Health-Related Quality of Life with Cervical Cancer and Precancer: A Cross-Sectional Study in Yunnan Province, China by Min Zhao, Meng-Jiao Zhang, Lian-Ju He, Chun-Mei Zuo, Song-Rui Ding, Allison Rabkin Golden, Le Cai

“…This study investigates socioeconomic and clinical variations in HRQoL of women with cervical precancerous lesions and cervical cancer in Yunnan Province, China. Methods: The present study employed a cross-sectional survey design. …”
Get full text

Patient-reported outcomes and radiographic progression in patients with rheumatoid arthritis in sustained remission versus low disease activity by Annette H M van der Helm-van Mil, Pascal H P de Jong, Marijn Vis, Selinde V J Snoeck Henkemans, Agnes E M Looijen

“…Objective To compare clinical and patient-reported outcomes (PROs) over 5 years between patients with rheumatoid arthritis (RA) in sustained remission (sREM), sustained low disease activity (sLDA) or active disease (AD) in the first year after diagnosis.Methods All patients with RA from the treatment in the Rotterdam Early Arthritis CoHort trial, a multicentre, stratified, single-blinded trial with a treat-to-target approach, aiming for LDA (Disease Activity Score (DAS) ≤2.4), were studied. …”
Get full text

Gender-related differences in clinical presentation, electrocardiography signs, laboratory markers and outcome in patients with acute pulmonary embolism by Obradović Slobodan, Džudović Boris, Rusović Siniša, Subota Vesna, Obradović Dragana

“…The aim of this study was to identify gender-specific differences in clinical presentation, the diagnosis and outcome between male and female patients with PE. Methods. We analysed the data of 144 consecutive patients with PE (50% women) and compared female and male patients regarding clinical presentation, electrocardiography (ECG) signs, basic laboratory markers and six-month outcome. …”
Get full text

Open surgery and minimally invasive repair of acute Achilles tendon rupture: stratified outcomes based on immobilization duration in a prospective cohort study by Yuan Cao, Xiuzhi Li, Zengzhen Cui, Yang Lv, Gao Si

“…This prospective cohort study aimed to compare clinical outcomes of OS and MIS for AATR repair and evaluate the impact of immobilization duration (0, 2, or 4 weeks) on postoperative rehabilitation. Methods A total of 474 patients undergoing surgical repair for acute AATR were stratified into six groups based on surgical approach (OS: 265 cases; MIS: 209 cases) and immobilization duration (0, 2, or 4 weeks). …”
Get full text

Barriers and Facilitators to the Preadoption of a Computer-Aided Diagnosis Tool for Cervical Cancer: Qualitative Study on Health Care Providers’ Perspectives in Western Cameroon by Magali Jonnalagedda-Cattin, Alida Manoëla Moukam Datchoua, Virginie Flore Yakam, Bruno Kenfack, Patrick Petignat, Jean-Philippe Thiran, Klaus Schönenberger, Nicole C Schmidt

“…The aim was to guide smooth technology adoption in similar settings by identifying specific barriers and facilitators and optimizing CAD’s potential benefits while minimizing obstacles. MethodsThe perspectives of HCPs on adopting CAD for VIA were explored using a qualitative methodology. …”
Get full text

Clinical Value of Continuous Fascia Iliaca Compartment Block in Perioperative Management of Elderly Patients with Intertrochanteric Fracture: A Propensity Score-Matched Retrospecti... by Xu G, Deng Y, Gao H, Wang B, Wang G, Ma J

“…This study investigated the efficacy of continuous fascia iliaca compartment block (CFICB) in perioperative management.Methods: A retrospective analysis was conducted on elderly patients (≥ 65 years) with intertrochanteric fractures treated between January 2020 and December 2023. …”
Get full text

Antimicrobial peptides for treatment of patients with herpes virus-associated chronic prostatitis by E. V. Kulchavenya, S. Yu. Shevchenko, A. A. Baranchukova

“…To determine the efficacy of cytokines-antimicrobial peptides complex in therapy of patients with herpes virus-associated chronic prostatitis.Materials & methods. The pilot, open, prospective, non-comparative study included 23 patients who were followed up for CP for a mean of 9.7 ± 4.2 years. …”
Get full text

Proteomic and metabolomic analysis of serum in women infected with COVID-19 during late pregnancy by Yi Zheng, Jinyu Ning, Jiang Zhu, Honglin Zhu, Zhihua She, Pei Cai

“…IntroductionTo investigate the alterations of serum proteins and metabolomics in women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of pregnancy and their potential effects on fetal development.MethodsThe corona virus disease 2019 (COVID-19) group (n=31) included women in the third trimester diagnosed with SARS-CoV-2 infection and who delivered, while the control group (n=30) comprised uninfected women in the same gestational period. …”
Get full text

Integrated pan-cancer analysis of ADM’s role in prognosis, immune modulation and resistance by Yunhuan Liu, Caicun Zhou

“…This called for a pan-cancer analysis of ADM, investigating its expression, genomic alterations, prognostic value, immune associations, and relations with drug sensitivity to provide insights into its potential as a therapeutic target and biomarker.MethodsADM expression data from normal and tumor tissues was retrieved and analyzed through HPA and Timer 2.0 online platforms. …”
Get full text

Progressive Response of Repeated Treatment with High-Concentration (179 mg) Capsaicin Patch in Peripheral Neuropathic Pain After Surgical or Traumatic Nerve Injury: Findings from t... by Michael A. Überall, Christian Simanski, Mike Zellnig, Mariëlle Eerdekens, Sylvia Engelen, Myriam Heine, Fabienne Percot, Rita Freitas, Lucia Garcia Guerra, Tamara Quandel

“…This study utilizes data from the German Pain e-Registry (GPeR) to investigate the real-world effectiveness of HCCP in managing PNI across multiple treatments over 1 year. Methods CASPAR is a retrospective, non-interventional cohort study investigating patients with peripheral neuropathic pain treated with HCCP. …”
Get full text

Efficiency of surgical treatment of neovascular glaucoma: a retrospective analysis by A. V. Zolotarev, E. V. Karlova, M. V. Radaikina, A. A. Kuz'mina, O. V. Ryzhkova

“…The timely treatment of the underlying disease with Anti-VEGF and LC of the retina allows the patient to maintain visual functions, and increases the effectiveness of NVG surgery.…”
Get full text

Commercially available antiseptics show high in vitro efficacy against pathogens most commonly associated with canine and feline infectious keratitis by Hinrich Tönjes Wolff, Ana Cristina Piroth, Hilke Oltmanns, Jessica Meißner, Jutta Verspohl, Holger Andreas Volk, Claudia Busse

“…PurposeTo determine the minimal bactericidal concentration (MBC) of polyhexanide (PHMB), povidone-iodine (PVP-I), N-acetylcysteine (NAC), and hypochlorous acid (HOCl) for bacterial species commonly found in canine and feline infectious keratitis.MethodsMBCs for clinical isolates of Staphylococcus (S.) pseudintermedius (n = 11), including 3 methicillin-resistant strains, Pseudomonas (P.) aeruginosa (n = 8), and Streptococcus (Str.) canis (n = 11), including the corresponding control strains, were examined. …”
Get full text

Fourth-Generation Metatarsal Extra-Capsular Transverse Akin (META) Osteotomies for Percutaneous Hallux Valgus Correction: A Series of 729 Consecutive Feet by Peter Lam MBBS (Hons), FRACS, FAOA, Evelyn Murphy MBBCh BAO MCh FRCS (Tr & Orth), Min Jia Chua MB BS FRCSEd, Peter Robinson BSc(Hons), MBChB, FRCS(Tr & Orth), Clare Watt BNurs, Robbie Ray MBChB, ChM(T & O), FRCSed(TrOrth), FEBOT, Thomas L. Lewis BSc (Hons) MBChB (Hons) FRCS (Tr & Orth) MFSTEd

“…The aim of this study was to provide a methodological robust investigation into percutaneous transverse osteotomies for hallux valgus deformity. Methods: A prospective case series of consecutive patients undergoing fourth generation metatarsal extra-capsular transverse osteotomy (META) performed by a single surgeon (PL) between November 2017 and January 2023. …”
Get full text

Efficacy of Shock Wave Therapy Combined with Core Stability Training on Non-Specific Low Back Pain after Stroke by DAI Yayuan, WANG Xiaojun, YIN Jie, ZHU Wenjuan, SU Min

“…ObjectiveTo investigate the clinical efficacy of shock wave therapy combined with core stability training on non-specific low back pain (NLBP) after stroke.MethodsA total of 70 patients with post-stroke NLBP who visited Suzhou Xiangcheng People's Hospital from January 2022 to November 2023 were selected as the subjects of the study. …”
Get full text

Impact of the Exposome in Type 1 Diabetes: Protocol for a Scoping Review by Maurane Rollet, Gloria A Aguayo, Jean-Pierre Riveline, Emmanuel Cosson, Guy Fagherazzi

“…ObjectiveThis paper aims to present a protocol for a scoping review to gather current knowledge on the various dimensions of the exposome relevant to the development and outcomes of T1D, highlight existing knowledge gaps, and provide a foundation for future research. MethodsWe will follow principles from the Joanna Briggs Institute (JBI) methodology for scoping reviews and the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) guidelines. …”
Get full text

Surgeon reported measures of stress and anxiety prior to and after elective gynecological surgery by Aaron K. Budden, Sophia Song, Amanda Henry, Claire E. Wakefield, Jason A. Abbott

“…Secondary aims assessed any differences by level of training, surgical type, and surgeon role. Material and methods Attending and resident gynecologists performing routine elective surgeries completed a visual analog scale (VAS) assessing perceived stress and the State–Trait Anxiety Inventory (STAI) prior to and immediately after completing 161 elective surgeries including total laparoscopic hysterectomy, laparoscopic excision of moderate–severe endometriosis, or hysteroscopic myomectomy. …”
Get full text

Our Experience of Nutraceutical Effects in Age-Related Macular Degeneration by S. V. Yanchenko, A. V. Malyshev, S. N. Sakhnov, A. S. Balayan, A. A. Sergienko

“…Purpose: to assess the possibilities of ophthalmonutraceuticals using in age-related macular degeneration (AND) patients.Patients Methods. The study included 35 patients (68.3 ± 6.3 years old; 15 men, 20 women) with AMD (AREDS-2 and AREDS-3 categories). …”
Get full text

Multimodal ultrasound-based radiomics and deep learning for differential diagnosis of O-RADS 4–5 adnexal masses by Song Zeng, Haoran Jia, Hao Zhang, Xiaoyu Feng, Meng Dong, Lin Lin, XinLu Wang, Hua Yang

“…This study aims to develop and validate a multimodal US-based nomogram that integrates clinical variables, radiomics, and deep learning (DL) features to effectively distinguish adnexal masses classified as O-RADS 4–5. Methods From November 2020 to March 2024, we enrolled 340 patients who underwent two-dimensional US (2DUS) and CEUS and had masses categorized as O-RADS 4–5. …”
Get full text

Effect of Traditional Chinese Medicine fumigation and washing combined with fine nursing on postoperative pain of patients with hemorrhoids (中药熏洗联合精细化护理对痔疮患者术后疼痛的影响)... by CHEN Zhengrong (陈正荣)

“…Objective To investigate the effect of Traditional Chinese Medicine (TCM) fumigation and washing combined with fine nursing on postoperative pain of patients with hemorrhoids. Methods Totally 40 patients undergoing surgical treatment for hemorrhoids were assigned to the control group and observation group according to the hospital admission sequence. …”
Get full text

Comparison of efficacy and safety of combined phacoemulsification, goniosynechialysis and goniotomy with trabeculectomy in advanced primary angle-closure glaucoma: a retrospective... by Wenzhe Zhang, Pengyun Wang, Chen Wang, Wenhui Liu, Jiayin Wu, Lin Shen, Rachita Kurmi, Hui Guo

“…This study aimed to compare the intraocular pressure (IOP) lowering effect of phacoemulsification combined with intraocular lens implantation (PEI), Goniosynechialysis (GSL), and goniotomy (GT) vs. trabeculectomy (TRAB) in eyes with medically uncontrolled advanced primary angle-closure glaucoma (PACG) at a 12-month follow-up.MethodsPatients with medically uncontrolled advanced PACG with 360° peripheral anterior synechia (PAS) were included in this study. …”
Get full text