Analysis of clinical knowledge, absenteeism and availability of resources for maternal and child health: a cross-sectional quality of care study in 10 African countries by Laura Di Giorgio, David K Evans, Magnus Lindelow, Son Nam Nguyen, Jakob Svensson, Waly Wane, Anna Welander Tärneberg

“…Objective Assess the quality of healthcare across African countries based on health providers’ clinical knowledge, their clinic attendance and drug availability, with a focus on seven conditions accounting for a large share of child and maternal mortality in sub-Saharan Africa: malaria, tuberculosis, diarrhoea, pneumonia, diabetes, neonatal asphyxia and postpartum haemorrhage.Methods With nationally representative, cross-sectional data from ten countries in sub-Saharan Africa, collected using clinical vignettes (to assess provider knowledge), unannounced visits (to assess provider absenteeism) and visual inspections of facilities (to assess availability of drugs and equipment), we assess whether health providers are available and have sufficient knowledge and means to diagnose and treat patients suffering from common conditions amenable to primary healthcare. …”
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Effectiveness of telerehabilitation in non-operatively managed shoulder conditions: a systematic review and meta-analysis by Ting-wan Lin, Yang Yang, Hai-yan Hong, Xiao-bo Zhou, Tao-Hsin Tung, Bin-bin Zheng, Jian-min Zhang

“…However, its overall efficacy remains uncertain due to inconsistent findings in prior studies. Methods This systematic review and meta-analysis assessed the effectiveness of telerehabilitation for non-operatively managed shoulder conditions, concentrating on randomized controlled trials (RCTs). …”
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Resting-state functional magnetic resonance imaging findings in patients with acoustic neuroma and tinnitus by ZHAN Xiaolin, REN Yi, LI Yongpeng, HUANG Qiao, YIN Shihua

“…Objective To investigate the neural network mechanism of tinnitus in patients with acoustic neuroma by observing the imaging findings of resting-state functional magnetic resonance imaging (rs-fMRI). Methods A total of 18 patients with acoustic neuroma who were hospitalized in the Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Guangxi Medical University from November 2022 to December 2023 for concurrent surgical treatment were divided into a tinnitus group (group A) and a non-tinnitus group (group B) based on the presence or absence of tinnitus. …”
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U-shaped association between serum chloride and hypertension risk with nadir around 103 mmol/L: insights from regression and interpretable machine learning (XGBoost/SHAP) using NHA... by Shancheng He, Xuemei Zhong, Guangming Chen, Long Li

“…This research attempted to explicate the link between serum levels of chloride and the risk of hypertension occurrence, as well as to identify the threshold level at which the risk undergoes changes across the general population and various demographic segments.MethodsEmploying materials from the to 2017–2018 National Health and Nutrition Examination Survey (NHANES; n = 4,591), we employed multivariate regression analysis to gauge the connection between adult serum chloride concentrations and the risk of hypertension occurring. …”
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Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo by E. V. Zaikina, I. A. Alliluev, Yu. N. Lazutin, Yu. V. Przhedetskiy, Yu. S. Shatova, M. A. Engibaryan, E. F. Komarova, D. A. Kharagezov, A. V. Galina, A. A. Kiblitskaya, M. V. Mindar, L. Z. Kurbanova

“…Evaluation of the antioxidant status and DNA damage in tissues of subcutaneous xenografts of non-small cell lung cancer and in peritumoral tissues created using the A549 and H1299 cell cultures.Materials and methods. The study included 35 intact male Balb/c Nude immunodeficient mice. …”
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Relationship between latent left ventricular contractile dysfunction and signs of immune inflammation in patients with COVID-19 pneumonia by N. E. Shirokov, E. I. Yaroslavskaya, D. V. Krinochkin, N. A. Musikhina, T. I. Petelina, N. A. Osokina

“…To investigate the relationship between echocardiographic parameters and laboratory immune inflammation signs in patients after coronavirus disease 2019 (COVID-19) pneumonia depending on the left ventricular (LV) involvement according to speckle tracking echocardiography (STE).Material and methods. The study included 216 patients (men, 51,1%, mean age, 50,1±11,1 years). …”
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A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay by Luanpitpong S, Janan M, Poohadsuan J, Rodboon N, Samart P, Rungarunlert S, Issaragrisil S

“…Components in BM niche contribute to the immunosuppressive tumor microenvironment (TME), but three-dimensional (3D) MM models that recreate the complex TME and enable high-throughput cytotoxicity assay of chimeric antigen receptor (CAR)-engineered immune cells are still lacking.Methods: Stable, luciferase (Luc)-labeled target MM cells were generated using Luc/RFP dual reporter system to track MM growth. 3D spheroids were formed in a 96-well plate in the presence or absence of cancer-associated fibroblast (CAF)-like stromal cells activated by MM-derived conditioned medium and the cytotoxicity of CAR-immune cells, which were represented by third-generation anti-CD138 CAR-NK-92 cells, was evaluated by luciferase assay using a multimode microplate reader. …”
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Isolated Transpupillary Photodynamic Therapy in Local Treatment of Choroidal Melanoma by I. E. Panova, E. V. Boiko, E. V. Samkovich, V. G. Gvazav

“…Objective: To evaluate the long-term results of local application of transpupillary photodynamic therapy (PDT) with chlorine photosensitizer in isolated organ-preserving treatment of uveal melanoma (UM) and to determine predictors of its effectiveness.Patients and methods. Retrospective analysis of transpupillary PDT efficacy in 38 patients (38 eyes) diagnosed with choroidal melanoma (CM) treated between 2016 and 2024. …”
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Changes in the Relationship Between Gray Matter, Functional Parameters, and Quality of Life in Patients with a Post-Stroke Spastic Upper Limb After Single-Event Multilevel Surgery:... by Patricia Hurtado-Olmo, Pedro Hernández-Cortés, Ángela González-Santos, Lourdes Zuñiga-Gómez, Laura Del Olmo-Iruela, Andrés Catena

“…<b>Objective</b>: To compare structural MRI-evaluated gray matter volume changes in patients with post-stroke upper limb spasticity for >1 year between those undergoing surgery and those treated with botulinum toxin A (BoNT-A) and to relate these findings to upper limb function and quality of life outcomes. <b>Materials and Methods</b>: <i>Design.</i> A two-arm controlled and randomized clinical trial in patients with post-stroke upper limb spasticity. …”
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USE OF METHOTREXATE IN PATIENTS WITH CALCIUM PYROPHOSPHATE CRYSTAL DEPOSITION DISEASE by M. S. Eliseev, S. A. Vladimirov, E. L. Nasonov

“…Objective: to compare the efficacy of methotrexate (MTX) and colchicine in patients with chronic arthritis in calcium pyrophosphate crystal deposition disease (CPPDD).Subjects and methods. Data from a controlled prospective cross-sectional study of 10 patients (8 women and 2 men) with chronic arthritis in CPPDD are presented. …”
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Effect of Ropivacaine Epidural Block Combined with General Anesthesia on the Expression of Oxidative Stress and Immune Indexes in Elderly Patients with Ovarian Cancer Cell Cytoredu... by Jianmei Yang, Xiaoyan Xu, Lijun Guo, Yuxuan Yan, Huiling Liu

“…This study aims to evaluate the impact of REB combined with GA on oxidative stress and immune parameters in elderly patients undergoing cytoreductive surgery for OC. Methods: Out of 124 eligible patients undergone OC cytoreductive surgery at Lanzhou First People’s Hospital (June 2022–December 2023), 79 patients received intravenous general anesthesia and 45 patients received ropivacaine epidural block combined with general anesthesia. …”
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Impact of Midfoot Charcot Arthropathy (Brodsky Type 1) on Patient Reported Outcome Scores by Seth J. Tysor BS, Christopher E. Gross MD, Daniel J. Scott MBA, MD, Joshua L. Morningstar BS, Joseph Cutrone BS, Michael Otten MD

“…We will compare these values with PROMs from conditions like ESRD, knee and hip arthritis, highlighting Charcot arthropathy's comparable debilitation. Methods: A retrospective chart review identified 67 patients with Brodsky Type 1 Charcot arthropathy by one of two fellowship-trained foot and ankle surgeons at a single academic medical center between years 2015 and 2023. …”
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Thoracic paravertebral block versus local infiltration anesthesia for percutaneous kyphoplasty to treat osteoporotic vertebral compression fractures combined with intercostal neura... by Yimin Li, Haijie Xia, Shucheng Chen, Yunfan Qian, Guangjie Shen, Xiqiang Zhong, Zhiqiang Jia, Chengxuan Tang, Shaoqi He

“…This study aims to compare the efficacy and safety of thoracic paravertebral nerve block (TPVB) and local infiltration (LI) anesthesia for PKP to treat thoracic OVCFs combined with IN. Methods Patients with OVCFs combined with IN scheduled to undergo PKP between January 2021 and June 2022 were randomized into the following groups: TPVB and LI. …”
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Traditional Chinese medicine manual therapy for adolescent idiopathic scoliosis: a case report by Bowen Zhu, Miaoxiu Li, Jun Ren, Tianxiang He, Xin Zhou, Shoujian Wang, Lingjun Kong, Min Fang, Min Fang

“…ObjectivesThis case demonstrates the efficacy and safety of Traditional Chinese Medicine manual therapy (TCMMT) for the treatment of mild to moderate AIS.MethodsAn 10-year-old girl who suffered from low back pain (LBP) with marked shoulder inequality and razorback postural abnormalities, with a clinical diagnosis of idiopathic scoliosis, and the Cobb angle of 20° and angle of trunk rotation (ATR) of the thoracic vertebral segment at 7°, and ATR of the lumbar vertebral segment at 8°, was treated with TCMMT. …”
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Does the blood glucose control have an effect on the success of the painful diabetic neuropathy treatment? by Jovanikić Olivera, Anđelić Gordana, Lepić Milan, Mirković Dušica, Jovanović Bojan, Lepić Toplica, Dragović Tamara

“…We monitored the impact of glucoregulation on the efficacy of painful diabetic neuropathy (PDN) treatment, when all pharmaceutical treatment options were exhausted. Methods. Patients (n = 53, both gender, average age 68.3 ± 12.6) with PDN resistant to the pharmacotherapy were treated with the ultrasound- guided local anesthetic (0.5% procaine hydrochloride, 1% lidocaine, 0.25% levobupivacaine) blocks. …”
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Two-Port Needle-Assisted Pediatric Laparoscopic Herniotomy Using Tuohy Needle: Clinical Experience and Outcomes by Imran Abbas, Rida Fatima, Muhammad Aslam Javed, Muhammad Hassan, Mahmood Farooqi, Muhammad Mohsin Gillani

“…Tuohy Needle-assisted Laparoscopic hernia repair has several advantages over the open repair technique, including shorter recovery times, the ability to evaluate and repair contralateral defects, reduced postoperative complications, and improved outcomes. Methods: This descriptive case series study was conducted in the Department of General Surgery at Sharif Medical City Hospital, Lahore, over a period of six months. …”
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Rhinoplasty without nasal packing and splinting by Vulović Dejan, Kozarski Jevta, Radivojčević Uroš, Stepić Nenad, Milićević Saša, Petrović Nenad T.

“…In assessing postoparative pain, the visual analogue scale (VAS) in a range of 1 to 5 was used. …”
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Examining differences in exposure to digital marketing of unhealthy foods reported by Canadian children and adolescents in two policy environments by Laura Vergeer, Carolina Soto, Mariangela Bagnato, Elise Pauzé, Ashley Amson, Tim Ramsay, Dana Lee Olstad, Vivian Welch, Monique Potvin Kent

“…This study examined differences in self-reported exposure to digital food marketing between children and adolescents in different policy environments: Ontario (where food marketing is self-regulated) and Quebec (where advertising is government regulated). Methods An observational cross-sectional online survey was conducted in April 2023 among children (aged 10–12 years) and adolescents (13–17 years) from Ontario and Quebec, recruited by Leger Marketing. …”
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Çocuklarda Dental Anksiyete: Başarılı Dental Tedavinin Önündeki Engel by Aysun Avşar, Büşra Mutlu

“…In order to progress and complete the steps of dental treatment, anxiety can be managed non-pharmacologically with pharmacological methods such as sedation and general anesthesia, aromatherapy, music therapy, visual and auditory distraction and hypnosis by watching videos during treatment. …”
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Efficacy of Different Doses of Intra‐Articular Tranexamic Acid for Reducing Blood Loss and Lower Limb Swelling After Total Knee Arthroplasty: A Prospective, Randomized, Controlled... by Shuwei Ye, Yue Luo, Qianhao Li, Lijun Cai, Pengde Kang

“…The aim of this trial was to investigate whether different doses of intra‐articular tranexamic acid (TXA) can reduce blood loss and postoperative lower limb swelling. Methods In a prospective, randomized‐controlled trial, a total of 225 patients were randomly assigned to three groups from September 2020 through January 2021: intra‐articular injections of 3 g, 1 g of TXA, or placebo (saline solution). …”
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