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30841
Effectiveness of AI-Driven Conversational Agents in Improving Mental Health Among Young People: Systematic Review and Meta-Analysis
Published 2025-05-01“…ObjectiveThis study aims to examine the effectiveness of AI-driven CAs for mental health among young people, and explore the potential moderators of efficacy. MethodsA total of 5 main databases (PubMed, PsycINFO, Embase, Cochrane Library, and Web of Science) were searched systematically dated from the establishment of the database to August 6, 2024. …”
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30842
Development of a Serious Game to Simulate Neonatal Intensive Care Unit Experiences: Collaborative Quasi-Experimental Study
Published 2025-06-01“…Structured as a 6-chapter visual novel, the game follows a high school student observing the NICU during a hospital internship. …”
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30843
Enhanced Teleoperation of Robotic Arms Through Master-Slave Configuration With Multithreading
Published 2025-01-01“…Low-pass filtering techniques were applied to suppress signal noise and improve trajectory smoothness, while multithreading methods were used to separate sensor polling and data transmission processes. …”
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30844
Reliability and Validity Study of the <italic>International Classification of Functioning</italic>,<italic>Disability and Health Rehabilitation Set</italic> in Rehabilitation of Kn...
Published 2024-12-01“…ObjectiveTo explore the reliability and validity of the <italic>International Classification of Functioning, Disability and Health Rehabilitation Set</italic> (ICF-RS) in assessing the body function, activities and social participation of patients with knee osteoarthritis (KOA).MethodsA total of 60 KOA patients in the Outpatient Department of Orthopedic Rehabilitation in the Fifth Hospital of Xiamen and the Xiangyang Central Hospital from October to December 2022 were recruited. …”
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30845
A 360° Approach to Personalize Lifestyle Treatment in Primary Care for People With Type 2 Diabetes: Feasibility Study
Published 2024-12-01“…ObjectiveThis work examines the acceptability, implementation, and potential effects of the 360° diagnostic tool and subsequent tailored treatment (360° approach) in a 6-month intervention and feasibility study conducted in standard primary health care settings in the Netherlands. MethodsA single-group design with baseline, 3-month, and 6-month follow-ups was used. …”
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30846
The clinical efficacy of hybrid surgery based on the Waveflex semi-rigid dynamic internal fixation system for the treatment of lumbar degenerative diseases: over three-year follow-...
Published 2025-05-01“…Abstract Objective To investigate the efficacy and safety of hybrid surgery based on the Waveflex internal fixation system for the treatment of lumbar degenerative disease. Methods A retrospective analysis was conducted on 31 consecutive patients who underwent hybrid surgery (fusion combined with non-fusion surgery) using the Waveflex internal fixation system for lumbar degenerative diseases between December 2019 and May 2021. …”
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30847
Defining the relationship between clinician-rated ECOG performance status and patient-reported health-related quality of life scores in men with metastatic hormone-naïve prostate c...
Published 2024-12-01“…The aim of this study is to define the relationship between clinician-rated ECOG-PS and the patient-reported HRQoL in men with metastatic hormone-naïve prostate cancer (mPCa). Methods An analytical cross-sectional study recruiting patients presenting with mPCa in Enugu, southeast Nigeria. …”
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30848
Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration
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30849
Early peripapillary neurovascular injury and its relevant systemic factors in type 2 diabetic patients without retinopathy: An OCTA based study
Published 2025-08-01“…Purpose: To determine the ability of peripapillary neurovascular units (NVU) to detect early changes in the retinal microvasculature and microstructure, and to explore systemic factors linked to the peripapillary NVU injury in type 2 diabetic patients without clinically detectable retinopathy (NDR). Methods: Fifty-two NDR patients (mean age 51.08 ± 9.60 years; 24 females; diabetes duration 8.74 ± 6.71 years) and 42 age- and sex-matched healthy controls (mean age 50.24 ± 7.97 years; 20 females) were recruited for this prospective, cross-sectional study. …”
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30850
CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target
Published 2024-12-01“…In this work, we first explain the great potential of CYFIP2 malignant progression from a broader perspective (pan-cancer) and confirm its oncogenic value in pancreatic cancer. Methods The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, CELL and GEO databases were utilized to explore the distribution of the CYFIP2 gene in human cancers. …”
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30851
MYOCARDIAL PERFUSION AND NEUROTROPIC SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY FEATURES IN PATIENTS WITH PRIMARY PULMONARY HYPERTENSION
Published 2018-12-01“…To compare cardiac 123I-MIBG and 99m Tc-MIBI single-photon emission computed tomography (SPECT) data in patients with primary pulmonary hypertension (PPH).Material and methods. The study included 22 patients with confirmed diagnosis of PPH, with clinical status assessment, Holter ECG monitoring and rest cardiac ultrasound (US) data. …”
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30852
Myofascial trigger points therapy increases neck mobility and reduces headache pain in migraine patients – pilot study
Published 2025-02-01“…Design A case series employing a repeated-measures design; pilot study. Methods Fifty-three adult female migraine patients were classified into three groups: episodic migraine without aura (MO, n = 31), episodic migraine with aura (MA, n = 15), and chronic migraine (CM, n = 7). …”
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30853
Dark Adaptometry Kinetics Differentiates Age-Related Macular Degeneration from Central Serous Chorioretinopathy
Published 2025-11-01“…Participants: Consecutive patients with a clinical diagnosis of AMD or CSCR who were ≥50 years of age. Methods: The study included patients who had completed a DA study in ≥1 eye measured at 5° superior to the fovea on the retina. …”
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30854
Quercetin inhibits ferroptosis to alleviate intestinal ischemia-reperfusion injury
Published 2025-06-01“…Objective To investigate the role of quercetin (QUE) in ferroptosis during intestinal ischemia-reperfusion (IR) injury and elucidate its underlying mechanisms. Methods ① Potential target genes of QUE were predicted using the TCMSP, PharmMapper, and SwissTargetPredictive databases. …”
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30855
Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma
Published 2015-01-01“…Patient's symptoms, bests corrected visual acuity and IOP were recorded 7 days, and 1, 3 and 6 months after the DCPC treatment. …”
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30856
Identification and validation of NEIL2 as a prognostic biomarker and potential therapeutic target in cervical cancer
Published 2025-07-01“…Therefore, the aim of this study was to explore the potential mechanisms of NEIL2 as a novel prognostic biomarker for CC patients. Methods Firstly, the Cancer Genome Atlas (TCGA)—Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (CESC) dataset was acquired from the University of California Santa Cruz Xena database. …”
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30857
End-stage Ankle Arthritis: Variations in the Current State of Practice of Asia-Pacific Foot and Ankle Surgeons
Published 2023-07-01“…Background: This study is aimed to assess differences in the pattern of practice and choice of management of end-stage ankle arthritis among established Asia-Pacific foot and ankle surgeons. Materials and methods: A survey was presented to fellowship trained foot and ankle surgeons registered with their respective national orthopedic professional societies practicing in the Asia-Pacific region. …”
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30858
Chronic Isolated Fracture of the Metatarsal Head in Lesser Toes Treated with Open Reduction and Internal Fixation
Published 2024-12-01“…This study aims to report the clinical and imaging characteristics, as well as treatment results, of these fractures. Methods: A retrospective consecutive case-series study was performed on 5 patients with symptomatic chronic isolated shear fracture of a metatarsal head in the lesser toes from January 2018 to April 2021. …”
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30859
Impact of Sagittal Spinal Balance on Functional Recovery After PLIF of L5‐S1 Isthmic Spondylolisthesis With Lumbar Spinal Stenosis
Published 2025-06-01“…This study analyzes the influence of residual sagittal imbalanceon health‐related quality of life (HRQOL) after PLIF for L5‐S1 IS with LSS, aiming to optimize surgical correction and prognostic accuracy. Methods This study analyzed 103 consecutive patients with L5‐S1 IS and LSS undergoing PLIF from 2020 to 2022, followed at 3 days, 3 months, and ≥ 1 year postoperatively, using SPSS 26.0 for statistical analysis. …”
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30860
Human congenital cataract mutation in MYH9 alters F-actin organization and cell functions
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