The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan by Sube KL, Lako JDW, Tongun JB, Gerber T, Mamur JP, Hamid Moto SJ, Jada SRL, Siewe Fodjo JN, Hopkins AD, Mackenzie CD, Colebunders R

“…The objective of this study was to determine the causes of eye disease and blindness in Raga County as well as to assess the relationship of eye diseases with other prevalent conditions like onchocerciasis and epilepsy.Methods: We reviewed unpublished pre-community directed treatment with ivermectin (CDTI) data about eye disease and onchocerciasis in Western Bahr El Ghazal including Raga. …”
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Comparative Efficacy of Carbamazepine Therapy With and Without Transcutaneous Electrical Nerve Stimulation Therapy in Trigeminal Neuralgia Patients: A Randomised Controlled Trial P... by Rutumbara Gajanan Dhone, Vidya Krunshnarao Lohe

“…Aim: To evaluate and compare the efficacy of CBZ therapy with and without TENS therapy for the management of TN. Materials and Methods: A Randomised Controlled Trial (RCT) will be conducted in the Outpatient Department (OPD) of Oral Medicine and Radiology at Sharad Pawar Dental College and Hospital, Wardha, Maharashatra, India between July 2024 and May 2026. …”
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Kinematic and kinetic features of an unaffected limb during walking in children with spastic hemiplegia by Ulvi F. Mamedov, Tamara I. Dolganova, Lidiia V. Smolkova, Anatoly O. Trofimov, Orkhan I. Gatamov, Dmitry A. Popkov

“…Objective To determine the features of compensatory and adaptive behavior of the limb not involved in the pathogenesis in children with hemiplegia during walking and their dependence on age and previous surgical interventions on the triceps surae. Materials and methods Locomotor characteristics of 78 children under 16 years of age with spastic hemiplegia and motor disorders corresponding to levels I–II GMFCS (Gross Motor Function Classification System) were compared with 77 healthy peers. …”

Short-term outcomes of faricimab and aflibercept 8 mg in diabetic macular edema by Carlo Maccauro, Yanny Jimenez Perez, Piergiorgio Neri, Ibraheem El Ghrably, Haytham I Salti, Francesco Pichi

“…Patients were selected based on clinical and imaging criteria confirming the presence of center-involving DME requiring anti-vascular endothelial growth factor (VEGF) therapy. Methods: Patients received loading doses of either four monthly faricimab injections or three aflibercept 8 mg injections and were followed for a total of approximately 6 to 9 months, including both loading and PRN phases. …”
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Chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels: a network analysis on 2018 CHARLS data by Qiaofeng LI, Yilong YAN, Yuehan HE, Yongtai LI, Guowu DING

“…ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment. MethodsData from 14 222 middle-aged and elderly individuals aged ≥ 45 years old were collected from the 2018 China Health and Retirement Longitudinal Study (CHARLS). …”
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Dry Eye Epidemiology in Patients before Refractive Operations by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Y. A. Kalantaevskaya, R. A. Ismaylova, E. M. Ehieva, M. V. Grishenko, I. V. Gorbunova, O. F. Ozhug, O. A. Klokova

“…To evaluate the prevalence, clinical severity, clinical and pathogenetic variants and etiology of dry eye (DE) in patientsbefore refractive surgery. Methods. OSDI testing, lipid interferential test, TBUT, Shirmer-1, -2 tests, compression Norn test in Korbmodification, calculation of xerosis index by Bijsterveld, tear meniscus index evaluation, LIPCOF test, evaluation of epitheliopaty and microerosion by Tseng and lid viper epitheliopaty were performed in 600 myopia (with or without astigmatism) patients (234 men, 366 women; 30.1 ± 6.26 years old) before refractive surgery. …”
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Comparative study on the quality of life and clinical efficacy of orthokeratology lens, defocus spectacle lens and single vision spectacles in myopic children and adolescents in Ch... by Sile Yu, Wei He, Yang Li, Tingting Zhao, Li Lin, Xiaonan Liu, Jiayan Chen, Guanghao Qin, Xingru He, Ruyi Li, Yibing Zhou

“…Purpose To evaluate and compare the vision-related quality of life and efficacy between myopic children and adolescents wearing orthokeratology (OK) lens, defocus spectacle (DS) lens and single vision spectacle (SVS).Methods This ambispective cohort study involved 93 participants who had worn optical correction lenses (31 OK lens, 31 DS lens and 31 SVS) for 1 year. …”
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Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downre... by Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A.O.A. Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono

“…Aim: This study analyzes the therapeutic efficiency of conditioned medium or secretome produced from BUMSC-CM in treating neurodegeneration in animal models of AD. Methods: Five groups consisting of twenty-five male rats were assigned: untreated (Group A, n=5), positive control group given normal saline 1 ml/100 g BW (Group B, n=5), AD rats model followed by Donepezil treatment (Group C, n=5), AD rats model with BUMSC-CM 0.2 ml/kg BW post-TMT induction (Group D, n=5), and AD rats model with BUMSC-CM 0.5 ml/kg BW post-TMT induction (Group E, n=5). …”
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Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study by Erika Endzelytė, Daiva Petruševičienė, Raimondas Kubilius, Sigitas Mingaila, Jolita Rapolienė, Inesa Rimdeikienė

“…We hypothesized that integrating BCI into occupational therapy would result in measurable improvements in hand strength, dexterity, independence in daily activities, and cognitive function compared to baseline. <i>Materials and Methods</i>: An observational study was conducted on 56 patients with subacute stroke. …”
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Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…This study offers a genomic analysis of C. difficile, focusing on sequence types (STs), global distribution, antibiotic resistance genes, and virulence factors in its chromosomal and plasmid DNA.MethodsA total of 19,711 C. difficile genomes were retrieved from GenBank. …”
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Effects of single subanesthetic dose of oxycodone on pain and Th1/Th2 balance in patients after radical mastectomy by QU Na，ZHAO Xiaohong，NI Qiang

“…Objective To compare the effects of oxycodone and fentanyl on postoperative pain relief，immune balance of T-helper cells（Th），and adverse reactions in radical mastectomy. Methods A total of 120 female patients whounderwent elective radical mastectomy at Shanghai Public Health Clinical Center between December 2021 and January2024 were selected for this study. …”
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Effects of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression in the treatment of avascular necrosis of femoral he... by Lei Sun, Ziyao Xu, Zhongyuan Zhang, Jinwei Zhao, Mengshuai Sun, Guangling Gao, Fang Gao, Hongjiang Jiang, Changjun Ju

“…The objective of this study is to evaluate the effect of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression (MCD) in the treatment of ANFH. Methods A retrospective cohort analysis comparing two surgical interventions was conducted between January 2020 and December 2020. …”
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Qualitative and quantitative ultrasound parameters of carotid atherosclerotic plaques in patients with moderate cardiovascular risk according to the SCORE scale: 7-year prospective... by O. A. Pogorelova, M. I. Tripoten, I. S. Melnikov, L. Sh. Khamchieva, B. M. Tamaeva, S. G. Kozlov, T. V. Balakhonova

“…To assess asymptomatic carotid atherosclerosis in patients with moderate cardiovascular risk over a 7-year prospective follow-up using non-invasive ultrasound markers.Material and methods. Eighty patients (47 men and 33 women) aged 53,1±5,9 years with moderate Systematic Coronary Risk Evaluation (SCORE) level, low-density lipoprotein cholesterol (LDL-C) of 2,7-4,8 mmol/l and asymptomatic hemodynamically insignificant (stenosis &lt;50%) carotid atherosclerosis (CA). …”
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Comparison of Milligan-Morgan Haemorrhoidectomy versus Laser Haemorrhoidoplasty in Patients with Grade II and III Haemorrhoids: A Prospective Observational Study by Asfar Ahamed Nawabjan, Sathish Rajkumar, Chudar Arumugam, Mohamed Marzook, Jasmine Sharmila, Lalith Kumar

“…Aim: To compare the clinical outcomes of Milligan-Morgan haemorrhoidectomy and laser haemorrhoidoplasty in patients with grade II and III haemorrhoids, focusing on postoperative pain, hospital stay, complications, and recovery time. Materials and Methods: A prospective observational study was conducted in the Department of General Surgery at Sri Lalithambigai Medical College and Hospital, Chennai, Tamil Nadu, India, from January 2022 to June 2023 (including three months of follow-up). …”
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Anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids by Yuan Ke, Lei Yinfu, Chen Lina, Yu Lelai, Liu Huan, Shen Qingbo, Huang Qi, Pei Xi

“…[Objectives] To investigate the effect of anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids. [Methods] Eighty patients with mixed hemorrhoids treated at our hospital between May 2019 and May 2020 were recruited and randomly assigned to the treatment and control group using the random number table. …”
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Safety and efficacy of robot-assisted percutaneous kyphoplasty under local anesthesia in a day-surgery setting for osteoporotic vertebral compression fractures by Yaming Wu, Yang Yuan, Yi Yin, Yaqin Gong, Yaowei Ye, Li Wu, Lizhen Qian

“…This retrospective study evaluates the safety and efficacy of robot-assisted percutaneous kyphoplasty (PKP) performed under local anesthesia within a day-surgery framework.MethodsClinical data from 127 patients with OVCFs who underwent robot-assisted PKP under local anesthesia in a day-surgery setting at the First People's Hospital of Kunshan between May 2022 and April 2024 were retrospectively analyzed. …”
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Knowledge of telemedicine and its associated factors among health professional in Ethiopia: A systematic review and meta-analysis. by Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Agmasie Damtew Walle, Addisalem Workie Demsash, Geleta Nenko Dube, Abiy Tasew Dubale, Sisay Yitayh Kassie, Gemeda Wakgari Kitil, Mesafint Zewold Jember, Chernet Desalegn Gebeyehu, Aster Temesgen Ariger, Eshetie Andargie Dires

“…This review evaluates Ethiopian-specific telemedicine knowledge and associated factors.<h4>Methods</h4>This systematic review was conducted using a search of several online databases in addition to the main databases, like Medline, PubMed, Scopus, and Science Direct. …”
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Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiorit... by Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G

“…Hence, we hypothesized that the analgesic effect of 0.25% ropivacaine would be noninferior to that of 0.375% ropivacaine at the same volume and would reduce the degree of weakness.Patients and Methods: In this randomized, double-blind, self-paired, noninferiority trial, 31 patients who were scheduled for similar, elective, bilateral foot and ankle surgeries under general anesthesia combined with popliteal sciatic and saphenous nerve blocks were enrolled. …”
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Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The &ldquo;Village Bondeko&rdquo; Center, In Kinshasa by Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

“…Thus, the objective of the present study was to investigate the relationship between sensorineural hearing loss and cognitive disorders in a correlational approach.Methods: This is a cross-sectional and analytical study conducted in the ENT department of the Center for the Disabled (visual, auditory, and mental) “Village Bondeko”, from June to September 2023, involving 150 adults (≥ 20 years) with acquired sensorineural hearing loss; without a history of neuropsychic disorders. …”
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Assessment of publication time in Campbell Systematic Reviews: A cross‐sectional survey by Bei Pan, Long Ge, Xiaoman Wang, Ning Ma, Zhipeng Wei, Lai Honghao, Liangying Hou, Kehu Yang

“…There was no significant difference between Campbell coordinating groups' median publication times and time gap from searches of databases to full review publication existed. However, the methods group only published one full review with almost a 3‐year time gap from searches of databases to review publication. …”
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