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28321
LASER THERAPY FOR MANAGEMENT OF CEREBRAL DYSFUNCTION IN CASES OF ACUTE SEVERE PANCREATITIS
Published 2018-07-01“…Pancreatic encephalopathy is one of particular manifestations of this syndrome.Aim of study: to determine severity of cerebral dysfunction in cases of acute destructive pancreatitis, to assess the efficacy of laser therapy for this disease.Material and methods: The research is based on the results of clinical studies, carried out at the Republican Clinical Hospital No.3. …”
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28322
Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury
Published 2024-12-01“…However, the potential mechanism of Cur in alleviating AKI ferroptosis remains unknown.Objective: This study aims to investigate the effects of Cur on AKI ferroptosis.Methods: Folic acid (FA)-induced AKI mouse model and erastin/(rsl-3)-induced HK-2 model were constructed to assess the renoprotection of Cur. …”
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28323
Construction and Comparison of Machine Learning-Based Risk Prediction Models for Major Adverse Cardiovascular Events in Perimenopausal Women
Published 2025-01-01“…Therefore, this study explores the factors influencing the occurrence of MACE in perimenopausal women and establishes a prediction model for MACE risk factors using three algorithms, comparing their predictive performance.Patients and Methods: A total of 411 perimenopausal women diagnosed with MACE at the Binzhou Medical University Hospital were randomly divided into a training set and a test set following a 7:3 ratio. …”
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28324
Utility of the Basophil Reactivity Test in the Clinical Management of People with Severe Uncontrolled Asthma
Published 2025-04-01“…The aim of this study was to evaluate the utility of basophil reactivity, measured through the basophil activation test (BAT), as a marker of response to mAbs.Methods: We measured basophil reactivity, using anti-immunoglobulin E (anti-IgE) antibodies as a stimulus, in 72 consecutive patients with severe uncontrolled asthma before initiation of treatment with mAbs. …”
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28325
Study of Feasibility and Safety of Higher-Dose Dexmedetomidine in Special Outpatient Examination of Pediatric Ophthalmology
Published 2019-01-01“…To investigate the feasibility and safety of higher-dose dexmedetomidine in ophthalmological outpatient examination of children with cataract. Methods. 100 cases of children were recruited in the study and randomly equally divided into two groups. …”
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28326
Challenges in Traditional Chinese Medicine Clinical Trials: How to Balance Personalized Treatment and Standardized Research?
Published 2025-07-01“…The introduction of this framework effectively integrates the traditional characteristics of TCM with modern scientific methods, providing essential theoretical support and innovative solutions for the design and implementation of TCM clinical research, thereby enhancing TCM’s role in global health.Keywords: traditional Chinese medicine, TCM, clinical research, randomized controlled trials, RCT, TCM clinical trials, personalized treatment, standardized research…”
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28327
Associations Between Body Mass Index (BMI) and Dyslipidemia: Results From the PERSIAN Guilan Cohort Study (PGCS)
Published 2025-02-01“…Therefore, the objective of this study was to examine the associations between BMI and dyslipidemia in the Prospective Epidemiological Research Studies in Iran (PERSIAN) Guilan Cohort study (PGCS) population. Methods This cross‐sectional study analyzed the demographic and biochemical data from 10,519 participants of the PGCS population. …”
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28328
Boron adsorption in semiarid Mediterranean soils under the influence of background electrolytes
Published 2022-10-01“…These three latter factors influence boron adsorption, which also influence the availability for plants.METHODS: A study was carried out on boron adsorption at different shaking time intervals (1, 3, 6 and 9 hours) in two soils of different textures in the absence and presence of different background electrolytes solutions (0.02 N CaCl2, 0.02 N MgCl2 , 0.02 N sodium chloride and 0.02 N potassium chloride.FINDINGS: The soil-A (clay loam) adsorbed more boron than soil-B (sandy loam). …”
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28329
Pecularities of Specialists Training in Laboratory Diagnostic in the Context of Integration into the European Higher Education Environment
Published 2012-12-01“…In Ukraine, the educational qualification (EQ) "bachelor" and "master" are differentiated into a basic higher education (which allows specialists to solve typical professional tasks) and complete higher education (with obtaining in-depth knowledge of special skills and innovative methods of solution for the high-level professional problems). …”
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28330
CT-Detected Arterial Calcification and Ischemic Cardiovascular Risk Assessment in Patients with Upper Urinary Tract Calculi: A Case-Control Study
Published 2025-04-01“…This study aimed to investigate the relationship between AC detected by CT in UUTC patients and the risk of ischemic cardiovascular diseases (ICVD).Methods: In this retrospective case-control study, clinical data of 596 patients were collected. …”
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28331
Genotypic diversity and antimicrobial resistance determinants in Salmonella Typhi isolated from children living in informal settlements in Nairobi, Kenya
Published 2025-03-01“…Typhi from sick and asymptomatic children in Mukuru and Kibera informal settlements in Nairobi County. Methods: From 2013 to 2018, children ≤ 16 years presenting to 4 health facilities in Nairobi County were recruited if they had a fever; ≥380C with or without diarrhea. …”
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28332
Investigating the effect of echinacea extraction syrup on the outcomes of lower respiratory infections in patients with COVID-19: a randomized clinical trial study
Published 2024-12-01“…This study was conducted with the aim of determining the effect of Echinacea extract syrup on the outcomes of the lower respiratory tract in patients with COVID-19. Methods In this single-blind randomized controlled trial, 40 patients with COVID-19 who were inpatients in the hospitals of Mashhad University of Medical Sciences, Iran, were randomly selected and assigned to two equal control and experimental groups (n = 20). …”
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28333
Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Lea...
Published 2025-01-01“…We aim to screen and validate the signature genes of BPD by bioinformatics and in vivo experiment.Methods: GSE8586 was obtained from the Gene Expression Omnibus (GEO) database. …”
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28334
Comparison of Point-of-Care and Highly Sensitive Laboratory Troponin Testing in Patients Suspicious of Acute Myocardial Infarction and Its Efficacy in Clinical Outcome
Published 2022-01-01“…The primary and secondary outcomes were the diagnostic performance of POC-cTnI in diagnosing acute myocardial infarction (AMI) and major adverse cardiovascular events (MACE) during 30 days, respectively. Materials and Methods. In this diagnostic accuracy study, 136 patients with suspected ACS who were referred or admitted to the Al Zahra Hospital, Shiraz, Iran, were included between March (2020) and July (2020). …”
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28335
Rotavirus breakthrough infections responsible for gastroenteritis in vaccinated infants who presented with acute diarrhoea at University Teaching Hospitals, Children's Hospital in...
Published 2021-01-01“…This study aimed to characterise the rotavirus genotypes which were responsible for diarrhoeal infections in vaccinated infants aged 2 to 12 months and to determine the relationship between rotavirus strains and the severity of diarrhoea in 2016.<h4>Methods</h4>Stool samples from infants aged 2 to 12 months who presented to the hospital with acute diarrhoea of three or more episodes in 24 hours were tested for group A rotavirus. …”
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28336
Fibrinogen-to-Albumin Ratio as a Novel Predictor of Intracerebral Hemorrhage in Maintenance Hemodialysis Patients
Published 2025-06-01“…The fibrinogen-to-albumin ratio (FAR), a composite inflammatory and nutritional marker, may offer predictive value for ICH in this high-risk population.Methods: This retrospective study analyzed a total of 536 MHD patients (ICH group: n=207; non-ICH group: n=329) from June 2019 to June 2024. …”
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28337
Boosting Hydroxyl Radical Generation with Nitrogen Vacancy&ndash;Modified Carbon Nitride for Triggering Dual Damage of Cancer Nucleus DNA&ndash;Mitochondria against Hypoxic...
Published 2025-07-01“…A hypoxic tumor microenvironment is the bottleneck of photodynamic therapy (PDT) and significantly weakens overall therapeutic efficacy.Methods: In this study, we introduce nitrogen vacancy–modified PCN (NV-PCN), a novel metal-free and O2-independent photosensitizer designed for PDT. …”
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28338
Estimating the risk of zoonotic transmission of swine influenza A variant during agricultural fairs in the United States: a mathematical modeling
Published 2025-04-01“…We investigate the transmissibility of influenza A variant from pigs to humans using epidemiological data from a 2011 zoonotic outbreak of an influenza H3N2 variant during an agricultural county fair in Pennsylvania.MethodsWe developed a mathematical model for the transmission of a swine influenza pathogen among pigs and humans at an agricultural fair. …”
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28339
Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review
Published 2025-04-01“…We aim to conduct a systematic review and meta-analysis comparing the long-term oncologic and renal function outcomes of KSS with those of radical nephroureterectomy (RNU) for UTUC.Materials and methodsA literature search was conducted on PubMed, Embase, and Web of Science in January 2024. …”
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28340
Digital mapping of Ghana’s soil properties and nutrients: performance of spline and weighted average approaches
Published 2025-07-01“…This involved two profile data harmonization methods—equal-area spline and thickness-weighted average—with a quantile random forest model. …”
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