Analgesic Efficacy of Thoracoscopic Direct-View Versus Ultrasound-Guided Thoracic Paravertebral Block in Multi-Port Video-Assisted Thoracoscopic Lung Surgery: A Randomized Controll... by Tong Y, Wu J, Wu X, Mo Y, Wang F

“…Yao Tong,1,* Jimin Wu,2,* Xuhui Wu,3 Yunchang Mo,1 Faxing Wang2,4 1Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Anesthesiology, Lishui People’s Hospital, Lishui Hospital of Wenzhou Medical University, Lishui, People’s Republic of China; 3Department of Thoracic Surgery, Lishui People’s Hospital, Lishui Hospital of Wenzhou Medical University, Lishui, People’s Republic of China; 4Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Lishui Hospital of Wenzhou Medical University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Yunchang Mo, Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, Shangcai Village, Nanbaixiang Street, Ouhai District, Wenzhou, Zhejiang, 325000, People’s Republic of China, Email myc1104@wmu.edu.cnPurpose: This study compares the analgesic effects of the Thoracoscopic Direct-view Thoracic Paravertebral Nerve Block (DTPVB) with those of the Ultrasound-guided Thoracic Paravertebral Nerve Block (UTPVB), providing a clinical reference.Patients and Methods: Sixty-eight patients undergoing three-port video-assisted thoracic surgery (VATS) with general anesthesia were randomly assigned to either the DTPVB group (Group D, n = 34) or the UTPVB group (Group U, n = 34). …”
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Dynamics of uric acid concentration against the background of early dapagliflozin use in patients with acute decompensation of heart failure by Laura H. Sarieva, Anastasiya E. Poskakalova, Svetlana N. Nasonova, Igor V. Zhirov, Sergey N. Tereshchenko

“…To evaluate the effect of sodium-glucose cotransporter type 2 inhibitor dapagliflozin in patients with ADHF with reduced left ventricular ejection fraction (LVEF) on uric acid levels. Materials and methods. The study included 122 patients with ADHF and reduced LVEF (28±6%), III FC 97 (79.5%) patients and II FC 25 (20.5%). …”
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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…This study is designed to further validate the efficacy and safety of the combination therapy of low-dose lenvatinib and PD-1 inhibitor toripalimab in patients with recurrent PROC.Study Design and Methods: The study is designed as a multicenter, open-label, single-arm, prospective phase II study. …”
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MAP17 is a Novel NASH Progression Biomarker Associated with Macrophage Infiltration, Immunotherapy Response, and Oxidative Stress by Huang Z, Chen J, Liu S, Xiang X, Long Y, Tan P, Fu W

“…However, the role of membrane-associated protein 17 (MAP17) in NASH remains unclear, which prompted this study to explore its relationship with immune infiltration and its regulatory mechanisms.Methods: We employed weighted correlation network analysis (WGCNA) to construct a gene co-expression network aimed at identifying key genes associated with NASH progression. …”
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Treatment With Schistosoma Japonicum Peptide SJMHE1 and SJMHE1-Loaded Hydrogel for the Mitigation of Psoriasis by Liu X, Wang S, Jiang Y, Luo X, Yang Y, Huo L, Ye J, Zhou Y, Yang Z, Du F, Dong L, Mao C, Wang X

“…This study evaluates the effects of the peptide SJMHE1 from Schistosoma japonicum (S. japonicum) on the inflammatory response in imiquimod (IMQ)-induced psoriasis mice and LPS-stimulated keratinocytes, as well as the efficacy of SJMHE1-loaded hydrogel on psoriasis in mice.Methods: SJMHE1 was administered to mice with IMQ-induced psoriasis via topical administration or subcutaneous injection, and effects were evaluated by detecting the skin inflammation of mice. …”
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A systematic review of evidence on the intersection of gender, sociocultural determinants of health, and antimicrobial resistance in a changing climate by Ms Ambika Lall, Dr. Vrinda Nampoothiri, Dr. Abdul Baasit Isaacs, Dr. Hope Mackline, Dr. Anastasia Koch, Dr. Deepshikha Batheja, Dr. Esmita Charani

“…Understanding the interaction between antimicrobial resistance (AMR), climate change, and gender will be critical to fighting infectious diseases in low- and middle-income countries (LMICs) and among the populations at greatest risk of AMR. Methods: A search was conducted on PubMed, Embase, and Web of Science on the intersection of gender, AMR, and climate. …”
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More Physical Exercise is Beneficial to Glycemic Control in Late Pregnancy Among Women with Gestational Diabetes Mellitus: Findings Based on Trajectory Model in a Prospective Cohor... by Zhang X, Ding Y, Duan Z, Cai R, Gao X, Zhang R, Wang R

“…This study aimed to explore this association using a group-based trajectory model (GBTM) among women with GDM.Patients and Methods: We constructed two types of models (A and B) by applying GBTM analysis based on a series of abnormal plasma glucose (PG) prevalence values calculated at each prenatal checkup in the GDM cohort. …”
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The Sensitive Genes for Cervical Cancer: Two-Sample Mendelian Randomization with Experimental Validation by Zhang R, Chai S, Chen Q, Lai J, Cai C

“…This study seeks to identify novel therapeutic targets to address this urgent clinical need.Methods: Our team identified differentially expressed genes (DEGs) in cervical cancer using gene expression omnibus (GEO) datasets. …”
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Cytokine Signatures as Biomarkers of Clinical Remission in Rheumatoid Arthritis by Su W, Xiao Y, Chen X, Wu Y, Wu B, Yang Q, Peng B, Tang J, Yang Y

“…This study aimed to investigate the potential of intricate cytokine networks for predicting the clinical remission of RA.Methods: In total, 164 patients with RA and 69 healthy individuals were included in this study. …”
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La Medicina Tradicional y Natural en el tratamiento de la estomatitis subprótesis by Ivonne Guerrero Ricardo, Yosvany Ramón Armas Pupo, Digna Norma Arévalo Rodríguez, Madelín Machado Coayo

“…Objective: to describe the application of the traditional natural medicine in the treatment of the subprosthesis stomatitis. Methods: a deep review about last year from January 2012 to September 2012 was done. …”
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Effect of Entecavir, Tenofovir Disoproxil Fumarate, and Tenofovir Alafenamideantiviral Therapy on Renal Function in Chronic Hepatitis B Patients: A Real-World Retrospective Study by Li Y, Li YW, Gao Y

“…This study aimed to assess the renal safety profile in NUC-experienced CHB patients who received ETV, TDF or TAF therapy.Methods: This retrospective observational cohort study investigated factors related to renal function in 154 patients with NUC-experienced CHB who received ETV, TDF, and TAF therapy for 48 weeks. …”
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Gui-Pi-Tang Defers Skeletal Muscle and Cardiac Muscle Aging by Promoting Mitochondrial Remodeling by Cai C, Wang M, Yang D, Jing C, Li Y, Xu H, Liu F, Zhao D

“…Changjiu Cai,1,* Manying Wang,2,* Dan Yang,2 Chenxu Jing,2 Yingna Li,3 Hanying Xu,4 Fangbing Liu,5 Daqing Zhao5 1Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 2Research Center of Traditional Chinese Medicine, Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 3College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 4Department of Encephalopathy, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China; 5Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fangbing Liu, Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China, Email liufb@ccucm.edu.cn Daqing Zhao, Northeast Asia Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China, Email zhaodaqing1963@163.comPurpose: To determine whether Gui-Pi-Tang (GPT) has protective effects on skeletal muscle and cardiac muscle in aged mice.Methods: This study used C57BL6/J mice to establish an in vivo natural aging model, while D-galactose (D-gal)-injured C2C12 and H9c2 cells were employed to create in vitro aging cell models. …”
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Screening and Verification COPD-OSA Overlap Syndrome Core Genes Using Bioinformatics by Qiang S, Wan R, Wu J, Wang C, Cui X, Zhang Y

“…To address this, we explored potential OS mechanisms using bioinformatics.Methods: OSA and COPD gene expression datasets were obtained from the Gene Expression Omnibus (GEO) database. …”
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One‐stage spatial mark–resight analysis reveals an increasing grizzly bear population with declining density near roads by Jesse Whittington, Mark Hebblewhite, Connor Meyer, Barb Johnston, Anne Forshner, Bryan J. Macbeth, Anthony L. Einfeldt, Seth G. Cherry

“…Both methods had >95% credible interval coverage and minimal bias. …”
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Effect of Lamotrigine on Refractory Epilepsy: Clinical Outcomes and EEG Changes by Li Z, Wu P, Chen Q, Tong X, Yang Q

“…Lamotrigine, with its proven efficacy and tolerability, offers potential benefits when combined with traditional medications like valproate, though its comprehensive impact on clinical outcomes and neurological markers requires further study.Objective: To analyze the improvement effect of combined application of lamotrigine on refractory epilepsy patients and its impact on patients’ EEG and neurological function.Methods: This retrospective cohort study analyzed the clinical data of 93 patients with refractory epilepsy who were admitted to our hospital between January 2023 and June 2024. …”
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Knowledge, Attitudes, and Practices Among Patients Undergoing Gastrointestinal Endoscopy in the Endoscopy Unit of a Tertiary-Care Hospital by Wei L, Niu Q, Ma L, Liu G, Zhang H, Zheng X, Lin Y, Du N, Li L

“…Our objective was to assess the KAP regarding gastrointestinal endoscopy in the Endoscopy Unit among those referred for diagnostic procedures.Patients and Methods: Patients scheduled for gastrointestinal endoscopy completed self-administered questionnaires to gather demographic information and evaluate their KAP scores. …”
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Contribution of Interleukin-1 Receptor-Associated Kinase 1 Gene Polymorphism to Systemic Lupus Erythematosus in Chinese Patients by Zhao L, Xu W, Du S, Xi F, Shi X, Liu R

“…The aim of the current study was to analyze the association between the IRAK1 polymorphisms (rs3027898 and rs1059702) and SLE in a Chinese cohort.Patients and Methods: A total of 150 SLE patients and 168 healthy controls of Chinese ethnicity were included in this study. …”
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Effects of Preoperative Magnesium Sulphate Infusion on Emergence Agitation and Postoperative Quality of Recovery in Patients Undergoing Thoracoscopic Lobectomy by Pu Y, Geng X, Wang M, Lv G, Hu Z, Fang C, Zhang X, Li W, Fan X, Chen X

“…This study aimed to examine the effects of preoperative magnesium sulphate infusion on emergence agitation and postoperative quality of recovery in patients undergoing thoracoscopic lobectomy.Patients and Methods: 84 patients undergoing thoracoscopic lobectomy were randomly assigned to either the magnesium sulphate group (group M) or the control group (group C). …”
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IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery by Cheng H, Ma J, Zhao F, Liu Y, Wu J, Wu T, Li H, Zhang B, Liu H, Fu J, He H, Zhu C, Ren H, Yang C, Qin S

“…Hao Cheng,1,* Jiao Ma,1,* Fengyu Zhao,2 Yiwei Liu,3 Jie Wu,4 Tao Wu,1 Hui Li,1 Boxiang Zhang,3 Hui Liu,5 Junke Fu,3 Haiqi He,3 Cailin Zhu,3 Hong Ren,3 Chengcheng Yang,2 Sida Qin3 1Department of Rehabilitation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 3Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 4Department of Radiation Oncology, Shaanxi Provincial People’s Hospital, Xi’an, Shaanxi, People’s Republic of China; 5Biobank, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Sida Qin, Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, 277 West Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China, Tel +86 15388666585, Email qinsida@xjtu.edu.cn Chengcheng Yang, Department of Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, 277 West Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China, Tel +86 17629260656, Email ccyang@xjtufh.edu.cnObjective: This research sought to assess the predictive potential of the inflammation-immunity-nutrition score (IINS) and the high-sensitivity C-reactive protein-albumin-lymphocyte (CALLY) index in individuals with NSCLC post-surgery.Methods: The study enrolled 506 patients with NSCLC undergoing R0 resection at the First Affiliated Hospital of Xi’an Jiaotong University. …”
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Effects of Short Naps on EEG Microstates: Improving Sleep Deprivation-Induced Cognitive Impairment by Ma C, Peng J, Li Y, Ouyang A, Huang Y, He W, Zhu Y, Fang P

“…This study aims to explore the effects of napping on cognitive impairments cause by SD and the potential mechanisms of cognitive recovery.Patients and Methods: We recruited forty-two healthy volunteers and recorded their EEG signals and psychomotor vigilance task (PVT) data at three time points: rested wakefulness, post-SD, and post-nap. …”
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