Effect of ropivacaine scalp nerve block on postoperative recovery quality after craniotomy by LI Wenjing, LIAO Jinwen, HEI Ziqing, CAI Jun, XING Jibin

“…Objective To evaluate the effect of 0.5% ropivacaine for scalp nerve block on postoperative pain and recovery quality in craniotomy patients， and provide a reference for optimizing clinical anesthesia plans. Methods Sixty-six patients scheduled for craniotomy under general anesthesia were selected and randomly divided into ropivacaine group （R group） and control group （C group） in a 1∶1 ratio. …”
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Intraosseous endoscopic-assisted lesion debridement combined with free fibular vascularized transplantation for non-traumatic femoral head necrosis: A comparative study with core d... by Yalong Yang, Zhao Zhang, Yuanyuan Wei, Yang Li, Junliang Liu, Bo Wang, Shouhu Mi, Jintong Liu, Yongqiang Zhang, Yongming Guo, Meng Wu

“…This study compares the efficacy of endoscopy-assisted lesion debridement with free vascularized fibular grafting versus core decompression (CD) to identify a more effective surgical approach for treating osteonecrosis of the femoral head (ONFH). Methods This retrospective study included 83 patients with femoral head necrosis who were treated between January 2010 and December 2020. …”
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Predicting student achievement through peer network analysis for timely personalization via generative AI by Ivica Pesovski, Petar Jolakoski, Vladimir Trajkovik, Zuzana Kubincova, Michael A. Herzog

“…Building on these clusters, a novel AI-driven approach is introduced to personalize the learning experiences for each group, providing content aligned with students' predicted achievement levels and ensuring that students receive the right resources throughout their entire education. Methods: Bi-weekly surveys were conducted throughout the academic year with 45 students enrolled in a computer science program, where students nominated up to five peers they collaborated with the most. …”
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Decades of discovery: unveiling emerging trends, pivotal research areas, and landmark publications in national tobacco research in India by Alok Singh, Akanksha Kashyap, Saurabh Varshney, Sudip Bhattacharya

“…However, there is a need to map the growth and direction of this research to identify strengths, gaps, and emerging trends within the Indian context.MethodsA bibliometric analysis was conducted to evaluate tobacco-related research output affiliated with Indian institutions between 2003 and 2024. …”
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A prospective study on the effects of glucosamine hydrochloride and chondroitin sulfate combination on systemic inflammation markers in patients with knee osteoarthritis (report 1) by A. M. Lila, E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, N. M. Savushkina, N. M. Savushkina, T. A. Korotkova, A. S. Avdeeva, E. Yu. Samarkina, M. E. Diatroptov

“…Objective: to assess the effect of a combination of glucosamine hydrochloride (GH) 500 mg and chondroitin sulfate (CS) 500 mg (Artra®) on systemic inflammation markers in patients with knee osteoarthritis (KOA).Material and methods. The study included 70 patients with a confirmed diagnosis of KOA stage II–III and walking pain ≥4 points on a numerical rating scale (NRS). …”
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Impact of surgical margin status on the survival outcome after surgical resection of gastric cancer: a protocol for systematic review and meta-analysis by Bo Zhang, Yiqiong Yin, Zhaolun Cai, Yuan Yin, Chaoyong Shen, Jinming Huang

“…Therefore, we plan to conduct a systematic review and meta-analysis to quantitatively explore the role of R1 margin on gastric (including oesophagogastric junction) cancer survival after curative intent resection.Methods and analysis The protocol was conducted according to Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guideline. …”
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Comparative analysis of the refractive and functional results of toric intraocular lens with wavefront-shaping mechanism implantation during the surgical treatment of cataracts i... by D.A. Khvan, G.A. Fedyashev

“…To evaluate the effectiveness of toric IOL with a wavefront shaping mechanism implantation in cataract surgical treatment in patients after PKP. Material and methods. This prospective study included 65 patients (65 eyes) who underwent cataract surgery after prevous PKP (the time after removal of corneal sutures averaged 1.4±0.8 years). …”
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RESULTS OF AN OBSERVATIONAL PROSPECTIVE STUDY OF THE EFFICACY AND SAFETY OF BELIMUMAB (BENLYSTA®) IN SYSTEMIC LUPUS ERYTHEMATOSUS IN REAL CLINICAL PRACTICE by E. A. Aseeva, S. K. Soloviev, A. A. Mesnyankina, T. M. Reshetnyak, N. E. Lopatina, S. I. Glukhova, E. L. Nasonov

“…To evaluate the efficacy of belimumab (BLM), a biological agent, that blocks B-lymphocyte-stimulating factor registered for the treatment of active SLE, is an important task of the practice of rheumatology.Objective: to evaluate the efficacy and safety of BLM in patients with high and moderate SLE activity.Subjects and methods. The investigation enrolled 16 patients with a Systemic Lupus Erythematosus Disease Activity Index (SLEDAI-2K) score of 6 to 19, who were positive for antinuclear factor (100%) and had low complement levels and high anti-native DNA antibodies (81%). …”
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Graph theory-based analysis of functional connectivity changes in brain networks underlying cognitive fatigue: An EEG study. by Yabing Lou, Rui Pi, Ruifeng Sun, Jilin Wu, Wei Wang, Ziman Zhu, Tengteng Dai, Weijun Gong

“…Through the application of both global and local graph-theoretical metrics to characterize the topology of brain networks, this study establishes a conceptual framework supporting enhanced detection of cognitive fatigue manifestations while facilitating examination of its neurophysiological substrates.<h4>Methods</h4>The study cohort comprised neurologically intact individuals aged 20-35 years, recruited from Beijing Rehabilitation Hospital, Capital Medical University between February 6 and September 30, 2024 for participation in a cognitive fatigue induction task. …”
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Machine Learning-Based Mortality Risk Prediction Model in Patients with Sepsis by Zhang Y, Li C, Ji Y, Wei B, Guo S, Mei X, Wang J

“…By integrating traditional biomarkers, novel biomarkers, clinical data, and established scoring systems, the model seeks to enhance predictive accuracy and thereby improve clinical outcomes in high-risk patient population.Methods: Conducted at Beijing Chao-Yang Hospital from August 2021 to August 2023, our study included 180 emergency department patients meeting Sepsis 3.0 diagnostic criteria. …”
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The effects of short-term preoperative physical therapy and education on early functional recovery of patients younger than 70 undergoing total hip arthroplasty by Vukomanović Aleksandra, Popović Zoran, Đurović Aleksandar, Krstić Ljiljana

“…The aim of this paper was to investigate the effect of short-term preoperative program of education and physical therapy on patients' early functional recovery immediately after total hip arthroplasty (THA). Methods. This prospective study included 45 patients with hip osteoarthritis scheduled to undergo primary THA and admitted to the Department of Orthopedics of Military Medical Academy. …”
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Global, regional, and national differences in the burden of refraction disorders among children, adolescents, and older adults: current trends and future projections by Qiheng Yuan, Longji Wang, Bianjin Sun, Siwen Chen, Yutong Kang, Yongliang Lou, Meiqin Zheng

“…This study used data from the 2021 Global Burden of Disease (GBD) report to analyze regional differences and trends in the burden of RD among children, adolescents, and the elderly at the national level. Methods GBD 2021 data were used to examine RD burden in these groups, exploring associations with the Socio-demographic Index (SDI) and analyzing inequality trends. …”
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Bibliometric analysis of immunogenic cell death in hepatocellular carcinoma by Jianming Sun, Chun Liu, Dongdong Liu, Xinlian Hu, Shirong Ren, Guoying Jiang, Daizhong Zhang, Shuai Hu, Xiaojing Yuan, Jun Tao

“…Using VOSviewer network visualisation and R-bibliometrix quantitative metrics, we sought to show how scientific output has evolved and to pinpoint research gaps that may guide future investigations. Methods We retrieved 568 publications from the Web of Science Core Collection (2000–2024) using a tailored keyword strategy encompassing “Hepatocellular carcinoma” and “Immunogenic cell death.” …”
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Efficacy of Intraoperative Paracetamol and Nefopam Infusions in Addition to Transversus Abdominis Plane Block in Kidney Transplant Recipients by Jaesik Park, Sun Cheol Park, Min Suk Chae, Sang Hyun Hong, Jung-Woo Shim

“…This retrospective study explored the additional analgesic efficacy of paracetamol and nefopam infusions in living-donor KT recipients who received a transversus abdominis plane (TAP) block. <i>Materials and Methods</i>: Consecutive living-donor KT recipients at our institute between January 2020 and March 2022 were divided into groups that received a TAP block with paracetamol and nefopam infusions (Group TA) or a TAP block without analgesics (Group T) during surgery. …”
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Efficacy and safety of acupuncture in the treatment of Meniere’s disease: a systematic review and meta-analysis by Mingjie Tang, Mingjie Tang, Yinghong Li, Man Lu, Tianchen Zhang, Yanhao Ge, Jie Han, Jiqin Tang, Zhaoming Chen

“…This review aimed to evaluate the efficacy of acupuncture treatment for MD.MethodsEight databases were systematically searched from their inception to June 1, 2024, to identify randomized clinical trials on acupuncture treatment for MD. …”
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Geospatial Trends in Insurance Payor Reimbursements Based on Area Deprivation Index for Total Ankle Arthroplasty across Southwestern Pennsylvania by Garcia Findlay BS, Marfred Umanes Munoz BS, MS, Kenzo M. Cotton BS, Devon Scott, Richard Michael Smith MD, Jarrett D. Cain DPM MSc, Lauren Lewis MD MPH, Macalus V. Hogan MD, MBA

“…Our study analyzes the geospatial trends in medical reimbursement types and TAA utilization across Southwestern Pennsylvania whether a significant association between neighborhood socioeconomic conditions, as measured by the ADI, and reimbursement type exists. Methods: Institutional review board approval was obtained (IRB 20020136). …”
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Quantitative ultra-widefield fluorescein angiography biomarkers in diabetic retinopathy and association with treatment and progression by Iyengar RS, Fleifil S, Aaberg MT, Yu G, Patel TP, Powell C, Tran AK, Paulus YM

“…Wolfe St, Baltimore, MD, 21287, USA, Tel +1 410 955-3518, Email ypaulus1@jh.eduPurpose: To determine if demographic factors and calculated areas of nonperfusion (NP) and neovascularization (NV) on ultra-widefield (UWF) fluorescein angiography (FA) in the eyes of patients with diabetes are associated with treatment with intravitreal injections (IVIs), panretinal photocoagulation (PRP), and diabetic retinopathy (DR) progression.Patients and Methods: This retrospective, cross-sectional study included 363 patients (651 eyes) treated at the University of Michigan Kellogg Eye Center between January 2009 and May 2018. …”
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Apoptosis-Inducing Factor (AIF) content in tumor cell mitochondria from colorectal cancer patients by O. I. Kit, E. M. Frantsiyants, S. A. Ilchenko, V. A. Bandovkina, I. V. Neskubina, A. I. Shikhlyarova, Yu. A. Petrova, A. A. Vereskunova, A. O. Adamyan, E. N. Kolesnikov, G. G. Beloshapkina, A. Yu. Arakelova, U. M. Gaziev, S. V. Sanamyants

“…To investigate the level of protein AIF in the mitochondria of tumor cells and visually unchanged tissues of the colon in male and female patients with colorectal cancer.Materials and methods. …”
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Microvascular flow imaging of fibroids: A prospective pilot study by Marissa Frijlingh, Barbara Stoelinga, Robert A. deLeeuw, Wouter J. K. Hehenkamp, Jos W. R. Twisk, Thierry van denBosch, Lynda J. M. Juffermans, Judith A. F. Huirne

“…The purpose of our study was to determine the reproducibility of MV‐flow imaging and to explore this technique for clinical practice for assessing blood flow in fibroids. Material and Methods Thirty patients with one or multiple fibroids (diameter 1.5–12.0 cm) were prospectively included. …”
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Immediate effects of high-intensity laser therapy for nonspecific neck pain: a double-blind randomized controlled trial by Yuhua Xie, Yuhua Xie, Yingxiu Diao, Dongyu Wu, Manxia Liao, Linrong Liao, Linrong Liao, Linrong Liao

“…ObjectivesThe objective of this research was to assess the immediate effects of high-intensity laser therapy (HILT) on nonspecific neck pain (NNP) by evaluating outcome measures such as pain intensity, cervical active range of motion (ROM), stiffness of neck muscles, and functional disability.MethodsThis clinical trial, which was conducted in a double-blind and randomized manner, involved patients diagnosed with NNP who were allocated either to either a HILT group (HILT + exercise) or a placebo group (placebo-laser therapy + exercise). …”
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