Adalimumab in Focus: Evaluating Effectiveness and Safety in Non-Infectious Uveitis at a Tertiary Referral Center in Türkiye by Berru Yargı Özkoçak, Çiğdem Altan, Burcu Kemer Atik, Berna Başarır

“…Objectives: To evaluate the indications, efficacy, and safety of adalimumab (ADA) in treating active non-infectious uveitis (NIU) in the Turkish population in a real-world setting. Materials and Methods: This retrospective observational study included patients diagnosed with NIU treated with ADA on-label. …”
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Predictive Value of Optical Coherence Tomography Biomarkers in Patients with Persistent Diabetic Macular Edema Undergoing Cataract Surgery Combined with a Dexamethasone Intravitrea... by Giuseppe Fasolino, Maryam Lazaar, Domenico Giovanni Della Rocca, Silke Oellerich, Sorcha Ní Dhubhghaill

“…Limited data exist on the role of optical coherence tomography (OCT) biomarkers as predictors of success in non-responders to anti-VEGF treatment undergoing simultaneous cataract surgery and dexamethasone intravitreal implant (DEX-I). <b>Methods:</b> This study was designed as a retrospective analysis of patients with DME who were refractory to anti-VEGF treatment but underwent cataract surgery and received a DEX-I at the time of surgery. …”
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Association of alcohol abstinence with risk of hyperuricemia in rural Chinese adults: the Henan Rural Cohort Study by Xiaokang Dong, Lulu Zhang, Ning Kang, Huanxiang Zhang, Wei Liao, Xiaotian Liu, Pengling Liu, Lei Yin, Chongjian Wang

“…This study aimed to evaluate the associations of abstinence with HUA in rural Chinese adults. Methods This was a cross-sectional study of 38,855 participants (15,371 males and 23,484 females) using the baseline data (2015–2017) from the Henan Rural Cohort Study. …”
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Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress by Surjit Bhattacharjee, Abhirup Paul, Aradhana Jana, G. Meher Unnati, Deepak R., Ye Miao, Honglin Lu, Guoxin Shen, Neelam Mishra

“…Protein phosphatase 2A (PP2A) are a class of Ser/Thr protein phosphatases which are present widely across plant species and facilitate plant responses to biotic and abiotic stresses, and hormone treatment. Methods Using BLASTp, tea PP2A genes were found and their physicochemical characteristics (ExPASy), subcellular localization, and intron-exon structure (GSDS) were described. …”
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Predictors and Correlates of Depression and Anxiety Symptom Trajectories in a Large Digital Mental Health Provider: Retrospective Analysis of Data From Rula Health by Kelsey Lynn McAlister, Lara Baez, Douglas Newton, Sam Seiniger, Amy Pearlman, Allie Woodhouse, Jennifer Huberty

“…We aimed to (1) explore the trajectories of anxiety and depression symptoms and (2) examine the impact of demographics and primary diagnosis on depression and anxiety trajectories. MethodsWe retrospectively analyzed longitudinal symptom data from adults receiving therapy through Rula Health, an MBC-based DMHI. …”
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Early Effects of Perfluorohexyloctane Ophthalmic Solution on Patient-Reported Outcomes in Dry Eye Disease: A Prospective, Open-Label, Multicenter Study by Jason Bacharach, Shane R. Kannarr, Anthony Verachtert, Preeya K. Gupta, Moataz Razeen, Megan E. Cavet, Jason L. Vittitow, Jacob Lang, Thomas M. Chester, Jillian F. Ziemanski, Darrell E. White

“…This study evaluated patient-reported outcomes early in treatment with PFHO. Methods This prospective, multicenter, open-label, phase 4 study enrolled adults with a history of DED for ≥ 6 months. …”
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Analysis of Quality Indicators of Preanalytical and Analytical Phases in Cervical Pap Smear Cytology: A Cross-sectional Study by Gracy Jeba Rani, S Sowmya, ES Keerthika Sri

“…Aim: To assess the quality indicators of the preanalytical and analytical phases of cervical Pap smear cytology in order to evaluate Non Conformity (NC) through root cause analysis for appropriate corrective and preventive measures. Materials and Methods: The cross-sectional study was conducted in the cytology section of the Department of Pathology at Mahatma Gandhi Medical College and Research Institute in Puducherry, India, planned and executed over a period of twelve months, starting in June 2023 and concluding in May 2024. …”
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Shared pyroptosis pathways and crosstalk genes underpin inflammatory links between periodontitis and atherosclerosis by Pinxin Zhan, Zhiying Feng, Xinqi Huang, Haoyang Xu, Shijun Xu, Shan Wang

“…The goal was to uncover common regulatory mechanisms underlying these two inflammatory conditions. Methods: Gene expression datasets for PD (GSE10334) and AS (GSE43292) were retrieved from public databases. …”
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Pattern and Prevalence of Retinal Vein Occlusion in Bhutan: A 3-Year National Survey at Vitreoretinal Clinics by Rai BB, Dorji P, Maddess T

“…Bhim B Rai,1,2 Phuntsho Dorji,2 Ted Maddess1 1John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; 2Department of Ophthalmology, JDW National Referral Hospital, Thimphu, BhutanCorrespondence: Bhim B Rai, Building 131, Garran Road, John Curtin School of Medical Research, Australian National University, Canberra, ACT, 2601, Tel +61 2 61259253, Email bhim.rai@anu.edu.auPurpose: We conducted this study to determine the pattern and prevalence of retinal vein occlusion (RVO) in Bhutan to inform national health policy as no data has been compiled previously.Methods: A retrospective cross-sectional survey was conducted over 3 years, including all new RVO cases. …”
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Short Term Outcomes Utilizing Custom Total Talus Replacement with Subtalar Arthrodesis for Revision and Complex Total Ankle Arthroplasty by Kevin Horner MD, Kyle M. Schweser MD

“…Our hypothesis is that custom 3D printed talar body replacements lead to good outcome scores and patient satisfaction scores. Methods: We performed a retrospective chart review on 8 patients (9 TTRs) who underwent a TTR at our institution between May 2019 and October 2023. …”
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Natural history of the aortic wall changes in adults with the degenerative tricuspid aortic valve stenosis: The morphometric proofs and implications for echocardiography by Borović Saša D., Labudović-Borović Milica M., Todorović Vera N., Rakočević Jelena T., Marinković-Erić Jelena M., Kostić Jelena V., Trifunović Zoran, Milojević Predrag S.

“…The aim of this study was to grade the histopathological changes in the wall of the nonseverely dilated ascending aorta in patients with the severe, calcific TAV stenosis and to correlate them with the echocardiographic parameters in order to analyze when the ascending aorta should be replaced simultaneously with the aortic valve replacement (AVR). Methods. The samples from 37 patients subjected to the AVR and the samples from the control group were analyzed morphologically. …”
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Risk Factors for Correction Loss of Vertebral Slippage after Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgery for Lumbar Degenerative Spondylolisthesis by Yoshiaki Hiranaka, Shingo Miyazaki, Kohei Kuroshima, Masao Ryu, Shinichi Inoue, Takashi Yurube, Kenichiro Kakutani, Ko Tadokoro

“…We aimed to identify the risk factors for correction loss after minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and to determine the effect of postoperative correction loss on postoperative clinical outcomes. Methods: In this retrospective study, a total of 111 patients (mean age 69.5 years, 37 men and 74 women) who underwent single-level MIS-TLIF with slippage reduction for lumbar degenerative spondylolisthesis and were followed up for >1 year were included in the study. …”
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Factors influencing outcome satisfaction after cataract surgery: patient-reported insights from the RayPro database by Josefina Botta, Allon Barsam, Andrzej Dmitriew, Roger Zaldivar, William F. Wiley, Stanley Windsor

“…The purpose of this study is to investigate determinants of patient satisfaction following cataract surgery by analysing PROMs. Methods A multicentre, retrospective, observational study was conducted analysing the PROMs recorded in the RayPro database (Rayner, Worthing, UK) from May 2019 to February 2024. …”
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Anatomic and Functional Outcomes of Lamellar Macular Hole and Epiretinal Membrane Foveoschisis Surgery: Predictive Factors and Associated Complications &mdash; A Retrospective Inte... by Er-reguyeg Y, Doukkali S, Hébert M, You EL, Bourgault S, Caissie M, Tourville É, Dirani A

“…Yosra Er-reguyeg,1 Sihame Doukkali,2 Mélanie Hébert,2 Eunice Linh You,2 Serge Bourgault,2 Mathieu Caissie,2 Éric Tourville,2 Ali Dirani2 1Faculty of Medicine, Laval University, Quebec City, Quebec, Canada; 2Department of Ophthalmology, Hospital Saint-Sacrement, Laval University, Quebec City, Quebec, CanadaCorrespondence: Ali Dirani, Hôpital du Saint-Sacrement, 1050 Chemin Sainte-Foy, Québec, QC, D2-44C, Canada, Tel +1 418 525 4444, Email drdirani@gmail.comPurpose: To analyze the anatomic and functional outcomes of lamellar macular hole (LMH) and epiretinal membrane foveoschisis (ERMF) surgery.Patients and Methods: This is a retrospective interventional cohort study of ninety patients with unilateral idiopathic LMH or ERMF who underwent pars plana vitrectomy (PPV) with membrane peeling between 2014 and 2021. …”
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Social behavioral analysis of the influence of residential area and grade on pupils’ myopia rate: a cross-sectional survey in Nanjing, China by Yi-jing Xie, Yi-jing Xie, Wen Bai, Wen Bai, Yun-fan Zhou, Yun-fan Zhou, Xin Shui, Xin Shui, An-yi Ren, An-yi Ren, Ying Tang, Ying Tang, Xuan Zhou, Xuan Zhou, Qin Jiang, Qin Jiang, Wei-hong Shang, Wei-hong Shang

“…ObjectiveThis study aims to examine the prevalence of myopia among pupils in different residential areas (city center, nearby suburbs, and far suburbs) and grade levels (lower, middle, and upper), analyzing social behaviors and risk factors to guide early intervention.MethodsA cross-sectional survey was conducted with elementary students across various regions in Nanjing. …”
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Real-world clinical insights and aqueous humor biomarker analysis of diabetic macular edema subtypes classified by OCT following intravitreal injections by Liangzhang Tan, Shoukuan Liu, Wenrui Linghu, Yifeng Ke, Yongtao Li, Emmanuel Eric Pazo, Xinjun Ren

“…Methods Ninety-four eyes from seventy-eight patients were enrolled between July 1, 2018, and June 30, 2023. …”
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[Translated article] The influence of socioeconomic status and psychological factors on surgical outcomes of the carpometacarpal osteoarthritis of the thumb by A.M. Martín-Fuentes, C. Ojeda-Thies, M. Campoy-Serón, C. Ortega-Romero, L.R. Ramos-Pascua, D. Cecilia López

“…Objective: This study aimed to investigate to what extent people with carpometacarpal thumb osteoarthritis that are socioeconomically disadvantaged and have psychological disorders report higher pain levels and worse patient-rated upper-extremity functionality after surgical treatment. Material and method: A single centre, retrospective observational cohort study analysing 100 patients diagnosed with thumb carpometacarpal osteoarthritis between 2013 and 2019. …”
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Large language model comparisons between English and Chinese query performance for cardiovascular prevention by Hongwei Ji, Xiaofei Wang, Ching-Hui Sia, Jonathan Yap, Soo Teik Lim, Andie Hartanto Djohan, Yaowei Chang, Ning Zhang, Mengqi Guo, Fuhai Li, Zhi Wei Lim, Ya Xing Wang, Bin Sheng, Tien Yin Wong, Susan Cheng, Khung Keong Yeo, Yih-Chung Tham

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P300 event-related potentials as diagnostic biomarkers for attention deficit hyperactivity disorder in children by Chuanxue Tan, Chuanxue Tan, Huimin Zhou, Anqi Zheng, Miao Yang, Chunyang Li, Ting Yang, Tingyu Li, Jie Zhang

“…ObjectivesThis study aimed to evaluate the utility of P300 event-related potentials (ERPs) as neurophysiological biomarkers for diagnosing attention deficit hyperactivity disorder (ADHD) and to establish preliminary diagnostic thresholds for their use.MethodsA total of 106 children diagnosed with ADHD and 66 healthy controls were enrolled. …”
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Immediate efficacy of acupuncture combined with active exercise as 10 min rapid therapy for pain and movement disorders in patients suffering from acute stiff neck: protocol for a... by Fan-rong Liang, Ya Huang, Qifu Li, Xin Tang, Taipin Guo, Gaoyangzi Huang, Xianmei Pei, Ziwen Chen, Zili Liu, Jinbo Sun, Jianglong Liao

“…Secondary outcomes include the effective rate at other time points (0–1, 2, 4, 6 and 8 min), Visual Analogue Scale score and cervical range of motion. …”
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