Cryotherapy for Rehabilitation After Total Knee Arthroplasty: A Comprehensive Systematic Review and Meta‐Analysis by Zhimin Liang, Zichuan Ding, Duan Wang, Yuchen Guo, Ling Zhu, Zeyu Luo, Lingli Li

“…The aim of this systematic review and meta‐analysis was to investigate (1) whether cryotherapy is able to promote the rehabilitation of patients undergoing TKA and (2) whether continuous cold flow device has superior results than cold pack in cryotherapy. Methods A comprehensive trial searching was performed in the PubMed, Embase, Cochrane Library, and Google Scholar electronic databases in May, 2024. …”
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Observation of the clinical efficacy of intersphincteric ligation combined with traction and catheterization in the treatment of anal abscess by Xu Shumin, Wang Qunbo, Jiang Weidong, Dong Qingjun, Wang Chen

“…[Objectives] To observe the clinical efficacy of intersphincteric ligation combined with traction and catheterization in the treatment of anal abscess. [Methods] Total of eighty patients with anal abscess diagnosed in the Department of Anorectal Surgery, Longhua Hospital, Shanghai Traditional Chinese Medicine University from December 2019 to June 2021 were randomly divided into treatment group (n＝40, treated with intersphincteric ligation combined with traction and catheterization) and control group (n＝40, treated with incision and drainage). …”
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Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population by Charumathi Sabanayagam, Ching-Yu Cheng, Tien-Yin Wong, Wan Ting Tay, Jonathan Yap, Daniel Ting, Kamalesh Anbalakan, Carol Yim Cheung, Khung Keong Yeo

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Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a tr... by Nikhil Harikrishnan, Ravi Kumar Nesamani, S. Aysha Sherin, Kavitha Sanjeev, Mahalaxmi Sekar

“…Pain levels were recorded using the Heft Parker Visual Analogue Scale (HP-VAS) at various intervals. …”
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Attitudes toward the adoption of eHealth amongst healthcare professionals in trauma surgery – the new digital normal? by Jelle Friso Spierings, Gijs Johan Antoon Willinge, Bas Anne Twigt, Sjoerd Repping, Marike Cornelia Kokke, Ruben van Veen, Detlef van der Velde

“…As this is currently lacking, this study explores the use of eHealth in daily practice, opportunities of eHealth, implementation barriers, and desired functions and features amongst healthcare professionals working in Dutch orthopedic surgery and traumatology. Methods A cross-sectional, web-based survey among the 605 members of the Dutch Society of Trauma Surgery and related healthcare professionals on the attitudes towards eHealth in daily practice was performed between November 4, 2021, and March 31, 2022. …”
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A Non-Surgical Wearable Option for Bone Conduction Hearing Implants: A Comparative Study with Conventional Bone Conduction Hearing Aids Mounted on Eyeglasses by Federica Di Berardino, Giovanni Ciavarro, Giulia Fumagalli, Claudia Albanese, Enrico Pasanisi, Diego Zanetti, Vincenzo Vincenti

“…This study aimed to compare the audiological benefits of a non-implantable wearable option for a bone conduction (BC) implant mounted on an arch (SoundArc) to those of traditional BC hearing aids (HAs) mounted on eyeglasses (BCHAs) in patients with moderate to severe conductive or mixed hearing loss. Methods: A preliminary cross-sectional observational prospective cohort study was conducted in the Tertiary Audiological Department, University Hospital. …”
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Development of policy research-evidence organizer and public health-policy evaluation tool (prophet): a computing paradigm for promoting evidence-informed policymaking in Nigeria by Kingsley Otubo Igboji, Chigozie Jesse Uneke, Fergus U. Onu, Onyedikachi Chukwu

“…It strategically evaluates and assess level of evidence content, and predict implementation prospects of health policy documents.</p><p><strong><em>Methods: </em></strong>its development process adopted object-oriented methodology for structural analysis and design specifications. …”
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Effect of enhanced recovery after surgery (ERAS) protocol on maternal and fetal outcomes following elective cesarean section: an observational trial by Miray Gözde Özdemir, Berrin Gunaydin, Merih Bayram, İbrahim Murat Hirfanoglu

“…Abstract Background We aimed to investigate the maternal, fetal, and neonatal outcomes in parturients scheduled to undergo cesarean section (CS) receiving either standard care or enhanced recovery after surgery (ERAS) protocol. Methods After approval of ethics committee (Gazi University Protocol Record Decision no: 502/31.05.2021) and registry to clinical trials (NCT06753058, Date 12/30/2024) 450 ASA II-III parturients at ≥ 18 years of age scheduled for elective CS under spinal anesthesia using bupivacaine plus opioids were included (n = 150, ERAS group and n = 300, control group). …”
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Application of comprehensive geriatric assessment in health management of older patients with grade Ⅲ to Ⅳ mixed hemorrhoids undergoing surgery by Jiang Zhiyuan, Zhong Shibiao, Tang Li, Li Zhen

“…[Objectives] To investigate the application of comprehensive geriatric assessment (CGA) in the health management of older patients with grade Ⅲ to Ⅳmixed hemorrhoids undergoing surgery. [Methods] Sixty older patients with grade Ⅲ to Ⅳ mixed hemorrhoids treated at the Department of Anorectal Surgery at our hospital between January and October 2021 were recruited and randomly assigned to the control group (n=30) and the treatment group (n=30). …”
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The impact of pyrethroid resistance on the efficacy of insecticide-treated bed nets against African anopheline mosquitoes: systematic review and meta-analysis. by Clare Strode, Sarah Donegan, Paul Garner, Ahmad Ali Enayati, Janet Hemingway

“…We therefore assessed the evidence that resistance is attenuating the effect of ITNs on entomological outcomes.<h4>Methods and findings</h4>We included laboratory and field studies of African malaria vectors that measured resistance at the time of the study and used World Health Organization-recommended impregnation regimens. …”
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Evaluation of the Effects of Retro-Cavity Preconditioning with or Without Ethylenediaminetetraacetic Acid on Root Surface pH and Dislodgement Resistance of NeoMTA2 and Mineral Trio... by Sedigheh Khedmat, Seyyed Ali Abaee, Hadi Assadian, Antonio Signore, Stefano Benedicenti

“…<b>Background:</b> The aim of this study was to investigate the effects of retro-cavity preconditioning with or without 17% ethylenediaminetetraacetic acid (EDTA) solution on root surface pH as well as dislodgement resistance of NeoMTA2 and MTA Flow retro-fills. <b>Methods:</b> Forty-eight single-rooted human incisors were selected. …”
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Prokineticin 2 neurons form diverse subpopulations in the suprachiasmatic nucleus and rely on VPAC2-signaling for diurnal rhythmicity by Ida Stangerup, Ida Stangerup, Birgitte Georg, Jens Hannibal, Jens Hannibal

“…Hence, the aim of this study was to characterize PK2 neurons in relations to light-responsiveness and neuropeptidergic markers of the core-shell division.MethodsDouble and triple immunohistochemistry of PK2 together with phenotypical neuropeptide/receptor markers of the core-shell division was performed at zeitgeber time (ZT) 8. …”
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CT radiation dose reduction with tin filter for localisation/characterisation level image quality in PET-CT: a phantom study by Natalie Anne Bebbington, Lone Lange Østergård, Kenneth Boye Christensen, Paw Christian Holdgaard

“…The aim was to determine the level of CT dose reduction permitted with the tin filter in PET-CT, for comparable image quality to the clinical reference standard (CRS) L/C CT images acquired with standard filtration. Materials and methods A whole-body CT phantom was scanned with standard filtration in CRS protocols, using 120 kV with 20mAs-ref for bone L/C (used in 18F-Sodium Fluoride (NaF) PET-CT) and 40mAs-ref for soft tissue L/C (used in 18F-Fluorodeoxyglucose (FDG) PET-CT), followed by tin filter scans at 100 kV (Sn100kV) and 140 kV (Sn140kV) with a range of mAs settings. …”
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Prevalence and characteristics of transthyretin amyloid cardiomyopathy in hypertrophic cardiomyopathy by Pablo Garcia‐Pavia, Thibaud Damy, Nicolas Piriou, Roberto Barriales‐Villa, Francesco Cappelli, Catherine Bahus, Carmen Munteanu, Denis Keohane, Pablo Mallaina, Perry Elliott, the TTRACK investigators

“…We examined the prevalence and characteristics of transthyretin amyloid cardiomyopathy in older patients with hypertrophic cardiomyopathy of unascertained aetiology. Methods and results TTRACK was a multicentre, non‐interventional, cross‐sectional epidemiologic study funded by Pfizer and conducted in 20 hospitals and medical centres in 11 countries (NCT03842163). …”
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A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…This study focuses on the efficacy and safety of combining Onabotulinumtoxin A (OnaBoNT-A) and hyaluronic acid filler (HA filler) to target enlarged facial pores in Asians. Materials and Methods: This study aimed to compare the efficacy and safety of OnaBoNT-A monotherapy in combination with HA filler for the treatment of enlarged facial pores. …”
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Benchmarking of Large Language Models for the Dental Admission Test by Yu Hou, Jay Patel, Liya Dai, Emily Zhang, Yang Liu, Zaifu Zhan, Pooja Gangwani, Rui Zhang

“…Understanding the capabilities and limitations of these models is critical for determining their suitability in test preparation. Methods: This study evaluated the ability of 16 LLMs, including general-purpose models (e.g., GPT-3.5, GPT-4, GPT-4o, GPT-o1, Google’s Bard, mistral-large, and Claude), domain-specific fine-tuned models (e.g., DentalGPT, MedGPT, and BioGPT), and open-source models (e.g., Llama2-7B, Llama2-13B, Llama2-70B, Llama3-8B, and Llama3-70B), to answer questions from a sample DAT. …”
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The efficacy and prognosis analysis of short-term spinal cord stimulation in the treatment of zoster-associated pain: a retrospective study by Xiang Wang, Yimin Gao, Jing Yu, Wenqu Yang, Wenjing Zhang, Jianzhong Huo

“…However, in the existing literature, there is a paucity of comprehensive reports elaborating on the risk factors that impact its treatment efficacy.ObjectiveThis study aimed to evaluate the clinical efficacy of stSCS in the treatment of ZAP, and to analyze the risk factors that influence the treatment efficacy.MethodsClinical data of patients diagnosed with ZAP and who underwent stSCS surgery in the Pain Department of Shanxi Bethune Hospital from January 2020 to December 2023 were collected. …”
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Virtual Reality for the Prevention and Cessation of Nicotine Vaping in Youths: Protocol for a Randomized Controlled Trial by Belinda Borrelli, Daniel Weinstein, Romano Endrighi, Nikki Ling, Kathleen Koval, Lisa M Quintiliani, Kaitlyn Konieczny

“…ObjectiveThis randomized controlled trial aimed to evaluate the feasibility and preliminary efficacy of a virtual reality (VR) intervention for teens that targets both determinants of vaping (eg, mood and stress) and vaping prevention and cessation skills. MethodsThe participants are 150 students attending 1 of 2 racially and ethnically diverse Boston-area high schools. …”
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Examining Demographic, Geographic, and Temporal Patterns of Melanoma Incidence in Texas From 2000 to 2018: Retrospective Study by Kehe Zhang, Madison M Taylor, Jocelyn Hunyadi, Hung Q Doan, Adewole S Adamson, Paige Miller, Kelly C Nelson, Cici Bauer

“…ObjectiveThis study aims to analyze temporal and spatial trends in melanoma incidence by stage at diagnosis (overall, early, and late) in Texas from 2000 to 2018, focusing on demographic and geographic variations to identify high-risk populations and regions for targeted prevention efforts. MethodsWe used melanoma incidence data from all 254 Texas counties from the Texas Cancer Registry (TCR) from 2000 to 2018, aggregated by county and year. …”
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Return to sport and patient reported outcomes in athletes participating in martial arts after anterior cruciate ligament reconstruction at mean follow‐up of 12 years by Yunseo Linda Park, Anja M. Wackerle, Brooke Collins, Ehab M. Nazzal, Joseph D. Giusto, Matthew Kolevar, James J. Irrgang, Jonathan D. Hughes, Volker Musahl

“…Abstract Purpose This study aims to assess anterior cruciate ligament reconstruction (ACLR) outcomes and return to pre‐injury sports (RTPS) characteristics in athletes participating in martial arts. Methods Martial arts athletes over the age of 14 years who underwent primary ACLR with a minimum 1‐year follow‐up were eligible for this study. …”
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