maria de Jesus Mendes daFonseca, Estela Mota Leão deAquino, Letícia de Oliveira Cardoso, Rosane Harter Griep, Sandhi Maria Barreto, Claudia Kimie Suemoto, Paulo Lotufo, Isabela Bensenor, Sheila Maria Alvim deMatos

“…Objective The study aimed to evaluate the performance of HGS as discriminator of sarcopenia and sarcopenic obesity, compared to urinary biomarkers of creatinine and potassium in 24 h for Brazilian adults. Methods Cross‐sectional study. Women (n = 5431) and men (n = 6351) aged 38–79 years who participated in the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) at second follow‐up of the cohort (2012–2014). …”
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[18F]FMISO PET in metastatic neuroendocrine tumours: a pilot study by David Chan, Alice Conner, Nick Pavlakis, Elizabeth Bailey, Alireza Aslani, Kathy Willowson, Connie Diakos, Elizabeth Bernard, Stephen Clarke, Alexander Engel, Paul Roach, Dale Bailey

“…The presence of hypoxia may have prognostic and therapeutic implications, and was evaluated in these lesions using the PET hypoxia imaging biomarker [18F]FMISO. Methods: Prospective pilot study in patients with metastatic NENs with at least one DONUT lesion (central [68Ga]DOTATATE non-avidity). [18F]FDG and [18F]FMISO scans were acquired within 60 days of the [68Ga]DOTATATE PET/CT. [18F]FMISO scans were acquired as a dynamic scan over 20 mins from injection with a delayed image at 2 hours. …”
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Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population by Ashok Kumar Yadav, Jaskiran Kaur, Prabhjot Kaur, Kajal Kamboj, Yoshinari Yasuda, Masaru Horio, Arnab Pal, Nusrat Shafiq, Nancy Sahni, Harbir Singh Kohli, Seiichi Matsuo, Vivek Kumar, Vivekanand Jha

“…We investigated the performance of race-free eGFR equations in the Indian population. Methods: Patients with chronic kidney disease (CKD) and potential kidney donors attending the outpatient clinic at the Postgraduate Institute of Medical Education and Research Chandigarh, India, were screened for enrolment. …”
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Combination of Essential Oils and Extracts Enriched with Tocopherols in Diet of Holstein Steers and Its Effect on Ruminal Fermentation, Antioxidant and Anti-Inflammatory Response,... by João Gustavo Weschenfelder Wandscheer, Natalia Turcatto, Guilherme Luiz Deolindo, Mateus Henrique Signor, Alexandro Fritzen, Marcelo Vedovatto, Camila Ten Kathen Jung, Gilberto Vilmar Kozloski, Ana Carolina Hadlich Xavier, Roger Wagner, Bianca Fagan Bissacotti, Priscila Marquezan Copetti, Aleksandro Schafer da Silva

“…Background: This experiment evaluated whether the combination of essential oils (thyme, rosemary, orange) with extracts of <i>Cinnamomum</i> and <i>Quillaja saponaria</i> (enriched with tocopherols) in steers’ diet has positive effects on the health, digestibility, growth, oxidative stress, and fatty acid profile of meat. Methods: The experiment included 24 Holstein steers, divided into two groups, randomly divided (treated = phytogenic mixture (n = 12); control = monensin (n = 12)), undergoing a growth phase of 120 days and 90 days of finishing in individual pens, with a monthly collection of blood, rumen fluid, feces, and feed. …”
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Normal tissue complication probability modeling for late rectal bleeding after conventional or hypofractionated radiotherapy for prostate cancer by Christian A.M. Jongen, Ben J.M. Heijmen, Wilco Schillemans, Andras Zolnay, Marnix G. Witte, Floris J. Pos, Ben Vanneste, Ludwig J. Dubois, David van Klaveren, Luca Incrocci, Wilma D. Heemsbergen

“…Purpose: To develop a single NTCP model for grade ≥ 2 late rectal bleeding (G2 LRB) after conventional or hypofractionated radiotherapy for prostate cancer. Methods and Materials: The development dataset consisted of prostate cancer patients (n = 656) previously randomized to conventional (39 x 2 Gy) or hypofractionated (19 x 3.4 Gy) external beam radiotherapy with N = 89 G2 LRB cases. …”
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