Improving Large Language Models’ Summarization Accuracy by Adding Highlights to Discharge Notes: Comparative Evaluation by Mahshad Koohi Habibi Dehkordi, Yehoshua Perl, Fadi P Deek, Zhe He, Vipina K Keloth, Hao Liu, Gai Elhanan, Andrew J Einstein

“…For this purpose, we aim to prove a hypothesis that summaries generated by LLMs of discharge notes in which detailed information is highlighted are likely to be more accurate than summaries of the original notes. MethodsTo test our hypothesis, we randomly sampled 15 discharge notes from the MIMIC III database and highlighted their detailed information using an interface terminology we previously developed with machine learning. …”
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Prediction of Clinical Bronchiectasis from Asymptomatic Radiological Bronchiectasis by Fan Y, Li Z, Jiang N, Zhou Y, Song J, Yu F, Zhang J, Wang X

“…Whether the ARB could progress to CB and the risk factors to speed up the process are poorly understood.Methods: This was an observational cohort study. 370 patients with radiological bronchiectasis were included in Wuhan Union Hospital in 2018. 296 ARB patients were followed up in 2022 to verify if they progressed to CB and divided the development and validation of clinical prediction models into a training set (n=207) and a validation set (n=89) by the ratio of 7:3. …”
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Telemedical treatment of diabetic foot ulcer in rural and remote areas: a prospective single centre randomised controlled clinical trial by Usman H Malabu, Venkat N Vangaveti, Julie Goodall, Jacqueline Bulbrook, Erik Biros, Harshal Deshmukh, Kunwarjit S Sangla

“…Therefore, our objective was to conduct a randomized controlled trial comparing the effectiveness of telemedical treatment in rural settings with the standard tertiary healthcare approach for managing diabetic foot ulcers. Methods The study was conducted between 2016 and 2022. …”
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GA-LDV: A Promising Derivative of 18β-Glycyrrhetinic Acid with Enhanced in vitro and in vivo Anti-Cancer Properties by Zheng J, Feng Q, Gao Q, Wang Y, Zhao S, Zhang X, Zhao M

“…Jiaying Zheng,1,* Qiqi Feng,1,* Qi Gao,1 Yaonan Wang,1 Shurui Zhao,1 Xiaoyi Zhang,1 Ming Zhao1,2 1Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, People’s Republic of China; 2Beijing Laboratory of Biomedical Materials and Key Laboratory of Biomedical Materials of Natural Macromolecules, Department of Biomaterials, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing, 100026, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Zhao, Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, People’s Republic of China, Tel +861083911535, Fax +861083911533, Email maozhao@126.com Xiaoyi Zhang, Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Capital Medical University, No. 10, Youanmenwaixitoutiao, Fengtai District, Beijing, 100069, People’s Republic of China, Tel +861083911530, Fax +861083911533, Email zhangdd@ccmu.edu.cnPurpose: The clinical translation of 18β-Glycyrrhetinic acid (GA) is impeded by its relatively low antitumor potency and poor aqueous solubility, we developed a novel derivative of GA by incorporating the Leu-Asp-Val (LDV) tripeptide to enhance its anti-tumor and anti-metastatic activities both in vitro and in vivo, thereby increasing its potential as a therapeutic agent for cancer treatment.Methods: The water solubility of GA-LDV was evaluated. …”
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The Duration of Prophylactic Antibiotic Use for Esophageal Cancer Patients with Postoperative Infection and Nutritional Status by Ning D, Zhou L, Shi G, Fu M

“…Dong Ning,1,* Lin Zhou,2,* Guidong Shi,1 Maoyong Fu1 1Department of Thoracic Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of China; 2Department of Ultrasound, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dong Ning, Department of Thoracic Surgery, Affiliated Hospital of North Sichuan Medical College, No. 1, Maoyuan South Road, Shunqing District, Nanchong, Sichuan, 63000, People’s Republic of China, Email dongningcb@21cn.comObjective: To verify the hypothesis that “the prophylaxis use time of antibiotics after esophageal cancer (EC) surgery ≤ 24 hours is associated with a lower postoperative infection rate and improvement of nutritional indicators”, a retrospective cohort analysis was conducted to compare the infection incidence and differences in serum nutritional indicators among patients with different medication durations (< 24 hours, 24– 48 hours, > 48 hours), and to identify independent risk factors for postoperative infection.Methods: A retrospective analysis was conducted on the data of 566 patients who underwent EC surgery in Affiliated Hospital of North Sichuan Medical College from January 2020 to October 2022. …”
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3D-Printed PCL-Based Scaffolds with High Nanosized Synthetic Smectic Clay Content: Fabrication, Mechanical Properties, and Biological Evaluation for Bone Tissue Engineering by Furtado ASA, Cunha MHS, Sousa LMR, Brito GC, Verde TFCL, Filgueiras LA, Sobral-Silva LA, Santana MV, Sousa GF, Santos FEP, Mendes AN, Figueredo-Silva J, Maia Filho ALM, Marciano FR, Vasconcellos LMR, Lobo AO

“…The main challenge lies in achieving a uniform distribution of nanoceramics across low to high concentrations within the polymer matrix while preserving mechanical properties and biological performance essential for successful osseointegration.Methods: This study utilized 3D printing to fabricate PCL scaffolds enriched with nanosized synthetic smectic clay (LAP) to evaluate its effects on structural, chemical, thermal, mechanical, and degradative properties, with a focus on in vitro biological performance and non-toxicity. …”
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EPIDEMIOLOGY AND SURVIVAL OF PATIENTS WITH MALIGNANT TUMORS OF CONNECTIVE AND SOFT TISSUE by V. M. Merabishvili, O. F. Chepik, E. N. Merabishvili

“…To estimate dynamics of incidence of malignant tumors of connective and soft tissue on the basis of public reporting, to calculate the index accuracy and observed and relative survival rates by histological forms, including sarcomas. Material and methods. To perform a detailed study there were selected, for two periods of observation, respectively 1054 patients (1995–2001) and 919 patients (2002–2008). …”
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Cecal coccidiosis in Japanese quails (Coturnix Japonica): Eimeria tsunodai identification and comparative prophylactic phytochemotherapy with immune stimulant impact by Reham M. ElBakrey, Amal A.M. Eid, Ahmed A. ElKholy, Mohamed R. Mousa, Mohamed A. El-Morsy, Walaa S. Abdelaziz

“…A selected E. tsunodai was used to evaluate the comparative anticoccidial efficacy of a commercial herbal product containing oregano and garlic essential oils (EOs) as a prophylactic supplement via drinking water taking into consideration that it had never been applied in quails' coccidiosis before. Methods: A total of 300 Japanese quails were equally assigned to four groups. …”
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Eepidemiological Interregional Multicenter Study of Healthcare-Associated Infections in the Intensive Care Units. First Results by R. V. Polibin, E. B. Brusina, O. V. Kovalishena, E. V. Glushkova, A. A. Gridina, B. I. Aslanov, N. I. Briko

“…The intensive development of medical technologies is accompanied by equally rapid changes in the epidemic process of healthcare-associated infections (HAIs). …”
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Integration of Diaphragmatic Ultrasonography and Intra-Abdominal Pressure Measurement for Optimizing Weaning from Mechanical Ventilation by Su D, Li R, Chen Z, Cui N, Yu Z, Ding X, Wu J

“…Dan Su,1,* Ruixin Li,1,* Zhi Chen,2 Na Cui,1 Zhanbiao Yu,1 Xiaoxu Ding,1 Jiaqian Wu1 1Intensive Care Unit, The Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China; 2Department of Hepatobiliary Surgery, The Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhi Chen, Department Hepatobiliary Surgery, The Affiliated Hospital of Hebei University, No. 212 of Yuhua Road, Lianchi District, Baoding, Hebei Province, 071000, People’s Republic of China, Tel +86 13832296881, Fax +86 0312-5983782, Email chenzhi6295@126.com Na Cui, Intensive Care Unit, The Affiliated Hospital of Hebei University, No. 212 of Yuhua Road, Lianchi District, Baoding, Hebei Province, 071000, People’s Republic of China, Tel +86 13503382865, Fax +86 0312 5983752, Email nacuilika@126.comObjective: The objective of this study was to evaluate the effectiveness of diaphragmatic ultrasonography in conjunction with intra-abdominal pressure (IAP) measurement for assessing diaphragm function and determining the optimal timing for weaning from mechanical ventilation (MV).Methods: A cohort of 100 patients undergoing MV at the intensive care department of the Affiliated Hospital of Hebei University between January 2023 and July 2023 was enrolled. …”
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Application Effectiveness of a Pre-Analytical Quality Management Pathway Based on the Structure–Process–Outcome Model by Cui L, Li W, Li Y, Feng X, Wang Y, Gao P

“…Liping Cui,1,* Wanling Li,1,2,* Yueqin Li,3 Xiaofang Feng,3 Yue Wang,4 Pei Gao4 1Department of Nursing, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, People’s Republic of China; 2Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of China; 3Department of General Medical, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, People’s Republic of China; 4Nursing College, Shanxi Medical University, Taiyuan, 030032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yueqin Li, Department of General Medical, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, No. 99 Longcheng Street, Xiaodian District, Taiyuan, Shanxi, 030032, People’s Republic of China, Tel +86 0351-8368114, Email li_yueqin@163.comObjective: This single-center, before-and-after study applied the structure–process–outcome (SPO) model to pre-analytical quality control to investigate its effect on laboratory testing quality, nursing practices, patient satisfaction, and clinician trust in test results.Methods: A before-and-after design was conducted in a provincial Class A tertiary hospital. …”
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Designing Survey-Based Mobile Interfaces for Rural Patients With Cancer Using Apple’s ResearchKit and CareKit: Usability Study by Alyssa Donawa, Christian Powell, Rong Wang, Ming-Yuan Chih, Reema Patel, Ralph Zinner, Eliah Aronoff-Spencer, Corey E Baker

“… BackgroundDespite the increased accessibility and availability of technology in recent years, equality and access to health-related technology remain limited to some demographics. …”
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Association of the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Neutrophil to High-Density Lipoprotein Cholesterol Ratio With the Severity of New-Onset Coronary Arter... by Shu H, Han S, Qiu W, Li J, Zhang X, Su H, Wu H, Zhao G, Li Q

“…However, the correlation between MHR, NHR, and the severity of newly diagnosed coronary artery disease (CAD) has not been thoroughly explored.Methods: In this retrospective study, we enrolled 1489 patients who underwent coronary angiography for the first time between January 2022 and December 2023, of which 1143 were diagnosed with CAD. …”
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Obesity and metabolic syndrome as risk factors for the development of non-alcoholic fatty liver disease as diagnosed by ultrasound by Petrović Gordana, Bjelaković Goran, Benedeto-Stojanov Daniela, Nagorni Aleksandar, Brzački Vesna, Marković-Živković Bojana

“…The aim of our study was to determine the importance of anthropometric and laboratory parameters as well as metabolic syndrome (MS) for the diagnosis of NAFLD and to estimate their influence on the degree of liver steatosis as evaluated by ultrasound (US). Methods. The study included 86 participants, 55 of whom had fatty liver diagnosed by ultrasound and they comprised the study group. …”
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Evaluation of Estimated Glucose Disposal Rate with Neutrophil-to-Lymphocyte Ratio Integrated for Prognosticating Adverse Cardiovascular and Cerebrovascular Events and Risk Stratifi... by Feng X, Liu Y, Yang J, Zhou Z, Yang S, Zhou Y, Guo Q

“…Xunxun Feng,1,2 Yang Liu,1 Jiaqi Yang,1 Zhiming Zhou,1 Shiwei Yang,1 Yujie Zhou,1,* Qianyun Guo1,* 1Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Medicine, Division of Cardiology, University of California, Los Angeles, CA, USA*These authors contributed equally to this workCorrespondence: Yujie Zhou; Qianyun Guo, Email azzyj12@163.com; gqydyx3000@163.comObjective: This research aimed to address the critical need for effective prognostic tools in patients with acute coronary syndrome (ACS) and type 2 diabetes mellitus (T2DM) undergoing percutaneous coronary intervention (PCI) by exploring the potential significance of integrating estimated glucose disposal rate (eGDR) and neutrophil-to-lymphocyte ratio (NLR).Methods: Major adverse cardiovascular and cerebrovascular events (MACCE) were the primary endpoint. …”
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Dysphagia and Body Composition in Cornelia de Lange Syndrome by Aleksandra Mędza, Aleksandra Cieszko, Małgorzata Gliwa, Michał Brzeziński, Jolanta Wierzba, Agnieszka Szlagatys-Sidorkiewicz, Katarzyna Sznurkowska

“…Dysphagia may be a sign or a complication of GERD (gastroesophageal reflux disease), which is the most frequent gastroenterological disorder in CdLS patients; Methods: Fourteen Polish patients with a clinical or genetic diagnosis of CdLS were included in the study. …”
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Characteristics of the Emotional and Behavioral Reactions of Rats under Chronic Stress Immobilization During Treatment with 5-R-thio-tetrazol [1,5-c] quinazoline Derivatives by О. Y. Tozyuk

“…RESEARCH MATERIALS AND METHODS. Chronic stress immobilization was modeled by keeping rats in small wooden cases for 16 hours / day for 18 days. …”
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Combination of Three Treatment Modes of 1064 nm Nd: YAG Laser in the Treatment of Melasma: A Retrospective Observational Study by Qiu H, Zhu Y, Wu B, Zhou S, Zhou X, Pan F

“…To investigate a more effective laser-based approach, this retrospective study evaluates the clinical outcomes of combining Low-fluence QS 1064 nm Nd: YAG laser, Fractional-mode QS 1064 nm Nd: YAG laser, and Long-pulsed 1064 nm Nd: YAG laser in the treatment of melasma.Methods: This retrospective observational study enrolled 43 patients with clinically diagnosed melasma, all of whom underwent treatment with a 1064 nm Nd: YAG laser using a combination of three modes: low-fluence QS, fractional-mode QS, and long-pulsed settings. …”
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Vertebral Osteoporosis in Systemic Lupus Erythematosus: A Possible Involvement of Inflammation-Related Osteoblast Ferroptosis by Lao Z, Chen X, Chen X, Zhang H, Zhang Z, Bian Y, Zhou C, Tian K, Jin H, Fu F, Wu C, Gan K, Ruan H

“…This study utilized the MRL/lpr mouse model, which effectively replicates human SLE manifestations, to investigate the impact of SLE on vertebral bone homeostasis.Methods: Female MRL/lpr mice were employed to investigate SLE-induced bone loss. …”
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Copper-Based Metal-Organic Framework Nanoplatform for miRNA Delivery: Synergistic Antitumor Therapy by Tu M, Deng X, Lai B, Liu J, Tao Y, Xu S, Li X, Niu X, Li Z, Huang J, Li J, Mao S, Ouyang X, Cao J

“…However, antioxidant mechanisms in tumor cells greatly reduce CDT efficacy.Methods: We propose using MOF-199 nanoparticles (NPs) with tumor microenvironment responsiveness as a carrier for miR-4521 to construct miR-4521@MOF-199 for cancer treatment. …”
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