Effects of a Self-Management Telehealth Program on Improving Strength and Hand Function in Systemic Sclerosis Patients: A Randomized Controlled Trial by Orathai Wantha, Ajanee Mahakkanukrauh, Siraphop Suwannaroj, Kwankaew Tuydaung, Nonglak Methakanjanasak, Kannika Srichomphu, Jinnaphat Kraipoj, Chingching Foocharoen

“…Objective: A self-management telehealth program to improve hand strength and function in systemic sclerosis (SSc) patients may improve their quality of life, so we investigated its efficacy. Methods: A 6-week prospective randomized controlled study was conducted in adults with SSc with a hand mobility in scleroderma (HAMIS) score > 1 or a limited range of motion in at least one hand joint. …”
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Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis by Mahsa Ranjbar, Mehran Rahimlou, Maryam Fallah, Kurosh Djafarian, Hamed Mohammadi

“…We decided to run a systematic review and meta-analysis to investigate the relationship between vitamin D supplementation and the outcomes of adult patients suffering from RA. Methods: We searched electronic databases, using specific search terms in PubMed, Scopus, and ISI Web of Science, until May 2024. …”
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Effect of plasma adsorption and low-volume plasma exchange on intracranial pressure in acute-on-chronic liver failure: a prospective observational study by Yuanji Ma, Ziyan Li, Yan Xu, Shaoqun Zhou, Qi Yang, Lingyao Du, Fang Chen, Lang Bai, Hong Tang

“…The effect of plasma adsorption (PA) and low-volume plasma exchange (PE) on ICP were unclear. Methods A prospective observational cohort study was conducted in patients with acute-on-chronic liver failure (ACLF) receiving PA followed immediately by low-volume PE. …”
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Comparison of the clinical efficacy of patellar lateral retraction and patellar eversion in total knee arthroplasty: a systematic review and meta-analysis by Mingjie Dong, Xiaoyu Sun, Hao Fan, Weiping Ren, Yushan Wang, Yingjie Gao, Pengfei Shao, Yu Gao, Qiang Jiao, Yi Feng

“…Comparisons between the two procedures are inconclusive; therefore, the study purpose was to assess the postoperative clinical efficacy to identify the most suitable procedure. Methods Electronic databases were searched, including Web of Science, ScienceDirect, PubMed, Embase, OVID, the Cochrane Library, CINAHL, CNKI, and WANFANG, to identify clinical trials of PLR versus PE from inception to May 2023. …”
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Assessing Correlations Between Radiographic Classification and Patient-Reported Outcome Measures for Symptomatic Thumb Carpometacarpal Osteoarthritis by Bradley Nelson, MS, Roland Zama, BS, Kavya K. Sanghavi, MPH, Aviram M. Giladi, MD, MS, Kenneth R. Means, Jr., MD

“…Our purpose was to evaluate correlations between baseline radiographic stages and prospectively collected patient-reported outcome measures (PROMs) for CMC OA. Methods: This is a retrospective review of prospectively collected data from a larger observational study of patients aged 35–85 years with newly symptomatic thumb CMC OA. …”
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Lesion assessment in multiple sclerosis: a comparison between synthetic and conventional fluid-attenuated inversion recovery imaging by Roald Ruwen Essel, Britta Krieger, Barbara Bellenberg, Dajana Müller, Theodoros Ladopoulos, Ralf Gold, Ruth Schneider, Carsten Lukas, Carsten Lukas

“…This study compares an established software's performance for automated volumetric and numerical segmentation of MS brain lesions using synthetic T2-weighted fluid-attenuated inversion recovery (FLAIR) MRI, based on a multi-dynamic, multi-echo sequence (MDME), vs. conventional FLAIR imaging.MethodsTo ensure comparability, 3D FLAIR images were resampled to 4 mm axial slices to match the synthetic images' slice thickness. …”
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Fractal phototherapy: impact on the structure and function of the retina of rabbits with modelled retinal pigment epithelium atrophy by D. V. Fadeev, N. V. Neroeva, M. V. Zueva, I. V. Tsapenko, V. I. Kotelin, T. A. Pavlenko, O. V. Beznos, T. D. Okhotsimskaya, P. A. Ilyukhin, Yu. S. Timofeev

“…The purpose of this work is to study the effect of FF on the functional activity and morphology of the retina in rabbits with a model of retinal pathology. Material and methods. We modelled an atrophy of retinal pigment epithelium (RPE) on both eyes of 50 rabbits. 30 days after the administration of bevacizumab, the animals were divided into two groups of 25 animals each. …”
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Analgesic protocol for procedural pain treatment of second-degree burns in children by Komarčević Aleksandar, Jokić Radoica, Pajić Miloš, Jovanović Mladen, Milenković Marina

“…The aim of this study was to determine the effectiveness of analgesic and/or local anesthetic in relieving the intensity of procedural pain. Methods. The study included 120 pediatric patients with second-degree burns who were allocated into four groups of 30 children (control group, groups I, II, and III). …”
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Clinical study on the effect of temporomandibular joint disc anchorage on surface electromyographic characteristics of the masticatory muscles by LIN Yuxiang, LI Chenxi, GONG Zhongcheng

“…[Objective:] To evaluate the effect of temporomandibular joint disc anchorage (DA) on the surface electromyography (sEMG) characteristics of the masticatory muscles and its clinical outcome. [Methods:] A total of twenty-three patients with anterior disc displacement without reduction (ADDwoR) who underwent temporomandibular joint disc anchorage (DA) between December 2022 and January 2024 were collected to compare their preoperative, 3-month postoperative, and 6-month postoperative maximal interincisal opening (MIO), visual analogue scale (VAS) scores, mandibular border movement (BM) distance, and sEMG of anterior temporalis (TA) and masseter muscle (MM). …”
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Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Phar... by Kristina Zarif Attalla, Doaa H. Hassan, Mahmoud H. Teaima, Carol Yousry, Mohamed A. El-Nabarawi, Mohamed A. Said, Sammar Fathy Elhabal

“…<b>Objective</b>: This study aims to develop an intranasal (IN) delivery system for glioblastoma multiforme (GBM) management using repurposed superparamagnetic iron-oxide (SPION) loaded with atorvastatin (ATO)-nanostructured lipid carrier (NLC). <b>Methods</b>: Emulsification and ultrasonication were used to formulate ATO-NLCs, and the best formula was loaded with SPION to make the final atorvastatin/superparamagnetic iron oxide-loaded nanostructured lipid carrier (ASN) formulation. …”
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Faricimab for treatment-resistant choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD): seven-months results using artificial intelligence and... by Anna Heinke, Alexandra Warter, Ines D. Nagel, Akshay Agnihotri, Nehal Nailesh Mehta, Carlo Miguel B. Galang, Daniel N. Deussen, Dirk-Uwe G. Bartsch, Lingyun Cheng, Henry A. Ferreyra, William R. Freeman

“…Abstract Background To analyze the therapeutic response to faricimab 6 mg/0.05 ml in eyes with neovascular AMD (nAMD) with refractory intra- and/or subretinal fluid due to choroidal neovascularization (CNV), previously unresponsive to 4 mg monthly aflibercept and combination therapy with anti-VEGF and long-acting steroids. Methods A retrospective case series study of 22 eyes with unresponsive CNV, despite monthly intravitreal treatment (mean number of pre-faricimab injections: 35.52 ± 17.12). …”
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Evaluation of Comparative Efficacy of Goghrita with Saindhava Matrabasti versus Goghrita Matrabasti in Sciatica (Gridhrasi): A Randomised Controlled Trial Research Protocol by Girish Bhupal, Shweta Parwe, Milind Nisargandha, Shalini Pathania

“…Aim: To evaluate and compare the efficacy of Goghrita (cow clarified butter) with Saindhav Lavana (rock salt) Matrabasti (enema) versus Goghrita Matrabasti in Gridhrasi (sciatica). Materials and Methods: A randomised single-blind (assessor) superiority trial will be conducted at the Department of Panchakarma, Mahatma Gandhi Ayurved College Hospital and Research Centre (MGACHRC), Salod Hirapur (H), Maharashtra, India, from November 2024 to January 2026. …”
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The combination of hot water spray and subzero saline chilling improved chilling efficiency, meat quality, and sensory attributes by K. Kawamura, D. Ma, D.U. Ahn, H.-S. Seo, V. Hogan, L.N. Stephens, J. Moallem, J.W. Jin, I. Kang

“…Summary: Accelerated poultry processing is always desirable when the product quality, visual appearance, and sensory attributes are the same or better than the conventional processing. …”
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The accuracy of asynchronous tele-screening for detecting dental caries in patient-captured mobile photos: A pilot study by Alaa Husni Qari, Moayad Hadi, Alawi Alaidarous, Abdulrahman Aboalreesh, Majed Alqahtani, Ibraheem K. Bamaga, Jilen Patel, Mohamed Estai

“…Objectives: Unaided visual inspection is a primary dental screening technique. …”
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Study on Large‐Scale Brain Network Abnormalities in Patients With Beta‐Thalassemia by Mingrui Yang, Guowei Chen, Peng Peng, Cheng Tang, Chaotian Luo, Fei Peng, Rong Kong, Chunxia Zhu, Jiatong Liang

“…This study systematically evaluates alterations in both intra‐brain network functional connectivity (FC) and inter‐network functional connectivity (FNC) in β‐TM patients using resting‐state functional magnetic resonance imaging (rs‐fMRI) and independent component analysis (ICA), aiming to uncover the potential mechanisms underlying their neurofunctional impairments. Methods This study included 72 β‐TM patients and 50 age‐ and gender‐matched healthy controls (HC). rs‐fMRI was used to collect brain functional data, and ICA was applied to extract 14 resting‐state functional networks (RSNs). …”
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Increasing motivation and well-being among medical students using curricular self-experience group sessions—a randomized controlled trial by Philipp Spitzer, Claire Mittmann, Janine Utz, Stefan Mestermann, Teresa Festl-Wietek, Johannes Kornhuber, Anne Herrmann-Werner

“…Therefore, this pilot study investigates whether promoting relatedness, autonomy and competence through participation in self-experience group therapy increases intrinsic motivation and reduces stress in medical students.Methods A longitudinal randomized controlled trial was conducted with 139 medical students. …”
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Impact of Hip Exercises on Postural Stability and Function in Patients with Chronic Lower Back Pain by Inhwan Leem, Gyu Bin Lee, Ji Won Wang, Sang Woo Pyun, Chang-Jun Kum, Jin Hyuck Lee, Hyeong-Dong Kim

“…<b>Background and Objective:</b> This study aimed to compare functional and clinical outcomes between patients with chronic non-specific lower back pain (NSLBP) with restricted hip extension mobility who performed spinal stabilization exercises with hip mobilization either with or without additional hip exercises. <b>Methods:</b> A total of 42 patients with chronic NSLBP with restricted hip extension mobility were enrolled (21 with and 21 without additional hip exercises). …”
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Optic neuritis in various demyelinating diseases by A. K. Kalashnikova, D. D. Eliseeva, N. A. Andreeva, N. V. Zhorzholadze, I. A. Ronzina, R. Ts. Bembeeva, N. N. Venediktova, M. R. Kalganova, N. L. Sheremet

“…Demyelinating optic neuritis (ON) can be either idiopathic (iDON) or a manifestation of MS, NMOSD (AQP4-ON) or MOGAD (MOG-ON).Objective: to determine the clinical features of ON and to evaluate the diagnostic value of optical coherence tomography (OCT) in demyelinating diseases of the central nervous system.Material and methods. The study included 43 patients with demyelinating ON who were divided into three groups according to the underlying disease (NMOSD, MOGAD and MS/iDON). …”
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity by Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic

“…This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds. Methods: Primary neuronal cultures were prepared from the cortex of newborn pups. …”
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Machine learning–based quantification of overall and internal ultrasound characteristics for diagnosing malignant partially cystic thyroid nodules by Yutong Zhang, Jue Jiang, Aqian Chen, Dong Zhang, Dong Zhang, Lirong Wang, Xin Yuan, Xin He, Shanshan Yu, Juan Wang, Qi Zhou

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