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29381
Women’s Autonomy Decision Making Power on Postpartum Modern Contraceptive Use and Associated Factors in North West Ethiopia
Published 2019-01-01“…A P-value less than or equal to 0.05 at 95% confidence interval was set to test statistical significance. …”
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29382
Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression
Published 2025-03-01“…Specifically, we sought to elucidate the underlying mechanisms through which TBMS1 exerts its anticancer effects.Methods: The effects of TBMS1 on the viability, proliferation, and apoptosis of two liver cancer cell lines, MHCC97-H and SNU-449, were comprehensively assessed using Cell Counting Kit-8 (CCK-8), colony formation, 5-ethynyl-2′-deoxyuridine (EDU) assay, and flow cytometry assays. …”
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29383
Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidem...
Published 2024-12-01“…This study endeavors to evaluate the relationship between polymorphisms in the coding sequence (CDS) of SLCO1B1 gene and blood lipid levels before and after atorvastatin treatment among the Chinese Han adults with dyslipidemia.Patients and Methods: A total of 165 Chinese Han adults undergoing atorvastatin therapy were enrolled in this study and followed up quarterly. …”
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29384
Preoperative Prediction of a Rare and Highly Aggressive Subtype of Hepatocellular Carcinoma Based on Multimodal Imaging and Clinical Indicators
Published 2025-06-01“…Keke Chen,1,* Yuli Zhu,1,* Han Liu,2,* Minying Deng,3 Wentao Kong,4 Wenping Wang1 1Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 2Department of Ultrasound, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 3Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 4Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wentao Kong, Email breezewen@163.com Wenping Wang, Email puguang61@126.comPurpose: To develop and validate a reliable preoperative non-invasive diagnostic model for dual-phenotype hepatocellular carcinoma (DPHCC) by integrating multimodal imaging and clinical indicators, thereby facilitating clinical decision-making.Patients and Methods: 222 pathologically confirmed patients (61 with DPHCC, 161 with non-DPHCC) were retrospectively enrolled in this study and randomly assigned to training and validation cohorts in an 8:2 ratio. …”
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29385
S-values for bone marrow dosimetry in preclinical radiopharmaceutical studies with rodents
Published 2025-07-01“…Here, we aim at performing Monte Carlo simulations on digital mice phantoms including tumor xenografts, and to determine new bone marrow S-values that can potentially improve our understanding of the effect of RPTs in blood cells. Methods S-values for 177Lu were simulated in the 4D Mouse Whole Body (MOBY) phantom, a hybrid voxel-based mouse model, using GATE v9.3 MC toolkit. …”
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29386
Evaluating the Knowledge of Computed Tomography and Magnetic Resonance Imaging Parameters Between Undergraduate Students and Radiographers in Jeddah, Saudi Arabia: A Cross-Sectiona...
Published 2025-08-01“…Previous studies have showed a significant knowledge gap regarding CT and MRI parameters; thus, this study aimed to evaluate the effectiveness of university curricula and clinical practice in hospitals among undergraduate students and technologists in Jeddah.Methods: Quantitative data were collected through a validated structured cross-sectional survey administered to a cluster sample of undergraduate students and radiographers in Jeddah. …”
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29387
Predicting OSA Using Radiographs of the Airway Anatomy
Published 2024-11-01“…., Guangzhou, 510000, People’s Republic of China; 4Department of Anesthesiology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 5Department of Otolaryngology Head and Neck Surgery, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiangmin Zhang; Feng Pang, Department of Sleep Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26 Yuanchun Two Road, Guangzhou, Guangdong, 510065, People’s Republic of China, Tel +86 15013071537, Email zhangxm36@mail.sysu.edu.cn; pangf6@mail.sysu.edu.cnObjective: This study aims to analyze the tongue body shape and upper airway anatomical parameters in patients with Obstructive Sleep Apnea (OSA) and to explore the anatomical causes of OSA.Methods: A total of 345 subjects participated in this study. …”
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29388
Comparative Analysis of Clinical Efficacy and Safety of Pyrotinib Plus Capecitabine versus Trastuzumab Emtansine (T-DM1) as Second-Line Treatment for HER2-Positive Advanced Breast...
Published 2025-04-01“…This study aims to compare the clinical efficacy and safety of T-DM1 against pyrotinib plus capecitabine.Methods: Patients are females with HER2-positive, locally advanced, or metastatic breast cancer who at least 18 years old and have received anti-HER2 therapy in the past. …”
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29389
Preoperative Neutrophil-to-Albumin Ratio as a Prognostic Indicator in Advanced Gastric Cancer Undergoing Radical Gastrectomy
Published 2025-07-01“…Huaping Ye,1,* Rong Kang,2,* Mao Chen,3 Si Zhang,3 Jinfeng Yang1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 3Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinfeng Yang, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email yangjinfeng13@163.com Si Zhang, Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email 692653629@qq.comObjective: This study aimed to evaluate the prognostic significance of the preoperative neutrophil-to-albumin ratio (NAR) in patients with advanced gastric cancer undergoing radical gastrectomy.Methods: A retrospective analysis was conducted involving 526 patients diagnosed with locally advanced gastric adenocarcinoma who underwent radical gastrectomy between January 2017 and December 2019. …”
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29390
Association Between Dietary Flavonoid Intake and Cardiovascular Health in Cancer Survivors: A Cross-Sectional Study
Published 2024-10-01“…The purpose of this study was to explore the associations between dietary flavonoid intake and cardiovascular health in cancer survivors.Patients and Methods: We obtained data from the National Health and Nutrition Examination Survey (NHANES) 2007– 2008, 2009– 2010, and 2017– 2018 cycles. …”
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29391
Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses
Published 2025-06-01“…However, little is known about the causal relationship between immune factors and diseases of the reproductive system.Methods: Thorough two-sample Mendelian randomization (MR) analyses were conducted to determine the causal effects of 731 immune traits on reproductive ill-health, including abnormal spermatozoa (AS), polycystic ovary syndrome (PCOS), and spontaneous abortion (SA). …”
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29392
Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson’s Disease
Published 2025-04-01“…The present study was to test this hypothesis.Methods: EVs isolated from FGF2-primed astrocytes (FGF2-EVs) were characterized by transmission electron microscopy and nanoparticle tracking analysis. …”
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29393
A Comparison of Stereotactic Radiation Therapy in Elderly Patients with Central or Peripheral Stage I-II (T1-3 N0 M0) Non-Small Cell Lung Cancer
Published 2024-11-01“…Xiaoqin Ji,1,* Xuebing Shi,2,* Jun Hu,3 Wanrong Jiang,3 Bin Zhou,3 Houlong Zhou,3 Xi Yuan,3 Yikun Li,3 Hua Huang,3 Jiasheng Wang,3 Wei Ding,3 Yong Wang,4 Xiangdong Sun3 1Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 2Department of Radiation Oncology, Nanjing Jiangbei Hospital, Nanjing, People’s Republic of China; 3Department of Radiation Oncology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 4Department of Outpatient Clinic, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yong Wang; Xiangdong Sun, Email 292917354@qq.com; sunxd_81@126.comPurpose: The objective of this study was to compare the clinical outcomes of stereotactic body radiation therapy (SBRT) in elderly patients aged 65 or older with clinical stage I–II non-small-cell lung cancer (NSCLC), specifically examining the differences between centrally located lung tumors and peripherally located lung tumors.Methods: From April 2009 to January 2020, a total of 136 patients with 136 tumors (65 central, 71 peripheral; NSCLC) at an early stage (T1-3N0M0) were treated with SBRT at a single institution. …”
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29394
Clinical Features of Juvenile Open-angle Glaucoma
Published 2025-06-01“…Juvenile open-angle glaucoma (JOAG) is a genetically determined disease of young age, which is diagnosed before the 40, which is based on anomalies in the structure of the drainage system of the eye.Objective: to identify the features of morphometric and biomechanical parameters of the fibrous capsule in patients with JOAG.Materials and methods. 19 eyes of 10 patients with JOAG were examined. …”
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29395
Impact of Fungal Co-Infection on Teicoplanin Plasma Trough Concentration in Critically Ill Adults: A Novel Consideration for Dose Adjustment
Published 2025-06-01“…However, the effect of fungal co-infection on the plasma trough concentration (Cmin) of teicoplanin in critically ill patients remains unclear.Materials and Methods: A retrospective cohort study was carried out. …”
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29396
Relative contribution of diet and physical activity to increased adiposity among rural to urban migrants in India: A cross-sectional study.
Published 2020-08-01“…In this study, we investigated the relative contribution of energy intake and expenditure and specific diet and activity behaviours to greater adiposity among urban migrants in India.<h4>Methods and findings</h4>The Indian Migration Study was conducted between 2005 and 2007. …”
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29397
The Aggregate Index of Systemic Inflammation (AISI) is a Novel IgA Nephropathy Prognosis Predictor
Published 2025-04-01“…We aimed to evaluate its predictive value in IgAN.Patients and Methods: This retrospective single-center study included 1792 biopsy-confirmed IgAN patients from October 2019 to September 2023 with> 12-month follow-up. …”
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29398
Changes in Serum Bilirubin and Total Bile Acids During Biologic Therapy in Patients with Ulcerative Colitis: A Retrospective Study
Published 2025-07-01“…This study aims to assess their monitoring potential in UC during biologic therapy.Methods: We conducted a retrospective single-center study including 138 UC patients and 150 controls with normal colonoscopy results. …”
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29399
Cancer-Derived Exosomal LINC01615 Induces M2 Polarization of Tumor-Associated Macrophages via RBMX-EZH2 Axis to Promote Colorectal Cancer Progression
Published 2025-06-01“…However, the specific role of cancer derived exosomal lncRNA in the M2 polarization of macrophages remains largely unknown.Methods: Bioinformatic analysis was used to screen out the differentially expressed lncRNAs in colorectal cancer (CRC). …”
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29400
Auxiliary Diagnosis of Pulmonary Nodules&rsquo; Benignancy and Malignancy Based on Machine Learning: A Retrospective Study
Published 2025-06-01“…Its nonspecific clinical presentation and heterogeneous imaging characteristics hinder accurate differentiation between benign and malignant lesions, while biopsy’s invasiveness and procedural constraints underscore the critical need for non-invasive early diagnostic approaches.Methods: In this retrospective study, we analyzed outpatient and inpatient records from the First Medical Center of Chinese PLA General Hospital between 2011 and 2021, focusing on pulmonary nodules measuring 5– 30mm on CT scans without overt signs of malignancy. …”
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