A RT-ERA-CRISPR/Cas12a assay for rapid point-of-care duck hepatitis A virus detection by Di Sun, Yukun Zhu, Mingshu Wang, Jingming Wang, Wenze Cheng, Zheng Li, Yuan Deng, Xumin Ou, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Yu He, Zhen Wu, Anchun Cheng

“…Isothermal amplification technologies are often combined with lateral flow assays or visual readout methods for detecting pathogen nucleic acids in non-laboratory settings. …”
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EULAR standardised training model for ultrasound-guided, minimally invasive synovial tissue biopsy procedures in large and small joints by Annamaria Iagnocco, Andrew Filer, Gabriel Herrero-Beaumont, Peter Balint, Ingrid Moller, Esperanza Naredo, Lene Terslev, Alessandra Bruns, Aurélie Najm, Ana Rodriguez, Raquel Largo, Stefano Alivernini, Jesús Garrido, Maria Antonietta D’Agostino, Jacqueline Uson, Juhani Koski, Maribel Miguel, Carlos Guillén-Astete, David A. Bong, George A.W. Bruyn, Carlos Acebes

“…Objectives To develop an EULAR training model for education in synovial tissue biopsy (STB) under ultrasound guidance (UG) following a stepwise approach: (1) development of educational material on UGSTB in large and small joints; (2) assessment of the validity, reliability and feasibility of the UGSTB educational procedure on cadaveric specimens; (3) validation of this procedure in live patients.Methods Using a nominal group (NG) and a DELPHI consensus methodology, educational audio-visual (AV) material and minimal requirements for education in UGSTB were developed by an expert panel. …”
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Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural E... by Iza Ciglenecki, Nombuso Ntshalintshali, Esther Mukooza, Skinner Lekelem, Mpumelelo Mavimbela, Sindisiwe Dlamini, Lenhle Dube, Nomvuyo Mabuza, Melat Haile, Tom Ellman, Antonio Flores, Olivia Keiser, Sindy Matse, Roberto de laTour, Alexandra Calmy, Bernhard Kerschberger

“…We nested a diagnostic accuracy study within a larger study of the burden of sexually transmitted infections in rural Eswatini. Methods Adults were enrolled at six routine HIV testing sites (HTS) in the Shiselweni region between June 2022 and April 2023. …”
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A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy by Young-Hee Cho, Young-Hee Cho, Chi-Ah Chun, Chi-Ah Chun, Hector Ramos, Paul Buonora, Paul Buonora, Paul Buonora, Vasanthy Narayanaswami, Vasanthy Narayanaswami, Kim-Phuong L. Vu, Kim-Phuong L. Vu

“…Its second aim was to investigate whether applicants who were accepted to the programs using a holistic selection process differed in academic discipline, demographics, and psychosocial characteristics from applicants who were not accepted.MethodsInformation on students’ majors, race/ethnicity, and gender was obtained from the university records or applications submitted by students. …”
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Whole-body and site specific [18F]FDG uptake patterns on PET/CT have limited value in differentiating between polymyalgia rheumatica and other inflammatory diseases: two cohorts of... by Andreas Wiggers Nielsen, Gijs D. van Praagh, Kornelis S. M. van der Geest, Ib Tønder Hansen, Berit Dalsgaard Nielsen, Søren Geill Kjær, Jesper Blegvad-Nissen, Kate Rewers, Christian Møller Sørensen, Elisabeth Brouwer, Ellen-Margrethe Hauge, Lars Christian Gormsen, Riemer H. J. A. Slart, Kresten Krarup Keller

“…Therefore, this study aimed to investigate both the overall whole-body [18F]FDG-uptake patterns and the specific uptake patterns at individual sites in patients suspected of having PMR. Methods Two distinct cohorts of patients with suspected PMR from Denmark and the Netherlands were prospectively included, encompassing 66/27 and 36/21 PMR/non-PMR patients, respectively. …”
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Domestic violence and its determinants among reproductive-age women in Sub-saharan Africa: a multilevel analysis of 2019–2024 demographic and health survey data by Girum Nakie, Gebresilassie Tadesse, Setegn Fentahun, Gidey Rtbey, Fantahun Andualem, Getasew Kibralew, Mulualem Kelebie, Mamaru Melkam, Techilo Tinsae, Mulat Awoke Kassa, Tekletsadik Tekleslassie Alemayehu, Muluken Yigezu, Tigist Kifle Tsegaw, Tesfaye Segon, Yilkal Abebaw Wassie

“…This study utilizes data from the 2019–2024 Demographic and Health Survey (DHS) to determine the prevalence of domestic violence among reproductive-age women in Sub-Saharan African countries and its associated factors. Methods A cross-sectional study design was used through multilevel logistic regression analysis. …”
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Modifying exercise and physical therapy in medical rehabilitation to promote a physically active lifestyle: Protocol for a multicenter controlled hybrid type 2 effectiveness-implem... by Eva Grüne, Johannes Carl, Wolfgang Geidl, Johanna Popp, David Victor Fiedler, Natalie Boss, Regina Brinkmann, Juliane von dem Bussche, Gabi Eichner, Kathrin Kleinert, Christoph Löhr, Florian Mex, Paul Schwanitz von Keitz, Till Richter, Joachim Schmidt, Rainer Tischendorf, Gorden Sudeck, Klaus Pfeifer

“…The objectives of the STABEKO study are A) to evaluate the implementation of modified exercise and physical therapy and to identify influencing factors for development and implementation, and B) to determine the short- and long-term effectiveness of the modified therapy on PAHCO and physical activity of the persons undergoing rehabilitation. Methods As part of the STABEKO study, we will use cooperative planning as a co-creation approach for planning, developing, and implementing actions to modify exercise and physical therapy by engaging relevant actors from practice, policy, and research in an equal decision-making process. …”
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Effects of Varying Text Message Length and Driving Speed on the Disruptive Effects of Texting on Driving Simulator Performance: Differential Effects on Eye Glance Measures by Rimzim Taneja, Kawther Alali, Mohammed, Ki-Jana Malone, Brandon Buchanon, Ashley Blanchette, Dung Ho, Doreen Head, Randall Commissaris

“…Eye glances off the roadway are a measure of the visual distraction associated with texting while driving. …”
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Factors influencing the course of post-COVID-19-related symptoms: A bidirectional cohort study among employees in health and welfare services in Germany by Steinke, Lara, Peters, Claudia, Nienhaus, Albert, Bethge, Matthias, Koch, Peter

“…Objective: The aim of this study was to determine the prevalence and trajectory of persistent symptoms following COVID-19 and to investigate factors influencing these among employees in the health and welfare services in Germany.Methods: This exploratory, mixed retro- and prospective cohort study using paper-and-pencil questionnaires was conducted among insured persons of the German Social Accident Insurance Institution for the health and welfare services with a SARS-CoV-2 infection in 2020. …”
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Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional... by Aditya Kumar Singh, Akshat Mittal, Manvendra Singh Rawat, Sanjay Dalakoti, Anil Kumar Joshi, Pavneesh Kumar Lohan, Chandra Shekhar, Indrajit Das Bhoumik

“…Aim: To compare clinical and functional outcomes of cemented BH versus PFNA in elderly patients with unstable intertrochanteric femur fractures. Materials and Methods: A prospective interventional study was conducted at Department of Orthopaedics, Government Doon Medical College and Associated Hospital, Dehradun, Uttarakhand, India, from July 2023 to December 2024. …”
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Assessing the Use of BotulinumtoxinA for Hyperactive Urinary Tract Dysfunction a Decade After Approval: General Versus Local Anesthesia for BotulinumtoxinA Detrusor Injection by Heinrich Schulte-Baukloh, Apostolos Apostolidis, Catarina Weiss, Thorsten Schlomm, Sarah Weinberger, Dirk Höppner, Kathrin Haberecht, Carsten Waskow, Hendrik Borgmann, Jörg Neymeyer, Bernhard Ralla

“…We examined the level of anxiety and pain experienced by patients who wanted to have the procedure performed under LA or general anesthesia (GA). <b>Material and Methods</b>: Patients scheduled for OnabotA DI were able to choose the anesthesia procedure (LA or GA). …”
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Clinical characteristics and surgical treatment comparison of multisegmental spinal tuberculosis: a retrospective analysis by Zongqiang Yang, Zongqiang Yang, Zhangui Gu, Zhangui Gu, Qiang Liu, Qiang Liu, Long Ma, Le Fei, Le Fei, Ningkui Niu, Ningkui Niu, Jiandang Shi

“…BackgroundTo analyze the therapeutic efficacy of intervertebral surgery in the treatment of multisegmental spinal tuberculosis (MSTB) by evaluating its clinical outcomes and perioperative indicators, thereby providing evidence-based insights to optimize surgical strategies and improve clinical decision-making.MethodsThis retrospective cohort study analyzed 134 MSTB patients treated at our hospital between January 2000 and June 2022. …”
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Prediction of solid pseudopapillary tumor invasiveness of the pancreas based on multiphase contrast-enhanced CT radiomics nomogram by Dabin Ren, Liqiu Liu, Aiyun Sun, Yuguo Wei, Tingfan Wu, Yongtao Wang, Xiaxia He, Zishan Liu, Jie Zhu, Guoyu Wang

“…ObjectivesTo construct a multiphase contrast-enhanced CT-based radiomics nomogram that combines traditional CT features and radiomics signature for predicting the invasiveness of pancreatic solid pseudopapillary neoplasm (PSPN).MethodsA total of 114 patients with surgical pathologic diagnoses of PSPN were retrospectively included and classified into training (n = 79) and validation sets (n = 35). …”
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Effect of Traditional Chinese Medicine collapse stains combined with western medicine in treating acute herpes zoster (中药溻渍联合西医治疗急性期带状疱疹的疗效观察)... by YAO Meiyu (姚美玉), SUN Mingli (孙明丽), TANG Ling (唐玲), ZHOU Jie (周洁), CHEN Hong (陈宏)

“…Objective To investigate the effect of Traditional Chinese Medicine (TCM) collapse stains combined with western medicine in treating acute herpes zoster. Methods A total of 60 patients with acute herpes zoster were randomly divided into observation group and control group, with 30 cases in each group. …”
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Prevalence of falls and associations with family functioning among community-dwelling older adults in Guangzhou, China by Si-Yu Sun, Zhi-Wei Wang, Zhi-Li Peng, Le-Xin Yuan, Wen-Hao Yang, Wen-Jian Zhang, Jia-Min Chen, Wei-Quan Lin, Wei Zhu, Wei Zhu

“…Consequently, this study aims to investigate the prevalence and influencing factors of falls among community-dwelling older adults in Guangzhou, China, with a particular emphasis on the impact of family functioning.MethodsWe used a multi-stage stratified cluster random sampling technique to successfully survey 2,399 individuals aged 65 and above across 11 districts in Guangzhou City. …”
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Efficacy of topical Raphanus sativus seed powder mixed with honey versus hydroquinone 4 % cream in the treatment of melasma – A randomized controlled trial by Arshan Horti, Shaikh Nisar Ahmed Abbas, Shavana Fathima, Mamadapur Saba Abdul Razzaq, Arsheya Parvez Mistry, Farooqui Shazia Parveen, Nazim Husain

“…Objective: This study aims to scientifically evaluate and compare the safety and efficacy of topically applied Raphanus sativus seed powder and honey mixture versus hydroquinone (4 % w/w) cream for melasma treatment. Methods: In this 8-week open-label, randomized controlled trial, 40 participants (20 per group), aged 18–65 years and diagnosed with melasma, successfully completed the study. …”
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Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study by Ramón González-Matilla, Ramón González-Matilla, Ramón González-Matilla, Vanesa Abuín-Porras, Isabel Mínguez-Esteban, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo

“…This study aims to evaluate differences in muscle tone, stiffness, ROM, and pain perception between children with CP and typically developing peers using objective biomechanical measures.MethodsAn observational, cross-sectional study was conducted with 40 participants of both sexes (20 children with CP, 20 typically developing peers). …”
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Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment by Annette H M van der Helm-van Mil, Pascal H P de Jong, Sytske Anne Bergstra, Elise van Mulligen, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Maikel van Oosterhout, Jos H van der Kaap, Selinde V J Snoeck Henkemans, Anne-Fleur van den Biggelaar

“…Therefore, we aimed to determine the difference in disease impact between matched RA and PsA patients at diagnosis and after 1 year in two different regions.Methods RA patients from the treatment in the Rotterdam Early Arthritis CoHort trial (tREACH), PsA patients from the Dutch southwest Early PsA cohoRt (DEPAR) and RA and PsA patients from the Leiden Early Arthritis Clinic (EAC) were included. …”
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Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled... by Chenghui Lu, Xuan Zhou, Chenglong Yang, Xinxiang Jiang, Xin Li, Zefan Huang, Qing Du, Guoyao Tang

“…The coprimary outcome measures were changes in visual analogue scale (VAS) scores and the overall response rate between baseline and 7 weeks of treatment. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…This study aimed to evaluate the effects of Naturagen® 4 Joint product containing type I, II, and III collagen on pain, quality of life, and physical functions in patients with meniscopathy. Methods This randomized, double-blind, placebo-controlled clinical study included 32 patients (collagen = 17 and placebo = 15) with meniscopathy. …”
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