Impact of preoperative intraocular pressure on corneal endothelial cell loss after phacoemulsification in acute primary angle-closure glaucoma with cataracts by Jiaqi Shen, Xin Liu, Xin Liu, Mingyue Lin, Yuting Shao, Guozhen Niu, Shen Qu, Yunli Niu, Qi Zhou, Li Zhang, Yanlong Bi, Yanlong Bi

“…PurposeThis study aimed to assess corneal endothelial cell loss (ECL) following phacoemulsification and intraocular lens implantation (Phaco+IOL) in eyes with acute primary angle-closure glaucoma (APACG) and cataracts under different preoperative intraocular pressure (IOP) levels.MethodsThis non-randomized controlled trial included 75 eyes from 75 patients with APACG and cataracts who underwent Phaco+IOL. …”
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Preoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study by Maximilian Friedrich, Hyeck-Soo Son, Jasper Lind, Maximilian Hammer, Lizaveta Chychko, Timur Mert Yildirim, Gerd Uwe Auffarth, Victor Aristide Augustin

“…The goal of this study was to compare the surgical outcomes after DMEK in FECD patients with subclinical corneal edema and clinical corneal edema to test the hypothesis of whether performing surgery in subclinical corneal edema stages achieves better surgical outcomes. Methods In this prospective, observational, single-institution cohort study, 106 pseudophakic eyes of 85 patients with FECD were divided into two groups depending on the presence of preoperative subclinical and clinical corneal edema. …”
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Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): study protocol... by Timothy L. Jackson, Catey Bunce, Riti Desai, Jost Hillenkamp, Chan Ning Lee, Noemi Lois, Tunde Peto, Barnaby C. Reeves, David H. Steel, Rhiannon T. Edwards, Jan C. van Meurs, Hatem Wafa, Yanzhong Wang

“…No large, published, randomised controlled trials have compared these management options. Methods TIGER is a phase 3, pan-European, two-group, active-control, observer-masked, superiority, randomised controlled surgical trial. …”
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Optical Coherence Tomography Angiography Changes in Diabetic Macular Ischemia after Systemic Normobaric Oxygen Therapy by Diba Idani, Seyed Mohammadjavad Mashhadi, Hamze Babaei, Farideh Sharifipour, Ramin Nourinia, Bahareh Kheiri, Arezoo Miraftabi

“… Purpose: To evaluate vascular changes on optical coherence tomography angiography (OCTA) in patients with diabetic macular ischemia (DMI) after systemic normobaric oxygen (NBO) therapy. Methods: This before–after interventional study included 26 eyes of 26 patients with DMI. …”
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Integrating Transcriptomic and Proteomic Data: IL‐27B as a Key Protein in the Development of Septic Cardiomyopathy—A Retrospective Study by Yifeng Mao, Qingqing Chen, Yongpo Jiang, Xijiang Zhang, Qin Si, Panpan Xu, Zhongheng Zhang, Cheng Zheng, Ronghai Lin

“…In this study, transcriptomic and proteomic analyzes of serum samples from sepsis patients were conducted to uncover the underlying pathological mechanisms and identify potential therapeutic targets for SCM. Methods This retrospective, dual‐center study investigated the progression of sepsis to SCM in patients admitted to intensive care units. …”
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AI-driven MRI analysis reveals brain atrophy patterns in benign relapsing-remitting multiple sclerosis by M. Niiranen, M. Niiranen, P. Bendel, P. Bendel, J. Koikkalainen, J. Lötjönen, T. Selander, E. Solje, E. Solje, P. Hartikainen, S. Simula, R. Vanninen, R. Vanninen, A. M. Portaankorva

“…In this study, we aimed to investigate the brain atrophy patterns related to benign relapsing-remitting MS (BRRMS), particularly regarding location and extent.MethodsWe analyzed global and regional gray matter (GM) and white matter (WM) volumes, WM lesion load, corpus callosum index (CCI) and corpus callosum area (CCA) in well-defined benign relapsing-remitting MS patients (BRRMS, n = 35) compared to healthy controls (HC, n = 35). …”
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Impact of IYCF practices, as measured by national nutrition surveys from 2018 to 2022, on stunting and under-5 survival in Burkina Faso: a LiST analysis by Natacha Kere, Ella W. R. Compaore, Ella W. R. Compaore, Youssouf Keita, Daniel S. Ouedraogo, Souleymane Tirogo, Estelle A. Bambara, Z. Thierry Coulibaly, Mamoudou H. Dicko

“…This study aims to assess the impact of these interventions on the nutritional status of children aged 0–5 years between 2018 and 2022.MethodsThis study is a modeling of the impact of changes in the coverage of interventions with known effect sizes, using the LiST (Lives Saved Tool). …”
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Comparative efficacy and safety of anti-HGF/MET pathway agents plus chemotherapy versus chemotherapy alone as first-line treatment in advanced gastric cancer: a protocol for a syst... by Chunyu Liu, Bo Zhang, Zhiyuan Jiang, Zhaolun Cai, Yuan Yin, Chaoyong Shen, Qin Ma, Xiaonan Yin, Chen Chang, Zhou Zhao, Mingchun Mu

“…Statistical heterogeneity will be assessed by visual inspection of forest plots and measured using the I2 statistics. …”
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Attention Performance and Altered Amplitude of Low-frequency Fluctuations in the Attention Network of Patients with MCI: A Resting-state Functional MRI Study by Jia Luo, Yi Zeng, Yuwei Ye, Yiping Xiao, Qiurong Xie, Jijing Zhang, Weilin Cai, Huanyun Xu, Shengxiang Liang, Jia Huang

“…Background: This study aimed to explore attention alteration in mild cognitive impairment (MCI) patients and their association with abnormalities of autonomic brain activity within the attention network to reveal the neuroimaging basis behind these changes. Methods: A total of 25 MCI patients and 31 normal controls (NCs) were recruited for the study. …”
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Clinical observation of the effectiveness of radiofrequency ablation on improving internal hemorrhoidal bleeding symptom by Zhu Zhihong, Cao Mohan, Wang Zhimin, Li Tao, Wu Guoliang, Wu Xianhai, Yang Tengteng

“…[Objectives] To investigate the clinical effectiveness of radiofrequency ablation (RFA) on improving internal hemorrhoidal bleeding symptom. [Methods] A total of 160 patients with internal hemorrhoidal bleeding symptom treated at Shandong Second Provincial General Hospital and The First Affiliated Hospital of Shandong First Medical University from June 2022 to March 2023 were enrolled. …”
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Telemedicine for under-resourced patients with systemic lupus erythematosus: a qualitative study exploring the views and experiences of patients and their healthcare team by Savannah Bowman, Sandeep K. Agarwal, Keshia C. Ferguson, Maryjo J. Maliekel, Maria A. Lopez-Olivo, Maria E. Suarez-Almazor, Maria I. Danila, Maria I. Danila, Jinoos Yazdany, Sebastian Bruera

“…Themes and subthemes were identified and visualized.ResultsFourteen interviews were conducted. …”
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Quality of Life and Well‐Being in Adults With Fontan Physiology: Findings From the Australian and New Zealand Fontan Registry Quality of Life Study by Kate H. Marshall, Yves d'Udekem, David S. Winlaw, Diana Zannino, David S. Celermajer, Robert Justo, Ajay Iyengar, Rachael Cordina, Gary F. Sholler, Susan R. Woolfenden, Nadine A. Kasparian

“…Background To characterize global and health‐related quality of life (QOL) among adults with Fontan physiology enrolled in the Australian and New Zealand Fontan Registry (ANZFR), and identify sociodemographic, clinical, psychological, and relational factors associated with outcomes. Methods and Results Using a cross‐sectional survey design, 66 adults with Fontan physiology (58% women; mean age, 29.6±7.7 years; range, 18–50 years) completed validated self‐report measures. …”
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Bioactive natural alkaloid 6−Methoxydihydrosanguinarine exerts anti−tumor effects in hepatocellular carcinoma cells via ferroptosis by Linfen Han, Linfen Han, Chengchang Gao, Xiaorui Jin, Yingping Li, Liangjie Chen, Donglin Li, Qinqin Deng, Xueli Bian, Xueli Bian

“…Natural active compounds have great potential in cancer treatment.MethodsThe impact of 6-ME on the cell viability of HCC cells was assessed using the Cell Counting Kit-8 (CCK‐8) assay and colony formation assay. …”
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Investigating the Effect of Reducing the Signs and Symptoms of Lid Wiper Epitheliopathy in Patients With Dry Eye Disease With Perfluorohexyloctane by Chris Lievens, OD, MS, PhD, FNAP, FAAO, Andrew D. Pucker, OD, PhD, FAAO, Quentin Franklin, BS, Stephen M. Montaquila, OD, FAAO, Brad Giedd, OD, MS, FAAO, Gina Wesley, OD, MS, FAAO, Morgan Bromley, PhD, Zackarias Coker, MS, John Meyers, MS, Marta Vianya-Estopa, PhD

“…Objective: To examine the potential of using perfluorohexyloctane for reducing the signs and symptoms of lid wiper epitheliopathy (LWE). Methods: Data were collected at 4 visits spanning 2 months. …”
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Displacement-related stressors in a Sudanese war-affected community; identifying the impact of war exposure and ongoing stressors on trauma symptom severity: a national multi-cente... by Lina Hemmeda, Alaa S. Ahmed, Gasm Alseed Abdelmonim Gasm Alseed Fadlalmoula, Doaa Rabeie Hassan, Mohammed Haydar Awad, Gotof Salim, Abeer Osman Mukhtar Elabid, Alaa Azhary mohammed Ali, Asmaa O. Algasim, Ethar Hamad, Fatima Afif, Fatima Mustafa, Maha Rhamttallah, Mai Fathi Awadalla Alsedig, Miada Ali Mohammed Taha, Muram Ahmed Sayed Khaleel, Nazik Abdalla Nourin, Roaa Salah Eltaheir Mohieldin, Sara Ali, Shimaa Suliman, Khabab Abbasher Hussien Mohamed Ahmed

“…Our study aimed to understand the relationship between displacement-related stressors and trauma symptom severity. Methods This was an observational, multi-center cross-sectional study conducted across seven conflict-free states in Sudan. …”
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Gallium Resistance in <i>Staphylococcus aureus</i>: Polymorphisms and Morphology Impacting Growth in Metals, Antibiotics and Polyfluorinated Compounds by Akamu Ewunkem, Felicia Simpson, David Holland, Tatyana Bowers, Ariyon Bailey, Ja’nyah Gore, Uchenna Iloghalu, Vera Williams, Sarah Adjei-Fremah, Larisa Kiki, Brittany Justice

“…This study utilized experimental evolution to test the evolvability of gallium resistance in <i>Staphylococcus aureus</i> and resistance traits potentially correlated with metals, antibiotics and polyfluorinated compounds, as well as its genomics foundations. Methods: Whole-genome sequencing was utilized to reveal functional networks of mutations associated with gallium resistance. …”
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Anti-Fibrotic Effect of Tacrolimus on Preventing Adhesion after Achilles Tendon Surgery in a Murine Model by Seyedeh Elnaz Nazari, Elnaz Ghorbani, Abdulridha Mohammed Al-Asady, Sayyed-Hadi Sayyed-Hosseinian, Farzad Rahmani, Ehsan Vahedi, Amir Avan, Mohammad-Mostafa Askarnia-Faal, Hamideh Naimi, Majid Khazaei, Seyed Mahdi Hassanian

“…This study aims to evaluate the repurposed potential of the immunosuppressive approved drug, tacrolimus, in decreasing adhesion band formation post-Achilles tendon surgeries in an animal model.Methods: Rats were randomly assigned to four groups: control, sham with surgical intervention but no adhesion, positive control group with surgical transection and adhesion received no treatment, tacrolimus group was the same as the positive control group except that rats were treated with 2 mg/Kg/day tacrolimus orally for 21 days. …”
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Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis by Wim Wuyts, Joseph Jacob, Patrick Verschueren, Veerle Taelman, Barbara Neerinckx, Heleen Cypers, Alexandros Kalkanis, Nico De Crem, Marie Vermant, Tinne Goos, Emanuela Elsa Cortesi, Tine Follet, Stefan Gogaert, Nathalie Veyt, Laurens J De Sadeleer

“…We assessed the role of symptoms and lung ultrasound (LUS) as potential screening tools.Methods 116 adult patients with RA presenting to the rheumatology outpatient clinic underwent high-resolution CT (HRCT) scans, pulmonary function tests, LUS (72 zones) and completed a Visual Analogue Scale (VAS) for cough and modified Medical Research Council dyspnoea scale (mMRC). …”
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Preliminary results of the EPIDIA4Kids study on brain function in children: multidimensional ADHD-related symptomatology screening using multimodality biometry by Yanice Guigou, Alexandre Hennequin, Théo Marchand, Théo Marchand, Mouna Chebli, Lucie Isoline Pisella, Pascal Staccini, Pascal Staccini, Vanessa Douet Vannucci, Vanessa Douet Vannucci

“…Currently, early diagnosis is constrained by clinical complexity and limited resources of professionals to conduct evaluations. Scalable methods for ADHD screening are thus needed. Recently, digital epidemiology and biometry, such as the visual, emotional, or digit pathway, have examined brain dysfunction in ADHD individuals. …”
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Histological Grade, Tumor Breadth, and Hypertension Predict Early Recurrence in Pediatric Sarcoma: A LASSO-Regularized Micro-Cohort Study by Alexander Fiedler, Mehran Dadras, Marius Drysch, Sonja Verena Schmidt, Flemming Puscz, Felix Reinkemeier, Marcus Lehnhardt, Christoph Wallner

“…This exploratory study aimed to identify clinical features associated with first tumor recurrence using a machine learning approach tailored to low-event settings. <b>Methods</b>: We conducted a retrospective, single-center cohort study of 23 pediatric patients with histologically confirmed sarcoma. …”
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