Cell graph analysis in hepatocellular carcinoma: predicting local recurrence and identifying spatial relationship biomarkers by Yizhe Yuan, Ziyin Zhao, Xin Fang, Qing Zhang, Wenqing Zhong, Midie Xu, Gongqi Li, Rushi Jiao, Heng Yu, Ruoxi Wang, Shuyu Liu, Weitao Zu, Bingsen Xue, Yuze Chen, Chengxiang Wang, Ya Zhang, Minghui Liang, Bing Han, Cheng Jin

“…The proposed HGTs outperformed existing SOTA methods, with the C-index improving by 23.1% to reach 0.823, by further integrating multimodal data, including clinical information and immunohistochemical markers. …”
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Determinants of academic performance of healthcare professional students in a medical university, Ajman, United Arab Emirates by Shahnaz Mohamed Wazil, Sathyapriya Nandagopal, Afreen Abdul Rahim Sanaullah, Liju Susan Mathew, Nermine Nosseir, Jayadevan Sreedharan, Jayadevan Sreedharan, Anusha Sreejith, Anusha Sreejith, Latifa Nabeel Alsaad, Latifa Nabeel Alsaad, Jayakumary Muttappallymyalil, Jayakumary Muttappallymyalil

“…Understanding these contributing factors is essential for supporting student success and optimizing educational outcomes.MethodsA cross-sectional study was conducted among 521 healthcare professional students aged 18 and above using a self-administered questionnaire. …”
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The network and interactive pattern of social adjustment and psychological symptoms in patients with spinal cord injury: a network analysis by Hui Liu, Yi Ni, Haixia Xie, Yijun Xie, Chenhui Fan, Yao Li, Weinan Shen, Hua Zhai, Chenghua Jiang, Jing Wu, Hengjing Wu

“…Objective To determine the network structure and interaction patterns of social adjustment and psychological symptoms in patients with spinal cord injury (SCI). Methods A cross-sectional patient-reported study was conducted using an online questionnaire survey disseminated from February to April 2023. …”
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Efficacy and safety of interferon-alpha 1b injection into the intervertebral foramen with ultrasonic guidance in patients with postherpetic neuralgia: study protocol for a randomiz... by Hui-Min Hu, Hui-Min Hu, Wen-Hui Liu, Wen-Hui Liu, Chen Li, Chen Li, Qing Shi, Qing Shi, Chun-Hua Liu, Chun-Hua Liu, An-Xiang Liu, An-Xiang Liu, Yi-Fan Li, Yi Zhang, Peng Mao, Bi-Fa Fan

“…In this study, we aim to evaluate the efficacy and safety of interferon (IFN)-α1b injection into the intervertebral foramen of patients with PHN.Patients and methodsThis is a study protocol for a randomized, double-blind placebo-controlled multicenter clinical trial. …”
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Use and meaning teachers assign to the integration of the MICA 3.0 kit for teaching climate change by Sonia Pino, César Cofre, Humberto Vergara, Luis Vergara, Jaime Solís-Pinilla, Andoni Arenas-Martija, Andoni Arenas-Martija, Andoni Arenas-Martija, Paulina Ampuero, Paulina Ampuero, Cristian Merino, Cristian Merino

“…IntroductionTeaching climate change requires teachers to have the educational resources that will facilitate teaching this content and visualize how a global problem has various local implications. …”
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Low-dose RaDiation therapy for patients with KNee osteoArthritis (LoRD-KNeA): a protocol for a sham-controlled randomised trial by Jiyu Sun, Won Park, Dong Hyun Kim, Ji Hyun Lee, Joon Ho Wang, Hak Jae Kim, Kichul Shin, Min Jung Kim, Ji Young Kim, Byoung Hyuck Kim, Du Hyun Ro, Dae-Hee Lee, Eun-Hee Hong, Seong-Jun Cho, Hyuk-Soo Han

“…The presented trial aims to evaluate the efficacy and safety of LDRT for patients with knee OA.Methods and analysis This prospective, multicentre, randomised trial will be conducted in the Republic of Korea. …”
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Distinguishing features of microvascular abnormalities in high myopia retinoschisis via multimodal imaging by Yunhan Tao, Xuhui Chen, Tao Li, Xian Zhang, Xufang Sun

“…Purpose: To report the differences between microvascular abnormalities (MVAs) and retinal vasculitis in patients with high myopia (HM) and retinoschisis and discuss the efficacy of treatments, including corticosteroids, and posterior vitreous detachment (PVD). Methods: We enrolled seven patients with HM retinoschisis in the Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. …”
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Effect of seasonal exposure in aeroallergen-sensitised patients with irritable bowel syndrome-diarrhoea by Carlo Maria Rossi, Carlo Maria Rossi, Marco Vincenzo Lenti, Marco Vincenzo Lenti, Stefania Merli, Martina Fiorita, Martina Fiorita, Antonio Lo Bello, Antonio Lo Bello, Mario Andrea Latorre, Mario Andrea Latorre, Paola Ilaria Bianchi, Nicola Aronico, Annalisa De Silvestri, Antonio Di Sabatino, Antonio Di Sabatino

“…BackgroundPollen allergy may influence irritable bowel syndrome (IBS) symptoms; however, available data are scant.AimsThis study aims to assess symptom variability in atopic IBS patients.MethodsWe retrospectively analysed consecutive adult IBS patients evaluated between 2021 and 2024. …”
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Quantifying the spatial patterns of retinal ganglion cell loss and progression in optic neuropathy by applying a deep learning variational autoencoder approach to optical coherence... by Jui-Kai Wang, Jui-Kai Wang, Brett A. Johnson, Zhi Chen, Zhi Chen, Honghai Zhang, Honghai Zhang, David Szanto, Brian Woods, Brian Woods, Michael Wall, Young H. Kwon, Young H. Kwon, Edward F. Linton, Edward F. Linton, Andrew Pouw, Mark J. Kupersmith, Mark J. Kupersmith, Mark J. Kupersmith, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Randy H. Kardon, Randy H. Kardon

“…Furthermore, the bVAE model is capable of tracking the spatial pattern of RGC thinning over time and classifying the underlying cause.MethodsThe bVAE model consists of an encoder, a display decoder, and a booster decoder. …”
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The association of heavy metals/metalloid and stroke—Findings in Shanxi, China and the US NHANES from 2011 to 2020 by Yuese Yuan, Li Zhang, Fuying Liu, Haobo Liu, Ying Wang, Xiujuan Yang, Liangpo Liu, Ben Li, Li Wang, Jin Yang, Hongyan Cao, Yulan Qiu, Jinping Zheng, Jian Guo, Yi Gao

“…Background: Previous studies provided contradictory evidence regarding the relationship between metal concentrations and ischemic stroke (IS). Methods: A total of 100 adults with IS were included in this study, as well as an equal number of controls. …”
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HANDEL’S OPERAS IN THE CONTEXT OF CONTEMPORARY DIRECTING: ON THE IMPLEMENTATION OF FILM COMPOSITION PRINCIPLES IN OPERA PERFORMANCES / HÄNDELS OPERN IM KONTEXT MODERNER REGIE: ZUR... by KONSON GRIGORI R., KONSON IRINA A.

“…The core of this concept was “the transition from the Expressive Movement to the image of the art work... as a process of interaction of layers of consciousness” [1, p. 188], which allowed for multiple entries into the artistic image (one of the authors has applied this method of analysis in a work devoted to the integration of the principles of painting and cinema: [2, pp. 63–86]). …”
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Quantification of Plutonium and Americium in Environmental Matrices Using Accelerator Mass Spectrometry by Elena Moroianu, Iuliana Stanciu, Doru Pacesila, Andreea Dima, Oana Gaza, Daniel Vasile Mosu

“…Chemical separation of these isotopes was achieved through ion chromatography, employing reference isotopes <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mmultiscripts><mi>Pu</mi><none></none><none></none><mprescripts></mprescripts><none></none><mn>242</mn></mmultiscripts></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mmultiscripts><mi>Am</mi><none></none><none></none><mprescripts></mprescripts><none></none><mn>243</mn></mmultiscripts></mrow></semantics></math></inline-formula> for method validation. Certified reference materials, including IAEA-410 (Bikini Atoll sediment) and Sample 05, were analyzed to ensure accuracy. …”
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Association between physical activity patterns and the risk of stroke phenotypes: an accelerometer-based prospective cohort study from the UK Biobank by Yiming Shi, Lequn Peng, Fan Xu, Shanyu Peng, Peng Wang, Xiaomeng Huang, Tingting Xiong, Yang Bai, Wei Zhang, Huang Ding

“…Therefore, the aim of this study was to explore the association between different exercise patterns and stroke and its subtypes using exercise data from the UK Biobank. Method This study analyzed data from 90,926 UK Biobank participants with long‐term follow-up (mean ranging from 7.56 to 7.83 years). …”
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A very sharp threshold for first order logic distinguishability of random graphs by Itai Benjamini, Maksim Zhukovskii

“…The proof makes heavy use of the second-moment method. It is delicate, because the construction of the formula depends in an important way on whether $\log_2n-2\log_2(\log n)+\log_2(\log 2)$ is or is not close to an integer. …”
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Fluticasone propionate in chronic rhinosinusitis with nasal polyps (CRSwNP): an artificial intelligence-driven consensus by Emilio Avallone, Raffaella Iannella, Antonella Di Lullo, Michele Grasso, Salvatore Musto, Enzo Piermichele Troncone, Giuseppe Tortoriello, Bernardino Cassiano, Simona Nappi, Gianluca Bava, Giovanna Piazzetta, Giovanni Tomacelli, Aurelio D’Ecclesia, Giacomo Spinato, Giacomo Matrone, Doriano Politi, Carlo De Luca, Claudio Caporale, Livio Presutti, Livio Presutti, Gabriele Molteni, Gabriele Molteni, Ernesto Pasquini, Francesco Panu, Simonetta Masieri, Stefano Di Girolamo, Giulio Cesare Passali, Luca de Campora, Giandomenico Maggiore, Domenico Di Maria

“…However, the need for a consensus on its use stems from the increasing focus on optimizing topical therapies to improve clinical outcomes and minimize systemic side effects.Materials and methodsThe Butterfly Decisions AI platform facilitated the collection and integration of evaluations and feedback, facilitating an expert consensus on 13 statements.ResultsThe participants agreed highly on the different statements. …”
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Gender-specific association of STON2 rs2371597 polymorphism in keratoconus patients of Saudi origin by Altaf A. Kondkar, Altaf A. Kondkar, Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Tanvir Khatlani, Glenn P. Lobo, Hatem Kalantan, Saleh A. Al-Obeidan, Saleh A. Al-Obeidan, Abdulrahman M. Al-Muammar

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Prevalence of periodontitis based on retrospective radiographic evaluation at dental hospital in Eastern Province of Saudi Arabia: A retrospective study by Afsheen Tabassum, Marwa Madi, Ahmed Alabdulaziz, Yousif Al Nasrallah, Mohammed Alabdulaziz, Intisar Ahmad Siddique, Farhat Kazmi

“…Our aim was to measure the prevalence of periodontitis and associated risk factors among the Saudi population in the Eastern Province of Saudi Arabia who visited the University Dental Hospital. Methods: In this retrospective study, the demographic data and medical and dental records of 700 subjects were examined. …”
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Progesterone peak influences embryonic developmental morphokinetics on trigger day? A retrospective study by D. Baldini, V. M. Bartoli, A. Mastrorocco, D. Ferri, M. Dellino, A. S. Laganà, S. Hatirnaz, G. M. Baldini, A. Malvasi, A. Vimercati, G. Trojano

“…Aim of the study is to evaluate the impact of PPR exceeding 1.5 ng/ml at the time of hCG-trigger on embryo morphokinetic parameters and to identify predictive biomarkers of in IntraCytoplasmic Sperm Injection (ICSI) cycles outcomes. Methods It is a retrospective study including patients underwent ICSI cycles in the period 2020–2023. 58 patients were recruited in the study group showing P levels in the trigger day greater than or equal to 1.5 ng/ml. …”
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Mid-Term Impact of Conduction System Pacing on Overall Cardiac Performance: A Non-Randomized, Prospective, Single-Center Echocardiographic Study by Catalin Pestrea, Ecaterina Cicala, Roxana Enache, Marcela Rusu, Radu Gavrilescu, Adrian Vaduva, Madalina Ivascu, Florin Ortan, Dana Pop

“…</b> HBP and LBBAP are equally protective for harmful changes in both atria and ventricles. …”
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Seroprevalence of Leptospirosis among High-Risk Individuals in Morocco by Mohamed El Azhari, Mathieu Picardeau, Imad Cherkaoui, Mohamed Anouar Sadat, Houda Moumni, Kamal Marhoum El Filali, Hassan Ghazal, Abderrahmane Maaroufi, Salsabil Hamdi, Naima El Mdaghri, Pascal Bourhy

“…A cross-sectional study was performed between 17 and 23 February 2014 to estimate the seroprevalence of leptospirosis among high-risk populations in Casablanca (Morocco). Methods. A total of 490 human serum samples (97.6% males) were collected in 3 high-risk occupational sites including the biggest meat slaughterhouse (n = 208), a poultry market (n = 121), and the fish market (n = 161). …”
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