Paroxysmal Sympathetic Hyperactivity, Volume Status, and Neurological Prognosis in Acute Brain Injury: A Prospective Cohort Analysis by Chen R, Cai X, Gui X, Lin G, Du W

“…Rongping Chen,1,* Xin Cai,2,* Xiying Gui,2 Guoying Lin,2 Wei Du3 1Department of Critical Care Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of Critical Care Medicine, Tibet Autonomous Region People’s Hospital, Lhasa, People’s Republic of China; 3Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Du, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China, Tel +13691018276, Email pink_dallas@126.comObjective: In this study, we enrolled patients with acute brain injury (ABI) to examine the relationship between paroxysmal sympathetic hyperactivity (PSH) and volume status, right heart function, and pulmonary edema, and their impact on prognosis.Methods: Thirty patients with ABI were prospectively enrolled. …”
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Research of subpopulation CD3+ CD4- CD8- double-negative T lymphocytes in kidney transplant recipients by S. V. Zybleva, S. L. Zyblev

“…To study changes in the values of CD3+CD4- CD8- double-negative T lymphocytes in peripheral blood in kidney transplant recipients.Material and methods. The study included 165 recipients who underwent kidney transplantation. …”
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IMAGES OF THE ELEMENTS IN N.A. LVOV`S WORLD ARTISTIC PICTURE by Elena N. Borowska

“…The purpose stipulates the usage of methods of both contextual (in the context of the scientific and aesthetic trends of the era) and immanent (addressed to the individual creative principles and features of Lvov’s worldview) analysis of the author’s poetic texts. …”
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The Danish Lymphoid Cancer Research (DALY-CARE) Data Resource: The Basis for Developing Data-Driven Hematology by Brieghel C, Werling M, Frederiksen CM, Parviz M, Lacoppidan T, Faitova T, Teglgaard RS, Vainer N, da Cunha-Bang C, Rotbain EC, Agius R, Niemann CU

“…However, access to large, shared datasets is largely missing and limits mAI research.Aim: Creating a large-scale data repository for patients with LC to develop data-driven hematology.Methods: We gathered electronic health data and created open-source processing pipelines to create a comprehensive data resource for Danish LC Research (DALY-CARE) approved for epidemiological, molecular, and data-driven research.Results: We included all Danish adults registered with LC diagnoses since 2002 (n=65,774) and combined 10 nationwide registers, electronic health records (EHR), and laboratory data on a high-powered cloud-computer to develop a secure research environment. …”
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Oxycodone vs the Combination of Fentanyl and Remifentanil for General Anesthesia in Laparoscopic Uterine Myomas Surgery: A Prospective, Randomized, Controlled Study by Xu X, Zhang H, Li J, Zhou L, Zhu S, Bao F

“…Xiaowei Xu,1,* Honggang Zhang,1,* Jun Li,2,* Li Zhou,1,3 Shengmei Zhu,1 Fangping Bao1 1Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310003, People’s Republic of China; 2Department of Anesthesiology, Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang Province, 310022, People’s Republic of China; 3Department of Pain Medicine, Ningbo No.6 Hospital, Ningbo, Zhejiang Province, 315040, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fangping Bao Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang Province, 310003, People’s Republic of China, Tel +8613958105226, Email baofp@zju.edu.cn Shengmei Zhu, Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang Province, 310003, People’s Republic of China, Tel +8613857169801, Email smzhu20088@zju.edu.cnPurpose: This study evaluated whether oxycodone alone could substitute for fentanyl combined with remifentanil for general anesthesia in laparoscopic uterine myoma surgery.Patients and Methods: 90 adult female patients were randomized into three groups: oxycodone 0.35 mg/kg (Group A), oxycodone 0.30 mg/kg (Group B), or fentanyl 5 μg/kg (Group C) for induction. …”
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The Resilience of Attitude Toward Vaccination: Web-Based Randomized Controlled Trial on the Processing of Misinformation by Benoît Béchard, Julie A Gramaccia, Dominique Gagnon, Elhadji Anassour Laouan-Sidi, Ève Dubé, Mathieu Ouimet, Delphine de Hemptinne, Sébastien Tremblay

“…Specifically, the goal was to investigate how misinformation presented in the style and layout of a news article could influence the perceived tentativeness (credibility) of COVID-19 vaccine information and confidence in COVID-19 vaccination. MethodsWe conducted a web-based randomized controlled trial by recruiting English-speaking Canadians aged 18 years and older from across Canada through the Qualtrics (Silver Lake) paid opt-in panel system. …”
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X-RAY PROGRESSION AND ITS IMPACT ON THE FUNCTIONAL STATUS OF PATIENTS WITH EARLY RHEUMATOID ARTHRITIS DURING A 5-YEAR FOLLOW-UP by Yu. A. Ermakova, D. E. Karateev, E. L. Luchikhina, N. V. Demidova, A. V. Smirnov

“…Objective: to assess progression of X-ray joint changes and their impact on functional status of patients with early rheumatoid arthritis (RA).Subjects and methods. The investigation enrolled 204 patients with early RA included in the RADICAL (Early Arthritis: Diagnosis, Outcomes, Criteria, Active Treatment) program in the period 2003 to 2007. …”
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Xijiao Dihuang Decoction for Sepsis-Induced Acute Lung Injury: Network Pharmacology and Molecular Dynamics Insights by Xu J, Jiao C, Du H, Guo X, Wang M, Ma Y, Yin Y, Liu M, Shao R

“…Jiaqi Xu,1– 3,* Conghan Jiao,2– 4,* Haiwei Du,2,5 Xiaojing Guo,1– 3 Mutian Wang,1– 3 Yuening Ma,1,2 Yanzhong Yin,1,2 Min Liu,1,2 Rongjiang Shao2,5 1Department of Infectious Diseases, the First Teaching Hospital of Tianjin University of TCM, Tianjin, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China; 3Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 4Department of Hematology, the First Teaching Hospital of Tianjin University of TCM, Tianjin, People’s Republic of China; 5Department of General Surgery, the First Teaching Hospital of Tianjin University of TCM, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Rongjiang Shao, Department of General surgery, The First Teaching Hospital of Tianjin University of TCM, No. 88, Changling Road, Xiqing District, Tianjin, 300381, People’s Republic of China, Tel +86 13920987128, Email 13920987128@163.com Min Liu, Department of Infectious Diseases, The First Teaching Hospital of Tianjin University of TCM, No. 88, Changling Road, Xiqing District, Tianjin, 300381, People’s Republic of China, Tel +86 13132296378, Email liumintcm@163.comObjective: This study investigates the therapeutic mechanisms of Xijiao Dihuang Decoction (XJDHD) in sepsis-induced acute lung injury (SALI) through an integrated approach, including network pharmacology, molecular docking, molecular dynamics simulations, and in vitro experiments.Methods: Network pharmacology identified active ingredients and targets in Xijiao Dihuang Decoction. …”
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The Application of Opacification-Development Ratio Based on CT Scan for Diagnosing Pediatric Chronic Rhinosinusitis by Zhang J, Yang A, Chen T, Cao Y, Lv Q, Xu Y, Liao Z, Chen X, Ye Z, Lai R, Hong H

“…Jun Zhang,1,* Anni Yang,1,* Tengyu Chen,1,* Yufeng Cao,1 Qiliang Lv,1 Yingxiang Xu,1 Zhenpeng Liao,1 Xianzhen Chen,1 Zhongkang Ye,1 Renjie Lai,1 Haiyu Hong1,2 1Department of Otolaryngology, Head and Neck Surgery, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong Province, People’s Republic of China; 2Allergy Center, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haiyu Hong, Department of Otolaryngology, Head and Neck Surgery, Allergy Center, The Fifth Affiliated Hospital of Sun Yat-sen University, 52 of Meihua East Road, Zhuhai, Guangdong, 519000, People’s Republic of China, Tel +8607562528832; +8613823070089, Email honghy@sysu.edu.cnPurpose: To investigate the diagnostic potency of the opacification-development ratio (ODR) for pediatric chronic rhinosinusitis based on CT scanning.Patients and Methods: Children aged 0– 15 years who underwent nasal CT scanning from August 2011 through July 2021 were included in the research. …”
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Effect of Age, Sex and Season on Acute Myeloid Leukemia Clinical Characteristics: A Retrospective Study by Wan X, Tao T, Zhang J, Li N, Gou Y, Yang W, Han X, Wu S, Zhang C, Peng X, Liu S, Zhang X

“…In order to elucidate the correlations between these factors, we performed a comprehensive data collection and analysis of AML patients in our hospital from 2013 to 2023.Methods: Totally, 2798 newly diagnosed AML patients and 220 relapsed AML patients who were admitted to our hospital from January 1, 2013 to December 31, 2023 were included for analysis. …”
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PLK1 Mediates the Proliferation and Contraction of Airway Smooth Muscle Cells and Has a Role in T2-High Asthma with Neutrophilic Inflammation Model by Pan Y, Xue Y, Fei X, Zhao L, Han L, Su H, Lin Y, Zhou Y, Zhang Y, Xie G, Kong D, Bao W, Zhang M

“…However, the downstream mediator of S1P remains unclear, as does its role in T2-high asthma with neutrophilic inflammation.Methods: Ovalbumin- and ozone-induced murine models were used to replicate T2-high asthma with neutrophilic inflammation and primary ASMCs were applied to explore the underlying effects. …”
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FFMI: A Pivotal Indicator Bridging Pulmonary, Sleep, and Systemic Factors in COPD–OSA Overlap Patients by Wang L, Shen YY, Qian RQ, Zhang XQ, Shen XR, Chen C

“…This study aims to compare the Fat - Free Mass Index (FFMI) between OVS and simple COPD patients and analyze subgroup differences in OVS for better early identification and severity assessment.Methods: Clinical data of 364 patients (203 in COPD group, 161 in OVS group) were analyzed regarding clinical features, pulmonary function, sleep apnea, etc. …”
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Persisting Short or Long Sleep Duration Predicts Post-Stroke Depression One year After Stroke and Transient Ischemic Attack by Hu Y, Zuo L, Pan Y, Yan H, Wang Y, Zhao X

“…However, the association of changes in sleep duration with functional outcome and depression after acute ischemic stroke (AIS) or transient ischemic attack (TIA) is still unclear.Methods: All patients diagnosed with AIS or TIA in the impairment of cognition and sleep (ICONS) from the China National Stroke Registry III were included. …”
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Combining Experimental Validation and Network Pharmacology to Reveal the Action Mechanism of Panax Notoginseng-Radix Salviae on Atherosclerosis by Song N, Zhang X, Yin H, Zhang L, Li C, Li J, Li Y, Wu J

“…This study aims to explore the potential bioactive ingredients and molecular mechanisms of PN-RS in the treatment of AS.Materials and Methods: C57BL/6J mice were fed a common diet as the control group. …”
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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…This study investigates the relationship between inflammatory indices and MAFLD in hypertensive patients and assesses the predictive accuracy of these indices for MAFLD.Methods: We performed a cross-sectional analysis involving 34,303 hypertensive patients from a Chinese hospital-based registry. …”
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Advances in Coking Wastewater Treatment and Zero Discharge Technology by Huaqiang CHU, GLADYS Chimfwembe, Pengyuan WEI, Jie XU, Guihong SHUI, Jiaying MA, Xuefei ZHOU, Yalei ZHANG

“…In recent years, considerable attention has been directed towards developing more efficient methods for treating coking wastewater. This review provides a comprehensive overview of current advancements in coking wastewater treatment technologies, focusing on their sources, characteristics, pretreatment technologies, biochemical treatments, and advanced treatment technologies. …”
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Self-Management Intervention for Reducing Epilepsy Burden Among Adult Ugandans with Epilepsy (SMART-U): Randomised Clinical Trial Protocol by Mbalinda SN, Kaddumukasa M, Najjuma JN, Birungi DR, Kaddumukasa MN, Levin JB, Still CH, Burant CJ, Modi AC, Katabira ET, Sajatovic M

“…The purpose of this 2-site randomised controlled experiment is to investigate this further, based on encouraging preliminary evidence.Methods: A total of 188 adult people with epilepsy (PWE) attending the neurology clinics at Mulago and Mbarara hospitals and consent to participate in the study will be recruited. …”
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Houttuynia cordata-Derived Exosome-Like Nanoparticles Mitigate Colitis in Mice via Inhibition of the NLRP3 Signaling Pathway and Modulation of the Gut Microbiota by Li JH, Xu J, Huang C, Hu JX, Xu HM, Guo X, Zhang Y, Xu JK, Peng Y, Zhang Y, Zhu MZ, Zhou YL, Nie YQ

“…This study aims to evaluate the efficacy of HELNs in treating colitis in mice and investigate its potential mechanisms.Methods: HELNs were isolated from H. cordata for characterization, and their safety and stability were evaluated. …”
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The Future of Hospital Medicine in Japan: Lessons From the United States Hospital Medicine System by Suzuki T, Katayama K, Houchens N, Hartley S, Tokuda Y, Watari T

“…Marianna University School of Medicine, Kanagawa, Japan; 3Medicine Service, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA; 4Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA; 5Muribushi Okinawa Center for Teaching Hospitals, Urasoe, Okinawa, Japan; 6Tokyo Foundation for Policy Research, Tokyo, Japan; 7Kyoto University Hospital, Integrated Clinical Education Center, Kyoto, Japan; 8General Medicine Center, Shimane University Hospital, Shimane, Japan*These authors contributed equally to this workCorrespondence: Takashi Watari, Shimane University Hospital, General Medicine Center, 89-1 Enya, Izumo city, Shimane prefecture, Shimane, Japan, Email wataritari@gmail.comPurpose: To compare hospitalist roles and training systems between the United States (US) and Japan, identifying strengths and challenges to guide development of Japan’s emerging hospital medicine program.Methods: A qualitative, descriptive narrative study was conducted during a 10-day observational site visit to the Veterans Affairs Ann Arbor Healthcare System and University of Michigan Hospital in October 2022. …”
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From medical school to global health leadership: 35-year career outcomes and gender disparities from the Aga Khan University Medical College by Adil H. Haider, Maham Vaqar, Asma Altaf Hussain Merchant, Sharjeel Ahmad, Komal Abdul Rahim, Namra Qadeer Shaikh, Noreen Afzal, Shayan Shah, Anum Rahim, Saad Bin Zafar Mahmood, Saqib Kamran Bakhshi, Sadaf Khan, Muhammad Tariq

“…With no published data using alumni surveys in the South Asian region, we set out to conduct a survey to gain insights into the career trajectories, professional milestones, and accomplishments of 35 graduating classes from one of Pakistan’s largest Academic Medical Centers (AMC). Methods An online survey was distributed to 2,177 alumni of the Aga Khan University (AKU), Pakistan who graduated from 1988 to 2021. …”
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