Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…ObjectivesThis study aimed to characterize the genomes of two rare ST592 Klebsiella pneumoniae isolates and to explore their evolution into carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKp).MethodsThe minimum inhibitory concentrations (MICs) were determined using a VITEK 2 compact system. …”
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Interpretable machine learning analysis of environmental characteristics on bacillary dysentery in Sichuan Province by Yao Zhang, Qiao-Lin Wang, Wei Peng, Meng-Yuan Zhang, Yao Qin, Lun Zhang, Rong-Jie Wei, Dian-Ju Kang

“…However, a climate zone-specific predictive model for BD was currently lacking in Sichuan Province.ObjectiveThis study aims to employ interpretable machine learning to explore the influence of environmental factors on BD incidence across different climate zones and to elucidate their interaction mechanisms.MethodsMonthly data on meteorological and ecological factors, along with BD case reports, were collected from 183 counties in Sichuan Province (2005–2023). …”
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Age-Related Differences in the Appetite-Regulating Hormone Response to Exercise by Christoph Höchsmann, Hyeon Jung Heselton, Safiya E Beckford, Jeffrey A French, Jeffrey R Stevens, James L Dorling, Julie B Boron, Karsten Koehler

“…Objectives: We aimed to examine age-related differences in the effect of acute exercise on appetite-regulating hormones. Methods: Participants from 2 age cohorts (younger adults, 19–29 y, n = 39; older adults, 65–75 y, n = 29) completed 2 45-min study conditions on separate days in randomized order: 1) an exercise bout (60% V̇O2peak) on a bicycle ergometer (Exercise), and 2) a seated rest period (Rest). …”
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Efficacy of virtual reality balance training on rehabilitation outcomes following anterior cruciate ligament reconstruction: A systematic review and meta-analysis. by Chao Du, Nei-Meng Gu, Tian-Ci Guo, Ai-Feng Liu

“…<h4>Objective</h4>The objective of this systematic review and meta-analysis is to clarify the rehabilitation efficacy of virtual reality (VR) balance training after anterior cruciate ligament reconstruction (ACLR).<h4>Methods</h4>This meta-analysis was registered in PROSPERO with the registration number CRD42024520383. …”
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Did COVID-19 surveillance system sensitivity change after Omicron? a retrospective observational study in England by Julii Brainard, Iain R. Lake, Roger A. Morbey, Alex J. Elliot, Paul R. Hunter

“…However, surveillance sensitivity may have changed as different variants were introduced to the population, due to greater disease-resistance after comprehensive vaccination programmes and widespread natural infection or for other reasons. Methods Time series data from ten epidemic trackers in England that were available Sept 2021-June 2022 were compared to each other using Spearman correlation statistics. …”
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Association of Risk-Taking Behaviors, Vestibular Provocation and Action Boundary Perception Following Sport-Related Concussion in Adolescents by Shawn R. Eagle, Anthony P. Kontos, Shawn D. Flanagan, Christopher Connaboy

“…<b>Background/Objectives</b>: The purpose of this study was to evaluate the association between risk-taking behaviors, vestibular symptoms/impairment and perception–action coupling behavior in recently concussed adolescents. <b>Methods</b>: This study utilized a cross-sectional design to evaluate the early effects of concussion on 12–18-year-old adolescents (n = 47) recruited from a concussion specialty clinic at their presenting clinical appointment. …”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Aim of the study: to reduce cognitive impairment during laparoscopic cholecystectomy by perioperative administration of drugs with antihypoxic and antioxidant effects under the control of stabilography.   Materials and methods. We studied the effect of general anesthesia and antioxidants on cognitive, static and locomotor functions during laparoscopic cholecystectomy. …”
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Accessibility of Massive Open Online Courses in Computer Sciences and Programming for Persons with Disabilities by E. A. Kosova, A S. Gapon, K. I. Redkokosh

“…At the same time, the specifics of online courses on programming require greater attention to the web content accessibility for persons with disabilities, especially in a program code.Material and methods. The selection of MOOCs was carried out in July 2020 by browsing catalogs of platforms with Russian-language content. …”
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A Prospective Observational Study on the Risk of Contrast-Induced Nephropathy Among Patients Undergoing Fundus Fluorescein Angiography by Niño Carlo M. Naidas, MD, Catherine E. Jordan, MD, Romulo N. Aguilar, MD, Arlene C. Crisostomo, MD

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Persistent cough after segmental resection, an issue that clinicians need to pay more attention to by He Guan, Zhijun Han, Qifei Wan, Qiangwen Huang, Li Wei, Jiwei Li

“…This study aims to explore the risk factors for persistent cough following pulmonary segmentectomy and to establish a predictive model to guide perioperative management.MethodsThis retrospective study included 540 patients who underwent thoracoscopic pulmonary segmentectomy at Zhengzhou University People’s Hospital from February 2024 to January 2025. …”
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Supramalleolar osteotomy outcomes for post-traumatic fracture-related ankle arthritis: a retrospective analysis by Yun-Qing Zhao, Xue-Wen Wang, Heng Li, Xiao-Feng Gong, Yong Wu

“…Abstract Background This study aimed to investigate the early-to-mid-term efficacy of supramalleolar osteotomy (SMO) for the management of post-traumatic ankle arthritis resulting from previous fractures. Methods A retrospective analysis was conducted on the clinical data of 19 individuals with post-traumatic ankle arthritis secondary to old fractures treated with SMO between March 2018 and September 2022. …”
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Mitigating fatigue in long COVID patients with MYPplus: a clinical observation by Yu-Jin Choi, Jin-Seok Lee, Jin-Yong Joung, Seung-Ju Hwang, Young-Yil Kim, Chang-Gue Son

“…This observational study aimed to evaluate the efficacy of MYPplus, an herbal formulation composed of Astragali Radix, Salviae Radix, and Aquilariae Lignum, in alleviating fatigue and brain fog in patients with Long COVID. Methods Subjects with a score of 60 or higher on the Modified Korean version of the Chalder Fatigue scale (mKCFQ11) or a brain fog rating of 5 or higher on the visual analogue scale (VAS) took two capsules of MYPplus (500 mg per capsule) twice daily for 4 weeks. …”
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Spectrum of sonographic changes in hereditary motor and sensory neuropathy with autosomal dominant and X-linked inheritance by E. S. Naumova, D. S. Druzhinin, S. S. Nikitin, S. A. Kurbatov

“…Analysis of quantitative and qualitative ultrasound changes of limb nerves in patients with HMSN type 1 and its comparison with anthropometric and nerve conduction study data.Materials and methods. 44 HMSN patients were analyzed: 16 men, mean age 35,9 ± 6,8 years; 16 (37 %) with autosomal dominant type 1А, 11 (25 %) – with 1В type and 17 (38 %) with Х-linked inheritance. …”
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Integration of multi-omics data reveals dysregulated RNA methylation in retinal pigment epithelium drives age-related macular degeneration by Ya-Jun Gong, Zhi-Lin Zou, Kai-Rui Qiu, Qiang Wang, Xiao-Lai Zhou

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Population Pharmacokinetics and Pharmacodynamics with Enterohepatic Recirculation of Co-Medication of Rosuvastatin and Ezetimibe by An H, Shin D

“…The objective of this study was to develop a population pharmacokinetic/pharmacodynamic (PK/PD) model of the interaction between rosuvastatin and ezetimibe that incorporates enterohepatic recirculation (EHC).Methods: Concentration–time data were obtained from a two-part, open-label, multiple-dose crossover, drug interaction study. …”
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The relationship between diabetes distress and eHealth literacy among patients under 60 years of age with diabetes: a multicenter cross-sectional survey by Haoyang Chen, Bin Wang, Yongqing Liu, Qiaoyun Liu, Jiayan Bai, Lijuan Yao, Biyu Shen

“…Therefore, this study aims to assess the eHealth literacy of diabetes patients and explore its relationship with diabetes distress. Methods This cross-sectional study was conducted from November 2022 to July 2023 and involved 260 diabetes patients from three tertiary hospitals in Nantong, China. …”
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The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021 by Shan Liu, Zhiping Wu, Qingyu An, Jun Wu, Jinjian Bai, Wei Sun, Linan Guo, Luxi Gong

“…BackgroundThis study aimed to analyze the burden, temporal trends and etiologies of diarrhea from 1990 to 2021, and to forecast the burden from 2022 to 2040 in Asia and Asian countries.MethodsData were sourced from the Global Burden of Diseases (GBD) 2021 study. …”
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Surgical Outcomes of Single-Stage Correction Using Cervical Pedicle Screw Fixation Rather Than Lateral Mass Fixation in NF1-Associated Pediatric Cervical Kyphosis by Zeki Boğa, MD, Semih Kıvanç Olguner, MD, Tolga Türkmen, MD, Ümit Kara, MD, Ali Arslan, MD, Mehmet Özer, MD, Ahmet Hamit Çınkı, MD, Yurdal Gezercan, MD

“…To our knowledge, this study is the first to report the clinical outcomes of patients with NF-related cervical kyphosis who underwent stand-alone posterior pedicle fixation surgery. Methods:. The outcomes of 14 patients who underwent surgery using the pedicle screw were retrospectively examined between 2015 and 2022. …”
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Clinical effectiveness observation of transperineal rectocele repair combined with puborectalis muscle release in the treatment of 26 patients with rectocele by Yang Yong, Huang Luqiao, Li Shanshan, Meng Qingliang, Xie Guangwei

“…[Objectives] To analyze the clinical effectiveness of transperineal rectocele repair combined with puborectalis muscle release in the treatment of rectocele. [Methods] We retrospectively analyzed the clinical data of 26 female patients with rectocele who underwent transperineal rectocele repair combined with puborectalis muscle release at the Anorectal Department, Xuzhou Central Hospital from August 2022 to October 2023. …”
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Does the Birthplace Matter for Chinese Pop Music Talents? From the Perspective of Local Cultural Capital by Chen Yifei, He Jinliao

“…Based on cultural capital theory, this paper examines Chinese pop singers by analyzing their birthplaces and their relationship with local cultural capital. Using GIS methods, such as kernel density analysis, the study visualizes the spatial clustering characteristics of Chinese pop singers and explores the factors influencing the spatial distribution of their birthplaces through a negative binomial regression model. …”
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