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  1. 29441

    Efficacy and Survival Analysis of Radiotherapy for Internal Mammary Lymph Nodes After Modified Radical Mastectomy for T1-3N3M0 the Lateral Quadrant Breast Cancer by Han X, Jiang D, Zhu C, Li D, Yin H

    Published 2024-11-01
    “…Xiumei Han,1,* Die Jiang,1,* Chaomang Zhu,2,* Duojie Li,1 Hongmei Yin1 1Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China; 2Anhui Provincial Key Laboratory of Tumor Evolution and Intelligent Diagnosis and Treatment, Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongmei Yin, Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China, Tel/Fax +86 182 2655 8221, Email yhm062573@163.comPurpose: This study aimed to investigate the efficacy and survival analysis of internal mammary lymph nodes (IMLNI) radiotherapy after modified radical mastectomy for T1-3N3M0 The lateral quadrant breast cancer.Materials and Methods: A total of 124 patients who underwent adjuvant radiotherapy after modified radical mastectomy for breast cancer in the First Affiliated Hospital of Bengbu Medical University were included. …”
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  2. 29442

    PD(L)1 Inhibitors Plus Lenvatinib Vs Atezolizumab Plus Bevacizumab Combined With HAIC for Unresectable HCC: A Propensity Score Matching Study by He Z, Chen H, Liang C, Tang X, Jiang L, Xie F, Liu Q, Zheng Y

    Published 2025-01-01
    “…Zhaoqian He,1– 3,* Hua Chen,1– 3,* Chen Liang,1– 3,* Xiang Tang,1– 3 Lingmin Jiang,1– 3 Feihu Xie,1– 3 Qi Liu,1– 3 Yun Zheng1– 3 1Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 2Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 3Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yun Zheng; Qi Liu, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, People’s Republic of China, Email zhengyun@sysucc.org.cn; liuqi9@sysucc.org.cnPurpose: To compare the clinical outcomes of different systemic therapies, specifically PD(L)1 inhibitors plus Lenvatinib versus Atezolizumab plus Bevacizumab, when combined with hepatic arterial infusion chemotherapy (HAIC) based on the FOLFOX regimen (oxaliplatin, fluorouracil, and leucovorin) as first line treatment for unresectable hepatocellular carcinoma.Patients and Methods: This real-world retrospective study enrolled 294 patients with unresectable HCC. …”
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  3. 29443

    Efficacy of Transcutaneous Electrical Acupoint Stimulation Applied During the Post-Anesthesia Recovery Period in Improving Postoperative Recovery Quality After Gynecological Laparo... by Zhou Z, Yang X, Shi M, Huang L, Wu D, Yang H, Zhang X

    Published 2025-07-01
    “…This study investigated the impact of TEAS during the post-anesthesia recovery period on postoperative recovery quality in patients undergoing laparoscopic gynecological surgery.Patients and Methods: In this single-center, randomized, double-blinded, sham-controlled trial, 100 patients undergoing elective gynecological laparoscopic surgery were randomly allocated to receive either TEAS or sham stimulation at bilateral Hegu (LI4), Neiguan (PC6), Zusanli (ST36), and Sanyinjiao (SP6) acupoints for 30 minutes during the post-anesthesia recovery period in the post-anesthesia care unit (PACU). …”
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  4. 29444

    Comparative effects of Zumba and Yoga on stress, body satisfaction, and self-esteem in working women: a randomized control trial by Noortje Anita Kumaat, Afif Rusdiawan, Procopio B. Dafun JR., Heri Wahyudi, Popy Elisano Arfanda, Fransisca Januarumi Marhaendra Wijaya, Himawan Wismanadi, Ary Artanty

    Published 2025-06-01
    “…This study aimed to compare the effects of Zumba and yoga on stress, body satisfaction, and self-esteem in working women. Material and Methods. A total of 159 moderately stressed working women (ages 20 to 50) were randomly assigned to one of three groups: yoga (n = 53), Zumba (n = 53), or control (wellness education, n = 53). …”
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  5. 29445

    Incomplete Thermal Ablation-Induced FOXP4-Mediated Promotion of Malignant Progression in Liver Cancer via NDST2 by Wan W, Pan Y, Pang J, Bai X, Li L, Kang T, Chen J, Wen R, Wen D, Yang H, He Y

    Published 2024-10-01
    “…We investigated the mechanism by which Forkhead box P4 (FOXP4) promotes the malignant transformation of residual HCC cells through N-deacetylase and N-sulfotransferase 2 (NDST2) after incomplete thermal ablation.Methods: The clinical significance of FOXP4 and NDST2 in HCC was evaluated using big data analysis. …”
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  6. 29446
  7. 29447

    PRECIS-2 used as an implementation science tool for global environmental health: A cross-sectional evaluation of the Ecolectivos study protocol to reduce burning of household plast... by Lisa M Thompson, Annalyse Ferguson, Hina Raheel, Amy E Lovvorn, Mayari Hengstermann-Artiga, Maria Renee Lopez, Melinda Higgins, Eri Saikawa, Margaret A Handley

    Published 2024-01-01
    “…Ecolectivos is an implementation science study, using a village-level cluster randomized controlled trial design, to assess a behavioral intervention to reduce household plastic waste burning in rural Guatemala.<h4>Methods</h4>We invited 60 researchers to participate in an online survey between February 2022 and January 2023. …”
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  8. 29448

    Changing Trends in the Mental Health Status of Healthcare Workers at COVID-19 Wards Three Years After the COVID-19 Pandemic Outbreak in Saudi Arabia by Alharbi SH, Almoajel AM, Tharkar S, Alharbi AH, Almutairi K, Alzaidi HA, Kattan BF

    Published 2025-05-01
    “…Sami Hamoud Alharbi,1,&amp;ast; Alia Mohammed Almoajel,1,&amp;ast; Shabana Tharkar,1 Abdullah Hamoud Alharbi,2 Khalid Almutairi,1 Hanan Abdullah Alzaidi,1 Basmah Faisal Kattan1 1Department of Community Health Science, College of Applied Medical Science, King Saud University, Riyadh, Saudi Arabia; 2Ministry of Health, Riyadh, Saudi Arabia&amp;ast;These authors contributed equally to this workCorrespondence: Khalid Almutairi, Department of Community Health Science, College of Applied Medical Sciences, King Saud University, Riyadh, 12372, Saudi Arabia, Email kalmutairim@ksu.edu.saBackground: The current study aimed to investigate the severity of anxiety and depression symptoms among the healthcare workers of COVID-19 wards three years after the pandemic outbreak in Saudi Arabia.Methods: An online cross-sectional survey was conducted during the fourth quarter of 2022 and early 2023 at the COVID-19 wards of public primary healthcare hospitals of the AlQassim region of Saudi Arabia. …”
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  9. 29449

    Altered Immune Cell Profiles in the Follicular Fluid of Patients with Poor Ovarian Response According to the POSEIDON Criteria by Zhou L, Zhao S, Luo J, Rao M, Yang S, Wang H, Tang L

    Published 2024-12-01
    “…Ling Zhou,1 Shuhua Zhao,1 Jiahuan Luo,1 Meng Rao,1 Shuangjuan Yang,2 Huawei Wang,1 Li Tang1 1Department of Reproduction and Genetics, The First Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of China; 2The Core Technology Facility of Kunming Institute of Zoology (KIZ), Chinese Academy of Sciences (CAS), Kunming, People’s Republic of ChinaCorrespondence: Li Tang, Department of Reproduction and Genetics, The First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Wuhua District, Kunming, People’s Republic of China, Email tanglikm@163.comObjective: This study aims to investigate alterations in immune cell counts within preovulatory follicles of patients with poor ovarian response (POR) during assisted reproductive technology (ART), classified according to the POSEIDON criteria.Methods: This single-centre cross-sectional study included 543 women undergoing IVF/ICSI treatment, selected based on specific inclusion and exclusion criteria: 292 with normal ovarian response and 251 with poor response. …”
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  10. 29450

    Combination Fractional Carbon Dioxide Laser Treatment and Bone Marrow Mesenchymal Stem Cell Therapy Enhances the Treatment of Skin Photoaging in a Murine Model System by Li L, He Z, Yu C, Zhang C, Yu Y, Li Y, Xu X

    Published 2025-01-01
    “…Li Li,1– 3,&ast; Zeyu He,3– 5,&ast; Chengqian Yu,3– 5 Chao Zhang,3– 5 Yanqiu Yu,6 Yuanhong Li,3– 5 Xuegang Xu3– 5 1ShanXi Medical University, Taiyuan, People’s Republic of China; 2Department of Dermatology, The First Hospital of ShanXi Medical University, Taiyuan, 030001, People’s Republic of China; 3Department of Dermatology, The First Hospital of China Medical University, Shenyang, 030001, People’s Republic of China; 4Key Laboratory of Immunodermatology (China Medical University), Ministry of Education, Shenyang, 110001, People’s Republic of China; 5NHC Key Laboratory of Immunodermatology (China Medical University), Shenyang, 110001, People’s Republic of China; 6Department of Pathophysiology, College of Basic Medical Science, China Medical University, Shenyang, 110122, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xuegang Xu, Department of Dermatology, The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning Province, 110001, People’s Republic of China, Email xuxuegang2749290@163.com Li Li, Department of Dermatology, The First Hospital of ShanXi Medical University, No. 85 South Jiefang Road, Yingze District, Taiyuan, Shanxi Province, 030001, People’s Republic of China, Email lilizaimu0807@163.comBackground: Fractional carbon dioxide lasers and bone marrow mesenchymal stem cells (BMSCs) are commonly employed in the treatment of skin photoaging.Objective: This study was developed to explore the effects of combination carbon dioxide laser treatment and BMSC injection on skin photoaging and the underlying molecular mechanisms.Methods & Materials: In total, 24 mice with experimentally photoaged skin were separated into control, carbon dioxide fractional laser treatment, combination therapy, and BMSC injection groups. …”
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  11. 29451

    Comparison of Biometric Measurements and IOL Power Calculation Between a Swept-Source OCT and an Optical Low-Coherence Reflectometry Biometer by Romero D, Monera CE, Cooke D, Alio JL, Tarazona C, Martínez-Toldos JJ

    Published 2025-06-01
    “…Joseph, MI, USA; 3VISSUM Ophthalmological Institute of Alicante, Alicante, SpainCorrespondence: Daniel Romero, Department of Ophthalmology, General University Hospital of Elche, Carrer de la Almazara 11, Elche, Alicante, CP 03203, Spain, Email drv.romero@gmail.comPurpose: To evaluate the comparability of biometric measurements obtained using the swept-source optical coherence tomography (SS-OCT) biometer (Anterion) and the optical low-coherence reflectometry (OLCR) biometer (Lenstar LS900).Methods: This observational study included 150 cataract patients undergoing preoperative biometry at the General University Hospital of Elche. …”
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  12. 29452

    Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway by Li Q, Zheng JW, Wang ZY, Liao SP, Zhu L, Wang X, Wan LH

    Published 2025-01-01
    “…This study was conducted to explore the protective effects and mechanism of rosmarinic acid (RA) against ERS in endotoxin-induced cognitive dysfunction in mice and neuronal injury in cells.Methods: The efficacy of RA was evaluated using an endotoxin-induced cognitive dysfunction mice model and an in vitro neuronal injury model. …”
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  13. 29453

    Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study by Wang Q, Yin Y, Liu W, Li L, Wang Z, Tian Y, Fan J

    Published 2025-01-01
    “…Qing Wang,1,&ast; Yishan Yin,2,&ast; Wei Liu,3,&ast; Lingyu Li,1 Zhen Wang,1 Yue Tian,1 Jing Fan1 1Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 2Department of Orthopedics, The Armed Police Forces Hospital of Shandong, Jinan, Shandong, 250000, People’s Republic of China; 3Department of Emergency Critical Care Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jing Fan, Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email sddzfanjing@163.comBackground: This study investigates the correlation between the weight-adjusted waist index (WWI) and cognitive performance in the senior American population, focusing on those without diabetes from 2011 to 2014.Methods: We analyzed data from the 2011– 2012 and 2013– 2014 National Health and Nutrition Examination Surveys (NHANES), focusing on non-diabetic participants aged 60 and older who completed cognitive tests: Establish a Registry for Alzheimer’s disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). …”
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  14. 29454
  15. 29455

    Vaccination against the SARS-CoV-2 in individuals with comorbidities by S A Berns, M G Chashсhin, A Yu Gorshkov, O V Zhdanova, L N Ryzhakova, O A Litinskaya, O M Drapkina

    Published 2025-02-01
    “…To assess post-vaccination period and the incidence of coronavirus disease 2019 (COVID-19) in comorbid individuals vaccinated and revaccinated against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Material and methods. The study was conducted within the prospective SATURN registry, which included individuals who received various revaccination regimens against the SARS-CoV-2 (homoand heterologous regimens) based on a combination of two vaccines (GamCOVID-Vac and CoviVac). …”
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  16. 29456

    An Integrated Machine Learning Framework for Developing and Validating a Diagnostic Model of Hub Genes Related to Lipid Metabolism in Chronic Rhinosinusitis by Xiong P, Liu L, Pi J, Wang J, Lu T, Ke X, Jiang Y, Shen Y, Yang Y

    Published 2025-07-01
    “…Panhui Xiong,1,&amp;ast; Lei Liu,1,2,&amp;ast; Jingting Pi,3,&amp;ast; Ji Wang,1 Tao Lu,1 Xia Ke,1 Yu Jiang,1 Yang Shen,1 Yucheng Yang1 1Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, Mianyang Central Hospital, Mianyang, 621000, People’s Republic of China; 3Department of Otolaryngology Head and Neck Surgery, Yongchuan Hospital Affiliated of Chongqing Medical University, Chongqing, 402160, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Yucheng Yang, Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email yychxh@163.com Yang Shen, Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email sy_smile@sina.cnPurpose: The study aimed to identify key genes related to lipid metabolism in chronic sinusitis and understand their biological implications, considering the growing interest in the association between chronic sinusitis - a complex inflammatory condition - and lipid metabolism due to lipids’ role in inflammation and immunity.Methods: Gene expression data from bulk - RNA sequence was analyzed and intersected with lipid metabolism genes and WGCNA module genes from the MSigDB database. …”
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  17. 29457

    Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction by Hu H, Liu Z, Zeng J, Jiang M

    Published 2025-01-01
    “…This study aims to elucidate their effects on HFmrEF patient outcomes.Methods: We retrospectively analyzed 1,653 hFmrEF patients treated at Xiangtan Central Hospital (2015– 2020). …”
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  18. 29458

    Promotion of Random Flap Neovascularisation in Rats with Diabetes Using Botulinum Toxin Type A Through the HIF-1&amp;alpha;/VEGF Pathway by Yan HJ, Lin FM, Li JJ, Qin H, Wang YH, You CH

    Published 2025-06-01
    “…Hong-Jie Yan,1,&amp;ast; Fang-Ming Lin,2,&amp;ast; Jing-Jing Li,1 Hao Qin,1 Yi-He Wang,1 Chuan-Hua You1 1Department of Plastic and Cosmetic Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, People’s Republic of China; 2Department of Vascular Surgery, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, 570100, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Chuan-Hua You, Department of Plastic and Cosmetic Surgery, The First Affiliated Hospital of Hainan Medical University, No. 31 of Longhua Street, Longhua District, Haikou, 570102, People’s Republic of China, Tel +8615120793168, Fax +86-1083161294, Email youchuanhua3063@163.comObjective: This study aimed to investigate the effects of botulinum toxin type A (BoTA) on the neovascularisation of diabetic flaps through the factor-1alpha (HIF-1α)/vascular endothelial growth factor (VEGF) pathway.Methods: A total of 60 male Wistar rats (250– 300 g) were randomly divided into 4 groups. …”
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  19. 29459

    A Model Predicting Occult Metastases in Lateral Lymph Nodes in pN1a Stage Papillary Thyroid Cancer by Chen Y, Chen S, Mei Y, Wang F, Wei T, Wei C

    Published 2025-08-01
    “…Yan Chen,1,2,&amp;ast; Shaohua Chen,2,&amp;ast; Yujia Mei,3 Fengwei Wang,4 Teng Wei,2 Changyuan Wei1 1Department of Breast and Thyroid Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Department of Breast and Thyroid Surgery, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, People’s Republic of China; 3Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 4Health Management Centre, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Changyuan Wei, Email changyuanwei@gxmu.edu.cnObjective: This study aimed to develop and validate a nomogram for predicting occult lateral neck lymph node metastasis (LLNM) in patients with pN1a papillary thyroid carcinoma (PTC), addressing the clinical controversy surrounding prophylactic lateral neck dissection (PLND).Methods: A retrospective analysis was conducted on 128 pN1a PTC patients who underwent total thyroidectomy with bilateral central lymph node dissection and ipsilateral PLND between 2020 and 2023. …”
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  20. 29460

    Oncostatin M Drives Th2 Polarized Allergic Airway Inflammation Through Fibroblast Reprogramming and Endoplasmic Reticulum Stress by Zhang H, Chen X, Liu L, Zheng H, Yang X, Yin K, Yao Q, Li L, Yang P

    Published 2025-07-01
    “…This study investigates the role of OSM in dust mite extract (DME)-induced allergic airway inflammation and identifies a novel mechanism by which OSM drives Th2-polarized inflammation.Methods: A murine model of DME-induced airway inflammation was established. …”
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