Evaluation of a minimally invasive cell sampling device coupled with assessment of trefoil factor 3 expression for diagnosing Barrett's esophagus: a multi-center case-control study... by Caryn S Ross-Innes, Irene Debiram-Beecham, Maria O'Donovan, Elaine Walker, Sibu Varghese, Pierre Lao-Sirieix, Laurence Lovat, Michael Griffin, Krish Ragunath, Rehan Haidry, Sarmed S Sami, Philip Kaye, Marco Novelli, Babett Disep, Richard Ostler, Benoit Aigret, Bernard V North, Pradeep Bhandari, Adam Haycock, Danielle Morris, Stephen Attwood, Anjan Dhar, Colin Rees, Matthew D D Rutter, Peter D Sasieni, Rebecca C Fitzgerald, BEST2 Study Group

“…The objective of this study was to determine whether a novel approach using a minimally invasive cell sampling device, the Cytosponge, coupled with immunohistochemical staining for the biomarker Trefoil Factor 3 (TFF3), could be used to identify patients who warrant endoscopy to diagnose BE.<h4>Methods and findings</h4>A case-control study was performed across 11 UK hospitals between July 2011 and December 2013. …”
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Outcomes Following Conversion of Ankle Fusion to Transfibular Total Ankle Arthroplasty in Complex Patients by Thomas Wood, Mark Arthur MD, Lew C. Schon MD, Morgan Motsay BS, Zijun Zhang PhD, MD

“…Patient reported outcome measures (PROMs) were analyzed with Short Form-12 (SF-12), Visual Analog Scale (VAS), and the Ankle Osteoarthritis Scale (AOS). …”
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Morbidity from primary glaucoma and its gender-specific aspects amongst the population of Siberian industrial town by A. L. Onischenko, A. V. Kolbasko, N. M. Zhilina, A. V. Zacharova, A. E. Vlasenko

“…Aim: To analyze visual morbidity attributable to primary glaucoma, its eight-year dynamics, and gender differences in Siberian industrial town inhabitants.Methods: Medical records (out-patient and in-patient departments) from the database of the sectional information analysis center of Novokuznetsk Health Administration over an eight-year period (2004-2011) were studied. …”
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Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study by Zhongxuan He, Monika Salvage, Corinna A Noel

“…ObjectiveOur study aimed to evaluate the Cayuga County Overdose Data Dashboard’s acceptability, use, and perceived effectiveness in disseminating overdose data and resources. MethodsFollowing the launch of the dashboard, an online Qualtrics survey collected feedback from individuals older than 18 years of age living or working in Cayuga County, asking respondents to reflect upon their experience using the dashboard. …”
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Platform Technology for Extended Reality Biofeedback Training Under Operant Conditioning for Functional Limb Weakness: Protocol for the Coproduction of an at-Home Solution (React2H... by Anirban Dutta, Abhijit Das

“…MethodsWe propose to use an experience-based co-design framework to engage patients with FND, caregivers, and health care professionals in collaboratively designing the XR platform. …”
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The C-reactive protein-to-albumin ratio as a diagnostic biomarker for rheumatoid arthritis: a cross-sectional NHANES analysis by Fan Yang, Weihua Sang, Yongqing Liu, Jun Wang

“…This cross-sectional study investigates the potential relationship between CAR and RA in United States adults, develops a clinical prediction model, and validates its effectiveness.ObjectiveTo investigate the association between the CAR and RA using data from the National Health and Nutrition Examination Survey (NHANES).MethodsThis large-scale, cross-sectional study analyzed data from the NHANES database between 1999 and 2018 (excluding 2011–2014). …”
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Clinical, functional and aberrometric parallels in the treatment of the neovascular form of age-related macular degeneration by M. M. Magomedova, A.-H. D. Aliyev, S. I. Zakieva, Z. N. Maksudova, M. T. Mikailova

“…Purpose: to analyze clinico-functional and aberrometric parameters of patients with the neovascular form of age–related macular degeneration (nAMD) treated by the anti-VEGF drug brolucizumab. Material and methods. The study involved 59 patients (59 eyes) aged 55 to 75 years, divided into two groups depending on the type of treatment. …”
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The Impact of Cataract Surgery on Vision-Related Quality of Life and Psychological Distress in Monocular Patients by Xuepei Li, Jianqiang Lin, Zidong Chen, Guangming Jin, Danying Zheng

“…To determine the changes in vision-related quality of life and psychological distress after cataract surgery in monocular patients and to compared these with a control group of age- and gender-matched binocular patients. Methods. We enrolled 40 monocular patients and 40 binocular patients who underwent cataract surgery from August 2017 to December 2018. …”
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Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled... by Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

“…Specifically, we aim to investigate whether the VR game “Sweet Dive VR” (SDVR), designed for children aged between 6 and 12 years to play with 1 caregiver, can alleviate anxiety and pain during different types of needle punctures and Kirschner-wire removal. MethodsA prospective multicenter randomized clinical trial will be conducted. …”
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A deep learning model for radiological measurement of adolescent idiopathic scoliosis using biplanar radiographs by Kunjie Xie, Suping Zhu, Jincong Lin, Yi Li, Jinghui Huang, Wei Lei, Yabo Yan

“…We developed a deep-learning model that could automatically measure spinal alignment parameters in biplanar radiographs. Methods In this study, our model adopted ResNet34 as the backbone network, mainly consisting of keypoint detection and CA measurement. …”
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Clinical Features, Prognosis, and Long-Term Response to Ranibizumab of Macular CNVs in Pattern Dystrophies Spectrum: A Pilot Study by Lorenzo Casillo, Stefano Tricarico, Laura Contento, Enzo M. Vingolo

“…The mean goal is to identify possible disease biomarkers and to evaluate the long-term prognosis of CNVs in PD. Materials and Methods. A retrospective study of 42 patients with naïve CNV (26 PD and 16 AMD), for a total of 47 eyes (29 eyes in the PD group and 18 eyes in the AMD group). …”
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Compatibility of the CEN-ISO/TS 82304-2 Health App Assessment Framework With Catalan and Italian Health Authorities’ Needs: Qualitative Interview Study by Petra Hoogendoorn, Mariam Shokralla, Romy Willemsen, Nick Guldemond, María Villalobos-Quesada

“…ObjectiveThis study aims to examine the compatibility of the TS with the needs of Catalan and Italian health authorities. MethodsSemistructured interviews were conducted with key informants from a regional (Catalonia in Spain) and national (Italy) health authority, and a thematic analysis was carried out. …”
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Association between the triglyceride glucose index and long-term outcomes in patients with acute coronary syndrome and chronic kidney disease by Feng Wang, Wendi Huang, Chonghao Shi, Yongfu Zhu, Weicheng Ni

“…This study endeavors to bridge this gap by investigating the relationship between the TyG index and outcomes among this unique patient cohort. Methods Patients having ACS with CKD were recruited from January 2013 to December 2021. …”
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Dietary and Supplement Intake of Lutein and Zeaxanthin: How Much Do We Get and How Much Do We Need? by Susan Hazels Mitmesser, Qian Ye, Prasad P. Devarshi, Ryan W. Grant

“…Objective: To determine the nutrient intake status of L+Z in US children (6–18 years) and adults (19–64 years), and how dietary supplements contribute to the total intake level of L+Z. Methods: Data from NHANES 2003-08 cycles were used to estimate the mean intakes of L+Z from food and food + supplements (F+S). …”
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Residential exposure to municipal solid waste incinerators and health effects: a systematic review with meta-analysis by Isabella Bottini, Simona Vecchi, Manuela De Sario, Lisa Bauleo, Alessandro Trentalange, Paola Michelozzi, Carla Ancona

“…The aim of this study is to update and synthesize evidence on the health effects of residential exposure to MSWIs. Methods A systematic review with meta-analysis was conducted following PRISMA guidelines. …”
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The Construction and Application of a Clinical Decision Support System for Cardiovascular Diseases: Multimodal Data-Driven Development and Validation Study by Shumei Miao, Pei Ji, Yongqian Zhu, Haoyu Meng, Mang Jing, Rongrong Sheng, Xiaoliang Zhang, Hailong Ding, Jianjun Guo, Wen Gao, Guanyu Yang, Yun Liu

“…This study offers new ideas for the prevention and management of CVDs. MethodsThis study designed a clinical decision support system (CDSS) with data, learning, knowledge, and application layers. …”
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Assessing the Impact of a Virtual Reality Cognitive Intervention on Tennis Performance in Junior Tennis Players: Pilot Study by Joaquin A Anguera, Aleem Choudhry, Michael Seaman, Dominick Fedele

“…This custom cognitive training program targeted specific cognitive control abilities including attention, working memory, and goal management. MethodsData were collected from a cohort of tennis players in a randomized controlled trial design led by the dedicated research team. …”
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Health‐Related Quality of Life One Year After Intensive Care Unit Admission for COVID‐19: A Retrospective, Cross‐Sectional, Longitudinal Observational Study by Carina M. Samuelsson, Netha Hussain, Avril Drummond, Carina U. Persson

“…Therefore, the aims were to describe HRQoL and to identify early factors associated with impaired HRQoL 1 year after ICU admission following COVID‐19. Methods This retrospective, cross‐sectional, longitudinal observational study assessed HRQoL 1 year after ICU admission for COVID‐19 during the first wave of the pandemic. …”
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Development of Predictive Nomograms for Clinical Use to Quantify the Risk of Amputation in Patients with Diabetic Foot Ulcer by Bocheng Peng, Rui Min, Yiqin Liao, Aixi Yu

“…To determine the novel proposed nomogram model accuracy in the prediction of the lower-extremity amputations (LEA) risk in diabetic foot ulcer (DFU). Methods and Materials. In this retrospective study, data of 125 patients with diabetic foot ulcer who met the research criteria in Zhongnan Hospital of Wuhan University from January 2015 to December 2019 were collected by filling in the clinical investigation case report form. …”
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Effects of remimazolam and propofol on sleep rhythm and delirium after spinal surgery in elderly patients by Li Yaqiu, Zhou Heng, Wu Ruimin, Wang Xuri

“…Abstract Objective This study aims to investigate the effects of remimazolam on postoperative melatonin secretion, sleep rhythm, and postoperative delirium (POD) in elderly patients undergoing spinal surgery. Methods We selected 120 elderly patients scheduled for elective spinal surgery (lumbar interbody fusion via a posterior approach) under general anaesthesia from November 2023 to January 2024. …”
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