The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

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Prediction model of ocular metastasis from primary liver cancer: Machine learning‐based development and interpretation study by Jin‐Qi Sun, Shi‐Nan Wu, Zheng‐Lin Mou, Jia‐Yi Wen, Hong Wei, Jie Zou, Qing‐Jian Li, Zhao‐Lin Liu, San Hua Xu, Min Kang, Qian Ling, Hui Huang, Xu Chen, Yi‐Xin Wang, Xu‐Lin Liao, Gang Tan, Yi Shao

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Novel allelic variants of blaOXA-48-like carried on IncN2 and IncC2 plasmids isolated from clinical cases in Argentina: In vivo emergence of blaOXA-567 by Juan Manuel de Mendieta, Denise De Belder, Nathalie Tijet, Barbara Ghiglione, Roberto G. Melano, Melina Rapoport, Pablo Power, Adriana Di Bella, Estefanía Biondi, Fernando Pasterán, Alejandra Corso, Sonia A. Gomez

“…The aim of this study was to analyse the phenotypic profile and dissemination strategies of two novel OXA enzymes, blaOXA-438 and blaOXA-567, located in Escherichia coli M17224 and Klebsiella pneumoniae M21014, respectively, isolated from two paediatric patients. Methods: Minimum inhibitory concentration measurements were performed to determine the phenotypic profile of the clinical isolates, transconjugants and transformant cells. …”
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Evaluation of optic disc parameters, circumpapillary retinal nerve fiber layer (cpRNFL) and ganglion cell complex (GCC) in refractive error using SS-OCT: Magnification-corrected an... by Jingyu Mu, Jing Wei, Zengrui Zhang, Haoming Geng, Fengyuan Yu, Junguo Duan

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Acupuncture for dry eye syndrome after refractive surgery: A randomized controlled pilot trial by Jun-Hwan Lee, Kyungsun Han, Tae-Hun Kim, Ae-Ran Kim, Ojin Kwon, Joo-Hee Kim, Jeong-Eun Kim, Seunghoon Lee, Mi-Suk Shin, So-Young Jung, Hyo-ju Park, Sanghun Lee

“…The objective of this study is to assess the feasibility of a study design for evaluating the effectiveness of acupuncture treatment along with usual care compared with usual care only for dry eye syndrome after refractive surgery. Methods: A total of 18 patients with dry eye syndrome occurring after refractive surgery participated in this study. …”
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Cross-frequency neuromodulation: leveraging theta-gamma coupling for cognitive rehabilitation in MCI patients by Xiao Yuan, Xiao Yuan, Zhilan Tu, Renren Li, Renren Li, Chenxi Pan, Chenxi Pan, Jing Ma, Jing Ma, Meng Liu, Dan Yang, Hualan Yang, Fangyun Li, Zhi Bie, Yixuan Ku, Yunxia Li, Yunxia Li

“…This study investigates how repetitive transcranial magnetic stimulation (rTMS) modulates gamma activity by regulating TGC to enhance WM in MCI patients.ObjectivesThis study aims to explore the effects of rTMS on WM by targeting TGC and reducing occipital gamma activity under varying WM loads.MethodsWe recruited 34 participants, including 20 MCI patients and 14 healthy elderly controls (HC), from Shanghai Tongji Hospital. …”
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Efficacy and Safety of Cold Atmospheric Plasma-Assisted Therapy for Herpes Zoster: A Randomized, Parallel, Positive-Controlled, Non-inferiority Multicenter Clinical Trial by Jingwen Wang, Ke Xue, Jing Gao, Chengda Yuan, Zebin Meng, Linge Li, Lili He, Chenchen Zhang, Xingyu Yang, Jing Wang, Yongmei Lv, Xin Du, Liyun Wang, Chuyu Fu, Na Wang, Yuyan Cheng, Feng Wang, Qing Li, Tingfang Zhang, Yong Cui, Chunjun Yang

“…We hypothesized that CAP was similar to or better than the helium–neon (He–Ne) laser in promoting HZ wound and pain recovery. Methods We recruited 187 patients with acute HZ who received either CAP once per day for at least 2 min per treatment area or He–Ne laser therapy once per day for 20 min per session, in addition to a standard treatment regime. …”
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Network pharmacology and experimental study of Angelica sinensis and Astragalus membranaceus capsules in treating heart failure by Xue Wu, Ai Liu, Xinfang Lv, Xiaodong Zhi, Xiangting Zeng, Kai Liu, Xinke Zhao, Bing Jiang, HuGang Jiang, Yingdong Li

“…Objective: This study explores the mechanism of AAC in intervening heart failure (HF) using network pharmacology, molecular docking, and in vitro experimental validation. Methods: The “active component-target” network and the “drug-disease target” protein interaction network were constructed using Cytoscape 3.9.0 and STRING Database. …”
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Patient with severe proliferative diabetic retinopathy and comorbidity: analysis of solved and unsolved problems in diabetic retinal involvement diagnosis and treatment from the po... by T. A. Novikova-Bilak, A. V. Zheleznyakova, O. E. Iljukhin, D. V. Lipatov, A. M. Nikolaeva, K. S. Turko, O. K. Vikulova, M. V. Shestakova

“…BACKGROUND: Diabetic retinal involvements as proliferative diabetic retinopathy (PDR) and diabetic macular edema (DME), revealed in most cases of PDR, are main causes of best corrected visual acuity (BCVA) loss in diabetic patients. PDR represents late diabetes mellitus (DM) complication, in severe cases it requires vitreoretinal surgery (VRS). …”
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Intelligence quotient discrepancy indicates levels of motor competence in preschool children at risk for developmental delays by Yu T, Chen K, Chou W, Yang S, Kung S, Lee Y, Tung L

“…The second finding was that preschoolers with larger VIQ>PIQ discrepancy had worse motor competence in visual-motor integration and body-movement coordination. …”
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Transversus abdominis plane block as a component of anesthesia in kidney transplantation by A. V. Shabunin, E. P. Rodionov, P. A. Drozdov, A. A. Malyshev, B. A. Smolev, A.  A.  Efanov, S.  A. Fedorishchev, R. I. Malashenko, S. A. Astapovich, E. A. Lidzhieva

“…To evaluate the safety and efficacy of the transversus abdominis plane block in kidney transplantation from deceased donor.Material and methods. The first stage included a retrospective comparative analysis of the results using the transversus abdominis plane block in renal transplantation. …”
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Effect of Clinic-Based and Asynchronous Video-Based Exercise on Clinic and Psychosocial Outcomes in Patients With Knee Osteoarthritis: Quasi-Experimental Study by Chidozie E Mbada, Henry Akintunji Awosika, Oluwatobi Ademola Sonuga, Micheal Akande, Tadesse Gebrye, Richard Woolf, Francis Fatoye

“…ObjectiveThis study aimed to examine the effect of a clinic-based strengthening exercise (CbSE) and asynchronous video-based strengthening exercise (AVbSE) on pain, range of motion, muscle strength, quality of life, and physical function among patients with knee osteoarthritis. MethodsA total of 52 consenting patients participated in this 8-week experimental study; they were assigned to the CbSE or AVbSE group at 2 different study sites. …”
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Twelve-Month Outcomes and Optical Coherence Tomography (OCT) Biomarkers After Intravitreal Dexamethasone Implantation in Pseudophakic Eyes with Post-Vitrectomy Cystoid Macular Edem... by Francesco Pignatelli, Alfredo Niro, Giuseppe Addabbo, Pasquale Viggiano, Giacomo Boscia, Maria Oliva Grassi, Francesco Boscia, Cristiana Iaculli, Giulia Maria Emilia Clima, Antonio Barone, Ermete Giancipoli

“…<b>Background</b>: In this study, we evaluated the incidence of cystoid macular edema (CME) after pars plana vitrectomy (PPV) for different retinal pathologies and assessed the role of optical coherence tomography (OCT) biomarkers in guiding treatment decisions in post-surgical CME patients who were refractory to medical therapy over a follow-up period of 12 months. <b>Methods</b>: Medical records of consecutive pseudophakic patients, who underwent PPV for different retinal pathologies, were retrospectively evaluated in this single-center, uncontrolled study. …”
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Revealing the Multi-Target Mechanisms of Fespixon Cream in Diabetic Foot Ulcer Healing: Integrated Network Pharmacology, Molecular Docking, and Clinical RT-qPCR Validation by Tianbo Li, Dehua Wei, Jiangning Wang, Lei Gao

“…<b>Objective:</b> This study aims to elucidate the potential mechanisms by which Fespixon cream promotes diabetic foot ulcer (DFU) healing using network pharmacology, molecular docking, and RT-qPCR validation in clinical tissue samples. <b>Methods:</b> Active components of Fespixon cream were screened from the Traditional Chinese Medicine Systems Pharmacology Database (TCMSP) and relevant literature, and their corresponding targets were standardized using the Universal Protein Resource (UniProt) database. …”
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Ondas de densidad semántica para el análisis de la argumentación clínica multimodal en la formación de profesionales de la salud by Giovanni Garcia-Castro, Francisco Javier Ruiz-Ortega

“…This study examines how semantic density, as conceptualized in the Legitimation Code Theory, and the use of multimodal resources contribute to developing argumentative skills in health sciences. Methods: Using a qualitative-comprehensive approach, a case study was conducted with five faculty members from the Adult Medicine department at the Technological University of Pereira. …”
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A Deep Learning Model for Identifying the Risk of Mesenteric Malperfusion in Acute Aortic Dissection Using Initial Diagnostic Data: Algorithm Development and Validation by Zhechuan Jin, Jiale Dong, Chengxiang Li, Yi Jiang, Jian Yang, Lei Xu, Ping Li, Zhun Xie, Yulin Li, Dongjin Wang, Zhili Ji

“…ObjectiveThis study aims to develop and validate a deep learning–based model that integrates multimodal data to identify patients with AAD at high risk of MMP. MethodsThis multicenter retrospective study included 525 patients with AAD from 2 hospitals. …”
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Optimizing Sports Training Lessons by Using the Led System for Beginner Basketball Groups by Adrian PAȘCAN, Cosmin MOCA

“…Materials and methods: The subjects of the experiment were the athletes of the beginner basketball group born in 2010-2011, namely 16 girls. …”
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Efectos del foam roller sobre el rango de movimiento, el dolor y el rendimiento neuromuscular: revisión sistemática (Foam roller effects on joint range of motion, pain, and neurom... by Blanca Romero-Moraleda, Alexandra López-Rosillo, Jaime González-García, Esther Morencos

“…Therefore, our goal was to carry out a systematic review to determine the effectiveness of foam rollers both during warm-ups and after exercising as a means for increasing recovery. Methods: A systematic review was performed in the scientific databases Pubmed, Wos, Scopus, and PEDro from November to March 2019. …”
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MYOCARDIAL INFARCTION AS TYPICAL PRESENTATION OF NONCOMPACTION CARDIOMYOPATHY by O. V. Blagova, A. V. Nedostup, E. V. Pavlenko, V. P. Sedov, E. A. Kogan, N. V. Gagarina, E. A. Mershina, V. A. Sulimov

“…To check the prevalence of acute MI in patients with NCM, the specialties of clinical picture, diagnostics, and its probable specific mechanisms, influence on prognosis and its ways of prevention.Material and methods. Totally, 10 patients included, 7 males and 3 females, mean age — 46,3±15,8 y. o., (30 to 76 y. o.) among 85 patients with verified NCM diagnosis, set in accordance with harmonized visual criteria, and developed MI on this background. …”
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A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical studies by Xiao-Min Lv, Na Li, Lin-Wei Chen, Cheng Sun

“…Furthermore, this study aims to reveal the underlying mechanisms of resveratrol related to the treatment of retina-related diseases.MethodsA search was conducted across several databases, including PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, Web of Science, and OVID. …”
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