Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study by Liu C, Wang Y, Yin Y, Wang P, Ji X, Sun J, Zhao S, Jia Y, Liu S, Zhou Z

“…Cuicui Liu,1,* Yanting Wang,1,* Yanwei Yin,2 Pei Wang,1 Xiangyu Ji,1 Jian Sun,1 Shuo Zhao,1 Yanfang Jia,1 Shanling Liu,1 Zangong Zhou1 1Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China; 2Pain Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zangong Zhou, Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, 266000, People’s Republic of China, Tel +86 532-82912511, Email zhouzangong@qdu.edu.cnPurpose: This randomized, controlled trial aimed to assess the sedative effects of esketamine and sufentanil combined with propofol during EUS.Patients and Methods: Three hundred and forty patients undergone EUS were randomly divided into two groups to receive esketamine 0.25 mg/kg combined with propofol (esketamine group) or sufentanil 0.1 μg/kg combined with propofol (sufentanil group). …”
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Efficacy of neck-mounted lazy holder for smartphones on cervical pain and function in patients with non-specific neck pain by Omnia Mohamed Mohamed Abdel Moneim, Ragia Mohamed Kamel, Mohamed Ibrahim Abdelhay

“…The study aimed to explore clinical benefits of addressing daily postural habits by integrating an ergonomic accessory called neck-mounted smartphone holder. Methods The study included 40 patients aged 18–45 years diagnosed with NSNP who used a smartphone at least 6 h a day, recruited from the outpatient clinics of faculty of physical therapy at Benha University and they were randomly allocated to two equal groups. …”
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Correlation Between Gastroesophageal Reflux Disease and Small Intestinal Bacterial Overgrowth: Analysis of Intestinal Microbiome and Metabolic Characteristics by Wang ZT, Tan WT, Huang JL, Zhang PF, Li Q, Wang MM, Meng MM, Su H, Guo CM, Liu H

“…We also explore changes in gut microbiota and metabolism in patients with both conditions.Methods: This study included patients from the Department of Gastroenterology, Beijing Shijitan Hospital, between February 2021 and November 2023. …”
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Biomarkers for Early Predicting In-Hospital Mortality in Severe Fever with Thrombocytopenia Syndrome and Differentiating It from Hemorrhagic Fever with Renal Syndrome by Chen C, Zheng Y, Li X, Shen B, Bi X

“…This study used routine laboratory parameters, epidemiology and clinical manifestations to develop a model for the early diagnosis of SFTS and identify fatal risk factors, ultimately reducing mortality of SFTS.Patients and Methods: This retrospective cohort study included 141 SFTS and 141 HFRS patients. …”
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Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study by Alka S Gupta, Geeta S Kulkarni, Suraj D Bhame

“…Objectives: This study was done to find the effectiveness of level two anomaly scan in detection of congenital anomalies and also to find the maternal and neonatal factors associated with congenital anomalies. Methods: Pregnant women with gestational age of more than or equal to 18 weeks were included in the study. …”
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Exploration of the Application Rules and Clinical Significance of Acupoints in Acupuncture Treatment of Migraine Based on Data Mining by He Y, Wang X, Liu M, Li L, Han T, Wu Y, Li X

“…However, as each acupoint elicits distinct analgesic pathways and acupuncturists vary in their acupoint selection, there is currently an absence of evidence-based guidance for determining the optimal acupoint selection.Objective: The aim of this study was to conduct an initial comprehensive data mining analysis to identify the most effective acupoints and their combinations for migraine treatment.Methods: A comprehensive search was carried out in eight electronic bibliographic databases (PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Literature Database, and Chongqing VIP Database) from their inception up to May 2025. …”
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The effect of 8 weeks of aquatic and land exercise training on balance and proprioception of the ankle joint in children with diplegia cerebral palsy by Hamid Abbasi, Hossein Ghasemsharifi, Saeed Abedinzadeh, Reza Sharifatpour

“…The aim of this study was to investigate the effects of a functional training protocol combining water and land exercises on the balance and proprioception of the lower limbs of children with cerebral palsy and diplegia.Materials and Methods: Thirty children with diplegia cerebral palsy were selected through available sampling and randomly divided into two equal groups of experimental (age, 9.33±1.63 years; height, 1.32±0.06 m; weight, 33.88±3.63 kg) and control group (age, 9.46±1.30 years; height, 1.30±0.05 m; weight, 32.04±3.52 kg). …”
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The effects of different caloric restriction diets on anthropometric and cardiometabolic risk factors in overweight and obese females by Mraović Tatjana, Radaković Sonja, Ristić-Medić Danijela, Tepšić-Ostojić Vesna, Rađen Slavica, Hajduković Zoran, Čairović Aleksandra, Miljanović Gora

“…The aim of this study was to investigate the effect of well-balanced different caloric restriction (CR) diets on anthropometric parameters and standard biochemical cardiovascular risk markers [lipid profile, glucose homeostasis and high sensitivity C-reactive protein (hs-CRP)] in overweight/obese females. Methods. Participants (age 20– 40 years) were randomized into 3 different CR diet groups: the group I – restriction of 20% calories from baseline energy requirements, the group II – restriction of 50% calories from baseline energy requirements and the group III – alternating daily diets with 70%/30% restriction. …”
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Risk Factors and Predictive Model for Stress Hyperglycemia After Cardiac Surgery in Non-Diabetic Patients by Zhang M, Wu J, Wang L, Huang H, Duan H, Xue F

“…Mengli Zhang,1,* Jinyan Wu,1,* Lulu Wang,2 Hui Huang,2 Huan Duan,3 Fang Xue1 1School of Nursing, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 3Intensive Care Unit, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Xue, School of Nursing, Bengbu Medical University, Bengbu, Anhui, 233030, People’s Republic of China, Email 0700036@bbmu.edu.cn Huan Duan, Intensive Care Unit, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China, Email duanhuan886@sina.comObjective: To create and verify a model that predicts the risk of stress hyperglycemia (SHG) in patients without diabetes after cardiac surgery.Design: Retrospective analysis.Methods: This retrospective analysis analyzed patients without diabetes post cardiac surgery at our hospital between June 2020 and December 2023. …”
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Combining Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation to Uncover the Efficacy and Mechanisms of Si-Miao-Yong-An Decoction in... by Zhang S, Shao Y, Jin R, Ma B

“…This study aimed to investigate the therapeutic potential of SMYA in promoting diabetic wound healing and to elucidate the underlying molecular mechanisms.Methods: The wound healing effects of SMYA were evaluated in db/db diabetic mice by measuring wound closure rates and histological characteristics, including epidermal thickness and collagen deposition. …”
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Potentially Inappropriate Use of Transdermal Fentanyl in Working-Age and Older Adult Populations with Non-Cancer Pain: Nationwide Cross-Sectional Study by Seunghyun Cheon, Seo-Yong Choi, Kyu Ri Kim, Han-Gon Choi, Jee-Eun Chung

“…ObjectiveOur objective was to investigate the trends in the use of FTD and to evaluate potentially inappropriate FTD use in patients with noncancer pain, based on established evaluation criteria, referring various recommendations and guidelines. MethodsA nationwide cross-sectional study was conducted using a national insurance claims database from 2014 to 2020. …”
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Cognitive performance and associated factors among primary school children in artisanal and small-scale gold mining communities in northwestern Tanzania by Joel L. Maduhu, Elias C. Nyanza, Theresia Maduka, Neema Kayange

“…The study determined the prevalence of cognitive deficits and associated factors among primary school children aged 8–12 years in artisanal and small-scale gold mining (ASGM) communities where exposure to toxic chemical elements is common. Methods A cross-sectional school-based study was conducted in areas with and without artisanal and smallscale gold mining in northwestern Tanzania between 2017 and 2018. …”
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Cholera Outbreak in Chienge District, Luapula Province, Zambia- 31st May – 9th June 2023: Re-emerging threat by Miss Tebello Kolobe

“…This study aimed to describe cases, identify the cause, and risk factors, and propose control measures. Methods: An outbreak investigation followed by a 1: 2 matched case-control study were conducted. …”
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Oral Health Status in the Iranian Elderly: The Role of Nutrition Status and Health Literacy by Shahab Papi, Manijeh Izadi, Leila Behboodi, Zahra Taheri-Kharameh, Fatemeh Hosseini, Mahdi Yousefi, Zeynab Karimi

“…Objective: This study aimed to determine oral health status and the relationship between health literacy and nutritional status in the elderly referring to health centers in Tabriz City, Iran. Materials and Methods: This research is a cross-sectional analytical study performed on 300 older people in Tabriz in 2020. …”
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Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression by Simon Gebremeskel, Adam Nelson, Brent Johnston, Brian D Lichty

“…It is likely that novel and combined therapies will be needed to achieve clinical benefits.Methods Using experimental mouse models of pancreatic ductal adenocarcinoma, we examined natural killer T (NKT) cell activation therapy in combination with a recombinant oncolytic vesicular stomatitis virus (VSVΔM51) engineered to express the cytokine IL-15 (VSV-IL-15). …”
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Cholesterol-Rich Antibiotic-Loaded Liposomes as Efficient Antimicrobial Therapeutics by Natsaridis E, Gkartziou F, Mouzoura P, Mourtas S, Papadia K, Kolonitsiou F, Klepetsanis P, Dermon CR, Spiliopoulou I, Antimisiaris SG

“…In this study, we investigated the effects of cholesterol (Chol) content of liposomes, liposome concentration, and surface coating with polyethylene glycol (PEG) on the antimicrobial activity of moxifloxacin (MOX) liposomes against Staphylococcus epidermidis (ATCC 35984) (S.e).Methods: MOX-liposome compositions with increasing Chol content were evaluated for their susceptibility to planktonic S.e (growth inhibition, killing, and live-dead staining), as well as against pre-formed biofilms (crystal violet, MTT assay, and confocal microscopy). …”
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A formal notation of legal rules applicable in the local space by Anna M. Barańska, Konrad Eckes

“…This approach to law allows for space management using IT methods. The notation of the spatial structure and of legal relationships related to time enable the definition of rules of conduct for diverse groups of local societies. …”
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A comparative study of student performance in all-ceramic crown preparation by clinical-phase students by Abdulkarim H. Alshehri, Mohammed M. Al Moaleem, Abdullah Ahmed Meshni, Thrya S. Gadah, Nasser M. Alahmari, Nassreen H. Albar, Hafiz Ahmed A. Adawi, Bandar M. A. AL-Makramani, Mosa A. Shubayr, Kulashekar Reddy Nandalur

“…Abstract Background Given ongoing discussions about potential gender disparities in clinical skill assessments within dental education, this study aimed to evaluate whether an analytic rubric could provide objective, equitable evaluation of all-ceramic crown preparations among male and female dental students. Materials and methods An analytical rubric for the evaluation of all-ceramic preparation steps was utilized in a clinical course study with two evaluators. …”
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Alterations in White Matter Structure in Sleep-Related Epilepsies: A TBSS-Based Diffusion Tensor Imaging Study by Wang Z, Liu W, Feng X, Wang Q, Ning X, Xing W

“…Ziyun Wang,1,2,* Weiping Liu,3,* Ximei Feng,4 Qian Wang,1,2 Xun Ning,1,2 Wu Xing1,2 1Department of Radiology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 2National Clinical Research Centre for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 3Department of Neurology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 4Department of Radiology, Changsha Central Hospital, University of South China, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wu Xing, Department of Radiology, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, People’s Republic of China, Email xingwu@csu.edu.cnPurpose: The study aims to further investigate the relationship between the Sleep-related epilepsies (SRE) and alterations in the White Matter (WM) microstructure, as well as to explore the clinical value of diffusion tensor imaging (DTI) in patients with SRE.Methods: DTI data were acquired for 52 patients with SRE and 74 Healthy Controls (HC), all of whom were matched for sex and age. …”
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Development and validation of BCG vaccine‐induced novel granulomatous liver injury preclinical animal model by Swati Sharma, Abhishek Moudgil, Jyoti Grewal, Pankaj Khatri, Vishal Sharma, Madhumita Premkumar, Amanjit Bal, Dibyajyoti Banerjee, Amol N. Patil

“…The present study aimed to establish a preclinical model of granulomatous hepatitis by using the BCG (Bacillus Calmette‐Guérin) vaccine, further studying it in the presence of ATT dosing, and analyze the pharmacokinetics of isoniazid, rifampicin, and their respective primary metabolites. Methods We used 56 rats in seven equal groups. Group I functioned as a normal control (NC) receiving normal saline only. …”
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