Effectiveness and safety of lysozyme chloride-based cream on healing of grade-two pressure ulcers: A pilot study by Glogovac-Kosanović Milkica, Bućma Tatjana, Prtina Draško, Gajić Aleksandar, Šukalo Aziz, Mehić Meliha, Tanović-Avdić Amna, Glamočlija Una

“…This study aimed to evaluate the efficacy and safety estimates of lysozyme-based cream in the treatment of pressure ulcers of grade two according to Yarkony-Kirk scale. Methods: Adult patients with neurological diseases and severe functional deficits with grade-two pressure ulcers according to Yarkony-Kirk scale were included. …”
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Shared and distinct brain activation patterns of acupoints HT7, ST36, and KI4: a task-based fMRI study by Liyu Hu, Liyu Hu, Jinhuan Zhang, Xiaoxiong Wu, Xingxian Huang, Xinbei Li, Xingchen Liu, Hanqing Lyu, Nan Yang, Jinping Xu, Haibo Yu

“…ObjectiveWe aimed to investigate the shared and distinct of brain responses to manual acupuncture at HT7, ST36, and KI4.MethodsSixteen healthy participants receiving acupuncture at HT7, 19 at ST36, and 16 at KI4. …”
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Optimized Flare Performance Analysis Through Multi-Modal Machine Learning and Temporal Standard Deviation Enhancements by Said Boumaraf, Pengfei Li, Muaz Al Radi, Fares Oussama Abdelhafez, Abderaouf Behouch, Khalid Yousef Al Awadhi, Hamad Karki, Sajid Javed, Jorge Dias, Naoufel Werghi

“…The results demonstrate significant improvements in estimation accuracy and reliability compared to traditional methods, achieving an R-squared score of 94.77% with minimal FM data. …”
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Prediction of new HIV infection in men who have sex with men based on machine learning: secondary analysis of a prospective cohort study from Western China by Kangjie Li, Guiqian Shi, Cong Zhang, Bing Lin, Yi Tao, Qian Wang, Haijiao Zeng, Jielian Deng, Lei Zou, Biao Xie, Xiaoni Zhong

“…Objective This study aimed to construct a model based on machine learning to predict new HIV infections in HIV-negative men who have sex with men (MSM).Methods This is a secondary analysis of a previous random clinical trial aiming to evaluate the preventive effects of PrEP on new HIV infection in MSM. …”
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Effects of mental fatigue on biomechanical characteristics and risk associated with non-contact anterior cruciate ligament injuries during landing by Bosong Zheng, Bosong Zheng, Zeyang Zhang, Zeyang Zhang, Zeyi Zhang, Zeyi Zhang, Youping Sun, Youping Sun, Yao Xiao, Mengjie Li, Mengjie Li

“…ObjectiveTo investigate and compare the effects of mental fatigue (MF) on biomechanical characteristics associated with non-contact anterior cruciate ligament injury (NC-ACLI) in male college students during stop-jump (SJ) and single-leg landing (SL), and whether it increases NC-ACLI risk.MethodsMF was induced by a 45-min Stroop task and measured using the visual analogue scale for MF (VAS-MF), while motion capture, force platforms, and surface electromyography (SEMG) evaluated biomechanical variables before and after MF induction in thirty-six subjects. …”
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Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas by Sunil Dhungel, Sunil Dhungel, Shavana R. L. Rana, Arun Kumar Neopane, Barun Mahat, Bipin Kumar Shrestha, Yesha Shree Rajaure, Bikalp Thapa, Naveen Phuyal, Naresh Manandhar, Udaya Shrestha, Suraj Parajuli, Taraman Amatya

“…This study examines the impact of high-altitude exposure on frontal, parietal, temporal, and occipital lobes in climbers in the Nepali Himalayas, aiming to enhance understanding of altitude-related cognitive decline.MethodsA cross-sectional cohort study was conducted with 76 participants, including 46 non-selected individuals (NOSCL) and 30 selected climbers divided into Everest (EMCL, n = 12), Kanchanjanga (KMCL, n = 9), and Manaslu (MMCL, n = 9) groups. …”
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Segmentectomy-oriented anatomical model for enhanced precision surgery of the left upper lobeCentral MessagePerspective by Shunichiro Matsuoka, MD, Takashi Eguchi, MD, PhD, Maho Seshimoto, MD, Shuji Mishima, MD, Daisuke Hara, MD, Hirotaka Kumeda, MD, Kentaro Miura, MD, PhD, Kazutoshi Hamanaka, MD, PhD, Kimihiro Shimizu, MD, PhD

“…Objective: To optimize surgical outcomes and minimize complications in complex segmentectomy of the left upper lobe, we investigated the topographical anatomy of the left upper lobe and developed a segmentectomy-oriented anatomical model. Methods: A state-of-the-art 3-dimensional computed tomography workstation was used to visualize the intersegmental planes and associated veins to categorize the anatomical patterns influencing surgical procedures during left upper lobe segmentectomy. …”
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Experiences among patients with short bowel syndrome and their caregivers: Insights from targeted forums by Carine Khalil, Christopher V. Almario, Taylor Dupuy, Sam Eberlein, Shirley Paski, Bram P. Raphael, Brennan M.R. Spiegel

“…In this study, we conducted social netnography of online posts to examine the perspectives, experiences, and concerns among patients with SBS and their caregivers. Methods: We extracted 20,221 publicly available posts from SBS-specific sites and other e-forums between 1/1/2010-1/11/2021. …”
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Resilience, personal recovery, and quality of life for psychiatric in-patients prior to hospital discharge: demographic and clinical determinants by Ernest Owusu, Wanying Mao, Reham Shalaby, Hossam Eldin Elgendy, Belinda Agyapong, Ejemai Eboreime, Mobolaji A. Lawal, Nnamdi Nkire, Carla T. Hilario, Yifeng Wei, Peter Silverstone, Pierre Chue, Xin-Min Li, Wesley Vuong, Arto Ohinmaa, Valerie Taylor, Andrew J. Greenshaw, Vincent I. O. Agyapong, Vincent I. O. Agyapong

“…This paper examines how demographic and clinical factors predict resilience, personal recovery, and quality of life.MethodsData were collected from psychiatric inpatients before discharge using REDCap, an online survey platform. …”
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Evaluation of a dynamic navigation system for endodontic microsurgery: study protocol for a randomised controlled trial by Bing Han, Xiaoyan Wang, Li Peng, Yuhan Wang, Chunyan Zheng, Zuhua Wang, Yuchun Sun

“…This study is devoted to comparing the clinical outcomes of the DNS technique with those of the freehand technique.Methods and analysis Sixteen patients will be randomly assigned to one of two groups. …”
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Epidemiology and future trend predictions of ischemic stroke based on the global burden of disease study 1990–2021 by Jiayu Liu, Aoxi Xu, Zhifeng Zhao, Bin Ren, Zhao Gao, Dandong Fang, Bo Hei, Junzhao Sun, Xiangyang Bao, Lin Ma, Xiaoque Zheng, Yuxin Wang, Hecheng Ren, Guan Wang, Li Zhu, Jianning Zhang

“…Methods We stratify epidemiological parameters by sex, age, the World Bank’s classification of economies, and sociodemographic index (SDI) levels. …”
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Echocardiographic video-driven multi-task learning model for coronary artery disease diagnosis and severity grading by Ying Guo, Yu-Han Cai, Tao Xu, Xin-Yang Song, Hong-Xia Guo, Min Dong, Dong Ni, Hui Li, Fang Wang, Wu-Feng Xue

“…IntroductionEchocardiography is a first-line noninvasive test for diagnosing coronary artery disease (CAD), but it depends on time-consuming visual assessments by experts.MethodsThis study constructed an echocardiographic video-driven multi-task learning model, denoted Intelligent echo for CAD (IE-CAD), to facilitate CAD screening and stenosis grading. …”
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Feasibility of calcium hydroxyapatite (Radiesse®) for improving the biomechanical properties of facial burn scars: A pilot study by Mariana del Carmen Radilla-Flores, Erik Agustín Márquez-Gutiérrez, Mario Vélez-Palafox, María Isabel Castrejón-Vázquez, Osiris Cristina Chávez-Flores, Mario Chopin-Doroteo, Maykel González-Torres

“…Objective: To evaluate the potential effects of CaHA injections on the biomechanical properties of facial burn scars and to compare these effects with those of untreated skin. Methods: A prospective longitudinal feasibility study was conducted with 13 patients who had mature facial scars (2–5 years) covering more than 90% of the face, including hypertrophic, atrophic, and/or keloid scars. …”
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OUR EXPERIENCE OF HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY FOR PATIENTS WITH ADVANCED GASTRIC CANCER by A. D. Kaprin, V. M. Khomyakov, D. D. Sobolev, L. V. Bolotina, A. B. Ryabov, V. E. Khoronenko, M. M. Soboleva, L. V. Kramskaya

“…Improvement of the results of treatment of patients with locally advanced and metastatic gastric cancer. Material and methods. From the 2010–2014 we performed 30 surgeries using techniques HICT. …”
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Role of laparoscopic surgery in blunt abdominal trauma; retrospective analysis in a tertiary trauma center by Rifan Alyami, Ahad E. Alotaibi, Leen Almohayya, Ajyad Al Jawad, Raghad Almukhayzim, Abeer Alhoumedan, Rakan S. Aldusari

“…This study aims to reduce unnecessary laparotomies and assess the effectiveness of laparoscopy in managing patients with blunt abdominal trauma. Methods The study is a descriptive retrospective study using the medical records of patients with blunt abdominal trauma who were managed with laparoscopy in the Department of General Surgery, King Abdulaziz Medical City in Riyadh. …”
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Identifying risk factors for loss to follow-up in adults living with HIV in a high-burden district in Ghana by Benedicta Ayiedu Mensah, Henrietta E. Mensah-Brown, Frederica D. Partey, Christabel Addo, Gertrude Buah, Gifty A. Afudego, Daniel Okyere, Mary Tetteh, Ernest Boateng, Michael Wilson, Elijah Paintsil

“…Thus, this study aimed to explore the risk factors influencing LTFU among PLWHIV in a high-burden district in Ghana. Methods A retrospective analysis was conducted using medical records of 401 patients who initiated Antiretroviral Therapy (ART) between January 1st, 2011, and December 31st, 2021, in a high-burden district in Ghana and data extraction period of January to December 2022. …”
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Distinct features of three clinical subtypes in 533 patients with primary hypertrophic osteoarthropathy by Xilei Cai, Xiujuan Yang, Pengyue Zhang, Ziyue Dou, Zilian Chen, Chongzhi Zhu, Weiwei Xu, Xinchen Wang, Xiaodan Hong, Zhenhua Zhang

“…This study aimed to determine the distribution of the three clinical subtypes of PHO and compare their clinical characteristics using a large global sample. Methods A systematic literature search was conducted in multiple databases to categorize cases into complete form (CO), incomplete form (IN), and fruste form (FR). …”
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Prescription dose and optimisation strategies in MR-guided online adaptive radiotherapy for kidney tumours: a two-step planning analysis by Takaya Yamamoto, Noriyoshi Takahashi, Shohei Tanaka, Rei Umezawa, Yu Suzuki, Keita Kishida, So Omata, Kazuya Takeda, Hinako Harada, Kiyokazu Sato, Noriyuki Kadoya, Keiichi Jingu

“…However, the ideal strategy for prescription dose selection and reoptimisation remains unclear. Methods This single-centre planning study evaluated kidney tumours located within 1 cm of gastrointestinal OARs. …”
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Vaccine-induced T cell responses correlate with reduced risk of severe COVID-19 in a placebo-controlled efficacy trialResearch in context by Nina Hertoghs, Sanne Roels, Matthias Brückner, Jerald Sadoff, Barbara L. Banbury, Nicholas K. Akers, Bryan Howie, Harlan S. Robins, Griet A. van Roey, Jeroen T.B.M. Tolboom, Veronica V. Rezelj, Jenny Hendriks, Hanneke Schuitemaker, Daniel J. Stieh, Mathieu Le Gars

“…The purpose of this study is to investigate whether signatures of the T-cell response contribute to protection against (severe) COVID-19. Methods: T cell receptor (TCR) sequencing was conducted using pre-vaccination and 29 days post-vaccination PAXgene samples from 396 participants in the phase 3 efficacy trial, ENSEMBLE. …”
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Tacrolimus concentration/dose ratio as a therapeutic drug monitoring strategy: The influence of gender and comedication by Rančić Nemanja, Dragojević-Simić Viktorija, Vavić Neven, Kovačević Aleksandra, Šegrt Zoran, Drašković-Pavlović Biljana, Mikov Momir

“…Methods. This prospective case series study included 54 patients, in which the unit of monitoring was outpatient examination (1,872) of the renal transplant patients. …”
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